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Human IL-6 DuoSet ELISA

DY206 234 Citations 9 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
DY206
DY206-05
Ancillary Products Available
DY008: DuoSet ELISA Ancillary Reagent Kit 2
Human IL-6 ELISA Standard Curve
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Product Details
Procedure
Citations (234)
FAQs
Supplemental Products
Reviews (9)
Summary Product Features Kit Content Other Reagents Required Data Examples Product Datasheets Preparation and Storage Background

Human IL-6 DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Sufficient Materials
For five or fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human IL-6. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

 

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

 

  

Data Example

Human IL-6 ELISA Standard Curve View Larger

Human IL-6 ELISA Standard Curve

Product Datasheets

Product Datasheet
COA
SDS

Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-6

Interleukin 6 (IL-6) is a pleiotropic, a-helical, 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. Mature human IL-6 is 183 amino acids (aa) in length and shares 39% aa sequence identity with mouse and rat IL-6. Alternative splicing generates several isoforms with internal deletions, some of which exhibit antagonistic properties. Cells known to express IL-6 include CD8+ T cells, fibroblasts, synoviocytes, adipocytes, osteoblasts, megakaryocytes, endothelial cells (under the influence of endothelins), sympathetic neurons, cerebral cortex neurons, adrenal medulla chromaffin cells, retinal pigment cells, mast cells, keratinocytes, Langerhans cells, fetal and adult astrocytes, neutrophils, monocytes, eosinophils, colonic epithelial cells, B1 B cells and pancreatic islet beta cells. IL-6 production is generally correlated with cell activation and is normally kept in control by glucocorticoids, catecholamines, and secondary sex steroids. Normal human circulating IL-6 is in the 1 pg/mL range, with slight elevations during the menstrual cycle, modest elevations in certain cancers, and large elevations after surgery.

IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R alpha) and a signal transducing subunit (gp130). IL-6 binds to IL-6 Ra, triggering IL-6 Ra association with gp130 and gp130 dimerization. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 Ra are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 Ra elicit responses from gp130-expressing cells that lack cell surface IL-6 Ra. Trans-signaling enables a wider range of cell types to respond to IL-6, as the expression of gp130 is ubiquitous, while that of IL-6 Ra is predominantly restricted to hepatocytes, monocytes, and resting lymphocytes. Soluble splice forms of gp130 block trans-signaling from IL-6/IL-6 Ra but not from other cytokines that use gp130 as a co-receptor.

IL-6, along with TNF-a and IL-1, drives the acute inflammatory response. IL-6 is almost solely responsible for fever and the acute phase response in the liver, and it is important in the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. When dysregulated, it contributes to chronic inflammation in conditions such as obesity, insulin resistance, inflammatory bowel disease, arthritis, and sepsis. IL-6 modulates bone resorption and is a major effector of inflammatory joint destruction in rheumatoid arthritis through its promotion of Th17 cell development and activity. It contributes to atherosclerotic plaque development and destabilization as well as the development of inflammation-associated carcinogenesis.

Long Name:
Interleukin 6
Entrez Gene IDs:
3569 (Human); 16193 (Mouse); 24498 (Rat); 399500 (Porcine); 280826 (Bovine); 403985 (Canine); 100034196 (Equine); 493687 (Feline); 463288 (Primate); 100008733 (Rabbit)
Alternate Names:
B cell stimulatory factor-2; B-cell differentiation factor; BSF2; BSF-2; BSF2CTL differentiation factor; CDF; HGFHSFIFNB2Hybridoma growth factor; IFNB2; IFN-beta-2; IL6; IL-6; IL-6B-cell stimulatory factor 2; Interferon beta-2; interleukin 6 (interferon, beta 2); interleukin BSF-2; interleukin-6; MGI-2A

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

 

Citations for Human IL-6 DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

234 Citations: Showing 1 - 10
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  1. Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection
    Authors: I Santecchia, F Vernel-Pau, O Rasid, J Quintin, M Gomes-Sole, IG Boneca, C Werts
    PLoS Pathog., 2019;15(5):e1007811.
    Species: Human
    Sample Types: Cell Culture Supernates
  2. R. nukuhivensis acts by reinforcing skin barrier function, boosting skin immunity and by inhibiting IL-22 induced keratinocyte hyperproliferation
    Authors: F Abdallah, G Lecellier, P Raharivelo, C Pichon
    Sci Rep, 2019;9(1):4132.
    Species: Human
    Sample Types: Cell Culture Supernates
  3. Blood inflammatory and endothelial markers in women with von Willebrand disease
    Authors: I Govorov, K Bremme, A Larsson, M Holmström, E Komlichenk, R Chaireti, M Mints
    PLoS ONE, 2019;14(1):e0210544.
    Species: Human
    Sample Types: Plasma
  4. Effects of continuous moderate exercise with partial blood flow restriction during hemodialysis: A protocol for a randomized clinical trial
    Authors: RK Cardoso, AM Araujo, RB Orcy, M Bohlke, JP Oses, FB Del Vecchi, FC Barcellos, MC Gonzalez, AJ Rombaldi
    MethodsX, 2019;6(0):190-198.
    Species: Human
    Sample Types: Serum
  5. Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes
    Authors: CR Ojha, M Rodriguez, MKM Karuppan, J Lapierre, F Kashanchi, N El-Hage
    PLoS ONE, 2019;14(2):e0208543.
    Species: Human
    Sample Types: Cell Culture Supernates
  6. D-2-Hydroxyglutarate and L-2-Hydroxyglutarate Inhibit IL-12 Secretion by Human Monocyte-Derived Dendritic Cells
    Authors: I Ugele, ZE Cárdenas-C, K Hammon, M Wehrstein, C Bruss, K Peter, K Singer, E Gottfried, J Boesch, P Oefner, K Dettmer, K Renner, M Kreutz
    Int J Mol Sci, 2019;20(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  7. Cancer-associated fibroblasts induce epithelial-mesenchymal transition of bladder cancer cells through paracrine IL-6 signalling
    Authors: CR Goulet, A Champagne, G Bernard, D Vandal, S Chabaud, F Pouliot, S Bolduc
    BMC Cancer, 2019;19(1):137.
    Species: Human
    Sample Types: Cell Culture Supernates
  8. Large-scale secretome analyses unveil the superior immunosuppressive phenotype of umbilical cord stromal cells as compared to other adult mesenchymal stromal cells
    Authors: A Islam, I Urbarova, JA Bruun, I Martinez-Z
    Eur Cell Mater, 2019;37(0):153-174.
    Species: Human
    Sample Types: Cell Culture Supernates
  9. Human Blood and Tonsil Plasmacytoid Dendritic Cells Display Similar Gene Expression Profiles but Exhibit Differential Type I IFN Responses to Influenza A Virus Infection
    Authors: S Vangeti, J Gertow, M Yu, S Liu, F Baharom, S Scholz, D Friberg, M Starkhamma, A Ahlberg, A Smed-Sören
    J. Immunol., 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  10. An in vitro investigation of the inflammatory response to the strain amplitudes which occur during high frequency oscillation ventilation and conventional mechanical ventilation
    Authors: C Harris, SD Thorpe, S Rushwan, W Wang, CL Thompson, JL Peacock, MM Knight, B Gooptu, A Greenough
    J Biomech, 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  11. In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists
    Authors: R Gramlich, E Aliahmadi, M Peiser
    Int J Mol Sci, 2019;20(6):.
    Species: Human
    Sample Types: Cell Culture Supernates
  12. High expression of S100 calgranulin genes in peripheral blood mononuclear cells from patients with Takayasu arteritis
    Authors: J Kabeerdoss, M Thomas, R Goel, H Mohan, S Danda, J L, D Danda
    Cytokine, 2019;114(0):61-66.
    Species: Human
    Sample Types: Cell Culture Supernates
  13. The contraceptive medroxyprogesterone acetate, unlike norethisterone, directly increases R5 HIV-1 infection in human cervical explant tissue at physiologically relevant concentrations
    Authors: RM Ray, MF Maritz, C Avenant, M Tomasicchi, S Dlamini, Z van der Sp, JP Hapgood
    Sci Rep, 2019;9(1):4334.
    Species: Human
    Sample Types: Tissue Culture Supernates
  14. Engulfment, persistence and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential
    Authors: D Raghunatha, PM Radford, C Gell, D Negus, C Moore, R Till, PJ Tighe, SP Wheatley, L Martinez-P, RE Sockett, J Tyson
    Sci Rep, 2019;9(1):4293.
    Species: Human
    Sample Types: Cell Culture Supernates
  15. Regulation of radiosensitivity by 4-methylumbelliferone via the suppression of interleukin-1 in fibrosarcoma cells
    Authors: R Saga, K Hasegawa, K Murata, M Chiba, T Nakamura, K Okumura, E Tsuruga, Y Hosokawa
    Oncol Lett, 2019;17(3):3555-3561.
    Species: Human
    Sample Types: Cell Culture Supernates
  16. Resistance to lysosomotropic drugs used to treat kidney and breast cancers involves autophagy and inflammation and converges in inducing CXCL5
    Authors: S Giuliano, M Dufies, PD Ndiaye, J Viotti, D Borchielli, J Parola, V Vial, Y Cormerais, M Ohanna, V Imbert, E Chamorey, N Rioux-Lecl, A Savina, JM Ferrero, B Mograbi, G Pagès
    Theranostics, 2019;9(4):1181-1199.
    Species: Human
    Sample Types: Cell Culture Supernates
  17. Calcineurin inhibitors reduce NFAT-dependent expression of antifungal pentraxin-3 by human monocytes
    Authors: K Bendí?ková, F Tidu, M De Zuani, MH Kohoutková, I Andrej?ino, A Pompeiano, S B?lášková, G Forte, T Zelante, J Fri?
    J. Leukoc. Biol., 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  18. Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma
    Authors: EA Ebbing, AP van der Za, A Steins, A Creemers, S Hermsen, R Rentenaar, M Klein, C Waasdorp, GKJ Hooijer, SL Meijer, KK Krishnadat, CJA Punt, MI van Berge, SS Gisbertz, OM van Delden, MCCM Hulshof, JP Medema, HWM van Laarho, MF Bijlsma
    Proc. Natl. Acad. Sci. U.S.A., 2019;0(0):.
    Species: Human
    Sample Types: Serum
  19. Evolving understanding of cardiovascular, cerebrovascular and peripheral arterial disease in people living with HIV and role of novel biomarkers. A study of the Spanish CoRIS cohort, 2004-2015
    Authors: M Masiá, S Padilla, JA García, J García-Abe, M Fernández, I Bernardino, M Montero, J Peraire, B Pernas, F Gutiérrez
    PLoS ONE, 2019;14(4):e0215507.
    Species: Human
    Sample Types: Plasma
  20. Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis
    Authors: C Wei, C Yang, S Wang, D Shi, C Zhang, X Lin, Q Liu, R Dou, B Xiong
    Mol. Cancer, 2019;18(1):64.
    Species: Human
    Sample Types: Cell Culture Supernates
  21. Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice
    Authors: VB Lê, J Dubois, C Couture, MH Cavanagh, O Uyar, A Pizzorno, M Rosa-Calat, MÈ Hamelin, G Boivin
    PLoS Pathog., 2019;15(4):e1007689.
    Species: Human
    Sample Types: Cell Culture Supernates
  22. Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis
    Authors: MR Hadjichara, BT Roux, E Csomor, CA Feghali-Bo, LA Murray, DL Clarke, MA Lindsay
    Sci Rep, 2019;9(1):6020.
    Species: Human
    Sample Types: Cell Culture Supernates
  23. Systemic inflammation is associated with malaria and preterm birth in women living with HIV on antiretrovirals and co-trimoxazole
    Authors: CR McDonald, AM Weckman, AL Conroy, P Olwoch, P Natureeba, MR Kamya, DV Havlir, G Dorsey, KC Kain
    Sci Rep, 2019;9(1):6758.
    Species: Human
    Sample Types: Plasma
  24. Secondhand smoke exposure and sleep-related breathing problems in toddlers
    Authors: JA Groner, L Nicholson, H Huang, JA Bauer
    Acad Pediatr, 2019;0(0):.
    Species: Human
    Sample Types: Serum
  25. Circulating growth/differentiation factor 15 is associated with human CD56bright natural killer cell dysfunction and nosocomial infection in severe systemic inflammation
    Authors: H Kleinertz, M Hepner-Sch, S Ehnert, M Claus, R Halbgebaue, L Boller, M Huber-Lang, P Cinelli, C Kirschning, S Flohé, A Sander, C Waydhas, S Vonderhage, M Jäger, M Dudda, C Watzl, SB Flohé
    EBioMedicine, 2019;0(0):.
    Species: Human
    Sample Types: Serum
  26. 25(OH)D3 and 1.25(OH)2D3 inhibits TNF-? expression in human monocyte derived macrophages
    Authors: A Rafique, L Rejnmark, L Heickendor, HJ Møller
    PLoS ONE, 2019;14(4):e0215383.
    Species: Human
    Sample Types: Cell Culture Supernates
  27. The effect of compressive force combined with mechanical vibration on human alveolar bone osteoblasts
    Authors: C Chatmahamo, A Pravithara, S Suttapreya, C Leethanaku
    J Oral Biol Craniofac Res, 2019;9(1):81-85.
    Species: Human
    Sample Types: Cell Culture Supernates
  28. Genome wide analysis of TLR1/2- and TLR4-activated SZ95 sebocytes reveals a complex immune-competence and identifies serum amyloid A as a marker for activated sebaceous glands
    Authors: D Tör?csik, D Kovács, S Póliska, Z Szentkeres, M Lovászi, K Hegyi, A Szegedi, CC Zouboulis, M Ståhle
    PLoS ONE, 2018;13(6):e0198323.
    Species: Human
    Sample Types: Cell Culture Supernates
  29. IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis
    Authors: AC Gross, H Cam, DA Phelps, AJ Saraf, HK Bid, M Cam, CA London, SA Winget, MA Arnold, L Brandolini, X Mo, JM Hinckley, PJ Houghton, RD Roberts
    JCI Insight, 2018;3(16):.
    Species: Human
    Sample Types: Cell Culture Supernates
  30. The Effects of Varying Degree of MWCNT Carboxylation on Bioactivity in Various In Vivo and In Vitro Exposure Models
    Authors: RF Hamilton, Z Wu, S Mitra, A Holian
    Int J Mol Sci, 2018;19(2):.
    Species: Human
    Sample Types: Cell Culture Supernates
  31. Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression
    Authors: CC Wei, YJ Kung, CS Chen, CY Chang, CJ Lin, PT Tien, HY Chang, HJ Chen, YS Huang, HJ Lin, L Wan
    EBioMedicine, 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  32. Plasma inflammatory and immune proteins as predictors of intra-amniotic infection and spontaneous preterm delivery in women with preterm labor: a retrospective study
    Authors: H Park, KH Park, YM Kim, SY Kook, SJ Jeon, HN Yoo
    BMC Pregnancy Childbirth, 2018;18(1):146.
    Species: Human
    Sample Types: Amniotic Fluid
  33. Human cytomegalovirus replication induces endothelial cell interleukin-11
    Authors: KLR Gustafsson, T Renné, C Söderberg-, LM Butler
    Cytokine, 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  34. Effect of combined inhibition of p110 alpha PI3K isoform and STAT3 pathway in ovarian cancer platinum-based resistance
    Authors: A Le Naour, R Mevel, B Thibault, E Courtais, E Chantalat, JP Delord, B Couderc, J Guillermet, A Martinez
    Oncotarget, 2018;9(43):27220-27232.
    Species: Human
    Sample Types: Serum
  35. Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes
    Authors: J Lucifora, M Bonnin, L Aillot, F Fusil, S Maadadi, L Dimier, M Michelet, O Floriot, A Ollivier, M Rivoire, M Ait-Gougho, S Daffis, SP Fletcher, A Salvetti, FL Cosset, F Zoulim, D Durantel
    Sci Rep, 2018;8(1):5390.
    Species: Human
    Sample Types: Cell Culture Supernates
  36. Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis
    Authors: F Mizoguchi, K Slowikowsk, K Wei, JL Marshall, DA Rao, SK Chang, HN Nguyen, EH Noss, JD Turner, BE Earp, PE Blazar, J Wright, BP Simmons, LT Donlin, GD Kalliolias, SM Goodman, VP Bykerk, LB Ivashkiv, JA Lederer, N Hacohen, PA Nigrovic, A Filer, CD Buckley, S Raychaudhu, MB Brenner
    Nat Commun, 2018;9(1):789.
    Species: Human
    Sample Types: Cell Culture Supernates
  37. Anti-inflammatory activity of CKC-containing cationic emulsion eye drop vehicles
    Authors: P Daull, S Guenin, V Hamon de A, JS Garrigue
    Mol. Vis., 2018;24(0):459-470.
    Species: Human
    Sample Types: Cell Culture Supernates
  38. TiO2 nanoparticles can selectively bind CXCL8 impacting on neutrophil chemotaxis
    Authors: J Batt, M Milward, I Chapple, M Grant, H Roberts, O Addison
    Eur Cell Mater, 2018;35(0):13-24.
  39. iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE
    Authors: I Oikonomidi, E Burbridge, M Cavadas, G Sullivan, B Collis, H Naegele, D Clancy, J Brezinova, T Hu, A Bileck, C Gerner, A Bolado, A von Kriegs, SJ Martin, F Steinberg, K Strisovsky, C Adrain
    Elife, 2018;7(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  40. Broad adsorption of sepsis-related PAMP and DAMP molecules, mycotoxins, and cytokines from whole blood using CytoSorb� sorbent porous polymer beads
    Authors: MC Gruda, KG Ruggeberg, P O'Sullivan, T Guliashvil, AR Scheirer, TD Golobish, VJ Capponi, PP Chan
    PLoS ONE, 2018;13(1):e0191676.
    Species: Human
    Sample Types: Complex Sample Type
  41. Distinct Properties of Human M-CSF and GM-CSF Monocyte-Derived Macrophages to Simulate Pathological Lung Conditions In Vitro: Application to Systemic and Inflammatory Disorders with Pulmonary Involvement
    Authors: A Lescoat, A Ballerie, Y Augagneur, C Morzadec, L Vernhet, O Fardel, P Jégo, S Jouneau, V Lecureur
    Int J Mol Sci, 2018;19(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  42. Inhibition of Proteasome Activity Upregulates IL-6 Expression in RPE Cells through the Activation of P38 MAPKs
    Authors: T Qin, S Gao
    J Ophthalmol, 2018;2018(0):5392432.
    Species: Human
    Sample Types: Cell Culture Supernates
  43. CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma
    Authors: X Ye, X Wang, R Lu, J Zhang, X Chen, G Zhou
    Oncol Lett, 2018;15(6):9075-9080.
    Species: Human
    Sample Types: Cell Culture Supernates
  44. Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis
    Authors: R Narasimhan, R Coras, SB Rosenthal, SR Sweeney, A Lodi, S Tiziani, D Boyle, A Kavanaugh, M Guma
    Arthritis Res. Ther., 2018;20(1):164.
    Species: Human
    Sample Types: Serum
  45. Human Mesenchymal Stem Cell Secretome from Bone Marrow or Adipose-Derived Tissue Sources for Treatment of Hypoxia-Induced Pulmonary Epithelial Injury
    Authors: N Shologu, M Scully, JG Laffey, D O'Toole
    Int J Mol Sci, 2018;19(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  46. Effects of agricultural organic dusts on human lung-resident mesenchymal stem (stromal) cell function
    Authors: TM Nordgren, KL Bailey, AJ Heires, D Katafiasz, DJ Romberger
    Toxicol. Sci., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  47. A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults
    Authors: LBS Hansen, HM Roager, NB Søndertoft, RJ Gøbel, M Kristensen, M Vallès-Col, S Vieira-Sil, S Ibrügger, MV Lind, RB Mærkedahl, MI Bahl, ML Madsen, J Havelund, G Falony, I Tetens, T Nielsen, KH Allin, HL Frandsen, B Hartmann, JJ Holst, MH Sparholt, J Holck, A Blennow, JM Moll, AS Meyer, C Hoppe, JH Poulsen, V Carvalho, D Sagnelli, MD Dalgaard, AF Christense, MC Lydolph, AB Ross, S Villas-Bôa, S Brix, T Sicheritz-, K Buschard, A Linneberg, JJ Rumessen, CT Ekstrøm, C Ritz, K Kristianse, HB Nielsen, H Vestergaar, NJ Færgeman, J Raes, H Frøkiær, T Hansen, L Lauritzen, R Gupta, TR Licht, O Pedersen
    Nat Commun, 2018;9(1):4630.
    Species: Human
    Sample Types: Cell Culture Supernates
  48. Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer
    Authors: MH Kubala, V Punj, VR Placencio-, H Fang, GE Fernandez, R Sposto, YA DeClerck
    Cell Rep, 2018;25(8):2177-2191.e7.
    Species: Human
    Sample Types: Cell Culture Supernates
  49. A Transient Pseudosenescent Secretome Promotes Tumor Growth after Antiangiogenic Therapy Withdrawal
    Authors: M Mastri, A Tracz, CR Lee, M Dolan, K Attwood, JG Christense, S Liu, JML Ebos
    Cell Rep, 2018;25(13):3706-3720.e8.
    Species: Human
    Sample Types: Cell Culture Supernates
  50. Overproduction of IL-6 and Type-I IFN in a Lethal Case of Chikungunya Virus Infection in an Elderly Man During the 2017 Italian Outbreak
    Authors: F Colavita, S Vita, E Lalle, F Carletti, L Bordi, D Vincenti, I Pozzetto, M Aiuti, F Vairo, MR Capobianch, M Lichtner, C Castillett
    Open Forum Infect Dis, 2018;5(11):ofy276.
    Species: Human
    Sample Types: Plasma
  51. Crosstalk Between Nuclear Glucose-Regulated Protein 78 and Tumor Protein 53 Contributes to the Lipopolysaccharide Aggravated Apoptosis of Endoplasmic Reticulum Stress-Responsive Porcine Intestinal Epithelial Cells
    Authors: Q Jiang, G Liu, J Chen, K Yao, Y Yin
    Cell. Physiol. Biochem., 2018;48(6):2441-2455.
    Species: Porcine
    Sample Types: Cell Culture Supernates
  52. Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease
    Authors: S Yi, R Chang, J Hu, Y Qiu, Q Wang, Q Cao, G Yuan, G Su, C Zhou, Y Wang, A Kijlstra, P Yang
    Invest. Ophthalmol. Vis. Sci., 2018;59(11):4662-4669.
    Species: Human
    Sample Types: Cell Culture Supernates
  53. Electrophilic properties of itaconate and derivatives regulate the�I?B?-ATF3 inflammatory axis
    Authors: M Bambouskov, L Gorvel, V Lampropoul, A Sergushich, E Loginichev, K Johnson, D Korenfeld, ME Mathyer, H Kim, LH Huang, D Duncan, H Bregman, A Keskin, A Santeford, RS Apte, R Sehgal, B Johnson, GK Amarasingh, MP Soares, T Satoh, S Akira, T Hai, C de Guzman, K Auclair, TP Roddy, SA Biller, M Jovanovic, E Klechevsky, KM Stewart, GJ Randolph, MN Artyomov
    Nature, 2018;556(7702):501-504.
    Species: Human
    Sample Types: Cell Culture Supernates
  54. Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease
    Authors: Y Yue, J Zhang, L Yang, S Liu, J Qi, Q Cao, C Zhou, Y Wang, A Kijlstra, P Yang, S Hou
    Invest. Ophthalmol. Vis. Sci., 2018;59(2):1158-1166.
    Species: Human
    Sample Types: Cell Culture Supernates
  55. Annexin A1, FPR2/ALX, and inflammatory cytokine expression in peritoneal endometriosis
    Authors: LK Volpato, VV Horewicz, F Bobinski, DF Martins, AP Piovezan
    J. Reprod. Immunol., 2018;129(0):30-35.
    Species: Human
    Sample Types: Peritoneal Fluid
  56. Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
    Authors: SE Logue, EP McGrath, P Cleary, S Greene, K Mnich, A Almanza, E Chevet, RM Dwyer, A Oommen, P Legembre, F Godey, EC Madden, B Leuzzi, J Obacz, Q Zeng, JB Patterson, R Jäger, AM Gorman, A Samali
    Nat Commun, 2018;9(1):3267.
    Species: Human
    Sample Types: Cell Culture Supernates
  57. GWAS for Interleukin-1? levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation
    Authors: S Offenbache, Y Jiao, SJ Kim, J Marchesan, KL Moss, L Jing, K Divaris, S Bencharit, CS Agler, T Morelli, S Zhang, L Sun, WT Seaman, D Cowley, SP Barros, JD Beck, M Munz, AS Schaefer, KE North
    Nat Commun, 2018;9(1):3686.
    Species: Human
    Sample Types: Cell Culture Supernates
  58. Minocycline modulates NF?B phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells
    Authors: AD Guerra, WE Rose, P Hematti, WJ Kao
    Stem Cell Res Ther, 2017;8(1):171.
    Species: Human
    Sample Types: Cell Culture Supernates
  59. Increased expression of Siglec-9 in chronic obstructive pulmonary disease
    Authors: Z Zeng, M Li, M Wang, X Wu, Q Li, Q Ning, J Zhao, Y Xu, J Xie
    Sci Rep, 2017;7(1):10116.
    Species: Human
    Sample Types: Cell Culture Supernates
  60. Pre- and post-surgical evaluation of the inflammatory response in patients with aortic stenosis treated with different types of prosthesis
    Authors: ME Soto, JL Salas, J Vargas-Bar, R Marquez, A Rodriguez-, R Bojalil-Pa, I Pérez-Torr, V Guarner-La
    BMC Cardiovasc Disord, 2017;17(1):100.
    Species: Human
    Sample Types: Serum
  61. cfDNA correlates with endothelial damage after cardiac surgery with prolonged cardiopulmonary bypass and amplifies NETosis in an intracellular TLR9-independent manner
    Authors: A Paunel-Gör, M Wacker, M El Aita, S Hassan, G Schlachten, A Deppe, YH Choi, E Kuhn, TO Mehler, T Wahlers
    Sci Rep, 2017;7(1):17421.
    Species: Human
    Sample Types: Plasma
  62. Human gestation-associated tissues express functional cytosolic nucleic acid sensing pattern recognition receptors
    Authors: AH Bryant, GE Menzies, LM Scott, S Spencer-Ha, LB Davies, RA Smith, RH Jones, CA Thornton
    Clin. Exp. Immunol, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  63. Pathogenic role of glycan-specific IgG antibodies in IgA nephropathy
    Authors: YF Zhao, L Zhu, LJ Liu, SF Shi, JC Lv, H Zhang
    BMC Nephrol, 2017;18(1):301.
    Species: Human
    Sample Types: Cell Culture Supernates
  64. Frequency and clinical significance of short cervix in patients with preterm premature rupture of membranes
    Authors: SM Lee, KH Park, EY Jung, JA Jang, HN Yoo
    PLoS ONE, 2017;12(3):e0174657.
    Species: Human
    Sample Types: Amniotic Fluid
  65. Cutting Edge: Genetic Association between IFI16 Single Nucleotide Polymorphisms and Resistance to Genital Herpes Correlates with IFI16 Expression Levels and HSV-2-Induced IFN-? Expression
    Authors: K Eriksson, A Svensson, AS Hait, K Schlüter, P Tunbäck, I Nordström, L Padyukov, JÅ Liljeqvist, TH Mogensen, SR Paludan
    J. Immunol., 2017;0(0):.
    Species: Human
    Sample Types: Plasma
  66. Tumor-Derived Mesenchymal Stem Cells Use Distinct Mechanisms to Block the Activity of Natural Killer Cell Subsets
    Authors: S Galland, J Vuille, P Martin, I Letovanec, A Caignard, G Fregni, I Stamenkovi
    Cell Rep, 2017;20(12):2891-2905.
    Species: Human
    Sample Types: Cell Culture Supernates
  67. Expression of MicroRNA in Host Cells Infected with Helicobacter pylori
    Authors: JW Chung, SH Jeong, SM Lee, JH Pak, GH Lee, JY Jeong, JH Kim
    Gut Liver, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  68. Presence of IL-17 in synovial fluid identifies a potential inflammatory osteoarthritic phenotype
    Authors: SJ Snelling, S Bas, GJ Puskas, SG Dakin, D Suva, A Finckh, C Gabay, P Hoffmeyer, AJ Carr, A Lübbeke
    PLoS ONE, 2017;12(4):e0175109.
    Species: Human
    Sample Types: Serum
  69. Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide
    Authors: L Chen, MS Eapen, GR Zosky
    Sci Rep, 2017;7(0):45172.
    Species: Human
    Sample Types: Cell Culture Supernates
  70. Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory FADDosome Complex upon TRAIL Stimulation
    Authors: CM Henry, SJ Martin
    Mol. Cell, 2017;65(4):715-729.e5.
    Species: Human
    Sample Types: Cell Culture Supernates
  71. Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways
    Authors: A Burban, A Sharanek, R Hüe, M Gay, S Routier, A Guillouzo, C Guguen-Gui
    Sci Rep, 2017;7(1):1815.
    Species: Human
    Sample Types: Cell Culture Supernates
  72. IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesity
    Authors: MJ Pearson, D Herndler-B, MA Tariq, TA Nicholson, AM Philp, HL Smith, ET Davis, SW Jones, JM Lord
    Sci Rep, 2017;7(1):3451.
    Species: Human
    Sample Types: Cell Culture Supernates
  73. Advances in the quantification of mitochondrial function in primary human immune cells through extracellular flux analysis
    Authors: D Nicholas, EA Proctor, FM Raval, BC Ip, C Habib, E Ritou, TN Grammatopo, D Steenkamp, H Dooms, CM Apovian, DA Lauffenbur, BS Nikolajczy
    PLoS ONE, 2017;12(2):e0170975.
    Species: Human
    Sample Types: Cell Culture Supernates
  74. Improvement of cardiometabolic markers after fish oil intervention in young Mexican adults and the role of PPAR? L162V and PPAR?2 P12A
    Authors: A Binia, C Vargas-Mar, M Ancira-Mor, LM Gosoniu, I Montoliu, E Gámez-Vald, DC Soria-Cont, A Angeles-Qu, R Gonzalez-A, S Fernández, D Martínez-C, B Hernández-, M Ramírez-So, C Pérez-Orte, Y Rodríguez-, I Castan, I Rubio-Alia, F Vadillo-Or, R Márquez-Ve, R Bojalil, JC López-Alva, P Valet, M Kussmann, I Silva-Zole, ME Tejero
    J. Nutr. Biochem., 2017;43(0):98-106.
    Species: Human
    Sample Types: Serum
  75. Resistin as a Prooxidant Factor and Predictor of Endothelium Damage in Patients with Mild Acute Pancreatitis Exposed to Tobacco Smoke Xenobiotics
    Authors: M ?ciskalska, G Marek, Z Grzebienia, H Milnerowic
    Mediators Inflamm., 2017;2017(0):3039765.
    Species: Human
    Sample Types: Plasma
  76. Associations between TNFSF4, TNFSF8 and TNFSF15 and Beh�et's disease but not VKH syndrome in Han Chinese
    Authors: Y Jiang, L Cheng, X Li, W Zhou, L Zhang
    Oncotarget, 2017;8(62):105037-105046.
    Species: Human
    Sample Types: Cell Culture Supernates
  77. Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study
    Authors: KS van der Ge, Q Wang, TM Eijsvogels, HJ Koenen, I Joosten, E Brouwer, MT Hopman, JF Jacobs, AM Boots
    Immun Ageing, 2017;14(0):5.
    Species: Human
    Sample Types: Cell Culture Supernates
  78. Allostimulatory capacity of conditionally immortalized proximal tubule cell lines for bioartificial kidney application
    Authors: M Mihajlovic, LP van den He, JG Hoenderop, J Jansen, MJ Wilmer, AJF Westheim, WA Allebes, D Stamatiali, LB Hilbrands, R Masereeuw
    Sci Rep, 2017;7(1):7103.
    Species: Human
    Sample Types: Cell Culture Supernates
  79. Iron nanomedicines induce Toll-like receptor activation, cytokine production and complement activation
    Authors: Johan J F Verhoef
    Biomaterials, 2017;119(0):68-77.
    Species: Human
    Sample Types: Cell Culture Supernates
  80. Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease
    Authors: J Ikari, AJ Nelson, J Obaid, A Giron-Mart, K Ikari, F Makino, S Iwasawa, Y Gunji, M Farid, X Wang, H Basma, D Demeo, C Feghali-Bo, O Holz, K Rabe, X Liu, SI Rennard
    PLoS ONE, 2017;12(9):e0184039.
    Species: Human
    Sample Types: Cell Culture Supernates
  81. Demyelination induced by oxidative stress is regulated by sphingosine 1-phosphate receptors
    Authors: SA O'Sullivan, M Velasco-Es, KK Dev
    Glia, 2017;0(0):.
  82. Prevention of influenza virus induced bacterial superinfection by standardized Echinacea purpurea, via regulation of surface receptor expression in human bronchial epithelial cells
    Authors: V Selvarani, S Roland, S Andy, H James
    Virus Res, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  83. Collagen-Based Medical Device as a Stem Cell Carrier for Regenerative Medicine
    Authors: L Aubert, M Dubus, H Rammal, C Bour, C Mongaret, C Boulagnon-, R Garnotel, C Schneider, R Rahouadj, C Laurent, SC Gangloff, F Velard, C Mauprivez, H Kerdjoudj
    Int J Mol Sci, 2017;18(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  84. In vitro and in vivo antagonistic activity of new probiotic culture against Clostridium difficile and Clostridium perfringens
    Authors: N Goli?, K Veljovi?, N Popovi?, J Djoki?, I Strahini?, I Mrvaljevi?, A Terzi?-Vid
    BMC Microbiol., 2017;17(1):108.
    Species: Human
    Sample Types: Cell Culture Supernates
  85. Adipogenic differentiation of MSC alters their immunomodulatory properties in a tissue-specific manner
    Authors: H Munir, LS Ward, L Sheriff, S Kemble, S Nayar, F Barone, GB Nash, HM McGettrick
    Stem Cells, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  86. Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model
    Authors: TJJ Schirris, J Jansen, M Mihajlovic, LP van den He, R Masereeuw, FGM Russel
    Sci Rep, 2017;7(1):10623.
    Species: Human
    Sample Types: Cell Culture Supernates
  87. Amniotic Fluid Infection, Cytokine Levels, and Mortality and Adverse Pulmonary, Intestinal, and Neurologic Outcomes in Infants at 32 Weeks' Gestation or Less
    Authors: EY Jung, KH Park, BR Han, SH Cho, HN Yoo, J Lee
    J. Korean Med. Sci, 2017;32(3):480-487.
    Species: Human
    Sample Types: Amniotic Fluid
  88. MicroRNA-143 and -145 modulate the phenotype of synovial fibroblasts in rheumatoid arthritis
    Authors: BK Hong, S You, SA Yoo, D Park, D Hwang, CS Cho, WU Kim
    Exp. Mol. Med., 2017;49(8):e363.
    Species: Human
    Sample Types: Cell Culture Supernates
  89. Clinical significance of histologic chorioamnionitis with a negative amniotic fluid culture in patients with preterm labor and premature membrane rupture
    Authors: JW Park, KH Park, EY Jung
    PLoS ONE, 2017;12(3):e0173312.
    Species: Human
    Sample Types: Amniotic Fluid
  90. Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative Function
    Authors: RM Petri, A Hackel, K Hahnel, CA Dumitru, K Bruderek, SB Flohe, A Paschen, S Lang, S Brandau
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  91. Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4
    Authors: M Du, A Martin, F Hays, J Johnson, RA Farjo, KM Farjo
    Mol. Vis., 2017;23(0):185-197.
    Species: Human
    Sample Types: Cell Culture Supernates
  92. Role of Vitamin D in Maintaining Renal Epithelial Barrier Function in Uremic Conditions
    Authors: M Mihajlovic, M Fedecostan, MJ Oost, SKP Steenhuis, EGWM Lentjes, I Maitimu-Sm, MJ Janssen, LB Hilbrands, R Masereeuw
    Int J Mol Sci, 2017;18(12):.
    Species: Human
    Sample Types: Cell Culture Supernates
  93. The Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Cellular Senescence of Cultivated Human Corneal Endothelial Cells
    Authors: A Hongo, N Okumura, M Nakahara, EP Kay, N Koizumi
    Invest. Ophthalmol. Vis. Sci., 2017;58(9):3325-3334.
    Species: Human
    Sample Types: Cell Culture Supernates
  94. Therapeutic effect of a novel histone deacetylase 6 inhibitor, CKD-L, on collagen-induced arthritis in vivo and regulatory T cells in rheumatoid arthritis in vitro
    Authors: BR Oh, DH Suh, D Bae, N Ha, YI Choi, HJ Yoo, JK Park, EY Lee, EB Lee, YW Song
    Arthritis Res. Ther., 2017;19(1):154.
    Species: Human
    Sample Types: Cell Culture Supernates
  95. Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-?B acivation
    Authors: Sofia Avnet
    Int. J. Cancer, 2016;0(0):.
    Species: Human
    Sample Types: Serum
  96. MODELING STROMA-INDUCED DRUG RESISTANCE IN A TISSUE-ENGINEERED TUMOR MODEL OF EWING SARCOMA
    Authors: Marco Santoro
    Tissue Eng Part A, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  97. Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion
    PLoS ONE, 2016;11(11):e0166500.
    Species: Human
    Sample Types: Cell Culture Supernates
  98. Hepcidin-Induced Iron Deficiency Is Related to Transient Anemia and Hypoferremia in Kawasaki Disease Patients
    Int J Mol Sci, 2016;17(5):.
    Species: Human
    Sample Types: Plasma
  99. Engineering a 3D microfluidic culture platform for tumor-treating field application
    Sci Rep, 2016;6(0):26584.
    Species: Human
    Sample Types: Cell Culture Supernates
  100. Amyloid precursor protein mediated changes in intestinal epithelial phenotype in vitro.
    Authors: Puig K, Manocha G, Combs C
    PLoS ONE, 2016;10(3):e0119534.
    Species: Human
    Sample Types: Cell Culture Supernates
  101. Acanthamoeba castellanii (Genotype T4) Stimulates the Production of Interleukin-10 as well as Pro-inflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells and Human Monocyte-Derived Macrophages
    Infect Immun, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  102. CD36-Mediated Uptake of Surfactant Lipids by Human Macrophages Promotes Intracellular Growth of Mycobacterium tuberculosis
    J. Immunol., 2016;197(12):4727-4735.
    Species: Human
    Sample Types: Cell Culture Supernates
  103. Nitro-Oleic Acid Prevents Hypoxia- and Asymmetric Dimethylarginine-Induced Pulmonary Endothelial Dysfunction
    Authors: Michaela Pekarova
    Cardiovasc Drugs Ther, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  104. Graphene-augmented nanofiber scaffolds demonstrate new features in cells behaviour
    Sci Rep, 2016;6(0):30150.
    Species: Human
    Sample Types: Cell Culture Supernates
  105. Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability
    Sci Rep, 2016;6(0):39035.
    Species: Human
    Sample Types: Cell Culture Supernates
  106. Genetic polymorphisms of cell adhesion molecules in Behcet's disease in a Chinese Han population
    Authors: M Zheng, L Zhang, H Yu, J Hu, Q Cao, G Huang, Y Huang, G Yuan, A Kijlstra, P Yang
    Sci Rep, 2016;6(0):24974.
    Species: Human
    Sample Types: Cell Culture Supernates
  107. Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Beh�et's disease
    Sci Rep, 2016;6(0):26662.
    Species: Human
    Sample Types: Cell Culture Supernates
  108. Essential Oils from Ugandan Medicinal Plants: In Vitro Cytotoxicity and Effects on IL-1?-Induced Proinflammatory Mediators by Human Gingival Fibroblasts
    Evid Based Complement Alternat Med, 2016;2016(0):5357689.
    Species: Human
    Sample Types: Cell Culture Supernates
  109. Stand-Sit Microchip for High-Throughput, Multiplexed Analysis of Single Cancer Cells
    Sci Rep, 2016;6(0):32505.
    Applications: ChIP
  110. Comparative Ability of Mesenchymal Stromal Cells from Different Tissues to Limit Neutrophil Recruitment to Inflamed Endothelium
    PLoS ONE, 2016;11(5):e0155161.
    Species: Human
    Sample Types: Cell Culture Supernates
  111. Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells
    Authors: S Robert, T Gicquel, A Bodin, V Lagente, E Boichot
    PLoS ONE, 2016;11(4):e0153118.
    Species: Human
    Sample Types: Cell Culture Supernates
  112. Dual Inhibition of Rip2 and IRAK1/4 Regulates IL-1? and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear Cells
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  113. IL-17 Promotes Neutrophil-Mediated Immunity by Activating Microvascular Pericytes and Not Endothelium
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  114. Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion
    Authors: Mélissa Noack
    Arthritis Res Ther, 2016;18(0):148.
    Species: Human
    Sample Types: Cell Culture Supernates
  115. Modulating endotoxin activity by combinatorial bioengineering of meningococcal lipopolysaccharide
    Sci Rep, 2016;6(0):36575.
    Species: Human
    Sample Types: Cell Culture Supernates
  116. Altered Systemic Adipokines in Patients with Chronic Urticaria
    Authors: Hoang Kim Tu Trinh
    Int. Arch. Allergy Immunol, 2016;171(2):102-110.
    Species: Human
    Sample Types: Serum
  117. DNA Sensing via TLR-9 Constitutes a Major Innate Immunity Pathway Activated during Erythema Nodosum Leprosum
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  118. Serum from Varicose Patients Induces Senescence-Related Dysfunction of Vascular Endothelium Generating Local and Systemic Proinflammatory Conditions
    Oxid Med Cell Longev, 2016;2016(0):2069290.
    Species: Human
    Sample Types: Serum
  119. Temperature responsive porous silicon nanoparticles for cancer therapy - spatiotemporal triggering through infrared and radiofrequency electromagnetic heating
    J Control Release, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  120. Biocompatibility of primers and an adhesive used for implant-retained maxillofacial prostheses: An in�vitro analysis
    Authors: Daniela Micheline Dos Santos
    J Prosthet Dent, 2016;0(0):.
  121. Novel approach to study the cardiovascular effects and mechanism of action of urban particulate matter using lung epithelial-endothelial tetra-culture system
    Authors: Kyu Hyuck Chung
    Toxicol In Vitro, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  122. Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-?
    Aging Cell, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  123. Mitochondrial proteins NIP-SNAP-1 and -2 are a target for the immunomodulatory activity of clarithromycin, which involves NF-?B-mediated cytokine production
    Authors: Soh Yamamoto
    Biochem. Biophys. Res. Commun, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  124. Intracellular RIG-I Signaling Regulates TLR4-Independent Endothelial Inflammatory Responses to Endotoxin
    J Immunol, 2016;196(11):4681-91.
    Species: Human
    Sample Types: Cell Culture Supernates
  125. Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.
    Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S
    Cell Death Differ, 2015;22(8):1313-27.
    Species: Human
    Sample Types: Cell Culture Supernates
  126. BET bromodomains regulate transforming growth factor-beta-induced proliferation and cytokine release in asthmatic airway smooth muscle.
    Authors: Perry M, Durham A, Austin P, Adcock I, Chung K
    J Biol Chem, 2015;290(14):9111-21.
    Species: Human
    Sample Types: Cell Culture Supernates
  127. An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells.
    Authors: Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, Ghigo D, Riganti C
    PLoS ONE, 2015;10(5):e0126159.
    Species: Human
    Sample Types: Cell Culture Supernates
  128. Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2.
    Authors: Jaguin M, Fardel O, Lecureur V
    PLoS ONE, 2015;10(2):e0116560.
    Species: Human
    Sample Types: Cell Culture Supernates
  129. Effect of lipopolysaccharide on glucocorticoid receptor function in control nasal mucosa fibroblasts and in fibroblasts from patients with chronic rhinosinusitis with nasal polyps and asthma.
    Authors: Fernandez-Bertolin L, Mullol J, Fuentes-Prado M, Roca-Ferrer J, Alobid I, Picado C, Pujols L
    PLoS ONE, 2015;10(5):e0125443.
    Species: Human
    Sample Types: Cell Culture Supernates
  130. SRSF1 facilitates cytosolic DNA-induced production of type I interferons recognized by RIG-I.
    Authors: Xue F, Li X, Zhao X, Wang L, Liu M, Shi R, Zheng J
    PLoS ONE, 2015;10(2):e0115354.
    Species: Human
    Sample Types: Cell Culture Supernates
  131. LPS-Stimulated Whole Blood Cytokine Production Is Not Related to Disease Behavior in Patients with Quiescent Crohn's Disease.
    Authors: Broekman M, Roelofs H, Hoentjen F, Wiegertjes R, Stoel N, Joosten L, de Jong D, Wanten G
    PLoS ONE, 2015;10(7):e0133932.
    Species: Human
    Sample Types: Plasma
  132. The effects of knockdown of rho-associated kinase 1 and zipper-interacting protein kinase on gene expression and function in cultured human arterial smooth muscle cells.
    Authors: Deng J, Wang X, Chen Y, O'Brien E, Gui Y, Walsh M
    PLoS ONE, 2015;10(2):e0116969.
    Species: Human
    Sample Types: Cell Culture Supernates
  133. Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells.
    Authors: Price L, Shao D, Meng C, Perros F, Garfield B, Zhu J, Montani D, Dorfmuller P, Humbert M, Adcock I, Wort S
    Respir Res, 2015;16(0):114.
    Species: Human
    Sample Types: Cell Culture Supernates
  134. Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M.
    Authors: Kwofie K, Scott M, Rodrigues R, Guerette J, Radford K, Nair P, Richards C
    Respir Res, 2015;16(0):14.
    Species: Human
    Sample Types: Cell Culture Supernates
  135. High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus.
    Authors: Scheuplein V, Seifried J, Malczyk A, Miller L, Hocker L, Vergara-Alert J, Dolnik O, Zielecki F, Becker B, Spreitzer I, Konig R, Becker S, Waibler Z, Muhlebach M
    J Virol, 2015;89(7):3859-69.
    Species: Human
    Sample Types: Cell Culture Supernates
  136. Transcriptomic Analyses of the Biological Effects of Airborne PM2.5 Exposure on Human Bronchial Epithelial Cells.
    Authors: Zhou Z, Liu Y, Duan F, Qin M, Wu F, Sheng W, Yang L, Liu J, He K
    PLoS ONE, 2015;10(9):e0138267.
    Species: Human
    Sample Types: Cell Culture Supernates
  137. In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1beta, TNFalpha, IL-6, IL-8, IL-10, MIP-1alpha, and MMP-9 in pre-labor human term placenta.
    Authors: Garcia-Ruiz G, Flores-Espinosa P, Preciado-Martinez E, Bermejo-Martinez L, Espejel-Nunez A, Estrada-Gutierrez G, Maida-Claros R, Flores-Pliego A, Zaga-Clavellina V
    Reprod Biol Endocrinol, 2015;13(0):115.
    Species: Human
    Sample Types: Cell Culture Supernates
  138. Interleukin-23 Receptor Gene Polymorphism May Enhance Expression of the IL-23 Receptor, IL-17, TNF-alpha and IL-6 in Behcet's Disease.
    Authors: Jiang Z, Hennein L, Tao Y, Tao L
    PLoS ONE, 2015;10(7):e0134632.
    Species: Human
    Sample Types: Cell Culture Supernates
  139. Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes.
    Authors: Sommerfelt R, Feuerherm A, Skuland T, Johansen B
    PLoS ONE, 2015;10(4):e0119088.
    Species: Human
    Sample Types: Cell Culture Supernates
  140. A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis.
    Authors: Zhang Q, Qi J, Hou S, DU L, Yu H, Cao Q, Zhou Y, Liao D, Kijlstra A, Yang P
    PLoS ONE, 2014;9(5):e96943.
    Species: Human
    Sample Types: Cell Culture Supernates
  141. TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells.
    Authors: Liu B, Cao Y, Huizinga T, Hafler D, Toes R
    Eur J Immunol, 2014;44(7):2121-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  142. Role of non-coding RNAs in maintaining primary airway smooth muscle cells.
    Authors: Perry, Mark M, Tsitsiou, Eleni, Austin, Philip J, Lindsay, Mark A, Gibeon, David S, Adcock, Ian M, Chung, Kian Fan
    Respir Res, 2014;15(0):58.
    Species: Human
    Sample Types: Cell Culture Supernates
  143. Anti-inflammatory effects of green soybean extract irradiated with visible light.
    Authors: Tanaka K, Ohgo Y, Katayanagi Y, Yasui K, Hiramoto S, Ikemoto H, Nakata Y, Miyoshi N, Isemura M, Ohashi N, Imai S
    Sci Rep, 2014;4(0):4732.
    Species: Human
    Sample Types: Cell Culture Supernates
  144. Neisseria gonorrhoeae modulates iron-limiting innate immune defenses in macrophages.
    Authors: Zughaier, Susu M, Kandler, Justin L, Shafer, William
    PLoS ONE, 2014;9(1):e87688.
    Species: Human
    Sample Types: Cell Culture Supernates
  145. Optofluidic laser for dual-mode sensitive biomolecular detection with a large dynamic range.
    Authors: Wu X, Oo M, Reddy K, Chen Q, Sun Y, Fan X
    Nat Commun, 2014;5(0):3779.
    Species: Human
    Sample Types: Protein
  146. Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.
    Authors: Lin F, Hsiao F, Huang C, Shih C, Tsao N, Tsai C, Yang S, Chang N, Hung S, Lin Y
    PLoS ONE, 2014;9(7):e102450.
    Species: Human
    Sample Types: Cell Culture Supernates
  147. Bacterial siderophores that evade or overwhelm lipocalin 2 induce hypoxia inducible factor 1alpha and proinflammatory cytokine secretion in cultured respiratory epithelial cells.
    Authors: Holden V, Lenio S, Kuick R, Ramakrishnan S, Shah Y, Bachman M
    Infect Immun, 2014;82(9):3826-36.
    Species: Human
    Sample Types: Cell Culture Supernates
  148. Mycobacterium tuberculosis impairs dendritic cell functions through the serine hydrolase Hip1.
    Authors: Madan-Lala R, Sia J, King R, Adekambi T, Monin L, Khader S, Pulendran B, Rengarajan J
    J Immunol, 2014;192(9):4263-72.
    Species: Human
    Sample Types: Cell Culture Supernates
  149. Circulating autoantibodies to endothelial progenitor cells: binding characteristics and association with risk factors for atherosclerosis.
    Authors: George J, Matucci-Cerinic M, Bar I, Shimoni S
    PLoS ONE, 2014;9(6):e97836.
    Species: Human
    Sample Types: Serum
  150. Activin A as a mediator of NK-dendritic cell functional interactions.
    Authors: Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, Sozzani S
    J Immunol, 2014;192(3):1241-8.
    Species: Human
    Sample Types: Whole Cells
  151. RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.
    Authors: Rigby R, Webb L, Mackenzie K, Li Y, Leitch A, Reijns M, Lundie R, Revuelta A, Davidson D, Diebold S, Modis Y, MacDonald A, Jackson A
    EMBO J, 2014;33(6):542-58.
    Species: Human
    Sample Types: Cell Culture Supernates
  152. TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behcet's disease and Vogt-Koyanagi-Harada syndrome: a case-control study.
    Authors: Xiang Q, Chen L, Hou S, Fang J, Zhou Y, Bai L, Liu Y, Kijlstra A, Yang P
    PLoS ONE, 2014;9(1):e84214.
    Species: Human
    Sample Types: Cell Culture Supernates
  153. Lipopolysaccharide promotes contraction of uterine myocytes via activation of Rho/ROCK signaling pathways.
    Authors: Hutchinson J, Rajagopal S, Yuan M, Norman J
    FASEB J, 2014;28(1):94-105.
    Species: Human
    Sample Types: Cell Culture Supernates
  154. IL-17A RNA aptamer: possible therapeutic potential in some cells, more than we bargained for in others?
    Authors: Doble, Rosella, McDermott, Michael, Cesur, Ozlem, Stonehouse, Nicola J, Wittmann, Miriam
    J Invest Dermatol, 2014;134(3):852-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  155. Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition.
    Authors: Mimura N, Hideshima T, Shimomura T, Suzuki R, Ohguchi H, Rizq O, Kikuchi S, Yoshida Y, Cottini F, Jakubikova J, Cirstea D, Gorgun G, Minami J, Tai Y, Richardson P, Utsugi T, Iwama A, Anderson K
    Cancer Res, 2014;74(16):4458-69.
    Species: Human
    Sample Types: Cell Culture Supernates
  156. Engagement of SLAMF2/CD48 prolongs the time frame of effective T cell activation by supporting mature dendritic cell survival.
    Authors: Kis-Toth K, Tsokos G
    J Immunol, 2014;192(9):4436-42.
    Species: Human
    Sample Types: Cell Culture Supernates
  157. Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
    Authors: Dreymueller D, Martin C, Schumacher J, Groth E, Boehm J, Reiss L, Uhlig S, Ludwig A
    J Immunol, 2014;192(2):722-31.
    Species: Human
    Sample Types: Cell Culture Supernates
  158. Roles for the mitogen-activated protein kinase (MAPK) phosphatase, DUSP1, in feedback control of inflammatory gene expression and repression by dexamethasone.
    Authors: Shah S, King E, Chandrasekhar A, Newton R
    J Biol Chem, 2014;289(19):13667-79.
    Species: Human
    Sample Types: Cell Culture Supernates
  159. Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses.
    Authors: Hanuszkiewicz A, Pittock P, Humphries F, Moll H, Rosales A, Molinaro A, Moynagh P, Lajoie G, Valvano M
    J Biol Chem, 2014;289(27):19231-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  160. Inflammatory and cytotoxic effects of acrolein, nicotine, acetylaldehyde and cigarette smoke extract on human nasal epithelial cells.
    Authors: Comer D, Elborn J, Ennis M
    BMC Pulm Med, 2014;14(0):32.
    Species: Human
    Sample Types: Cell Culture Supernates
  161. Immunoepidemiological profiling of onchocerciasis patients reveals associations with microfilaria loads and ivermectin intake on both individual and community levels.
    Authors: Arndts, Kathrin, Specht, Sabine, Debrah, Alexande, Tamarozzi, Francesc, Klarmann Schulz, Ute, Mand, Sabine, Batsa, Linda, Kwarteng, Alexande, Taylor, Mark, Adjei, Ohene, Martin, Coralie, Layland, Laura E, Hoerauf, Achim
    PLoS Negl Trop Dis, 2014;8(2):e2679.
    Species: Human
    Sample Types: Cell Culture Supernates
  162. S100A12 suppresses pro-inflammatory, but not pro-thrombotic functions of serum amyloid A.
    Authors: Chung Y, Goyette J, Tedla N, Hsu K, Geczy C
    PLoS ONE, 2013;8(4):e62372.
  163. Decidual natural killer cell interactions with trophoblasts are impaired in pregnancies at increased risk of preeclampsia.
    Authors: Wallace A, Host A, Whitley G, Cartwright J
    Am J Pathol, 2013;183(6):1853-61.
    Species: Human
    Sample Types: Cell Culture Supernates
  164. Opposite cytokine synthesis by fibroblasts in contact co-culture with osteosarcoma cells compared with transwell co-cultures.
    Authors: David M, Kelly E, Zoellner H
    Cytokine, 2013;62(1):48-51.
    Species: Human
    Sample Types: Cell Culture Supernates
  165. Effects of high-dose cholecalciferol on serum markers of inflammation and immunity in patients with early chronic kidney disease.
    Authors: Alvarez J, Zughaier S, Law J, Hao L, Wasse H, Ziegler T, Tangpricha V
    Eur J Clin Nutr, 2013;67(3):264-9.
    Species: Human
    Sample Types: Serum
  166. Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling.
    Authors: Moh M, Lorenzini P, Gullo C, Schwarz H
    FASEB J, 2013;27(8):2957-66.
    Species: Human
    Sample Types: Cell Culture Supernates
  167. Human cytomegalovirus induces a biphasic inflammatory response in primary endothelial cells.
    Authors: Jeffery H, Soderberg-Naucler C, Butler L
    J Virol, 2013;87(11):6530-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  168. 1,25-dihydroxyvitamin D3 protects against macrophage-induced activation of NFkappaB and MAPK signalling and chemokine release in human adipocytes.
    Authors: Ding C, Wilding J, Bing C
    PLoS ONE, 2013;8(4):e61707.
    Species: Human
    Sample Types: Cell Culture Supernates
  169. Association of TLR2 gene polymorphisms with ocular Behcet's disease in a Chinese Han population.
    Authors: Fang J, Hu R, Hou S, Ye Z, Xiang Q, Qi J, Zhou Y, Kijlstra A, Yang P
    Invest Ophthalmol Vis Sci, 2013;54(13):8384-92.
    Species: Human
    Sample Types: Cell Culture Supernates
  170. Leptin enhances the secretion of interleukin (IL)-18, but not IL-1beta, from human monocytes via activation of caspase-1.
    Authors: Jitprasertwong P, Jaedicke K, Nile C, Preshaw P, Taylor J
    Cytokine, 2013;65(2):222-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  171. Tetra- and penta-acylated lipid A structures of Porphyromonas gingivalis LPS differentially activate TLR4-mediated NF-kappaB signal transduction cascade and immuno-inflammatory response in human gingival fibroblasts.
    Authors: Herath T, Darveau R, Seneviratne C, Wang C, Wang Y, Jin L
    PLoS ONE, 2013;8(3):e58496.
    Species: Human
    Sample Types: Cell Culture Supernates
  172. Quiescent innate response to infective filariae by human Langerhans cells suggests a strategy of immune evasion.
    Authors: Boyd A, Bennuru S, Wang Y, Sanprasert V, Law M, Chaussabel D, Nutman T, Semnani R
    Infect Immun, 2013;81(5):1420-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  173. Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system.
    Authors: Punsmann S, Liebers V, Lotz A, Bruning T, Raulf M
    PLoS ONE, 2013;8(12):e82734.
    Species: Human
    Sample Types: Serum
  174. Selective activation of human dendritic cells by OM-85 through a NF-kB and MAPK dependent pathway.
    Authors: Parola C, Salogni L, Vaira X, Scutera S, Somma P, Salvi V, Musso T, Tabbia G, Bardessono M, Pasquali C, Mantovani A, Sozzani S, Bosisio D
    PLoS ONE, 2013;8(12):e82867.
    Species: Human
    Sample Types: Cell Culture Supernates
  175. Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.
    Authors: Berthelot L, Papista C, Maciel TT, Biarnes-Pelicot M, Tissandie E, Wang PH, Tamouza H, Jamin A, Bex-Coudrat J, Gestin A, Boumediene A, Arcos-Fajardo M, England P, Pillebout E, Walker F, Daugas E, Vrtosvnik F, Flamant M, Benhamou M, Cogne M, Moura IC, Monteiro RC
    J. Exp. Med., 2012;209(4):793-806.
    Species: Human
    Sample Types: Cell Culture Supernates
  176. IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.
    Authors: van de Veerdonk FL, Stoeckman AK, Wu G, Boeckermann AN, Azam T, Netea MG, Joosten LA, Van der Meer JW, Hao R, Kalabokis V, Dinarello CA
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(8):3001-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  177. Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
    Authors: Suh HS, Choi N, Tarassishin L, Lee SC
    PLoS ONE, 2012;7(4):e35115.
    Species: Human
    Sample Types: Cell Culture Supernates
  178. Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
    Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
    PLoS ONE, 2012;7(4):e34965.
    Species: Human
    Sample Types: Cell Culture Supernates
  179. Trappin-2/elafin modulate innate immune responses of human endometrial epithelial cells to PolyI:C.
    Authors: Drannik AG, Nag K, Yao XD, Henrick BM, Sallenave JM, Rosenthal KL
    PLoS ONE, 2012;7(4):e35866.
    Species: Human
    Sample Types: Cell Culture Supernates
  180. ERK5 protein promotes, whereas MEK1 protein differentially regulates, the Toll-like receptor 2 protein-dependent activation of human endothelial cells and monocytes.
    Authors: Wilhelmsen K, Mesa K, Lucero J, Xu F, Hellman J
    J Biol Chem, 2012;287(32):26478-94.
    Species: Human
    Sample Types: Cell Culture Supernates
  181. Elevated adaptive immune responses are associated with latent infections of Wuchereria bancrofti.
    Authors: Arndts K, Deininger S, Specht S, Klarmann U, Mand S, Adjobimey T, Debrah AY, Batsa L, Kwarteng A, Epp C, Taylor M, Adjei O, Layland LE, Hoerauf A
    PLoS Negl Trop Dis, 2012;6(4):e1611.
    Species: Human
    Sample Types: Cell Culture Supernates
  182. Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation.
    Eur J Clin Nutr, 2012;66(9):1072-4.
    Species: Human
    Sample Types: Plasma
  183. Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse.
    J Neuroinflammation, 2012;9(0):203.
    Species: Human
    Sample Types: Cell Culture Supernates
  184. Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.
    Authors: Marcondes AM, Li X, Tabellini L, Bartenstein M, Kabacka J, Sale GE, Hansen JA, Dinarello CA, Deeg HJ
    Blood, 2011;118(18):5031-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  185. GLI2 Transcription Factor Mediates Cytokine Cross-talk in the Tumor Microenvironment.
    Authors: Elsawa SF, Almada LL, Ziesmer SC, Novak AJ, Witzig TE, Ansell SM, Fernandez-Zapico ME
    J. Biol. Chem., 2011;286(24):21524-34.
    Species: Human
    Sample Types: Cell Culture Supernates
  186. IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes.
    Authors: Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A
    J. Immunol., 2010;184(9):4880-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  187. Enrichment of Foxp3+ CD4 regulatory T cells in migrated T cells to IL-6- and IL-8-expressing tumors through predominant induction of CXCR1 by IL-6.
    Authors: Eikawa S, Ohue Y, Kitaoka K
    J. Immunol., 2010;185(11):6734-40.
    Species: Human
    Sample Types: Pleural Effusion
  188. PI3K/p110{delta} is a novel therapeutic target in multiple myeloma.
    Authors: Ikeda H, Hideshima T, Fulciniti M
    Blood, 2010;116(9):1460-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  189. Soluble erythropoietin receptor contributes to erythropoietin resistance in end-stage renal disease.
    Authors: Khankin EV, Mutter WP, Tamez H
    PLoS ONE, 2010;5(2):e9246.
    Species: Human
    Sample Types: Serum
  190. TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23.
    Authors: Aliahmadi E, Gramlich R, Grutzkau A, Hitzler M, Kruger M, Baumgrass R, Schreiner M, Wittig B, Wanner R, Peiser M
    Eur. J. Immunol., 2009;39(5):1221-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  191. Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway.
    Authors: Scutera S, Fraone T, Musso T, Cappello P, Rossi S, Pierobon D, Orinska Z, Paus R, Bulfone-Paus S, Giovarelli M
    J. Immunol., 2009;183(5):3004-13.
    Species: Human
    Sample Types: Cell Culture Supernates
  192. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
    Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
    Circulation, 2009;119(10):1424-32.
    Species: Human
    Sample Types: Plasma
  193. Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling.
    Authors: Huang QQ, Sobkoviak R, Jockheck-Clark AR, Shi B, Mandelin AM, Tak PP, Haines GK, Nicchitta CV, Pope RM
    J. Immunol., 2009;182(8):4965-73.
    Species: Human
    Sample Types: Cell Culture Supernates
  194. Carbon dioxide inhalation causes pulmonary inflammation.
    Authors: Abolhassani M, Guais A, Chaumet-Riffaud P, Sasco AJ, Schwartz L
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(4):L657-65.
    Species: Human
    Sample Types: Cell Culture Supernates
  195. Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1.
    Authors: Christophi GP, Panos M, Hudson CA, Tsikkou C, Mihai C, Mejico LJ, Jubelt B, Massa PT
    Clin. Immunol., 2009;133(1):27-44.
    Species: Human
    Sample Types: Plasma
  196. Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.
    Authors: Hawn TR, Scholes D, Wang H, Li SS, Stapleton AE, Janer M, Aderem A, Stamm WE, Zhao LP, Hooton TM
    PLoS ONE, 2009;4(12):e8300.
    Species: Human
    Sample Types: Urine
  197. Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms.
    Authors: Correale J, Farez M
    J. Immunol., 2009;183(9):5999-6012.
    Species: Human
    Sample Types: Cell Culture Supernates
  198. Reduced ex vivo interleukin-6 production by dietary fish oil is not modified by linoleic acid intake in healthy men.
    Authors: Damsgaard CT, Lauritzen L, Calder PC, Kjaer TR, Frokiaer H
    J. Nutr., 2009;139(7):1410-4.
    Species: Human
    Sample Types: Cell Culture Supernates
  199. Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
    Authors: Hao Q, Wang L, Tang H
    Am. J. Physiol., Cell Physiol., 2009;296(4):C821-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  200. Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.
    Authors: Ahmed S, Marotte H, Kwan K, Ruth JH, Campbell PL, Rabquer BJ, Pakozdi A, Koch AE
    Proc. Natl. Acad. Sci. U.S.A., 2008;105(38):14692-7.
    Species: Human
    Sample Types: Tissue Homogenates
  201. Reduced response to adiponectin and lower abundance of adiponectin receptor proteins in type 2 diabetic monocytes.
    Authors: Weigert J, Neumeier M, Wanninger J, Wurm S, Kopp A, Schober F, Filarsky M, Schaffler A, Zeitoun M, Aslanidis C, Buechler C
    FEBS Lett., 2008;582(12):1777-82.
    Species: Human
    Sample Types: Cell Culture Supernates
  202. p38 mitogen-activated protein kinase inhibitor LY2228820 enhances bortezomib-induced cytotoxicity and inhibits osteoclastogenesis in multiple myeloma; therapeutic implications.
    Authors: Ishitsuka K, Hideshima T, Neri P, Vallet S, Shiraishi N, Okawa Y, Shen Z, Raje N, Kiziltepe T, Ocio EM, Chauhan D, Tassone P, Munshi N, Campbell RM, Dios AD, Shih C, Starling JJ, Tamura K, Anderson KC
    Br. J. Haematol., 2008;141(5):598-606.
    Species: Human
    Sample Types: Cell Culture Supernates
  203. Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma.
    Authors: Breitkreutz I, Raab MS, Vallet S, Hideshima T, Raje N, Mitsiades C, Chauhan D, Okawa Y, Munshi NC, Richardson PG, Anderson KC
    Leukemia, 2008;22(10):1925-32.
    Species: Human
    Sample Types: Cell Culture Supernates
  204. Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12.
    Authors: Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M
    J. Immunol., 2008;180(9):6000-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  205. Altered interleukin-6 receptor, IL-6R and gp130, production and expression and decreased SOCS-3 expression in placentas from women with pre-eclampsia.
    Authors: Zhao S, Gu Y, Dong Q, Fan R, Wang Y
    Placenta, 2008;29(12):1024-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  206. Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages.
    Authors: Birrell MA, Wong S, Catley MC, Belvisi MG
    J. Cell. Physiol., 2008;214(1):27-37.
    Species: Human
    Sample Types: Cell Culture Supernates
  207. Adenosine receptors in regulation of dendritic cell differentiation and function.
    Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
    Blood, 2008;112(5):1822-31.
    Species: Human
    Sample Types: Cell Culture Supernates
  208. Helminth infections associated with multiple sclerosis induce regulatory B cells.
    Authors: Correale J, Farez M, Razzitte G
    Ann. Neurol., 2008;64(2):187-99.
    Species: Human
    Sample Types: Cell Culture Supernates
  209. Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses.
    Authors: Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG
    J. Biol. Chem., 2007;282(44):31882-90.
    Species: Human
    Sample Types: Cell Culture Supernates
  210. Early cytokine responses after percutaneous magnetic resonance imaging guided laser thermoablation of malignant liver tumors.
    Authors: Kallio R, Sequeiros R, Surcel HM, Ohtonen P, Kiviniemi H, Syrjala H
    Cytokine, 2007;34(5):278-83.
    Species: Human
    Sample Types: Serum
  211. Elevated urinary VCAM-1, P-selectin, soluble TNF receptor-1, and CXC chemokine ligand 16 in multiple murine lupus strains and human lupus nephritis.
    Authors: Wu T, Xie C, Wang HW, Zhou XJ, Schwartz N, Calixto S, Mackay M, Aranow C, Putterman C, Mohan C
    J. Immunol., 2007;179(10):7166-75.
    Species: Human
    Sample Types: Urine
  212. Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myeloma.
    Authors: Breitkreutz I, Raab MS, Vallet S, Hideshima T, Raje N, Chauhan D, Munshi NC, Richardson PG, Anderson KC
    Br. J. Haematol., 2007;139(1):55-63.
    Species: Human
    Sample Types: Cell Culture Supernates
  213. Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling.
    Authors: Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M
    J. Clin. Invest., 2007;117(12):3664-3672.
    Species: Human
    Sample Types: Cell Culture Supernates
  214. Influence of microvascular endothelial cells on transcriptional regulation of proximal tubular epithelial cells.
    Authors: Aydin S, Signorelli S, Lechleitner T, Joannidis M, Pleban C, Perco P, Pfaller W, Jennings P
    Am. J. Physiol., Cell Physiol., 2007;294(2):C543-54.
    Species: Human
    Sample Types: Cell Culture Supernates
  215. Preadipocyte response and impairment of differentiation in an inflammatory environment.
    Authors: Poulain-Godefroy O, Froguel P
    Biochem. Biophys. Res. Commun., 2007;356(3):662-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  216. Cytokine response to strenuous exercise in athletes and non-athletes--an adaptive response.
    Authors: Gokhale R, Chandrashekara S, Vasanthakumar KC
    Cytokine, 2007;40(2):123-7.
    Species: Human
    Sample Types: Plasma
  217. The effects of dexamethasone and dehydroepiandrosterone (DHEA) on cytokines and receptor expression in a human osteoblastic cell line: potential steroid-sparing role for DHEA.
    Authors: Harding G, Mak YT, Evans B, Cheung J, MacDonald D, Hampson G
    Cytokine, 2006;36(1):57-68.
    Species: Human
    Sample Types: Cell Culture Supernates
  218. Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk.
    Authors: LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO
    J. Immunol., 2006;176(6):3742-52.
    Species: Human
    Sample Types: Cell Culture Supernates
  219. Comparison of serum levels of inflammatory markers in patients with coronary vasospasm without significant fixed coronary artery disease versus patients with stable angina pectoris and acute coronary syndromes with significant fixed coronary artery disease.
    Authors: Hung MJ, Cherng WJ, Cheng CW, Li LF
    Am. J. Cardiol., 2006;97(10):1429-34.
    Species: Human
    Sample Types: Serum
  220. TLR3 can directly trigger apoptosis in human cancer cells.
    Authors: Salaun B, Coste I, Rissoan MC, Lebecque SJ, Renno T
    J. Immunol., 2006;176(8):4894-901.
    Species: Human
    Sample Types: Cell Culture Supernates
  221. A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression.
    Authors: Macagno A, Molteni M, Rinaldi A
    J. Exp. Med., 2006;203(6):1481-92.
    Species: Human
    Sample Types: Cell Culture Supernates
  222. Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease.
    Authors: Birrell MA, Wong S, Dekkak A, De Alba J, Haj-Yahia S, Belvisi MG
    J. Pharmacol. Exp. Ther., 2006;318(2):741-50.
    Species: Human
    Sample Types: Cell Culture Supernates
  223. ADAM-9 (MDC-9/meltrin-gamma), a member of the a disintegrin and metalloproteinase family, regulates myeloma-cell-induced interleukin-6 production in osteoblasts by direct interaction with the alpha(v)beta5 integrin.
    Authors: Karadag A, Zhou M, Croucher PI
    Blood, 2006;107(8):3271-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  224. Microbial exposure, symptoms and inflammatory mediators in nasal lavage fluid of kitchen and clerical personnel in schools.
    Authors: Lignell U, Meklin T, Putus T, Vepsalainen A, Roponen M, Torvinen E, Reeslev M, Pennanen S, Hirvonen MR, Kalliokoski P, Nevalainen A
    Int J Occup Med Environ Health, 2005;18(2):139-50.
    Species: Human
    Sample Types: Nasal Lavage Fluid
  225. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists.
    Authors: Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M
    Eur. J. Immunol., 2005;35(8):2459-70.
    Species: Human
    Sample Types: Cell Culture Supernates
  226. Pre-interleukin-1alpha expression reduces cell growth and increases interleukin-6 production in SaOS-2 osteosarcoma cells: Differential inhibitory effect of interleukin-1 receptor antagonist (icIL-1Ra1).
    Authors: Palmer G, Trolliet S, Talabot-Ayer D, Mezin F, Magne D, Gabay C
    Cytokine, 2005;31(2):153-60.
    Species: Human
    Sample Types: Cell Culture Supernates
  227. Biocompatibility pattern of a bicarbonate/lactate-buffered peritoneal dialysis fluid in APD: a prospective, randomized study.
    Authors: Fusshoeller A, Plail M, Grabensee B, Plum J
    Nephrol. Dial. Transplant., 2004;19(8):2101-6.
    Species: Human
    Sample Types: Peritoneal Dialysate
  228. IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate.
    Authors: Miranda-Carus ME, Balsa A, Benito-Miguel M, Perez de Ayala C, Martin-Mola E
    J. Immunol., 2004;173(2):1463-76.
    Species: Human
    Sample Types: Cell Culture Supernates
  229. Comparison of inflammatory elements in nasal lavage and induced sputum following occupational exposure to moldy-building microbes.
    Authors: Purokivi M, Hirvonen MR, Roponen M, Randell J, Vahteristo M, Tukiainen H
    Inhal Toxicol, 2002;14(6):653-62.
    Species: Human
    Sample Types: Sputum
  230. The correlation of adhesions and peritoneal fluid cytokine concentrations: a pilot study.
    Authors: Cheong YC, Laird SM, Shelton JB, Ledger WL, Li TC, Cooke ID
    Hum. Reprod., 2002;17(4):1039-45.
    Species: Human
    Sample Types: Peritoneal Fluid
  231. IL-1, IL-6 and TNF-alpha concentrations in the peritoneal fluid of women with pelvic adhesions.
    Authors: Cheong YC, Shelton JB, Laird SM, Richmond M, Kudesia G, Li TC, Ledger WL
    Hum. Reprod., 2002;17(1):69-75.
    Species: Human
    Sample Types: Peritoneal Fluid
  232. Inflammatory mediators in nasal lavage, induced sputum and serum of employees with rheumatic and respiratory disorders.
    Authors: Roponen M, Kiviranta J, Seuri M, Tukiainen H, Myllykangas-Luosujarvi R, Hirvonen MR
    Eur. Respir. J., 2001;18(3):542-8.
    Species: Human
    Sample Types: Serum
  233. Reproducibility of measurements of exhaled NO, and cell count and cytokine concentrations in induced sputum.
    Authors: Purokivi M, Randell J, Hirvonen MR, Tukiainen H
    Eur. Respir. J., 2000;16(2):242-6.
    Species: Human
    Sample Types: Sputum
  234. Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients.
    Authors: Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S
    Mucosal Immunol, 0;5(2):140-9.
    Species: Human
    Sample Types: Cell Culture Supernates

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Human IL-6 DuoSet ELISA
By Anonymous on 03/30/2019
Sample Tested: Purified Standard
Human IL-6 DuoSet ELISA DY206
Human IL-6 DuoSet ELISA
By Anonymous on 01/16/2019
Sample Tested: Cell Culture Media
Human IL-6 DuoSet ELISA DY206
Human IL-6 DuoSet ELISA
By Anonymous on 01/03/2019
Sample Tested: Cell culture supernatant
Human IL-6 DuoSet ELISA
By Anonymous on 09/11/2018
Sample Tested: Purified Standard
Human IL-6 DuoSet ELISA DY206
Human IL-6 DuoSet ELISA
By Anonymous on 12/18/2017
Sample Tested: Peripheral blood mononuclear cells (PBMCs)
Human IL-6 DuoSet ELISA DY206
Human IL-6 DuoSet ELISA
By Anonymous on 10/20/2017
Sample Tested: Cell culture supernatant
Human IL-6 DuoSet ELISA
By Anonymous on 05/31/2017
Sample Tested: human serum
Human IL-6 DuoSet ELISA DY206
Human IL-6 DuoSet ELISA
By Anonymous on 08/24/2016
Sample Tested: HUVEC human umbilical vein endothelial cells
Human IL-6 DuoSet ELISA DY206
Human IL-6 DuoSet ELISA, 15 Plate
By Anonymous on 02/25/2016
Sample Tested: NHEK human normal epidermal keratinocytes
Human IL-6 DuoSet ELISA, 15 Plate DY206