Why Use Cultrex UltiMatrix Reduced Growth Factor Basement Membrane Extract (RGF BME) for Organoids?
Cultrex UltiMatrix RGF BME meets the cell culture scaffolding demands of stem cell and organoid researchers by delivering an extracellular matrix substrate that contains a high protein concentration, optimized stiffness, reduced growth factor composition, and consistent performance in 3D and 2D cell culture applications. With rigorous quality control testing against standard and difficult-to-grow 3D tissue culture, Cultrex UltiMatrix has proven resilience that supports dome formation for organoid culture, ultra-low adhesion embedding for spheroids, and thin-layer coating for embryonic (ESC) or induced pluripotent stem cell (iPSC) expansion and maintenance.
Be the first to enhance the performance and consistency of your organoid, spheroid, and pluripotent stem cell cultures by using the newest and most optimized Cultrex BME matrix from R&D Systems!
Cultrex UltiMatrix RGF BME provides:
- Optimized extracellular matrix composition
- Consistent elastic modulus & gelation rates
- Tensile strength optimized for 3D applications
- High protein concentration (> 9 mg/mL)
- Low endotoxin
- Reduced growth factor formulation
- Consistent performance in organoid and pluripotent stem cell applications
Human Descending Colon (hDC) Organoids Grown on Cultrex UltiMatrix RGF BME. Organoids were harvested following 30 days in culture for imaging and analysis. A) Brightfield images of hDC organoid embedded in Cultrex UltiMatrix. B) hDC organoid stained with Mouse Monoclonal MUC2 Antibody (Catalog # NBP2-4431), Human/Mouse E-Cadherin Antibody (Catalog # AF748), and DAPI (Catalog # 5748)
No purchase necessary. This promotion is available in the US, Canada, and Europe. Sample requests will be honored while supplies last. The sample is the Cultrex UltiMatrix RGF BME (Catalog # BME001). Limit one free sample per customer. Offer void where prohibited, licensed or restricted by federal, state, provincial, or local laws or regulation or agency/institutional policy. Other restrictions may apply.