Human VEGF165b Antibody
Human VEGF165b Antibody Summary
TCRSLTRKD
Accession # AAL27435
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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VEGF165bin Human Placenta. VEGF165bwas detected in immersion fixed paraffin-embedded sections of human placenta using Mouse Anti-Human VEGF165bMonoclonal Antibody (Catalog # MAB3045) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific staining was localized to syncytiotrophoblasts. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
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Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: VEGF
VEGF165b is the protein resulting from an mRNA splice variant of VEGF. Alternative exon usage results in a 165 amino acid product that is identical to VEGF165 except for 6 unique amino acids at the C-terminus. VEGF165b inhibits proliferation and migration of endothelial cells and is down-regulated in renal cell carcinomas.
Product Datasheets
Citations for Human VEGF165b Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells
Authors: T Jia, T Jacquet, F Dalonneau, P Coudert, E Vaganay, C Exbrayat-H, J Vollaire, V Josserand, F Ruggiero, JL Coll, B Eymin
Bmc Biology, 2021;19(1):173.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Contribution of the VEGF system to the follicular persistence associated with bovine cystic ovaries
Authors: AF Stassi, F Gasser, MML Velázquez, EM Belotti, NC Gareis, F Rey, HH Ortega, NR Salvetti, ME Baravalle
Theriogenology, 2019;138(0):52-65.
Species: Bovine
Sample Types: Tissue Homogenates
Applications: Western Blot -
Contribution of the VEGF system to the follicular persistence associated with bovine cystic ovaries
Authors: AF Stassi, F Gasser, MML Velázquez, EM Belotti, NC Gareis, F Rey, HH Ortega, NR Salvetti, ME Baravalle
Theriogenology, 2019;138(0):52-65.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
Bone marrow-derived cells are implicated as a source of lymphatic endothelial progenitors in human breast cancer.
Authors: Van't Hull E, Bron S, Henry L, Ifticene-Treboux A, Turrini R, Coukos G, Delaloye J, Doucey M
Oncoimmunology, 2014;3(0):e29080.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The role of VEGF-A165b in trophoblast survival.
Authors: Bills V, Hamdollah-Zadeh M, Soothill P, Harper S, Bates D
BMC Pregnancy Childbirth, 2014;14(0):278.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Detection of VEGF-A(xxx)b isoforms in human tissues.
Authors: Bates, David O, Mavrou, Athina, Qiu, Yan, Carter, James G, Hamdollah-Zadeh, Maryam, Barratt, Shaney, Gammons, Melissa, Millar, Ann B, Salmon, Andrew H, Oltean, Sebastia, Harper, Steven J
PLoS ONE, 2013;8(7):e68399.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
The transcription factor E2F1 and the SR protein SC35 control the ratio of pro-angiogenic versus antiangiogenic isoforms of vascular endothelial growth factor-A to inhibit neovascularization in vivo.
Authors: Merdzhanova G, Gout S, Keramidas M, Edmond V, Coll JL, Brambilla C, Brambilla E, Gazzeri S, Eymin B
Oncogene, 2010;29(39):5392-403.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Western Blot -
VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo.
Authors: Rennel ES, Varey AH, Churchill AJ, Wheatley ER, Stewart L, Mather S, Bates DO, Harper SJ
Br. J. Cancer, 2009;101(7):1183-93.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
The endogenous anti-angiogenic family of splice variants of VEGF, VEGFxxxb, are down-regulated in pre-eclamptic placentae at term.
Authors: Bates DO, MacMillan PP, Manjaly JG, Qiu Y, Hudson SJ, Bevan HS, Hunter AJ, Soothill PW, Read M, Donaldson LF, Harper SJ
Clin. Sci., 2006;110(5):575-85.
Species: Human
Sample Types: Tissue Homogenates
Applications: ELISA Development -
VEGF in the lung: a role for novel isoforms.
Authors: Varet, Julia, Varet J, Douglas SK, Douglas, Samantha, Gilmartin, Laura, Gilmartin L, Medford, Andrew R, Bates, David O, Harper, Steven J, Millar, Ann B
Am J Physiol Lung Cell Mol Physiol, 0;298(6):L768-74.
Species: Human
Sample Types: BALF
Applications: ELISA Development
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Average Rating: 5 (Based on 2 Reviews)
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