Lysine Methyltransferase Inhibitors: Products

EZH2 histone methyltransferase inhibitor

Very high affinity and selective EZH2 inhibitor

3-Deazaneplanocin A hydrochloride synthesized to Ancillary Material Grade

Potent and selective EZH2/EZH1 inhibitor

SETD8 inhibitor; also CDK4 inhibitor

GLP and G9a inhibitor

Potent G9a and GLP inhibitor

Selective G9a and GLP inhibitor

SUV39H1 inhibitor

Potent and selective SETD7 inhibitor

Potent and selective G9a and GLP inhibitor

Potent and selective G9a/GLP inhibitor

Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)

Highly potent DOT1L inhibitor

Highly potent and selective DOT1L inhibitor; cell permeable

Potent and selective SAM-competitive EZH2 inhibitor

Potent and selective SAM-competitive EZH2 inhibitor

Potent and selective SUV420H1/H2 inhibitor

Highly potent and SAM-competitive EZH2 inhibitor

Potent and selective SMYD3 inhibitor

Nuclear receptor-binding SET domain (NSD) 3 antagonist; selectively binds PWWP1 domain

Potent PRDM9 inhibitor

Antagonizes PWWP1 interaction with nucleosomal H3K36me2, alters NSD2 nucleolar localization

Selective ASH1L histone methyltransferase inhibitor

Potent and selective EED inhibitor