Mouse IL-6 DuoSet ELISA

Catalog # Availability Size / Price Qty
DY406
DY406-05
Ancillary Products Available
Mouse IL-6 ELISA Standard Curve
1 Image
Product Details
Procedure
Citations (294)
FAQs
Supplemental Products
Reviews (20)

Mouse IL-6 DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Sufficient Materials
For five or fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse IL-6. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

Data Example

Mouse IL-6 ELISA Standard Curve

Product Datasheets

Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-6

IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It contributes to chronic inflammation in obesity, insulin resistance, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis. IL-6 signals through a receptor complex of IL-6 R alpha and gp130. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 R alpha are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 R alpha elicit responses from gp130-expressing cells that lack cell surface IL-6 R alpha.

Long Name:
Interleukin 6
Entrez Gene IDs:
3569 (Human); 16193 (Mouse); 24498 (Rat); 399500 (Porcine); 280826 (Bovine); 403985 (Canine); 100034196 (Equine); 493687 (Feline); 463288 (Primate); 100008733 (Rabbit)
Alternate Names:
B cell stimulatory factor-2; B-cell differentiation factor; BSF-2; BSF2CTL differentiation factor; CDF; HGFHSFIFNB2Hybridoma growth factor; IFN-beta-2; IL6; IL-6; IL-6B-cell stimulatory factor 2; Interferon beta-2; interleukin 6 (interferon, beta 2); interleukin BSF-2; interleukin-6; MGI-2A

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

Citations for Mouse IL-6 DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

294 Citations: Showing 1 - 10
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  1. Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice
    Authors: AC Luissint, HC Williams, W Kim, S Flemming, V Azcutia, RS Hilgarth, MNO Leary, TL Denning, A Nusrat, CA Parkos
    Mucosal Immunol, 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  2. Effects of IGF-1 isoforms on muscle growth and sarcopenia
    Authors: F Ascenzi, L Barberi, G Dobrowolny, A Villa Nova, C Nicoletti, E Rizzuto, N Rosenthal, BM Scicchitan, A Musarò
    Aging Cell, 2019;0(0):e12954.
    Species: Mouse
    Sample Types: Serum
  3. Effect of Saururus chinensis leaves extract on type II collagen-induced arthritis mouse model
    Authors: JH Nho, HJ Lee, HK Jung, JH Jang, KH Lee, AH Kim, TK Sung, HW Cho
    BMC Complement Altern Med, 2019;19(1):2.
    Species: Mouse
    Sample Types: Serum
  4. The circadian regulator Bmal1 in joint mesenchymal cells regulates both joint development and inflammatory arthritis
    Authors: LE Hand, SH Dickson, AJ Freemont, DW Ray, JE Gibbs
    Arthritis Res. Ther., 2019;21(1):5.
    Species: Mouse
    Sample Types: Serum
  5. Water Extract of Acori Graminei Rhizoma Attenuates Features of Rheumatoid Arthritis in DBA/1 Mice
    Authors: JH Nho, AH Kim, HK Jung, MJ Lee, JH Jang, BD Yang, HJ Lee, KH Lee, KW Woo, HW Cho
    Evid Based Complement Alternat Med, 2019;2019(0):3637453.
    Species: Mouse
    Sample Types: Serum
  6. In�Vitro Macrophage Assay Predicts the In�Vivo Anti-inflammatory Potential of Exosomes from Human Mesenchymal Stromal Cells
    Authors: N Pacienza, RH Lee, EH Bae, DK Kim, Q Liu, DJ Prockop, G Yannarelli
    Mol Ther Methods Clin Dev, 2019;13(0):67-76.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  7. Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials
    Authors: F Zahedifard, H Lee, JH No, M Salimi, N Seyed, A Asoodeh, S Rafati
    PLoS Negl Trop Dis, 2019;13(2):e0007217.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  8. Modifying internal organization and surface morphology of siRNA lipoplexes by sodium alginate addition for efficient siRNA delivery
    Authors: DC Arruda, IJ Gonzalez, S Finet, L Cordova, V Trichet, GF Andrade, C Hoffmann, P Bigey, WA de Almeida, A Da Silva C, A Malachias, V Escriou
    J Colloid Interface Sci, 2019;540(0):342-353.
    Species: Mouse
    Sample Types: Serum
  9. Interleukin-37 monomer is the active form for reducing innate immunity
    Authors: EZ Eisenmesse, A Gottschlic, JS Redzic, N Paukovich, JC Nix, T Azam, L Zhang, R Zhao, JS Kieft, E The, X Meng, CA Dinarello
    Proc. Natl. Acad. Sci. U.S.A., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  10. Effect of antibiotic infused calcium sulfate/hydroxyapatite (CAS/HA) insets on implant-associated osteitis in a femur fracture model in mice
    Authors: L Oezel, C Büren, AO Scholz, J Windolf, CD Windolf
    PLoS ONE, 2019;14(3):e0213590.
    Species: Mouse
    Sample Types: Wound Lavage Fluid
  11. Exercise-induced AMPK activation and IL-6 muscle production are disturbed in adiponectin knockout mice
    Authors: TA Diniz, JCJ Aquino Jún, FC Mosele, C Cabral-San, EA Lima Junio, AAS Teixeira, FS Lira, JC Rosa Neto
    Cytokine, 2019;119(0):71-80.
    Species: Mouse
    Sample Types: Tissue Homogenates
  12. Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury
    Authors: G Thomi, D Surbek, V Haesler, M Joerger-Me, A Schoeberle
    Stem Cell Res Ther, 2019;10(1):105.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  13. The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1?-dependent manner in macrophages
    Authors: OM Finucane, J Sugrue, A Rubio-Arai, MV Guillot-Se, MA Lynch
    Sci Rep, 2019;9(1):4034.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  14. Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice
    Authors: Z Gong, J Huang, B Xu, Z Ou, L Zhang, X Lin, X Ye, X Kong, D Long, X Sun, X He, L Xu, Q Li, A Xuan
    J Neuroinflammation, 2019;16(1):62.
    Species: Mouse
    Sample Types: Tissue Homogenates
  15. Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis
    Authors: V Koliaraki, N Chalkidi, A Henriques, C Tzaferis, A Polykratis, A Waisman, W Muller, DJ Hackam, M Pasparakis, G Kollias
    Cell Rep, 2019;26(3):536-545.e4.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  16. NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin
    Authors: AML Scantleber, M Uil, LM Butter, R Poelman, N Claessen, SE Girardin, S Florquin, JJTH Roelofs, JC Leemans
    PLoS ONE, 2019;14(3):e0214437.
    Species: Mouse
    Sample Types: Tissue Homogenates
  17. Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism
    Authors: JL Fachi, JS Felipe, LP Pral, BK da Silva, RO Corrêa, MCP de Andrade, DM da Fonseca, PJ Basso, NOS Câmara, ÉL de Sales E, F Dos Santos, SES Guima, AM Thomas, JC Setubal, YT Magalhães, FL Forti, T Candreva, HG Rodrigues, MB de Jesus, SR Consonni, ADS Farias, P Varga-Weis, MAR Vinolo
    Cell Rep, 2019;27(3):750-761.e7.
    Species: Mouse
    Sample Types: Tissue Homogenates
  18. Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice
    Authors: VB Lê, J Dubois, C Couture, MH Cavanagh, O Uyar, A Pizzorno, M Rosa-Calat, MÈ Hamelin, G Boivin
    PLoS Pathog., 2019;15(4):e1007689.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  19. PtdIns3P phosphatases MTMR3 and MTMR4 negatively regulate innate immune responses to DNA through modulating STING trafficking
    Authors: DDP Putri, T Kawasaki, M Murase, T Sueyoshi, T Deguchi, D Ori, S Suetsugu, T Kawai
    J. Biol. Chem., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  20. Immunomodulatory effects of cyanobacterial toxin cylindrospermopsin on innate immune cells
    Authors: Z Moosova, M Pekarova, LS Sindlerova, O Vasicek, L Kubala, L Blaha, O Adamovsky
    Chemosphere, 2019;226(0):439-446.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  21. Long noncoding RNA Malat1 regulates differential activation of macrophage and response to lung injury
    Authors: H Cui, S Banerjee, S Guo, N Xie, J Ge, D Jiang, M Zörnig, VJ Thannickal, G Liu
    JCI Insight, 2019;0(0):.
    Species: Mouse
    Sample Types: Serum
  22. A Live Salmonella Vaccine Delivering PcrV through the Type III Secretion System Protects against Pseudomonas aeruginosa
    Authors: J Aguilera-H, M García-Qui, R Romero-Flo, MJ McConnell, F Ramos-Mora
    mSphere, 2019;4(2):.
    Species: Mouse
    Sample Types: Serum
  23. GWAS for Interleukin-1? levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation
    Authors: S Offenbache, Y Jiao, SJ Kim, J Marchesan, KL Moss, L Jing, K Divaris, S Bencharit, CS Agler, T Morelli, S Zhang, L Sun, WT Seaman, D Cowley, SP Barros, JD Beck, M Munz, AS Schaefer, KE North
    Nat Commun, 2018;9(1):3686.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  24. Induction of endoplasmic reticulum stress under endotoxin tolerance increases inflammatory responses and decreases Pseudomonas aeruginosa pneumonia
    Authors: S Kim, Y Joe, SU Park, SO Jeong, JK Kim, SH Park, HO Pae, YJ Surh, J Shin, HT Chung
    J. Leukoc. Biol., 2018;0(0):.
    Species: Mouse
    Sample Types: BALF
  25. Activation of macrophage mediated host defense againstSalmonella typhimuriumbyMorus albaL
    Authors: B Chang, B Koo, H Lee, JS Oh, S Kim
    Food Nutr Res, 2018;62(0):.
    Species: Mouse
    Sample Types: Serum
  26. Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI)
    Authors: S Cicko, TC Köhler, CK Ayata, T Müller, N Ehrat, A Meyer, M Hossfeld, A Zech, F Di Virgili, M Idzko
    Oncotarget, 2018;9(55):30635-30648.
    Species: Mouse
    Sample Types: BALF
  27. Helminths-based bi-functional molecule, tuftsin-phosphorylcholine (TPC), ameliorates an established murine arthritis
    Authors: M Blank, T Bashi, J Lachnish, D Ben-Ami-Sh, O Shovman, M Fridkin, M Eisenstein, A Volkov, I Barshack, Y Shoenfeld
    PLoS ONE, 2018;13(8):e0200615.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  28. Integration of T Cell Receptor, Notch and Cytokine Signals Programs in Mouse ?? T Cell Effector Differentiation
    Authors: P Zarin, TSH In, ELY Chen, J Singh, GW Wong, M Mohtashami, DL Wiest, MK Anderson, JC Zúñiga-Pfl
    Immunol. Cell Biol., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  29. Apigenin Retards Atherogenesis by Promoting ABCA1-Mediated Cholesterol Efflux and Suppressing Inflammation
    Authors: K Ren, T Jiang, HF Zhou, Y Liang, GJ Zhao
    Cell. Physiol. Biochem., 2018;47(5):2170-2184.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  30. Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB
    Authors: Y Hayama, T Kimura, Y Takeda, S Nada, S Koyama, H Takamatsu, S Kang, D Ito, Y Maeda, M Nishide, S Nojima, H Sarashina-, T Hosokawa, Y Kinehara, Y Kato, T Nakatani, Y Nakanishi, T Tsuda, T Koba, M Okada, A Kumanogoh
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: BALF
  31. Insufficient IL-10 Production as a Mechanism Underlying the Pathogenesis of Systemic Juvenile Idiopathic Arthritis
    Authors: M Imbrechts, A Avau, J Vandenhaut, B Malengier-, K Put, T Mitera, N Berghmans, O Burton, S Junius, A Liston, L de Somer, C Wouters, P Matthys
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Plasma
  32. Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses
    Authors: L Boutens, GJ Hooiveld, S Dhingra, RA Cramer, MG Netea, R Stienstra
    Diabetologia, 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  33. Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice
    Authors: V Lamontain, T Schmid, D Weber-Stef, D Zeller, Z Jenei-Lanz, H Wajant, RH Straub, DN Männel
    Cell. Mol. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  34. An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation
    Authors: RG Carroll, Z Zas?ona, S Galván-Peñ, EL Koppe, DC Sévin, S Angiari, M Triantafil, K Triantafil, LK Modis, LA O'Neill
    J. Biol. Chem., 2018;293(15):5509-5521.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  35. Choline transport links macrophage phospholipid metabolism and inflammation
    Authors: SA Snider, KD Margison, P Ghorbani, ND LeBlond, C O'Dwyer, JR Nunes, T Nguyen, H Xu, SA Bennett, MD Fullerton
    J. Biol. Chem., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  36. Preconditioning of bone marrow-derived mesenchymal stem cells highly strengthens their potential to promote IL-6-dependent M2b polarization
    Authors: D Philipp, L Suhr, T Wahlers, YH Choi, A Paunel-Gör
    Stem Cell Res Ther, 2018;9(1):286.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  37. CD71+ Erythroid Suppressor Cells Promote Fetomaternal Tolerance through Arginase-2 and PDL-1
    Authors: C Delyea, N Bozorgmehr, P Koleva, G Dunsmore, S Shahbaz, V Huang, S Elahi
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  38. Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation
    Authors: JC d'Avila, LD Siqueira, A Mazeraud, EP Azevedo, D Foguel, HC Castro-Far, T Sharshar, F Chrétien, FA Bozza
    J Neuroinflammation, 2018;15(1):28.
    Species: Mouse
    Sample Types: Tissue Homogenates
  39. p53 in Bronchial Club Cells Facilitates Chronic Lung Inflammation by Promoting Senescence
    Authors: A Sagiv, A Bar-Shai, N Levi, M Hatzav, L Zada, Y Ovadya, L Roitman, G Manella, O Regev, J Majewska, E Vadai, R Eilam, SW Feigelson, M Tsoory, M Tauc, R Alon, V Krizhanovs
    Cell Rep, 2018;22(13):3468-3479.
    Species: Mouse
    Sample Types: BALF
  40. Complement C5a Receptor 1 Exacerbates the Pathophysiology of N.�meningitidis Sepsis and Is a Potential Target for Disease Treatment
    Authors: JB Herrmann, M Muensterma, L Strobel, A Schubert-U, TM Woodruff, SD Gray-Owen, A Klos, KO Johswich
    MBio, 2018;9(1):.
    Species: Mouse
    Sample Types: Whole Blood
  41. Anti-inflammatory properties of ursodeoxycholyl lysophosphatidylethanolamide in endotoxin-mediated inflammatory liver injury
    Authors: JM Ludwig, Y Zhang, W Chamulitra, W Stremmel, A Pathil
    PLoS ONE, 2018;13(5):e0197836.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  42. Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis
    Authors: F Fattahi, MW Russell, EA Malan, M Parlett, E Abe, FS Zetoune, PA Ward
    Biomed Res Int, 2018;2018(0):4302726.
    Species: Mouse
    Sample Types: Plasma
  43. Electrophilic properties of itaconate and derivatives regulate the�I?B?-ATF3 inflammatory axis
    Authors: M Bambouskov, L Gorvel, V Lampropoul, A Sergushich, E Loginichev, K Johnson, D Korenfeld, ME Mathyer, H Kim, LH Huang, D Duncan, H Bregman, A Keskin, A Santeford, RS Apte, R Sehgal, B Johnson, GK Amarasingh, MP Soares, T Satoh, S Akira, T Hai, C de Guzman, K Auclair, TP Roddy, SA Biller, M Jovanovic, E Klechevsky, KM Stewart, GJ Randolph, MN Artyomov
    Nature, 2018;556(7702):501-504.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  44. Myocardial Ischemia Reperfusion Injury: Apoptotic, Inflammatory and Oxidative Stress Role of Galectin-3
    Authors: S Al-Salam, S Hashmi
    Cell. Physiol. Biochem., 2018;50(3):1123-1139.
    Species: Mouse
    Sample Types: Tissue Homogenates
  45. Bovine milk-derived extracellular vesicles enhance inflammation and promote M1 polarization following agricultural dust exposure in mice
    Authors: TM Nordgren, AJ Heires, J Zempleni, BJ Swanson, C Wichman, DJ Romberger
    J. Nutr. Biochem., 2018;64(0):110-120.
    Species: Mouse
    Sample Types: BALF
  46. Eugenol as a Promising Molecule for the Treatment of Dermatitis: Antioxidant and Anti-inflammatory Activities and Its Nanoformulation
    Authors: A de Araújo, FN da Fonseca, TM Rocha, LB de Freitas, EVO Araújo, DVT Wong, RCP Lima Júnio, LKAM Leal
    Oxid Med Cell Longev, 2018;2018(0):8194849.
    Species: Mouse
    Sample Types: Tissue Homogenates
  47. DNA-PK Is Targeted by Multiple Vaccinia Virus Proteins to Inhibit DNA Sensing
    Authors: SR Scutts, SW Ember, H Ren, C Ye, CA Lovejoy, M Mazzon, DL Veyer, RP Sumner, GL Smith
    Cell Rep, 2018;25(7):1953-1965.e4.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  48. The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism
    Authors: N Eissa, P Jayaprakas, S Azimullah, SK Ojha, M Al-Houqani, FY Jalal, D ?a?ewska, K Kie?-Konon, B Sadek
    Sci Rep, 2018;8(1):13077.
    Species: Mouse
    Sample Types: Tissue Homogenates
  49. A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence
    Authors: C Wang, KA Bauckman, ASB Ross, JW Symington, MM Ligon, G Scholtes, A Kumar, HW Chang, J Twentyman, BE Fashemi, RJ Xavier, IU Mysorekar
    Autophagy, 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  50. Intravesicular Acidification Regulates Lipopolysaccharide Inflammation and Tolerance through TLR4 Trafficking
    Authors: M Murase, T Kawasaki, R Hakozaki, T Sueyoshi, DDP Putri, Y Kitai, S Sato, M Ikawa, T Kawai
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  51. Fibrosis-associated hepatocarcinogenesis revisited: Establishing standard medium-term chemically-induced male and female models
    Authors: GR Romualdo, GB Prata, TC da Silva, AAH Fernandes, FS Moreno, B Cogliati, LF Barbisan
    PLoS ONE, 2018;13(9):e0203879.
    Species: Mouse
    Sample Types: Tissue Homogenates
  52. Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis
    Authors: KME Andersson, C Wasén, L Juzokaite, L Leifsdotti, MC Erlandsson, ST Silfverswä, A Stokowska, M Pekna, M Pekny, K Olmarker, RA Heckemann, M Kalm, MI Bokarewa
    Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  53. Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine
    Authors: PK Shukla, AS Meena, V Rao, RG Rao, L Balazs, R Rao
    Sci Rep, 2018;8(1):16241.
    Species: Mouse
    Sample Types: Plasma
  54. EGF receptor plays a role in the mechanism of glutamine-mediated prevention of alcohol-induced gut barrier dysfunction and liver injury
    Authors: AS Meena, PK Shukla, P Sheth, R Rao
    J. Nutr. Biochem., 2018;64(0):128-143.
    Species: Mouse
    Sample Types: Plasma
  55. Capturing the multifactorial nature of ARDS - "Two-hit" approach to model murine acute lung injury
    Authors: S Hoegl, N Burns, M Angulo, D Francis, CM Osborne, TW Mills, MR Blackburn, HK Eltzschig, CU Vohwinkel
    Physiol Rep, 2018;6(6):e13648.
    Species: Mouse
    Sample Types: BALF
  56. Intermittent Hypoxia Activates Duration-Dependent Protective and Injurious Mechanisms in Mouse Lung Endothelial Cells
    Authors: P Wohlrab, L Soto-Gonza, T Benesch, MP Winter, IM Lang, K Markstalle, V Tretter, KU Klein
    Front Physiol, 2018;9(0):1754.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  57. Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy
    Authors: F Sato-Kanek, X Wang, S Yao, T Hosoya, FS Lao, K Messer, M Pu, NM Shukla, HB Cottam, M Chan, DA Carson, M Corr, T Hayashi
    Biomed Res Int, 2018;2018(0):8091283.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  58. Myeloperoxidase deficiency attenuates systemic and dietary iron-induced adverse effects
    Authors: X Xiao, P Saha, BS Yeoh, JA Hipp, V Singh, M Vijay-Kuma
    J. Nutr. Biochem., 2018;62(0):28-34.
    Species: Mouse
    Sample Types: Tissue Homogenates
  59. LncRNA HOTAIR regulates lipopolysaccharide-induced cytokine expression and inflammatory response in macrophages
    Authors: M Obaid, SMN Udden, P Deb, N Shihabeddi, MH Zaki, SS Mandal
    Sci Rep, 2018;8(1):15670.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  60. Genetically Engineered Resveratrol-Enriched Rice Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia Via Downregulating Mitogen-Activated Protein Kinase-Nuclear Factor Kappa B Signaling Pathway
    Authors: L Subedi, SH Baek, SY Kim
    Oxid Med Cell Longev, 2018;2018(0):8092713.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  61. Intravitreal injection of anti-Interleukin (IL)-6 antibody attenuates experimental autoimmune uveitis in mice
    Authors: J Tode, E Richert, S Koinzer, A Klettner, U Pickhinke, C Garbers, S Rose-John, B Nölle, J Roider
    Cytokine, 2017;96(0):8-15.
    Species: Mouse
    Sample Types: Tissue Homogenates
  62. CRISPR/Cas9 mediated mutation of mouse IL-1? nuclear localisation sequence abolishes expression
    Authors: MJD Daniels, AD Adamson, N Humphreys, D Brough
    Sci Rep, 2017;7(1):17077.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  63. Kyungheechunggan-Tang-01, a New Herbal Medication, Suppresses LPS-Induced Inflammatory Responses through JAK/STAT Signaling Pathway in RAW 264.7 Macrophages
    Authors: HS Han, E Jang, JS Shin, KS Inn, JH Lee, G Park, YP Jang, KT Lee
    Evid Based Complement Alternat Med, 2017;2017(0):7383104.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  64. Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance
    Authors: SY Lin, SY Hsieh, YT Fan, WC Wei, PW Hsiao, DH Tsai, TS Wu, NS Yang
    Autophagy, 2017;0(0):0.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  65. Inducing maternal inflammation promotes leptin production in offspring but does not improve allergic symptoms in a mouse model of allergic rhinitis
    Authors: A Imai, K Satoi, E Fujimoto, K Sato
    Heliyon, 2017;3(6):e00327.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  66. The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression
    Authors: MS Gresnigt, M Jaeger, RK Subbarao M, O Rasid, G Jouvion, C Fitting, WJG Melchers, TD Kanneganti, A Carvalho, O Ibrahim-Gr, FL van de Vee
    Front Immunol, 2017;8(0):1777.
    Species: Mouse
    Sample Types: BALF
  67. Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the Heart of Trypanosoma cruzi-Infected Mice
    Authors: FN Penas, D Carta, G Dmytrenko, GA Mirkin, CP Modenutti, ÁC Cevey, MJ Rada, MG Ferlin, ME Sales, NB Goren
    Front Immunol, 2017;8(0):1738.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  68. CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice
    Authors: Y Zhou, H Chen, L Liu, X Yu, GK Sukhova, M Yang, L Zhang, VC Kyttaris, GC Tsokos, IE Stillman, T Ichimura, JV Bonventre, P Libby, GP Shi
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Serum
  69. The dataset describes: HIF-1 ? expression and LPS mediated cytokine production in MKP-1 deficient bone marrow derived murine macrophages
    Authors: H Talwar, C Bauerfeld, Y Liu, L Samavati
    Data Brief, 2017;14(0):56-61.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  70. Cathelicidins Inhibit Escherichia coli-Induced TLR2 and TLR4 Activation in a Viability-Dependent Manner
    Authors: M Coorens, VAF Schneider, AM de Groot, A van Dijk, M Meijerink, JM Wells, MR Scheenstra, EJA Veldhuizen, HP Haagsman
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  71. Demyelination induced by oxidative stress is regulated by sphingosine 1-phosphate receptors
    Authors: SA O'Sullivan, M Velasco-Es, KK Dev
    Glia, 2017;0(0):.
  72. Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia mediated neurodegeneration
    Authors: L Shmuel-Gal, Y Klug, Z Porat, M Charni, B Zarmi, Y Shai
    J. Biol. Chem., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  73. Combination of a high-fat diet with sweetened condensed milk exacerbates inflammation and insulin resistance induced by each separately in mice
    Authors: LN Masi, AR Martins, AR Crisma, CL do Amaral, MR Davanso, TDA Serdan, RDC da Cunha d, MM Cruz, MIC Alonso-Val, RP Torres, J Mancini-Fi, JNB Pereira, MM da Silva R, EA Liberti, SM Hirabara, R Curi
    Sci Rep, 2017;7(1):3937.
    Species: Mouse
    Sample Types: Tissue Homogenates
  74. Visfatin Triggers Anorexia and Body Weight Loss through Regulating the Inflammatory Response in the Hypothalamic Microglia
    Authors: TH Tu, IS Nam-Goong, J Lee, S Yang, JG Kim
    Mediators Inflamm., 2017;2017(0):1958947.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  75. Both anti-TNF and CTLA4 Ig treatments attenuate the disease severity of staphylococcal dermatitis in mice
    Authors: M Na, W Wang, Y Fei, E Josefsson, A Ali, T Jin
    PLoS ONE, 2017;12(3):e0173492.
    Species: Mouse
    Sample Types: Tissue Homogenates
  76. 2-Phenylnaphthalene Derivatives Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Mediators by Downregulating of MAPK/NF-?B Pathways in RAW 264.7 Macrophage Cells
    Authors: CF Chang, KC Liao, CH Chen
    PLoS ONE, 2017;12(1):e0168945.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  77. IL-24 Promotes Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas
    Authors: BX Ross, N Gao, X Cui, TJ Standiford, J Xu, FX Yu
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  78. Elevated prostaglandin E2 post-bone marrow transplant mediates interleukin-1?-related lung injury
    Authors: GJ Martínez-C, QM Taylor, CA Wilke, AB Podsiad, BB Moore
    Mucosal Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: BALF
  79. The GLP-1 analogue lixisenatide decreases atherosclerosis in insulin-resistant mice by modulating macrophage phenotype
    Authors: Á Vinué, J Navarro, A Herrero-Ce, M García-Cub, I Andrés-Bla, S Martínez-H, JT Real, JF Ascaso, H González-N
    Diabetologia, 2017;0(0):.
    Species: Mouse
    Sample Types: Plasma
  80. MCPIP1 downregulation in clear cell renal cell carcinoma promotes vascularization and metastatic progression
    Authors: P Marona, J Górka, Z Mazurek, W Wilk, J Rys, M Majka, J Jura, K Miekus
    Cancer Res., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  81. Obesity-induced diet leads to weight gain, systemic metabolic alterations, adipose tissue inflammation, hepatic steatosis, and oxidative stress in gerbils (Meriones unguiculatus)
    Authors: LL Ventura, NC Fortes, HC Santiago, MV Caliari, MA Gomes, DR Oliveira
    PeerJ, 2017;5(0):e2967.
    Species: Gerbil
    Sample Types: Tissue Homogenates
  82. Water-soluble chitosan inhibits nerve growth factor and attenuates allergic inflammation in mite allergen-induced allergic rhinitis
    Authors: PC Chen, MH Hsieh, P Wen-ShuoKu, HF Kao, CL Hsu, JY Wang
    J. Allergy Clin. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: NLF
  83. Water-Pipe Smoke Exposure-Induced Circulatory Disturbances in Mice, and the Influence of Betaine Supplementation Thereon
    Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, A Oulhaj, BH Ali
    Cell. Physiol. Biochem, 2017;41(3):1098-1112.
    Species: Mouse
    Sample Types: Plasma
  84. Chronic Toxoplasma gondii Infection Exacerbates Secondary Polymicrobial Sepsis
    Authors: MC Souza, DM Fonseca, A Kanashiro, L Benevides, TS Medina, MS Dias, WA Andrade, G Bonfá, MAB Silva, A Gozzi, MC Borges, RT Gazzinelli, JC Alves-Filh, FQ Cunha, JS Silva
    Front Cell Infect Microbiol, 2017;7(0):116.
    Species: Mouse
    Sample Types: Serum
  85. p-Coumaroyl Anthocyanin Mixture Isolated from Tuber Epidermis of Solanum tuberosum Attenuates Reactive Oxygen Species and Pro-inflammatory Mediators by Suppressing NF-?B and STAT1/3 Signaling in LPS-Induced RAW264.7 Macrophages
    Authors: HH Lee, SG Lee, JS Shin, HY Lee, K Yoon, YW Ji, DS Jang, KT Lee
    Biol. Pharm. Bull., 2017;40(11):1894-1902.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  86. Cerium Oxide Nanoparticles in Lung Acutely Induce Oxidative Stress, Inflammation, and DNA Damage in Various Organs of Mice
    Authors: A Nemmar, P Yuvaraju, S Beegam, MA Fahim, BH Ali
    Oxid Med Cell Longev, 2017;2017(0):9639035.
    Species: Mouse
    Sample Types: Tissue Homogenates
  87. NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury
    Authors: JP Barrett, RJ Henry, S Villapol, BA Stoica, A Kumar, MP Burns, AI Faden, DJ Loane
    J Neuroinflammation, 2017;14(1):65.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  88. Influence of inflammation and nitric oxide upon platelet aggregation following deposition of diesel exhaust particles in the airways
    Authors: E Smyth, A Solomon, MA Birrell, MJ Smallwood, PG Winyard, TD Tetley, M Emerson
    Br. J. Pharmacol., 2017;0(0):.
    Species: Mouse
    Sample Types: BALF
  89. The influence of macrophage growth factors on Theiler's Murine Encephalomyelitis Virus (TMEV) infection and activation of macrophages
    Authors: KM Schneider, NB Watson, SB Minchenber, PT Massa
    Cytokine, 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  90. The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches
    Authors: RF Espírito-S, CS Meira, RDS Costa, OP Souza Filh, AF Evangelist, GHG Trossini, GM Ferreira, EDS Velozo, CF Villarreal, MB Pereira So
    PLoS ONE, 2017;12(6):e0179174.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  91. Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth
    Authors: JC Klein, K Moses, G Zelinskyy, S Sody, J Buer, S Lang, I Helfrich, U Dittmer, CJ Kirschning, S Brandau
    Nat Commun, 2017;8(0):14600.
    Species: Mouse
    Sample Types: Tissue Homogenates
  92. Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response
    Authors: M Lynch, TA Walsh, I Marszalows, AE Webb, M MacAogain, TR Rogers, H Windle, D Kelleher, MJ O'Connell, CE Loscher
    BMC Evol. Biol, 2017;17(1):90.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  93. The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity
    Authors: K Doiron, V Goyon, E Coyaud, S Rajapakse, B Raught, HM McBride
    Sci Rep, 2017;7(1):107.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  94. Sublethal doses of Dinophysistoxin-1 and Okadaic acid stimulate secretion of inflammatory factors on innate immune cells: Negative health consequences
    Authors: Miguel Del Campo
    Toxicon, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  95. Evaluating the effects of refined carbohydrate and fat diets with acute ethanol consumption using a mouse model of alcoholic liver injury
    Authors: Ana Lúcia Brunialti-
    J. Nutr. Biochem., 2016;39(0):93-100.
    Species: Mouse
    Sample Types: Tissue Homogenates
  96. Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis
    PLoS ONE, 2016;11(5):e0154630.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  97. Hemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages
    J Immunol, 2016;196(11):4650-62.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  98. Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy
    Nat Commun, 2016;7(0):13894.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  99. Expression of Par3 polarity protein correlates with poor prognosis in ovarian cancer
    BMC Cancer, 2016;16(1):897.
    Species: Human
    Sample Types: Cell Culture Supernates
  100. Poly-N-acetyl glucosamine production by Staphylococcus epidermidis cells increases their in vivo pro-inflammatory effect
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Types: Serum
  101. NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis
    Authors: Andrey Lozhkin
    J. Mol. Cell. Cardiol, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  102. Traditional medicine, Sobokchukeo?Tang, modulates the inflammatory response in adipocytes and macrophages
    Mol Med Rep, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  103. Immune Cell-Conditioned Media Suppress Prostate Cancer PC-3 Cell Growth Correlating With Decreased Proinflammatory/Anti-inflammatory Cytokine Ratios in the Media Using 5 Selected Crude Polysaccharides
    Integr Cancer Ther, 2016;15(4):NP13-NP25.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  104. Toll-Like Receptor 2 recognizes Orientia tsutsugamushi and increases susceptibility to murine experimental scrub typhus
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  105. Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge
    Authors: A Savers, O Rasid, M Parlato, M Brock, G Jouvion, B Ryffel, JM Cavaillon, G Eberl, O Ibrahim-Gr
    PLoS ONE, 2016;11(4):e0153829.
    Species: Mouse
    Sample Types: Tissue Homogenates
  106. NLRP12 negatively regulates proinflammatory cytokine production and host defense against Brucella abortus
    Eur. J. Immunol., 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  107. Immunogenic Dendritic Cell Generation from Pluripotent Stem Cells by Ectopic Expression of Runx3
    Authors: Istvan Szatmari
    J. Immunol., 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  108. Loss of IL-22 inhibits autoantibody formation in collagen-induced arthritis in mice
    Authors: OB Corneth, RM Reijmers, AM Mus, PS Asmawidjaj, JP van Hambur, N Papazian, JY Siegers, F Mourcin, R Amin, K Tarte, RW Hendriks, T Cupedo, E Lubberts
    Eur J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  109. Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization
    Sci Rep, 2016;6(0):26955.
    Species: Mouse
    Sample Types: Tissue Homogenates
  110. Brazilian red propolis improves cutaneous wound healing suppressing inflammation-associated transcription factor NF?B
    Authors: Flavia Regina Sobreira Corrêa
    Biomed. Pharmacother, 2016;86(0):162-171.
    Species: Mouse
    Sample Types: Plasma
  111. Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition
    PLoS Pathog, 2016;12(5):e1005644.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  112. Klebsiella pneumoniae Siderophores Induce Inflammation, Bacterial Dissemination, and HIF-1? Stabilization during Pneumonia
    MBio, 2016;7(5):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  113. Critical role of TSLP-responsive mucosal dendritic cells in the induction of nasal antigen-specific IgA response
    Mucosal Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  114. Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner
    Authors: Nana Owusu-Boai
    Immun Inflamm Dis, 2016;4(4):413-426.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  115. Allergen-Induced IL-6 Regulates IL-9/IL-17A Balance in CD4+ T Cells in Allergic Airway Inflammation
    J Immunol, 2016;197(7):2653-64.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  116. Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype
    Sci Rep, 2016;6(0):29712.
    Species: Human
    Sample Types: Cell Culture Supernates
  117. PROTECTIVE EFFECTS OF HUMAN AND MOUSE SOLUBLE SCAVENGER-LIKE CD6 LYMPHOCYTE RECEPTOR IN A LETHAL MODEL OF POLYMICROBIAL SEPSIS
    Authors: Mario Martínez-F
    Antimicrob. Agents Chemother, 2016;0(0):.
    Species: Mouse
    Sample Types: Plasma
  118. The circadian clock regulates inflammatory arthritis
    FASEB J, 2016;0(0):.
    Species: Mouse
    Sample Types: Serum
  119. Cannabinoid receptor 2 modulates susceptibility to experimental cerebral malaria through a CCL17-dependent mechanism
    J Biol Chem, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  120. Contribution of the Ade Resistance-Nodulation-Cell Division-Type Efflux Pumps to Fitness and Pathogenesis of Acinetobacter baumannii
    Authors: Eun-Jeong Yoon
    MBio, 2016;7(3):.
    Species: Mouse
    Sample Types: BALF
  121. Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts
    Authors: Arne Yndestad
    Biochim. Biophys. Acta, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  122. Systemic Ablation of MMP9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL-6 Expression in the Bone Marrow
    Mol Cancer Res, 2016;0(0):.
    Species: Mouse
    Sample Types: Plasma
  123. Jucara pulp supplementation improves glucose tolerance in mice.
    Authors: Oyama L, Silva F, Carnier J, de Miranda D, Santamarina A, Ribeiro E, Oller do Nascimento C, de Rosso V
    Diabetol Metab Syndr, 2016;8(0):8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  124. Differential humoral and cellular immunity induced by vaccination using plasmid DNA and protein recombinant expressing the NS3 protein of dengue virus type 3
    J. Biomed. Sci, 2016;23(1):85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  125. Chrysin promotes attenuation of depressive-like behavior and hippocampal dysfunction resulting from olfactory bulbectomy in mice
    Authors: Silvana Peterini Boeira
    Chem. Biol. Interact., 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  126. Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors.
    Authors: Canli O, Alankus Y, Grootjans S, Vegi N, Hultner L, Hoppe P, Schroeder T, Vandenabeele P, Bornkamm G, Greten F
    Blood, 2016;127(1):139-48.
    Species: Mouse
    Sample Types: Serum
  127. Indoor secondary organic aerosols formation from ozonolysis of monoterpene: An example of d-limonene with ammonia and potential impacts on pulmonary inflammations
    Authors: Rujin Huang
    Sci. Total Environ., 2016;0(0):.
    Species: Mouse
    Sample Types: BALF
  128. Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
    Sci Rep, 2016;6(0):26490.
    Species: Mouse
    Sample Types: Tissue Homogenates
  129. C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils
    J Immunol, 2016;196(5):2319-26.
    Species: Mouse
    Sample Types: BALF
  130. Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B.
    Authors: Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, Akira S, Kawai T
    J Biol Chem, 2015;290(2):1269-80.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  131. Severe neutrophil-dominated inflammation and enhanced myelopoiesis in IL-33-overexpressing CMV/IL33 mice.
    Authors: Talabot-Ayer D, Martin P, Vesin C, Seemayer C, Vigne S, Gabay C, Palmer G
    J Immunol, 2015;194(2):750-60.
    Species: Mouse
    Sample Types: Tissue Homogenates
  132. The Effect of OSM on MC3T3-E1 Osteoblastic Cells in Simulated Microgravity with Radiation.
    Authors: Goyden J, Tawara K, Hedeen D, Willey J, Oxford J, Jorcyk C
    PLoS ONE, 2015;10(6):e0127230.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  133. C1q Deficiency Promotes Pulmonary Vascular Inflammation and Enhances the Susceptibility of the Lung Endothelium to Injury.
    Authors: Shah D, Romero F, Zhu Y, Duong M, Sun J, Walsh K, Summer R
    J Biol Chem, 2015;290(49):29642-51.
    Species: Mouse
    Sample Types: BALF
  134. Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection.
    Authors: Zhao Y, Olonisakin T, Xiong Z, Hulver M, Sayeed S, Yu M, Gregory A, Kochman E, Chen B, Mallampalli R, Sun M, Silverstein R, Stolz D, Shapiro S, Ray A, Ray P, Lee J
    Mucosal Immunol, 2015;8(4):896-905.
    Species: Mouse
    Sample Types: Tissue Homogenates
  135. Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling.
    Authors: Wu Y, Wu Y, Mo S, Hsiao H, He Y, Lai M
    J Immunol, 2015;195(6):2612-23.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  136. TIR-domain-containing adapter-inducing interferon-beta (TRIF) regulates Th17-mediated intestinal immunopathology in colitis.
    Authors: Kanagavelu S, Flores C, Termini J, Riveron R, Romero L, Chung K, Ruiz J, Hyun J, Yuan X, Dagvadorj J, Fukata M
    Mucosal Immunol, 2015;8(2):296-306.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  137. Effects of High-Intensity Swimming on Lung Inflammation and Oxidative Stress in a Murine Model of DEP-Induced Injury.
    Authors: Avila L, Bruggemann T, Bobinski F, da Silva M, Oliveira R, Martins D, Mazzardo-Martins L, Duarte M, de Souza L, Dafre A, Vieira R, Santos A, Bonorino K, Hizume Kunzler D
    PLoS ONE, 2015;10(9):e0137273.
    Species: Mouse
    Sample Types: Tissue Homogenates
  138. Endoplasmic reticulum stress-induced IRE1alpha activation mediates cross-talk of GSK-3beta and XBP-1 to regulate inflammatory cytokine production.
    Authors: Kim S, Joe Y, Kim H, Kim Y, Jeong S, Pae H, Ryter S, Surh Y, Chung H
    J Immunol, 2015;194(9):4498-506.
    Species: Mouse
    Sample Types: Serum
  139. Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration.
    Authors: Levy O, Calippe B, Lavalette S, Hu S, Raoul W, Dominguez E, Housset M, Paques M, Sahel J, Bemelmans A, Combadiere C, Guillonneau X, Sennlaub F
    EMBO Mol Med, 2015;7(2):211-26.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  140. Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens.
    Authors: Kortman G, Mulder M, Richters T, Shanmugam N, Trebicka E, Boekhorst J, Timmerman H, Roelofs R, Wiegerinck E, Laarakkers C, Swinkels D, Bolhuis A, Cherayil B, Tjalsma H
    Eur J Immunol, 2015;45(9):2553-67.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  141. Alveolar Epithelial A2B Adenosine Receptors in Pulmonary Protection during Acute Lung Injury.
    Authors: Hoegl S, Brodsky K, Blackburn M, Karmouty-Quintana H, Zwissler B, Eltzschig H
    J Immunol, 2015;195(4):1815-24.
    Species: Mouse
    Sample Types: BALF
  142. The inability of wild-type rabies virus to activate dendritic cells is dependent on the glycoprotein and correlates with its low level of the de novo-synthesized leader RNA.
    Authors: Yang Y, Huang Y, Gnanadurai C, Cao S, Liu X, Cui M, Fu Z
    J Virol, 2015;89(4):2157-69.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  143. Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat Feeding.
    Authors: Jovicic N, Jeftic I, Jovanovic I, Radosavljevic G, Arsenijevic N, Lukic M, Pejnovic N
    PLoS ONE, 2015;10(7):e0134089.
    Species: Mouse
    Sample Types: Tissue Homogenates
  144. Simultaneous and dose dependent melanoma cytotoxic and immune stimulatory activity of betulin.
    Authors: Pfarr K, Danciu C, Arlt O, Neske C, Dehelean C, Pfeilschifter J, Radeke H
    PLoS ONE, 2015;10(3):e0118802.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  145. Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD.
    Authors: Sundar, Isaac K, Ahmad, Tanveer, Yao, Hongwei, Hwang, Jae-woon, Gerloff, Janice, Lawrence, B Paige, Sellix, Michael, Rahman, Irfan
    Sci Rep, 2015;4(0):9927.
    Species: Mouse
    Sample Types: BALF
  146. Human beta-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid.
    Authors: Semple F, MacPherson H, Webb S, Kilanowski F, Lettice L, McGlasson S, Wheeler A, Chen V, Millhauser G, Melrose L, Davidson D, Dorin J
    PLoS Genet, 2015;11(12):e1005673.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  147. Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2.
    Authors: Fieber C, Janos M, Koestler T, Gratz N, Li X, Castiglia V, Aberle M, Sauert M, Wegner M, Alexopoulou L, Kirschning C, Chen Z, von Haeseler A, Kovarik P
    PLoS ONE, 2015;10(3):e0119727.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  148. The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.
    Authors: Schliehe C, Flynn E, Vilagos B, Richson U, Swaminathan S, Bosnjak B, Bauer L, Kandasamy R, Griesshammer I, Kosack L, Schmitz F, Litvak V, Sissons J, Lercher A, Bhattacharya A, Khamina K, Trivett A, Tessarollo L, Mesteri I, Hladik A, Merkler D, Kubicek S, Knapp S, Epstein M, Symer D, Aderem A, Bergthaler A
    Nat Immunol, 2015;16(1):67-74.
    Species: Mouse
    Sample Types: BALF
  149. Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolism.
    Authors: Tan Z, Xie N, Cui H, Moellering D, Abraham E, Thannickal V, Liu G
    J Immunol, 2015;194(12):6082-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  150. Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis.
    Authors: Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M
    Nature, 2015;515(7525):130-3.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  151. The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling.
    Authors: Fleming B, Chandrasekaran P, Dillon L, Dalby E, Suresh R, Sarkar A, El-Sayed N, Mosser D
    J Leukoc Biol, 2015;98(3):395-407.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  152. The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures.
    Authors: O'Sullivan C, Schubart A, Mir A, Dev K
    J Neuroinflammation, 2015;13(1):31.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  153. Lysostaphin-coated titan-implants preventing localized osteitis by Staphylococcus aureus in a mouse model.
    Authors: Windolf C, Logters T, Scholz M, Windolf J, Flohe S
    PLoS ONE, 2015;9(12):e115940.
    Species: Mouse
    Sample Types: BALF
  154. Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action.
    Authors: Wang H, Sethi G, Loke W, Sim M
    PLoS ONE, 2015;10(9):e0138009.
    Species: Mouse
    Sample Types: Plasma
  155. Toll-like receptor 9 deficiency protects mice against Pseudomonas aeruginosa lung infection.
    Authors: Benmohamed F, Medina M, Wu Y, Maschalidi S, Jouvion G, Guillemot L, Chignard M, Manoury B, Touqui L
    PLoS ONE, 2014;9(3):e90466.
    Species: Mouse
    Sample Types: BALF
  156. miR-27a regulates inflammatory response of macrophages by targeting IL-10.
    Authors: Xie N, Cui H, Banerjee S, Tan Z, Salomao R, Fu M, Abraham E, Thannickal V, Liu G
    J Immunol, 2014;193(1):327-34.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  157. PPAR-gamma/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis.
    Authors: Ferreira A, Sisti F, Sonego F, Wang S, Filgueiras L, Brandt S, Serezani A, Du H, Cunha F, Alves-Filho J, Serezani C
    J Immunol, 2014;192(5):2357-65.
    Species: Mouse
    Sample Types: Serum
  158. Lack of platelet-activating factor receptor protects mice against diet-induced adipose inflammation and insulin-resistance despite fat pad expansion.
    Authors: Menezes-Garcia Z, Oliveira M, Lima R, Soriani F, Cisalpino D, Botion L, Teixeira M, Souza D, Ferreira A
    Obesity (Silver Spring), 2014;22(3):663-72.
    Species: Mouse
    Sample Types: Tissue Homogenates
  159. RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.
    Authors: Rigby R, Webb L, Mackenzie K, Li Y, Leitch A, Reijns M, Lundie R, Revuelta A, Davidson D, Diebold S, Modis Y, MacDonald A, Jackson A
    EMBO J, 2014;33(6):542-58.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  160. Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity.
    Authors: Barra, Nicole G, Palanivel, Rengasam, Denou, Emmanuel, Chew, Marianne, Gillgrass, Amy, Walker, Tina D, Kong, Josh, Richards, Carl D, Jordana, Manel, Collins, Stephen, Trigatti, Bernardo, Holloway, Alison C, Raha, Sandeep, Steinberg, Gregory, Ashkar, Ali A
    PLoS ONE, 2014;9(12):e114799.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  161. Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells.
    Authors: Gleeson E, O'Donnell J, Hams E, Ni Ainle F, Kenny B, Fallon P, Preston R
    Haematologica, 2014;99(1):185-93.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  162. LPS induces the degradation of programmed cell death protein 4 (PDCD4) to release Twist2, activating c-Maf transcription to promote interleukin-10 production.
    Authors: van den Bosch M, Palsson-Mcdermott E, Johnson D, O'Neill L
    J Biol Chem, 2014;289(33):22980-90.
  163. 25-Hydroxycholesterol acts as an amplifier of inflammatory signaling.
    Authors: Gold E, Diercks A, Podolsky I, Podyminogin R, Askovich P, Treuting P, Aderem A
    Proc Natl Acad Sci U S A, 2014;111(29):10666-71.
    Species: Mouse
    Sample Types: BALF
  164. Gene and protein expression in response to different growth temperatures and oxygen availability in Burkholderia thailandensis.
    Authors: Peano C, Chiaramonte F, Motta S, Pietrelli A, Jaillon S, Rossi E, Consolandi C, Champion O, Michell S, Freddi L, Falciola L, Basilico F, Garlanda C, Mauri P, De Bellis G, Landini P
    PLoS ONE, 2014;9(3):e93009.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  165. Artesunate reduces serum lipopolysaccharide in cecal ligation/puncture mice via enhanced LPS internalization by macrophages through increased mRNA expression of scavenger receptors.
    Authors: Li, Bin, Yu, Mengchen, Pan, Xichun, Ren, Chuanlia, Peng, Wei, Li, Xiaoli, Jiang, Weiwei, Zheng, Jiang, Zhou, Hong
    Int J Mol Sci, 2014;15(1):1143-61.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  166. Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
    Authors: Dreymueller D, Martin C, Schumacher J, Groth E, Boehm J, Reiss L, Uhlig S, Ludwig A
    J Immunol, 2014;192(2):722-31.
    Species: Mouse
    Sample Types: BALF
  167. Anti-inflammatory effects of Perilla frutescens leaf extract on lipopolysaccharide-stimulated RAW264.7 cells.
    Authors: Huang B, Lin C, Chen Y, Kao S
    Mol Med Rep, 2014;10(2):1077-83.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  168. Vitamin d deficiency reduces the immune response, phagocytosis rate, and intracellular killing rate of microglial cells.
    Authors: Djukic M, Onken M, Schutze S, Redlich S, Gotz A, Hanisch U, Bertsch T, Ribes S, Hanenberg A, Schneider S, Bollheimer C, Sieber C, Nau R
    Infect Immun, 2014;82(6):2585-94.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  169. Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy.
    Authors: Walsh K, Teijaro J, Brock L, Fremgen D, Collins P, Rosen H, Oldstone M
    J Virol, 2014;88(11):6281-93.
    Species: Mouse
    Sample Types: BALF
  170. Role of lysosomes in silica-induced inflammasome activation and inflammation in absence of MARCO.
    Authors: Biswas R, Hamilton R, Holian A
    J Immunol Res, 2014;2014(0):304180.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  171. Role of OGR1 in myeloid-derived cells in prostate cancer.
    Authors: Yan, L, Singh, L S, Zhang, L, Xu, Y
    Oncogene, 2014;33(2):157-64.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  172. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
    Authors: Tatano Y, Shimizu T, Tomioka H
    Sci Rep, 2014;4(0):4146.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  173. Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease.
    Authors: Noelker C, Morel L, Osterloh A, Alvarez-Fischer D, Lescot T, Breloer M, Gold M, Oertel W, Henze C, Michel P, Dodel R, Lu L, Hirsch E, Hunot S, Hartmann A
    J Neuroinflammation, 2014;11(0):86.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  174. Sustained Na+/H+ exchanger activation promotes gliotransmitter release from reactive hippocampal astrocytes following oxygen-glucose deprivation.
    Authors: Cengiz P, Kintner D, Chanana V, Yuan H, Akture E, Kendigelen P, Begum G, Fidan E, Uluc K, Ferrazzano P, Sun D
    PLoS ONE, 2014;9(1):e84294.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  175. A new protective role for S100A9 in regulation of neutrophil recruitment during invasive pneumococcal pneumonia.
    Authors: De Filippo K, Neill D, Mathies M, Bangert M, McNeill E, Kadioglu A, Hogg N
    FASEB J, 2014;28(8):3600-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  176. Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.
    Authors: Dowling J, Becker C, Bourke N, Corr S, Connolly D, Quinn S, Pandolfi P, Mansell A, O'Neill L
    J Biol Chem, 2014;289(10):6429-37.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  177. Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM.
    Authors: Assi H, Espinosa J, Suprise S, Sofroniew M, Doherty R, Zamler D, Lowenstein P, Castro M
    PLoS ONE, 2014;9(5):e96318.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  178. S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model.
    Authors: Kim H, Chang K, Ha T, Kim J, Ha S, Shin K, Moon C, Nacken W, Kim H, Suh Y
    PLoS ONE, 2014;9(2):e88924.
    Species: Mouse
    Sample Types: Tissue Homogenates
  179. Development and characterization of a long-term murine model of Streptococcus pneumoniae infection of the lower airways.
    Authors: Haste L, Hulland K, Bolton S, Yesilkaya H, McKechnie K, Andrew P
    Infect Immun, 2014;82(8):3289-98.
  180. Protective or deleterious role of scavenger receptors SR-A and CD36 on host resistance to Staphylococcus aureus depends on the site of infection.
    Authors: Blanchet C, Jouvion G, Fitting C, Cavaillon J, Adib-Conquy M
    PLoS ONE, 2014;9(1):e87927.
    Species: Mouse
    Sample Types: BALF
  181. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice.
    Authors: Takaoka, Yuki, Goto, Shigeru, Nakano, Toshiaki, Tseng, Hui-Peng, Yang, Shih-Min, Kawamoto, Seiji, Ono, Kazuhisa, Chen, Chao-Lon
    Sci Rep, 2014;4(0):5204.
    Species: Mouse
    Sample Types: Serum
  182. No Impairment in host defense against Streptococcus pneumoniae in obese CPEfat/fat mice.
    Authors: Mancuso P, O Brien E, Prano J, Goel D, Aronoff D
    PLoS ONE, 2014;9(9):e106420.
    Species: Mouse
    Sample Types: BALF
  183. Murine lung injury caused by Leptospira interrogans glycolipoprotein, a specific Na/K-ATPase inhibitor.
    Authors: Goncalves-de-Albuquerque C, Burth P, Silva A, de Moraes I, Oliveira F, Santelli R, Freire A, de Lima G, da Silva E, da Silva C, Morandi V, Bozza P, Younes-Ibrahim M, de Castro Faria Neto H, de Castro Faria M
    Respir Res, 2014;15(0):93.
    Species: Mouse
    Sample Types: BALF
  184. Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection.
    Authors: Teijaro J, Walsh K, Rice S, Rosen H, Oldstone M
    Proc Natl Acad Sci U S A, 2014;111(10):3799-804.
    Species: Mouse
    Sample Types: BALF
  185. Pulmonary immune responses to 2009 pandemic influenza A (H1N1) virus in mice.
    Authors: Lv J, Wang D, Hua Y, Pei S, Wang J, Hu W, Wang X, Jia N, Jiang Q
    BMC Infect Dis, 2014;14(0):197.
    Species: Mouse
    Sample Types: Tissue Homogenates
  186. The inflammasome pyrin contributes to pertussis toxin-induced IL-1beta synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis.
    Authors: Dumas A, Amiable N, de Rivero Vaccari J, Chae J, Keane R, Lacroix S, Vallieres L
    PLoS Pathog, 2014;10(5):e1004150.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  187. Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection.
    Authors: Brant F, Miranda A, Esper L, Rodrigues D, Kangussu L, Bonaventura D, Soriani F, Pinho V, Souza D, Rachid M, Weiss L, Tanowitz H, Teixeira M, Teixeira A, Machado F
    Infect Immun, 2014;82(8):3127-40.
    Species: Mouse
    Sample Types: Tissue Homogenates
  188. Signaling via tumor necrosis factor receptor 1 but not Toll-like receptor 2 contributes significantly to hydrosalpinx development following Chlamydia muridarum infection.
    Authors: Dong X, Liu Y, Chang X, Lei L, Zhong G
    Infect Immun, 2014;82(5):1833-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  189. Peripheral inflammation is associated with remote global gene expression changes in the brain.
    Authors: Thomson, Carolyn, McColl, Alison, Cavanagh, Jonathan, Graham, Gerard J
    J Neuroinflammation, 2014;11(0):73.
    Species: Mouse
    Sample Types: Plasma
  190. miR-21 attenuates lipopolysaccharide-induced lipid accumulation and inflammatory response: potential role in cerebrovascular disease.
    Authors: Feng J, Li A, Deng J, Yang Y, Dang L, Ye Y, Li Y, Zhang W
    Lipids Health Dis, 2014;13(0):27.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  191. A2B adenosine receptors prevent insulin resistance by inhibiting adipose tissue inflammation via maintaining alternative macrophage activation.
    Authors: Csoka B, Koscso B, Toro G, Kokai E, Virag L, Nemeth Z, Pacher P, Bai P, Hasko G
    Diabetes, 2014;63(3):850-66.
    Species: Mouse
    Sample Types: Plasma
  192. Micheliolide, a new sesquiterpene lactone that inhibits intestinal inflammation and colitis-associated cancer.
    Authors: Viennois E, Xiao B, Ayyadurai S, Wang L, Wang P, Zhang Q, Chen Y, Merlin D
    Lab Invest, 2014;94(9):950-65.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  193. The innate immune response elicited by Group A Streptococcus is highly variable among clinical isolates and correlates with the emm type.
    Authors: Dinis M, Plainvert C, Kovarik P, Longo M, Fouet A, Poyart C
    PLoS ONE, 2014;9(7):e101464.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  194. Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 by macrophages and increases the resistance of mice against infections.
    Authors: Redlich S, Ribes S, Schutze S, Nau R
    J Neuroinflammation, 2014;11(0):108.
    Species: Mouse
    Sample Types: Tissue Homogenates
  195. Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection.
    PLoS ONE, 2014;9(12):e114884.
    Species: Mouse
    Sample Types: Tissue Homogenates
  196. Sulfatide attenuates experimental Staphylococcus aureus sepsis through a CD1d-dependent pathway.
    Authors: Kwiecinski J, Rhost S, Lofbom L, Blomqvist M, Mansson J, Cardell S, Jin T
    Infect Immun, 2013;81(4):1114-20.
    Species: Mouse
    Sample Types: Plasma
  197. The novel cytokine interleukin-33 activates acinar cell proinflammatory pathways and induces acute pancreatic inflammation in mice.
    Authors: Kempuraj D, Twait E, Williard D, Yuan Z, Meyerholz D, Samuel I
    PLoS ONE, 2013;8(2):e56866.
    Species: Mouse
    Sample Types: Tissue Homogenates
  198. ER stress-mediated regulation of immune function under glucose-deprived condition in glial cells: up- and down-regulation of PGE2 + IFNgamma-induced IL-6 and iNOS expressions.
    Authors: Hosoi T, Oba T, Ozawa K
    Biochem Biophys Res Commun, 2013;441(2):525-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  199. A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes.
    Authors: Fevre C, Almeida A, Taront S, Pedron T, Huerre M, Prevost M, Kieusseian A, Cumano A, Brisse S, Sansonetti P, Tournebize R
    EMBO Mol Med, 2013;5(4):516-30.
    Species: Mouse
    Sample Types: Tissue Homogenates
  200. Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones.
    Authors: Beynon A, Brown M, Wright R, Rees M, Sheldon I, Davies J
    J Neuroinflammation, 2013;10(0):40.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  201. Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infection.
    Authors: Crotty Alexander, Laura E, Marsh, Brenda J, Timmer, Anjuli M, Lin, Ann E, Zainabadi, Kayvan, Czopik, Agnieszk, Guarente, Leonard, Nizet, Victor
    PLoS ONE, 2013;8(12):e84481.
    Species: Mouse
    Sample Types: Plasma
  202. Toll-like receptor 6 senses Mycobacterium avium and is required for efficient control of mycobacterial infection.
    Authors: Marinho F, de Paula R, Mendes A, de Almeida L, Gomes M, Carvalho N, Oliveira F, Caliari M, Oliveira S
    Eur J Immunol, 2013;43(9):2373-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  203. A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages.
    Authors: Gonzalez Y, Doens D, Santamaria R, Ramos M, Restrepo C, Barros de Arruda L, Lleonart R, Gutierrez M, Fernandez P
    PLoS ONE, 2013;8(12):e84107.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  204. Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice.
    Authors: Waddell A, Ahrens R, Tsai Y, Sherrill J, Denson L, Steinbrecher K, Hogan S
    J Immunol, 2013;190(9):4773-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  205. Genetic deletion of the HIF-1alpha isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model.
    Authors: Georgiev P, Belikoff B, Hatfield S, Ohta A, Sitkovsky M, Lukashev D
    Eur J Immunol, 2013;43(3):655-66.
    Species: Mouse
    Sample Types: Serum
  206. Syntaxin binding protein 1 is not required for allergic inflammation via IgE-mediated mast cell activation.
    Authors: Wu Z, MacNeil A, Berman J, Lin T
    PLoS ONE, 2013;8(3):e58560.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  207. Bee venom and its component apamin as neuroprotective agents in a Parkinson disease mouse model.
    Authors: Alvarez-Fischer D, Noelker C, Vulinovic F, Grunewald A, Chevarin C, Klein C, Oertel W, Hirsch E, Michel P, Hartmann A
    PLoS ONE, 2013;8(4):e61700.
    Species: Mouse
    Sample Types: Tissue Homogenates
  208. Calcineurin-Rcan1 interaction contributes to stem cell factor-mediated mast cell activation.
    Authors: Wu Z, Li Y, MacNeil A, Junkins R, Berman J, Lin T
    J Immunol, 2013;191(12):5885-94.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  209. Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model.
    Authors: Everitt, Aaron R, Clare, Simon, McDonald, Jacqueli, Kane, Leanne, Harcourt, Katherin, Ahras, Malika, Lall, Amar, Hale, Christin, Rodgers, Angela, Young, Douglas, Haque, Ashraful, Billker, Oliver, Tregoning, John S, Dougan, Gordon, Kellam, Paul
    PLoS ONE, 2013;8(11):e80723.
    Species: Mouse
    Sample Types: BALF
  210. TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis.
    Authors: Park Y, Yoon S, Suh H, Kim D, Park J, Jung H, Kim T, Yoon S, Min J, Na H, Lee S, Lee H, Lee Y, Lee H, Choi I
    PLoS Pathog, 2013;9(10):e1003646.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  211. Mannose receptor 1 mediates cellular uptake and endosomal delivery of CpG-motif containing oligodeoxynucleotides.
    Authors: Moseman, Annie Pa, Moseman, E Ashley, Schworer, Stephen, Smirnova, Irina, Volkova, Tatyana, von Andrian, Ulrich, Poltorak, Alexande
    J Immunol, 2013;191(11):5615-24.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  212. IRAK-M mediates Toll-like receptor/IL-1R-induced NFkappaB activation and cytokine production.
    Authors: Zhou H, Yu M, Fukuda K, Im J, Yao P, Cui W, Bulek K, Zepp J, Wan Y, Kim T, Yin W, Ma V, Thomas J, Gu J, Wang J, DiCorleto P, Fox P, Qin J, Li X
    EMBO J, 2013;32(4):583-96.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  213. Influence of hypoxia-inducible factor 1-alpha on dendritic cell differentiation and migration.
    Authors: Kohler T, Reizis B, Johnson RS, Weighardt H, Forster I
    Eur. J. Immunol., 2012;42(5):1226-36.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  214. Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localization.
    Authors: Qi, Rongsu, Singh, Divyendu, Kao, C Cheng
    J Biol Chem, 2012;287(39):32617-29.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  215. Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.
    J. Immunol., 2012;189(4):1911-9.
    Species: Mouse
    Sample Types: Serum
  216. Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
    Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
    Infect. Immun., 2012;80(1):100-9.
    Species: Mouse
    Sample Types: Serum
  217. Rosiglitazone improves survival and hastens recovery from pancreatic inflammation in obese mice.
    Authors: Pini M, Rhodes DH, Castellanos KJ
    PLoS ONE, 2012;7(7):e40944.
    Species: Mouse
    Sample Types: Plasma
  218. The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems.
    Authors: Chuquimia OD, Petursdottir DH, Rahman MJ, Hartl K, Singh M, Fernandez C
    PLoS ONE, 2012;7(2):e32125.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  219. Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis.
    Authors: Machado GB, de Oliveira AV, Saliba AM, de Lima CD, Suassuna JH, Plotkowski MC
    Respir. Res., 2011;12(0):104.
    Species: Mouse
    Sample Types: BALF
  220. The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
    Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
    J. Immunol., 2011;186(9):5425-34.
    Species: Mouse
    Sample Types: Tissue Homogenates
  221. Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus.
    Authors: Walsh KB, Teijaro JR, Wilker PR
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(29):12018-23.
    Species: Mouse
    Sample Types: BALF
  222. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
    Authors: El-Behi M, Ciric B, Dai H
    Nat. Immunol., 2011;12(6):568-75.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  223. Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection.
    Authors: Teijaro JR, Walsh KB, Cahalan S, Fremgen DM, Roberts E, Scott F, Martinborough E, Peach R, Oldstone MB, Rosen H
    Cell, 2011;146(6):980-91.
    Species: Mouse
    Sample Types: BALF
  224. CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition.
    Authors: Barber DL, Mayer-Barber KD, Feng CG
    J. Immunol., 2011;186(3):1598-607.
    Species: Mouse
    Sample Types: BALF
  225. Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia.
    Authors: Steinwede K, Tempelhof O, Bolte K, Maus R, Bohling J, Ueberberg B, Langer F, Christman JW, Paton JC, Ask K, Maharaj S, Kolb M, Gauldie J, Welte T, Maus UA
    J. Immunol., 2011;187(10):5346-56.
    Species: Mouse
    Sample Types: BALF
  226. CCL17 controls mast cells for the defense against filarial larval entry.
    Authors: Specht S, Frank JK, Alferink J, Dubben B, Layland LE, Denece G, Bain O, Forster I, Kirschning CJ, Martin C, Hoerauf A
    J. Immunol., 2011;186(8):4845-52.
    Species: Mouse
    Sample Types: Thoracic Cavity Fluid
  227. Lung-targeted overexpression of the NF-kappaB member RelB inhibits cigarette smoke-induced inflammation.
    Authors: McMillan DH, Baglole CJ, Thatcher TH, Maggirwar S, Sime PJ, Phipps RP
    Am. J. Pathol., 2011;179(1):125-33.
    Species: Mouse
    Sample Types: BALF
  228. Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.
    Authors: Le Goffic R, Leymarie O, Chevalier C, Rebours E, Da Costa B, Vidic J, Descamps D, Sallenave JM, Rauch M, Samson M, Delmas B
    PLoS Pathog., 2011;7(8):e1002202.
    Species: Mouse
    Sample Types: BALF
  229. A hypoxia- and alpha-fetoprotein-dependent oncolytic adenovirus exhibits specific killing of hepatocellular carcinomas.
    Authors: Kwon OJ, Kim PH, Huyn S, Wu L, Kim M, Yun CO
    Clin. Cancer Res., 2010;16(24):6071-82.
    Species: Mouse
    Sample Types: Serum
  230. Interleukin-15 contributes to the regulation of murine adipose tissue and human adipocytes.
    Authors: Barra NG, Reid S, MacKenzie R
    Obesity (Silver Spring), 2010;18(8):1601-7.
    Species: Mouse
    Sample Types: Serum
  231. Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity.
    Authors: Sellge G, Magalhaes JG, Konradt C, Fritz JH, Salgado-Pabon W, Eberl G, Bandeira A, Di Santo JP, Sansonetti PJ, Phalipon A
    J. Immunol., 2010;184(4):2076-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  232. Distinct roles of hepatocyte- and myeloid cell-derived IL-1 receptor antagonist during endotoxemia and sterile inflammation in mice.
    Authors: Lamacchia C, Palmer G, Bischoff L, Rodriguez E, Talabot-Ayer D, Gabay C
    J. Immunol., 2010;185(0):2516-24.
    Species: Mouse
    Sample Types: Serum
  233. Importance of TLR2 in the direct response of T lymphocytes to Schistosoma mansoni antigens.
    Authors: Burton OT, Gibbs S, Miller N, Jones FM, Wen L, Dunne DW, Cooke A, Zaccone P
    Eur. J. Immunol., 2010;40(8):2221-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  234. A novel mechanism of cytokine release in phagocytes induced by aggretin, a snake venom C-type lectin protein, through CLEC-2 ligation.
    Authors: Chang CH, Chung CH, Hsu CC, Huang TY, Huang TF
    J. Thromb. Haemost., 2010;8(11):2563-70.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  235. Toll-like receptor 4 mediates the response of epithelial and stromal cells to lipopolysaccharide in the endometrium.
    Authors: Sheldon IM, Roberts MH,
    PLoS ONE, 2010;5(9):e12906.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  236. Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice.
    Authors: Zhu M, Hug C, Kasahara DI
    Am. J. Respir. Cell Mol. Biol., 2010;43(4):487-97.
    Species: Mouse
    Sample Types: BALF
  237. A critical role for C5L2 in the pathogenesis of experimental allergic asthma.
    Authors: Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, Konig P, Gerard NP, Gerard C, Wills-Karp M, Kohl J
    J. Immunol., 2010;185(11):6741-52.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  238. Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis.
    Authors: Matsuda N, Yamamoto S, Yokoo H, Tobe K, Hattori Y
    Crit. Care Med., 2009;37(10):2791-9.
    Species: Mouse
    Sample Types: Serum
  239. E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.
    Authors: Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P
    J. Immunol., 2009;183(4):2642-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  240. IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema.
    Authors: Couillin I, Vasseur V, Charron S, Gasse P, Tavernier M, Guillet J, Lagente V, Fick L, Jacobs M, Coelho FR, Moser R, Ryffel B
    J. Immunol., 2009;183(12):8195-202.
    Species: Mouse
    Sample Types: BALF
  241. Age-associated aggravation of clinical disease after primary metapneumovirus infection of BALB/c mice.
    Authors: Darniot M, Pitoiset C, Petrella T, Aho S, Pothier P, Manoha C
    J. Virol., 2009;83(7):3323-32.
    Species: Mouse
    Sample Types: BALF
  242. IL-6 is required for airway mucus production induced by inhaled fungal allergens.
    Authors: Neveu WA, Allard JB, Dienz O, Wargo MJ, Ciliberto G, Whittaker LA, Rincon M
    J. Immunol., 2009;183(3):1732-8.
    Species: Mouse
    Sample Types: BALF
  243. TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia.
    Authors: Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S
    J. Immunol., 2009;183(3):2027-36.
    Species: Mouse
    Sample Types: Tissue Homogenates
  244. Modulation of macrophage infiltration and inflammatory activity by the phosphatase SHP-1 in virus-induced demyelinating disease.
    Authors: Christophi GP, Hudson CA, Panos M, Gruber RC, Massa PT
    J. Virol., 2009;83(2):522-39.
    Species: Mouse
    Sample Types: Tissue Homogenates
  245. Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse.
    Authors: Wang S, Wu D, Matthan NR, Lamon-Fava S, Lecker JL, Lichtenstein AH
    Atherosclerosis, 2009;204(1):147-55.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  246. Increased cytokine production in IL-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling (SOCS).
    Authors: Nold-Petry CA, Nold MF, Nielsen JW, Bustamante A, Zepp JA, Storm KA, Hong JW, Kim SH, Dinarello CA
    J. Biol. Chem., 2009;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  247. Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.
    Authors: Jaffre F, Bonnin P, Callebert J, Debbabi H, Setola V, Doly S, Monassier L, Mettauer B, Blaxall BC, Launay JM, Maroteaux L
    Circ. Res., 2009;104(1):113-23.
    Species: Mouse
    Sample Types: Plasma
  248. Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia.
    Authors: Lembo A, Pelletier M, Iyer R, Timko M, Dudda JC, West TE, Wilson CB, Hajjar AM, Skerrett SJ
    J. Immunol., 2008;180(11):7574-81.
    Species: Mouse
    Sample Types: Tissue Homogenates
  249. Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
    Authors: Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, Puccetti P, Mantovani A, Romani L
    J. Immunol., 2008;180(6):4022-31.
    Species: Mouse
    Sample Types: Tissue Homogenates
  250. Adenosine receptors in regulation of dendritic cell differentiation and function.
    Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
    Blood, 2008;112(5):1822-31.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  251. Streptococcus equi antigens adsorbed onto surface modified poly-epsilon-caprolactone microspheres induce humoral and cellular specific immune responses.
    Authors: Florindo HF, Pandit S, Goncalves LM, Alpar HO, Almeida AJ
    Vaccine, 2008;26(33):4168-77.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  252. Induction of IL-33 expression and activity in central nervous system glia.
    Authors: Hudson CA, Christophi GP, Gruber RC, Wilmore JR, Lawrence DA, Massa PT
    J. Leukoc. Biol., 2008;84(3):631-43.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  253. Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent.
    Authors: Doz E, Noulin N, Boichot E, Guenon I, Fick L, Le Bert M, Lagente V, Ryffel B, Schnyder B, Quesniaux VF, Couillin I
    J. Immunol., 2008;180(2):1169-78.
    Species: Mouse
    Sample Types: BALF
  254. Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis.
    Authors: Kaya Z, Goser S, Buss SJ, Leuschner F, Ottl R, Li J, Volkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA
    Circulation, 2008;118(20):2063-72.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  255. Modulation of ozone-induced airway hyperresponsiveness and inflammation by interleukin-13.
    Authors: Williams AS, Nath P, Leung SY, Khorasani N, McKenzie AN, Adcock IM, Chung KF
    Eur. Respir. J., 2008;32(3):571-8.
    Species: Mouse
    Sample Types: BALF
  256. Direct B cell stimulation by dendritic cells in a mouse model of lupus.
    Authors: Wan S, Zhou Z, Duan B, Morel L
    Arthritis Rheum., 2008;8(0):1741-50.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  257. VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways.
    Authors: Tiwari N, Wang CC, Brochetta C, Ke G, Vita F, Qi Z, Rivera J, Soranzo MR, Zabucchi G, Hong W, Blank U
    Blood, 2008;111(7):3665-74.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  258. Methylprednisolone improves lung mechanics and reduces the inflammatory response in pulmonary but not in extrapulmonary mild acute lung injury in mice.
    Authors: Leite-Junior JH, Garcia CS, Souza-Fernandes AB, Silva PL, Ornellas DS, Larangeira AP, Castro-Faria-Neto HC, Morales MM, Negri EM, Capelozzi VL, Zin WA, Pelosi P, Bozza PT, Rocco PR
    Crit. Care Med., 2008;36(9):2621-8.
    Species: Mouse
    Sample Types: BALF
  259. Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia.
    Authors: Schell JB, Crane CA, Smith MF, Roberts MR
    J. Neuroimmunol., 2007;189(1):75-87.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  260. The EGF receptor is required for efficient liver regeneration.
    Authors: Natarajan A, Wagner B, Sibilia M
    Proc. Natl. Acad. Sci. U.S.A., 2007;104(43):17081-6.
    Species: Mouse
    Sample Types: Serum
  261. Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.
    Authors: Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Herve C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, Arnout J, Herbert JM, Waer M, Garcia de Frutos P, Dahlback B, Carmeliet P, Hoylaerts MF, Moons L
    Blood, 2007;111(8):4096-105.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  262. Mycobacterium tuberculosis antigens specifically modulate CCR2 and MCP-1/CCL2 on lymphoid cells from human pulmonary hilar lymph nodes.
    Authors: Arias MA, Jaramillo G, Lopez YP, Mejia N, Mejia C, Pantoja AE, Shattock RJ, Garcia LF, Griffin GE
    J. Immunol., 2007;179(12):8381-91.
    Species: Human
    Sample Types: Cell Culture Supernates
  263. A synthetic analog of alpha-galactosylceramide induces macrophage activation via the TLR4-signaling pathways.
    Authors: Hung LC, Lin CC, Hung SK, Wu BC, Jan MD, Liou SH, Fu SL
    Biochem. Pharmacol., 2007;73(12):1957-70.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  264. IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice.
    Authors: Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, Schnyder B, Akira S, Quesniaux VF, Lagente V, Ryffel B, Couillin I
    J. Clin. Invest., 2007;117(12):3786-99.
    Species: Mouse
    Sample Types: BALF
  265. Deletion of TLR5 results in spontaneous colitis in mice.
    Authors: Vijay-Kumar M, Sanders CJ, Taylor RT, Kumar A, Aitken JD, Sitaraman SV, Neish AS, Uematsu S, Akira S, Williams IR, Gewirtz AT
    J. Clin. Invest., 2007;117(12):3909-21.
    Species: Mouse
    Sample Types: Serum
  266. Involvement of vitronectin in lipopolysaccaride-induced acute lung injury.
    Authors: Tsuruta Y, Park YJ, Siegal GP, Liu G, Abraham E
    J. Immunol., 2007;179(10):7079-86.
    Species: Mouse
    Sample Types: Tissue Homogenates
  267. Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis.
    Authors: Hegde A, Zhang H, Moochhala SM, Bhatia M
    J. Leukoc. Biol., 2007;82(3):678-85.
    Species: Mouse
    Sample Types: Plasma
  268. Mechanisms of interleukin-6 synthesis and release induced by interleukin-1 and cell depolarisation in neurones.
    Authors: Tsakiri N, Kimber I, Rothwell NJ, Pinteaux E
    Mol. Cell. Neurosci., 2007;37(1):110-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  269. Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells.
    Authors: Sugiyama K, Shirai R, Mukae H, Ishimoto H, Nagata T, Sakamoto N, Ishii H, Nakayama S, Yanagihara K, Mizuta Y, Kohno S
    Clin. Exp. Immunol., 2007;147(3):540-6.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  270. Interleukin 10 regulates inflammatory cytokine synthesis to protect against lipopolysaccharide-induced abortion and fetal growth restriction in mice.
    Authors: Robertson SA, Care AS, Skinner RJ
    Biol. Reprod., 2007;76(5):738-48.
    Species: Mouse
    Sample Types: Serum
  271. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
    Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
    Immunity, 2007;26(4):445-59.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  272. Interleukin-1-induced interleukin-6 synthesis is mediated by the neutral sphingomyelinase/Src kinase pathway in neurones.
    Authors: Tsakiri N, Kimber I, Rothwell NJ, Pinteaux E
    Br. J. Pharmacol., 2007;153(4):775-83.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  273. Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.
    Authors: Rabe B, Chalaris A, May U, Waetzig GH, Seegert D, Williams AS, Jones SA, Rose-John S, Scheller J
    Blood, 2007;111(3):1021-8.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  274. Glucose-6-phosphate dehydrogenase deficiency and the inflammatory response to endotoxin and polymicrobial sepsis.
    Authors: Wilmanski J, Villanueva E, Deitch EA, Spolarics Z
    Crit. Care Med., 2007;35(2):510-8.
    Species: Mouse
    Sample Types: Plasma
  275. Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection.
    Authors: Cheng W, Shivshankar P, Li Z, Chen L, Yeh IT, Zhong G
    Infect. Immun., 2007;76(2):515-22.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  276. Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis.
    Authors: Hwang SA, Wilk KM, Budnicka M, Olsen M, Bangale YA, Hunter RL, Kruzel ML, Actor JK
    Vaccine, 2007;25(37):6730-43.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  277. Role of Toll-like receptor 2 in recognition of Legionella pneumophila in a murine pneumonia model.
    Authors: Fuse ET, Tateda K, Kikuchi Y, Matsumoto T, Gondaira F, Azuma A, Kudoh S, Standiford TJ, Yamaguchi K
    J. Med. Microbiol., 2007;56(0):305-12.
    Species: Mouse
    Sample Types: Tissue Homogenates
  278. Effects of dexamethazone on LPS-induced activationand migration of mouse dendritic cells revealed by a genome-wide transcriptional analysis.
    Authors: Vizzardelli C, Pavelka N, Luchini A, Zanoni I, Bendickson L, Pelizzola M, Beretta O, Foti M, Granucci F, Nilsen-Hamilton M, Ricciardi-Castagnoli P
    Eur. J. Immunol., 2006;36(6):1504-15.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  279. A functional comparison of canine and murine bone marrow derived cultured mast cells.
    Authors: Lin TY, London CA,
    Vet. Immunol. Immunopathol., 2006;114(3):320-34.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  280. Increased pulmonary responses to acute ozone exposure in obese db/db mice.
    Authors: Lu FL, Johnston RA, Flynt L, Theman TA, Terry RD, Schwartzman IN, Lee A, Shore SA
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;290(5):L856-65.
    Species: Mouse
    Sample Types: Serum
  281. Essential role for IL-10 in resistance to lipopolysaccharide-induced preterm labor in mice.
    Authors: Robertson SA, Skinner RJ, Care AS
    J. Immunol., 2006;177(7):4888-96.
    Species: Mouse
    Sample Types: Serum
  282. Effects of dexamethasone on macrophage migration inhibitory factor production in sepsis.
    Authors: Bruhn A, Verdant C, Vercruysse V, Su F, Vray B, Vincent JL
    Shock, 2006;26(2):169-73.
    Species: Mouse
    Sample Types: Plasma
  283. The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production.
    Authors: Powell JM, Sonnenfeld G
    J. Interferon Cytokine Res., 2006;26(1):34-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  284. Exogenous platelet-activating factor acetylhydrolase reduces mortality in mice with systemic inflammatory response syndrome and sepsis.
    Authors: Gomes RN, Bozza FA, Amancio RT, Japiassu AM, Vianna RC, Larangeira AP, Gouvea JM, Bastos MS, Zimmerman GA, Stafforini DM, Prescott SM, Bozza PT, Castro-Faria-Neto HC
    Shock, 2006;26(1):41-9.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  285. Choosing the frequency of deep inflation in mice: balancing recruitment against ventilator-induced lung injury.
    Authors: Allen GB, Suratt BT, Rinaldi L, Petty JM, Bates JH
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(4):L710-7.
    Species: Mouse
    Sample Types: BALF
  286. Anti-inflammatory activity in the aqueous crude extract of the leaves of Nidularium procerum: A bromeliaceae from the Brazilian coastal rain forest.
    Authors: Amendoeira FC, Frutuoso VS, Zanon C, Chedier LM, Figueiredo MR, Kaplan MA, Bandeira-Melo C, Bozza PT, Castro-Faria-Neto HC
    Biol. Pharm. Bull., 2005;28(6):1010-5.
    Species: Mouse
    Sample Types: Pleural Fluid
  287. MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo.
    Authors: Delale T, Paquin A, Asselin-Paturel C, Dalod M, Brizard G, Bates EE, Kastner P, Chan S, Akira S, Vicari A, Biron CA, Trinchieri G, Briere F
    J. Immunol., 2005;175(10):6723-32.
    Species: Mouse
    Sample Types: Serum
  288. Comparative immunomodulatory properties of a chitosan-MDP adjuvant combination following intranasal or intramuscular immunisation.
    Authors: Moschos SA, Bramwell VW, Somavarapu S, Alpar HO
    Vaccine, 2005;23(16):1923-30.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  289. Pyocyanin production by Pseudomonas aeruginosa induces neutrophil apoptosis and impairs neutrophil-mediated host defenses in vivo.
    Authors: Allen L, Dockrell DH, Pattery T, Lee DG, Cornelis P, Hellewell PG, Whyte MK
    J. Immunol., 2005;174(6):3643-9.
    Species: Mouse
    Sample Types: BALF
  290. Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of spaceflight conditions.
    Authors: Aviles H, Belay T, Vance M, Sun B, Sonnenfeld G
    J. Appl. Physiol., 2004;97(4):1437-44.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  291. Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88.
    Authors: Fremond CM, Yeremeev V, Nicolle DM, Jacobs M, Quesniaux VF, Ryffel B
    J. Clin. Invest., 2004;114(12):1790-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  292. Adenoviral infection decreases mortality from lipopolysaccharide-induced liver failure via induction of TNF-alpha tolerance.
    Authors: Yarovinsky TO, Powers LS, Butler NS, Bradford MA, Monick MM, Hunninghake GW
    J. Immunol., 2003;171(5):2453-60.
    Species: Mouse
    Sample Types: Serum
  293. Cytokine production in association with phagocytosis of apoptotic cells by immature dendritic cells.
    Authors: Takahashi M, Kobayashi Y
    Cell. Immunol., 2003;226(2):105-15.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  294. Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells.
    Authors: Cheng Y, Young G, Lin J, Jang H, Chen C, Nong J, Chen P, Kuo C, Kao S, Liang Y, Chen H
    PLoS ONE, 0;10(11):e0142283.
    Species: Human
    Sample Types: Cell Culture Supernates

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Average Rating: 4.8 (Based on 20 Reviews)

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Mouse IL-6 DuoSet ELISA
By Anonymous on 03/13/2019
Sample Tested: PT18 mouse mast/basophil cell line

Mouse IL-6 DuoSet ELISA
By Anonymous on 12/17/2018
Sample Tested: Cell culture supernatant

Mouse IL-6 DuoSet ELISA
By Anonymous on 12/11/2018
Sample Tested: Serum and Plasma

Mouse IL-6 DuoSet ELISA
By Anonymous on 12/11/2018
Sample Tested: 3T3-L1 mouse embryonic fibroblast adipose-like cell line

Mouse IL-6 DuoSet ELISA
By Anonymous on 07/29/2018
Sample Tested: Plasma

Mouse IL-6 DuoSet ELISA
By Anonymous on 03/28/2018
Sample Tested: BMDM

Mouse IL-6 DuoSet ELISA
By Anonymous on 12/01/2017
Sample Tested: mice lung extract,mice lung protein

Mouse IL-6 DuoSet ELISA
By Anonymous on 11/22/2017
Sample Tested: mouse primary microglia cells

Excellent performance


Mouse IL-6 DuoSet ELISA
By Anonymous on 09/27/2017
Sample Tested: Peritoneal resident macrophages

Mouse IL-6 DuoSet ELISA
By Anonymous on 09/07/2017
Sample Tested: Serum and Plasma

Mouse IL-6 DuoSet ELISA
By Anonymous on 07/14/2017
Sample Tested: Cell culture supernatant

Mouse IL-6 DuoSet ELISA
By Anonymous on 05/02/2017
Sample Tested: Lung tissue

Mouse IL-6 DuoSet ELISA
By Anonymous on 04/24/2017
Sample Tested: Cell culture supernatant

Mouse IL-6 DuoSet ELISA
By Anonymous on 04/18/2017
Sample Tested: Serum

Reliable results and easy to follow protocol


Mouse IL-6 DuoSet ELISA
By Anonymous on 10/06/2016
Sample Tested: Cell culture supernatant

Mouse IL-6 DuoSet ELISA
By Anonymous on 09/30/2016
Sample Tested: Skeletal muscle

Mouse IL-6 DuoSet ELISA
By Anonymous on 08/04/2016
Sample Tested: mouse serum

Mouse IL-6 DuoSet ELISA
By Anonymous on 07/05/2016
Sample Tested: mouse BAL fluid

Mouse IL-6 DuoSet ELISA, 15 Plate
By Anonymous on 04/08/2016
Sample Tested: murine lung homogenate

consistent results, easy to use


Mouse IL-6 DuoSet ELISA, 15 Plate
By Anonymous on 10/26/2015
Sample Tested: Purified Standard

50ul of murine IL-6 Capture antibody (2ug/mL) was coated per well of a 96 well plate at 4 degrees overnight. Purified mIL-6 standard was diluted (7 fold) and assayed to ensure the quality of the ELISA. Mouse IL-6 Detector antibody was added (2h @ RT) followed by a 20 min incubation with Streptavidin-HRP. Substrate solution was added to measure mIL-6 concentration according to the manufactures protocol. The standard curve looked great as can be seen by calculation of the R- squared value. Highly recommend doing ELISA's using kits from R&D.
Buffer: 7-Fold dilution cruve was tried (only values that genrated a linear curve are shown)