Mouse TNF-alpha DuoSet ELISA Summary
* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.
This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse TNF-alpha. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.
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Product Features
- Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
- Development protocols are provided to guide further assay optimization
- Assay can be customized to your specific needs
- Economical alternative to complete kits
Kit Content
- Capture Antibody
- Detection Antibody
- Recombinant Standard
- Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)
Other Reagents Required
DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.
The components listed above may be purchased separately:
PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered
Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4
Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered
Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)
Stop Solution: 2 N H2SO4 (Catalog # DY994)
Microplates: R&D Systems (Catalog # DY990)
Plate Sealers: ELISA Plate Sealers (Catalog # DY992)
Data Example
Product Datasheets
Preparation and Storage
Background: TNF-alpha
Tumor necrosis factor alpha (TNF-alpha ), also known as cachectin and TNFSF1A, is the prototypic ligand of the TNF superfamily (1). It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism (2-5). TNF-alpha is also involved in a number of pathological conditions including asthma, Crohn's disease, rheumatoid arthritis, neuropathic pain, obesity, type 2 diabetes, septic shock, autoimmunity, and cancer (5-11).
Assay Procedure
GENERAL ELISA PROTOCOL
Plate Preparation
- Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
- Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
- Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
- Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.
Assay Procedure
- Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Repeat the aspiration/wash as in step 2.
- Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
- Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.
Citations for Mouse TNF-alpha DuoSet ELISA
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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HIF-1alpha induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury
Authors: PS Woods, LM Kimmig, KA Sun, AY Meliton, OR Shamaa, Y Tian, R Cetin-Atal, WW Sharp, RB Hamanaka, GM Mutlu
Elife, 2022;11(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Design and Synthesis of Novel 1,3,4-Oxadiazole and 1,2,4-Triazole Derivatives as Cyclooxygenase-2 Inhibitors with Anti-inflammatory and Antioxidant activity in LPS-stimulated RAW264.7 Macrophages
Authors: MMS Hamoud, NA Osman, S Rezq, H A A Abd El, A E A Hassan, HA Abdel-Fatt, DG Romero, AM Ghanim
Bioorganic chemistry, 2022;124(0):105808.
Species: Mouse
Sample Types: Cell Culture Supernates
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ADAM8 signaling drives neutrophil migration and ARDS severity
Authors: C Conrad, D Yildiz, SJ Cleary, A Margraf, L Cook, U Schlomann, B Panaretou, JL Bowser, H Karmouty-Q, J Li, NK Berg, SC Martin, A Aljohmani, SF Moussavi-H, KM Wang, JJ Tian, M Magnen, C Valet, L Qiu, JP Singer, HK Eltzschig, CAPSys Stu, W Bertrams, S Herold, N Suttorp, B Schmeck, ZT Ball, A Zarbock, MR Looney, JW Bartsch
JCI Insight, 2022;7(3):.
Species: Mouse
Sample Types: BALF
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Inhibition of mitoNEET attenuates LPS-induced inflammation and oxidative stress
Authors: S Lee, BG Seok, SJ Lee, SW Chung
Cell Death & Disease, 2022;13(2):127.
Species: Mouse
Sample Types: Cell Culture Supernates
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TNFalpha-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation
Authors: WY Huang, YL Lai, KH Liu, S Lin, HY Chen, CH Liang, HM Wu, KS Hsu
Journal of Neuroinflammation, 2022;19(1):29.
Species: Mouse
Sample Types: Plasma
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d-enantiomers of CATH-2 enhance the response of macrophages against Streptococcus suis serotype 2
Authors: RM van Harten, JLM Tjeerdsma-, A de Greeff, MD Balhuizen, A van Dijk, EJA Veldhuizen, HP Haagsman, MR Scheenstra
Journal of advanced research, 2022;36(0):101-112.
Species: Mouse
Sample Types: Cell Culture Supernates
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STING mediates neurodegeneration and neuroinflammation in nigrostriatal alpha-synucleinopathy
Authors: JT Hinkle, J Patel, N Panicker, SS Karuppagou, D Biswas, B Belingon, R Chen, S Brahmachar, O Pletnikova, JC Troncoso, VL Dawson, TM Dawson
Proceedings of the National Academy of Sciences of the United States of America, 2022;119(15):e2118819119.
Species: Mouse
Sample Types: Cell Culture Supernates
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The phosphoinositide-3-kinase (PI3K)-delta inhibitor seletalisib impairs monocyte-derived dendritic cells maturation, APC function, and promotes their migration to CCR7 and CXCR4 ligands
Authors: F Scopelliti, L Mercurio, C Cattani, V Dimartino, C Albanesi, G Costanzo, C Mirisola, S Madonna, A Cavani
Journal of leukocyte biology, 2022;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice
Authors: A Moshensky, CS Brand, H Alhaddad, J Shin, JA Masso-Silv, I Advani, D Gunge, A Sharma, S Mehta, A Jahan, S Nilaad, J Olay, W Gu, T Simonson, D Almarghala, J Pham, S Perera, K Park, R Al-Kolla, H Moon, S Das, M Byun, Z Shah, Y Sari, J Heller Bro, LE Crotty Ale
Elife, 2022;11(0):.
Species: Mouse
Sample Types: BALF
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The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model
Authors: Y Hiramatsu, K Suzuki, T Nishida, N Onoda, T Satoh, S Akira, M Ikawa, H Ikeda, J Kamei, S Derouiche, M Tominaga, Y Horiguchi
MBio, 2022;0(0):e0319721.
Species: Mouse
Sample Types: Cell Cultu
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Sevoflurane Dampens Acute Pulmonary Inflammation via the Adenosine Receptor A2B and Heme Oxygenase-1
Authors: KC Ngamsri, A Fuhr, K Schindler, M Simelitidi, M Hagen, Y Zhang, J Gamper-Tsi, FM Konrad
Cells, 2022;11(7):.
Species: Mouse
Sample Types: BALF
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TNF-alpha derived from arsenite-induced microglia activation mediated neuronal necroptosis
Authors: H Wang, Y Chen, X Liu, R Zhang, X Wang, Q Zhang, Y Wei, F Fang, Y Yuan, Q Zhou, Y Dong, S Shi, X Jiang, X Li
Ecotoxicology and environmental safety, 2022;236(0):113468.
Species: Mouse
Sample Types: Cell Culture Supernates
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Menthone Inhalation Alleviates Local and Systemic Allergic Inflammation in Ovalbumin-Sensitized and Challenged Asthmatic Mice
Authors: YH Su, JY Lin
International Journal of Molecular Sciences, 2022;23(7):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Drug-peptide supramolecular hydrogel boosting transcorneal permeability and pharmacological activity via ligand-receptor interaction
Authors: L Chen, J Deng, A Yu, Y Hu, B Jin, P Du, J Zhou, L Lei, Y Wang, S Vakal, X Li
Bioactive materials, 2022;10(0):420-429.
Species: Mouse
Sample Types: Cell Culture Supernates
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Inhibitory Effects of Saururus chinensis Extract on Receptor for Advanced Glycation End-Products-Dependent Inflammation and Diabetes-Induced Dysregulation of Vasodilation
Authors: K Hayashi, K Sato, S Ochi, S Kawano, S Munesue, A Harashima, Y Oshima, K Kimura, T Kyoi, Y Yamamoto
International Journal of Molecular Sciences, 2022;23(10):.
Species: Mouse
Sample Types: Plasma
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Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis
Authors: R Pohl, S Feder, EM Haberl, L Rein-Fisch, TS Weiss, M Spirk, A Bruckmann, N McMullen, CJ Sinal, C Buechler
Biomedicines, 2022;10(1):.
Species: Mouse
Sample Types: Cell Culture Supernates
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The Salutary Effects of Catalpol on Diesel Exhaust Particles-Induced Thrombogenic Changes and Cardiac Oxidative Stress, Inflammation and Apoptosis
Authors: A Nemmar, S Beegam, NE Zaaba, S Alblooshi, S Alseiari, BH Ali
Biomedicines, 2022;10(1):.
Species: Mouse
Sample Types: Tissue Homogenates
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A novel hybrid peptide composed of LfcinB6 and KR-12-a4 with enhanced antimicrobial, anti-inflammatory and anti-biofilm activities
Authors: C Ajish, S Yang, SD Kumar, EY Kim, HJ Min, CW Lee, SH Shin, SY Shin
Scientific Reports, 2022;12(1):4365.
Species: Mouse
Sample Types: Cell Culture Supernates
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Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice
Authors: GS McElroy, RP Chakrabart, KB D'Alessand, K Vasan, J Tan, JS Stoolman, SE Weinberg, EM Steinert, PA Reyfman, BD Singer, WC Ladiges, L Gao, J Lopéz-Barn, GRS Budinger, NS Chandel
Scientific Reports, 2022;12(1):5196.
Species: Mouse
Sample Types: Serum
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Poly epsilon-Caprolactone Nanoparticles for Sustained Intra-Articular Immune Modulation in Adjuvant-Induced Arthritis Rodent Model
Authors: E Singh, RAM Osmani, R Banerjee, AS Abu Lila, A Moin, K Almansour, HH Arab, HF Alotaibi, ES Khafagy
Pharmaceutics, 2022;14(3):.
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Nociceptor-derived Reg3gamma prevents endotoxic death by targeting kynurenine pathway in microglia
Authors: E Sugisawa, T Kondo, Y Kumagai, H Kato, Y Takayama, K Isohashi, E Shimosegaw, N Takemura, Y Hayashi, T Sasaki, MM Martino, M Tominaga, K Maruyama
Cell Reports, 2022;38(10):110462.
Species: Mouse
Sample Types: Plasma
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The Compound (E)-2-Cyano-N,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases
Authors: PR da Silva, RF do Espírit, CO Melo, FE Pachú Cava, TB Costa, YV Barbosa, YMSM E Silva, NF de Sousa, CF Villarreal, RO de Moura, VL Dos Santos
Pharmaceutics, 2022;14(1):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages
Authors: XAMH van Dieren, F Vrieling, L Smeehuijze, L Deng, JP Boogaard, CA Croes, L Temmerman, S Wetzels, E Biessen, S Kersten, R Stienstra
Proceedings of the National Academy of Sciences of the United States of America, 2022;119(12):e2114739119.
Species: Mouse
Sample Types: Cell Culture Supernates
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Prevention of the foreign body response to implantable medical devices by inflammasome inhibition
Authors: DG Barone, A Carnicer-L, P Tourlomous, RS Hamilton, M Prater, AL Rutz, IB Dimov, GG Malliaras, SP Lacour, AAB Robertson, K Franze, JW Fawcett, CE Bryant
Proceedings of the National Academy of Sciences of the United States of America, 2022;119(12):e2115857119.
Species: Mouse
Sample Types: Cell Culture Supernates
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Fibrotic lung disease inhibits innate immune responses to Staphylococcal pneumonia via impaired neutrophil and macrophage function
Authors: HI Warheit-Ni, SJ Edwards, S SenGupta, CA Parent, X Zhou, DN O'Dwyer, BB Moore
JCI Insight, 2022;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Clinical-like cryotherapy in acute knee arthritis of the knee improves inflammation signs, pain, joint swelling, and motor performance in mice
Authors: PATS Castro, GM Barbosa, DH Machanocke, RS Peres, TM Cunha, JE Cunha, FFB Oliveira, FS Ramalho, TL Russo, FQ Cunha, TF Salvini
PLoS ONE, 2022;17(1):e0261667.
Species: Mouse
Sample Types: Tissue Homogenates
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Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation
Authors: LK Billingham, JS Stoolman, K Vasan, AE Rodriguez, TA Poor, M Szibor, HT Jacobs, CR Reczek, A Rashidi, P Zhang, J Miska, NS Chandel
Nature Immunology, 2022;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Freshwater Clam Extract Mitigates Neuroinflammation and Amplifies Neurotrophic Activity of Glia: Insights from In Vitro Model of Neurodegenerative Pathomechanism
Authors: MS Lin, SM Chen, KF Hua, WJ Chen, CC Hsieh, CC Lin
Journal of Clinical Medicine, 2022;11(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
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IL-22 regulates inflammatory responses to agricultural dust-induced airway inflammation
Authors: A Ulu, S Sveiven, A Bilg, JV Velazquez, M Diaz, M Mukherjee, AG Yuil-Valde, S Kota, A Burr, A Najera, TM Nordgren
Toxicology and Applied Pharmacology, 2022;0(0):116044.
Species: Mouse
Sample Types: BALF
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Phosphatidylinositol 3-Kinase (PI3K) Orchestrates Aspergillus fumigatus-Induced Eosinophil Activation Independently of Canonical Toll-Like Receptor (TLR)/C-Type-Lectin Receptor (CLR) Signaling
Authors: A Dietschman, S Schruefer, S Westermann, F Henkel, K Castiglion, R Willebrand, J Adam, J Ruland, R Lang, DC Sheppard, J Esser-von-, D Radtke, S Krappmann, D Voehringer
MBio, 2022;0(0):e0123922.
Species: Mouse
Sample Types: Cell Culture Supernates
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A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling
Authors: SJ Matissek, M Karbalivan, W Han, A Boutilier, E Yzar-Garci, LL Kehoe, DS Gardner, A Hage, K Fleck, V Jeffers, R Rajsbaum, SF Elsawa
Oncotarget, 2022;13(0):944-959.
Species: Mouse
Sample Types: Cell Culture Supernates
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Cationic Polyethyleneimine (PEI)-Gold Nanocomposites Modulate Macrophage Activation and Reprogram Mouse Breast Triple-Negative MET-1 Tumor Immunological Microenvironment
Authors: V Mulens-Ari, A Nicolás-Bo, F Carn, F Gazeau
Pharmaceutics, 2022;14(10):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-kappaB Signaling
Authors: J Liu, L Shi, W Huang, Z Zheng, X Huang, Y Su
Mediators of Inflammation, 2022;2022(0):3441357.
Species: Mouse
Sample Types: Cell Lysates
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Acinetobacter quorum sensing contributes to inflammation-induced inhibition of orthopaedic implant osseointegration
Authors: H Choe, BS Hausman, KM Hujer, O Akkus, PN Rather, Z Lee, RA Bonomo, EM Greenfield
Oncogene, 2022;43(0):267-276.
Species: Mouse
Sample Types: Tissue Homogenates
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Extracellular matrix of early pulmonary fibrosis modifies the polarization of alveolar macrophage
Authors: Y Zhang, L Zhu, J Hong, C Chen
International immunopharmacology, 2022;111(0):109179.
Species: Mouse
Sample Types: Cell Culture Supernates
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Bacteria reduce flagellin synthesis to evade microglia-astrocyte-driven immunity in the brain
Authors: H Sun, X Wan, Y Fan, P Liu, Y Song, N Zhu, Z Duan, Q Wang, F Chen, C Zhou, Y Zheng, P Ding, F Liu, L Feng, KS Kim, L Wang
Cell Reports, 2022;40(1):111033.
Species: Mouse
Sample Types: Cell Culture Supernates
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Combinatorial microRNA Loading into Extracellular Vesicles for Increased Anti-Inflammatory Efficacy
Authors: AE Pottash, D Levy, A Jeyaram, L Kuo, SM Kronstadt, W Chao, SM Jay
Non-coding RNA, 2022;8(5):.
Species: Mouse
Sample Types: Plasma
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Consequences of the Lack of TNFR1 in Ouabain Response in the Hippocampus of C57BL/6J Mice
Authors: PF Kinoshita, AM Orellana, DZ Andreotti, GA de Souza, NP de Mello, L de Sá Lima, EM Kawamoto, C Scavone
Biomedicines, 2022;10(11):.
Species: Mouse
Sample Types: Serum
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In vitro and in vivo Characterization of Host-Pathogen Interactions of the L3881 Candida albicans Clinical Isolate
Authors: PHF Sucupira, TR Moura, ILS Gurgel, TTP Pereira, ACB Padovan, MM Teixeira, D Bahia, FM Soriani
Frontiers in Microbiology, 2022;13(0):901442.
Species: Mouse
Sample Types: Cell Culture Supernates
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Activation of the alpha7 Nicotinic Acetylcholine Receptor Prevents against Microglial-Induced Inflammation and Insulin Resistance in Hypothalamic Neuronal Cells
Authors: CLD Amaral, ÍCA Martins, ACC Veras, FM Simabuco, MG Ross, M Desai, LM Ignácio-So, M Milanski, AS Torsoni, MA Torsoni
Cells, 2022;11(14):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Smoking status impacts treatment efficacy in smoke-induced lung inflammation: A pre-clinical study
Authors: N Milad, M Pineault, F Tremblay, J Routhier, A Lechasseur, MJ Beaulieu, S Aubin, MC Morissette
Frontiers in Pharmacology, 2022;13(0):971238.
Species: Mouse
Sample Types: Cell Culture Supernatants
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Sirtuin 1 Induces Choroidal Neovascularization and Triggers Age-Related Macular Degeneration by Promoting LCN2 through SOX9 Deacetylation
Authors: S Zhao, Z Huang, H Jiang, J Xiu, L Zhang, Q Long, Y Yang, L Yu, L Lu, H Gu
Oncogene, 2022;2022(0):1671438.
Species: Mouse
Sample Types: Tissue Homogenates
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Neuroprotective effects of ex vivo-expanded regulatory T cells on trimethyltin-induced neurodegeneration in mice
Authors: SY Park, H Yang, M Ye, X Liu, I Shim, YT Chang, H Bae
Journal of Neuroinflammation, 2022;19(1):143.
Species: Mouse
Sample Types: Serum
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Z-DNA binding protein 1 mediates necroptotic and apoptotic cell death pathways in murine astrocytes following herpes simplex virus-1 infection
Authors: AM Jeffries, AJ Suptela, I Marriott
Journal of Neuroinflammation, 2022;19(1):109.
Species: Mouse
Sample Types: Cell Culture Supernates
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Sponges from Plasma Treated Cellulose Nanofibers Grafted with Poly(ethylene glycol)methyl Ether Methacrylate
Authors: I Chiulan, DM Panaitescu, A Serafim, ER Radu, G Ioni??, V R?di?oiu, AR Gabor, CA Nicolae, M Ghiurea, DD Baciu
Polymers, 2022;14(21):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Polyphenols-Rich Fraction from Annona muricata Linn. Leaves Attenuates Oxidative and Inflammatory Responses in Neutrophils, Macrophages, and Experimental Lung Injury
Authors: AL Saraiva, AB Justino, RR Franco, HCG Silva, FDS Arruda, SG Klein, MRN Celes, LR Goulart, FS Espindola
Pharmaceutics, 2022;14(6):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Electrical stimulation of the splenic nerve bundle ameliorates dextran sulfate sodium-induced colitis in mice
Authors: DJ Brinkman, T Simon, AS Ten Hove, K Zafeiropou, O Welting, PHP van Hamers, RA Willemze, AYFL Yim, C Verseijden, TBM Hakvoort, MD Luyer, MJ Vervoordel, P Blancou, WJ de Jonge
Journal of Neuroinflammation, 2022;19(1):155.
Species: Mouse
Sample Types: Cell Culture Supernates
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Lithocholic acid inhibits dendritic cell activation by reducing intracellular glutathione via TGR5 signaling
Authors: J Hu, Y Zhang, S Yi, C Wang, X Huang, S Pan, J Yang, G Yuan, S Tan, H Li
International journal of biological sciences, 2022;18(11):4545-4559.
Species: Mouse
Sample Types: Cell Culture Supernates
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Development of sulfonamide-based NLRP3 inhibitors: Further modifications and optimization through structure-activity relationship studies
Authors: Y Xu, Y Xu, H Blevins, C Guo, S Biby, XY Wang, C Wang, S Zhang
European Journal of Medicinal Chemistry, 2022;238(0):114468.
Species: Mouse
Sample Types: Cell Culture Supernates
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The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways
Authors: M Pereira, DF Durso, CE Bryant, EA Kurt-Jones, N Silverman, DT Golenbock, RT Gazzinelli
Cell Reports, 2022;40(7):111225.
Species: Mouse
Sample Types: Cell Culture Supernates
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Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation
Authors: Y Ni, GH Wu, JJ Cai, R Zhang, Y Zheng, JQ Liu, XH Yang, X Yang, Y Shen, JM Lai, XM Ye, SJ Mo
International journal of biological sciences, 2022;18(13):5168-5184.
Species: Mouse
Sample Types: Cell Culture Supernates
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Small Molecules as Toll-like Receptor 4 Modulators Drug and In-House Computational Repurposing
Authors: L Pérez-Regi, J Guzmán-Cal, N Oberhauser, C Punzón, B Balogh, JR Pedro, E Falomir, A Nurisso, P Mátyus, JC Menéndez, B de Andrés, M Fresno, S Martín-San
Biomedicines, 2022;10(9):.
Species: Mouse
Sample Types: Cell Culture Supernates
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A Novel Approach to Vaccine Development: Concomitant Pathogen Inactivation and Host Immune Stimulation by Peroxynitrite
Authors: S Rotem, E Bar-Haim, U Elia, H Cohen, S Lazar, O Cohen, T Chitlaru, Y Gal
Vaccines, 2022;10(10):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus
Authors: A Doni, R Parente, I Laface, E Magrini, C Cunha, FS Colombo, JF Lacerda, A Campos, SN Mapelli, F Petroni, R Porte, T Schorn, A Inforzato, T Mercier, K Lagrou, J Maertens, JD Lambris, B Bottazzi, C Garlanda, M Botto, A Carvalho, A Mantovani
Nature Communications, 2021;12(1):3739.
Species: Mouse
Sample Types: Cell Culture Supernates
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Role of the inhibitor of serine peptidase 2 (ISP2) of Trypanosoma brucei rhodesiense in parasite virulence and modulation of the inflammatory responses of the host
Authors: DJ Levy, A Goundry, RSS Laires, TFR Costa, CM Novo, DJ Grab, JC Mottram, APCA Lima
PloS Neglected Tropical Diseases, 2021;15(6):e0009526.
Species: Mouse
Sample Types: Cell Culture Supernates
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4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice
Authors: LA Rojas-Coló, PK Dash, FA Morales-Ví, M Lebrón-Dáv, PA Ferchmin, JB Redell, G Maldonado-, WI Vélez-Torr
Journal of Neuroinflammation, 2021;18(1):95.
Species: Mouse
Sample Types: Plasma
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Ligase Pellino3 Regulates Macrophage Action and Survival in Response to VSV Infection in RIG-I-Dependent Path
Authors: P Reniewicz, A Kula, E Makuch, M Ochnik, T Lipi?ski, J Siednienko
Oxidative Medicine and Cellular Longevity, 2021;2021(0):6668463.
Species: Mouse
Sample Types: Cell Culture Supernates
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A high docosahexaenoic acid diet alters lung inflammation and recovery following repetitive exposure to aqueous organic dust extracts: Role of DHA in repetitive organic dust exposure
Authors: A Ulu, A Burr, AJ Heires, J Pavlik, T Larsen, PA Perez, C Bravo, NV DiPatrizio, M Baack, DJ Romberger, TM Nordgren
The Journal of nutritional biochemistry, 2021;0(0):108797.
Species: Mouse
Sample Types: BALF
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In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis
Authors: SE Huang, E Sulistyowa, YY Chao, BN Wu, ZK Dai, JH Hsu, JL Yeh
Biomedicines, 2021;9(6):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Oxidant-induced epithelial alarmin pathway mediates lung inflammation and functional decline following ultrafine carbon and ozone inhalation co-exposure
Authors: N Majumder, WT Goldsmith, VK Kodali, M Velayutham, SA Friend, VV Khramtsov, TR Nurkiewicz, A Erdely, PC Zeidler-Er, V Castranova, JR Harkema, EE Kelley, S Hussain
Redox Biology, 2021;46(0):102092.
Species: Mouse
Sample Types: BALF
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Resveratrol-Loaded Lipid-Core Nanocapsules Modulate Acute Lung Inflammation and Oxidative Imbalance Induced by LPS in Mice
Authors: MTP de Oliveir, DS Coutinho, SS Guterres, AR Pohlmann, PMRE Silva, MA Martins, A Bernardi
Pharmaceutics, 2021;13(5):.
Species: Mouse
Sample Types: Tissue Homogenates
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Sambucus nigra: A traditional medicine effective in reducing inflammation in mice
Authors: JR Santin, L Benvenutti, MF Broering, R Nunes, FC Goldoni, YBK Patel, JA de Souza, MAT Kopp, P de Souza, RCV da Silva, MVD Pastor, AB de Souza, LD Testoni, AG Couto, TMB Bresolin, NLM Quintão
Journal of ethnopharmacology, 2021;283(0):114736.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation
Authors: CC Lin, YR Shen, CC Chang, XY Guo, YY Young, TY Lai, IS Yu, CY Lee, TH Chuang, HY Tsai, LC Hsu
Nature Communications, 2021;12(1):3878.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Peroxiredoxin AhpC1 protects Pseudomonas aeruginosa against the inflammatory oxidative burst and confers virulence
Authors: LS Rocha, BPD Silva, TML Correia, RPD Silva, DA Meireles, R Pereira, LES Netto, FC Meotti, RF Queiroz
Redox Biology, 2021;46(0):102075.
Species: Mouse
Sample Types: Serum
-
Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs
Authors: L Benvenutti, R Nunes, I Venturi, SA Ramos, MF Broering, FC Goldoni, SE Pavan, MVD Pastor, A Malheiros, NLM Quintão, ES Fernandes, JR Santin
Journal of Immunology Research, 2021;2021(0):9957451.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Acute neuroinflammation, sickness behavior and working memory responses to acute systemic LPS challenge following noradrenergic lesion in mice
Authors: E O'Neill, ÉW Griffin, R O'Sullivan, C Murray, L Ryan, J Yssel, A Harkin, C Cunningham
Brain, Behavior, and Immunity, 2021;94(0):357-368.
Species: Mouse
Sample Types: Serum
-
DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization
Authors: L Liu, Y Wu, B Wang, Y Jiang, L Lin, X Li, S Yang
Cell Death & Disease, 2021;12(6):500.
Species: Mouse
Sample Types: Serum
-
Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling
Authors: L Gu, R Surolia, JL Larson-Cas, C He, D Davis, J Kang, VB Antony, AB Carter
Cell Death and Differentiation, 2021;0(0):.
Species: Mouse
Sample Types: BALF
-
Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation
Authors: F Virga, F Cappelless, B Stijlemans, AT Henze, R Trotta, J Van Audena, AS Mirchandan, MA Sanchez-Ga, J Vandewalle, F Orso, C Riera-Domi, A Griffa, C Ivan, E Smits, D Laoui, F Martelli, L Langouche, G Van den Be, O Feron, B Ghesquière, H Prenen, C Libert, SR Walmsley, C Corbet, JA Van Ginder, M Ivan, D Taverna, M Mazzone
Science Advances, 2021;7(19):.
Species: Mouse
Sample Types: Plasma
-
Acute Inflammatory Response in Osteoporotic Fracture Healing Augmented with Mechanical Stimulation is Regulated In Vivo through the p38-MAPK Pathway
Authors: SKH Chow, C Cui, KYK Cheng, YN Chim, J Wang, CHW Wong, KW Ng, RMY Wong, WH Cheung
International Journal of Molecular Sciences, 2021;22(16):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Selective Expression of a SNARE-Cleaving Protease in Peripheral Sensory Neurons Attenuates Pain-Related Gene Transcription and Neuropeptide Release
Authors: W Wang, M Kong, Y Dou, S Xue, Y Liu, Y Zhang, W Chen, Y Li, X Dai, J Meng, J Wang
International Journal of Molecular Sciences, 2021;22(16):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2
Authors: WJ Melvin, CO Audu, FM Davis, SB Sharma, A Joshi, A DenDekker, S Wolf, E Barrett, K Mangum, X Zhou, M Bame, A Ruan, A Obi, SL Kunkel, BB Moore, KA Gallagher
Proceedings of the National Academy of Sciences of the United States of America, 2021;118(38):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition
Authors: AM Ghanim, S Rezq, TS Ibrahim, DG Romero, H Kothayer
European Journal of Medicinal Chemistry, 2021;219(0):113457.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia
Authors: J Wu, N Chen, Y Liu, G Godlewski, HJ Kaplan, SH Shrader, ZH Song, H Shao
PLoS ONE, 2021;16(5):e0251677.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Presence and activation of pro-inflammatory macrophages are associated with CRYAB expression in vitro and after peripheral nerve injury
Authors: EF Lim, V Hoghooghi, KM Hagen, K Kapoor, A Frederick, TM Finlay, SS Ousman
Journal of Neuroinflammation, 2021;18(1):82.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity
Authors: G Cavalli, IW Tengesdal, M Gresnigt, T Nemkov, RJW Arts, J Domínguez-, R Molteni, D Stefanoni, E Cantoni, L Cassina, S Giugliano, K Schraa, TS Mills, EM Pietras, EZ Eisenmenss, L Dagna, A Boletta, A D'Alessand, LAB Joosten, MG Netea, CA Dinarello
Cell Reports, 2021;35(1):108955.
Species: Mouse
Sample Types: Tissue Homogenates
-
Pra-C exerts analgesic effect through inhibiting microglial activation in anterior cingulate cortex in complete Freund's adjuvant-induced mouse model
Authors: DJ Su, LF Li, SY Wang, Q Yang, YJ Wu, MG Zhao, L Yang
Molecular pain, 2021;17(0):1744806921990.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Itaconate confers tolerance to late NLRP3 inflammasome activation
Authors: M Bambouskov, L Potuckova, T Paulenda, M Kerndl, DA Mogilenko, K Lizotte, A Swain, S Hayes, RD Sheldon, H Kim, U Kapadnis, AE Ellis, C Isaguirre, S Burdess, A Laha, GK Amarasingh, V Chubukov, TP Roddy, MS Diamond, RG Jones, DM Simons, MN Artyomov
Cell Reports, 2021;34(10):108756.
Species: Mouse
Sample Types: Peritoneal Fluid
-
Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis
Authors: K Phulphagar, LI Kühn, S Ebner, A Frauenstei, JJ Swietlik, J Rieckmann, F Meissner
Cell Reports, 2021;34(10):108826.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-Inflammatory Effects of Antarctic Lichen Umbilicaria antarctica Methanol Extract in Lipopolysaccharide-Stimulated RAW 264.7 Macrophage Cells and Zebrafish Model
Authors: JM Hong, JE Kim, SK Min, KH Kim, SJ Han, JH Yim, H Park, JH Kim, IC Kim
BioMed Research International, 2021;2021(0):8812090.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype
Authors: J Lora, G Weskamp, TM Li, T Maretzky, DTN Shola, S Monette, SF Lichtentha, TT Lu, C Yang, CP Blobel
The Journal of Biological Chemistry, 2021;0(0):100733.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Clostridioides difficile spores stimulate inflammatory cytokine responses and induce cytotoxicity in macrophages
Authors: PJ Chiu, J Rathod, YP Hong, PJ Tsai, YP Hung, WC Ko, JW Chen, D Paredes-Sa, IH Huang
Anaerobe, 2021;70(0):102381.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-&kappaB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways
Authors: N Lee, YJ Heo, SE Choi, JY Jeon, SJ Han, DJ Kim, Y Kang, KW Lee, HJ Kim
Journal of Immunology Research, 2021;2021(0):9944880.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The impact of damage-associated molecules released from canine tumor cells on gene expression in macrophages
Authors: S Eto, H Yanai, S Hangai, D Kato, R Nishimura, T Nakagawa
Scientific Reports, 2021;11(1):8525.
Species: Canine
Sample Types: Cell Culture Supernates
-
Hepatoprotective Effect of Mixture of Dipropyl Polysulfides in Concanavalin A-Induced Hepatitis
Authors: D Arsenijevi, B Stojanovic, J Milovanovi, A Arsenijevi, M Simic, M Pergal, I Kodranov, O Cvetkovic, D Vojvodic, E Ristanovic, D Manojlovic, M Milovanovi, N Arsenijevi
Nutrients, 2021;13(3):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Discovery and characterization of small molecule inhibitors of NLRP3 and NLRC4 inflammasomes
Authors: M Sebastian-, H Wu, M Al Rahim, R Sanchez, K Kumar, RJ De Vita, GM Pasinetti
The Journal of Biological Chemistry, 2021;0(0):100597.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Signaling through Syk or CARD9 Mediates Species-Specific Anti-Candida Protection in Bone Marrow Chimeric Mice
Authors: E Zajta, K Csonka, A Tóth, L Tiszlavicz, T Németh, A Orosz, Á Novák, M Csikós, C Vágvölgyi, A Mócsai, A Gácser
MBio, 2021;12(4):e0160821.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Fish Oil Enriched in EPA, but Not in DHA, Reverses the Metabolic Syndrome and Adipocyte Dysfunction Induced by a High-Fat Diet
Authors: RDC da Cunha d, JJ Simão, VSD Silva, TM Farias, MM Cruz, VJ Antraco, L Armelin-Co, MI Alonso-Val
Nutrients, 2021;13(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages
Authors: JK Dowling, R Afzal, LJ Gearing, MP Cervantes-, S Annett, GM Davis, C De Santi, N Assmann, K Dettmer, DJ Gough, GR Bantug, FI Hamid, FK Nally, CP Duffy, AL Gorman, AM Liddicoat, EC Lavelle, C Hess, PJ Oefner, DK Finlay, GP Davey, T Robson, AM Curtis, PJ Hertzog, BRG Williams, CE McCoy
Nature Communications, 2021;12(1):1460.
Species: Mouse
Sample Types: Cell Culture Supernates
-
&alpha-Phellandrene exhibits antinociceptive and tumor-reducing effects in a mouse model of oncologic pain
Authors: FR Pinheiro-N, EM Lopes, BT Acha, LDS Gomes, WA Dias, ACD Reis Filho, BS Leal, DCDN Rodrigues, JDN Silva, D Dittz, PMP Ferreira, FRC Almeida
Toxicology and Applied Pharmacology, 2021;418(0):115497.
Species: Mouse
Sample Types: Serum
-
Encapsulation of a CpG oligonucleotide in cationic liposomes enhances its local antitumor activity following pulmonary delivery in a murine model of metastatic lung cancer
Authors: C Loira-Past, K Vanvarenbe, B Ucakar, M Machado Fr, A Staub, M Lemaire, JC Renauld, R Vanbever
International journal of pharmaceutics, 2021;600(0):120504.
Species: Mouse
Sample Types: Serum
-
Sevoflurane preconditioning activates HGF/Met-mediated autophagy to attenuate hepatic ischemia-reperfusion injury in mice
Authors: X Xiao, D Liu, S Chen, X Li, M Ge, W Huang
Cellular Signalling, 2021;0(0):109966.
Species: Mouse
Sample Types: Tissue Homogenates
-
Probiotic and Functional Properties of Limosilactobacillus reuteri INIA P572
Authors: P Diez-Echav, I Martín-Cab, J Garrido-Me, S Langa, T Vezza, JM Landete, L Hidalgo-Ga, F Algieri, MJ Mayer, A Narbad, A García-Laf, M Medina, A Rodríguez-, ME Rodríguez-, J Gálvez, JL Arqués
Nutrients, 2021;13(6):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Hypoxia-Induced S100A8 Expression Activates Microglial Inflammation and Promotes Neuronal Apoptosis
Authors: JS Ha, HR Choi, IS Kim, EA Kim, SW Cho, SJ Yang
International Journal of Molecular Sciences, 2021;22(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus
Authors: A Amend, N Wickli, AL Schäfer, DTL Sprenger, RA Manz, RE Voll, N Chevalier
International Journal of Molecular Sciences, 2021;22(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Sex-dependent differences in the gut microbiota following chronic nasal inflammation in adult mice
Authors: Y Mishima, T Osaki, A Shimada, S Kamiya, S Hasegawa-I
Scientific Reports, 2021;11(1):4640.
Species: Mouse
Sample Types: Serum
-
All-trans-retinoic acid ameliorates atherosclerosis, promotes perivascular adipose tissue browning, and increases adiponectin production in Apo-E mice
Authors: M Kalisz, M Chmielowsk, L Marty?ska, A Doma?ska, W Bik, A Litwiniuk
Scientific Reports, 2021;11(1):4451.
Species: Mouse
Sample Types: Tissue Homogenates
-
Combined Effects of Exercise and Phytoanabolic Extracts in Castrated Male and Female Mice
Authors: JP Martins, LC Silva, MS Nunes, G Rübensam, JR Oliveira, RBM Silva, MM Campos
Nutrients, 2021;13(4):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Hydroxyapatite-Coated SPIONs and Their Influence on Cytokine Release
Authors: B Friedrich, JP Auger, S Dutz, I Cicha, E Schreiber, J Band, AR Boccacccin, G Krönke, C Alexiou, R Tietze
International Journal of Molecular Sciences, 2021;22(8):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS
Authors: M Najibi, HH Honwad, JA Moreau, SM Becker, JE Irazoqui
Autophagy, 2021;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Thymoquinone, a Dietary Bioactive Compound, Exerts Anti-Inflammatory Effects in Colitis by Stimulating Expression of the Colonic Epithelial PPAR-&gamma Transcription Factor
Authors: B Venkataram, S Almarzooqi, V Raj, AT Alhassani, AS Alhassani, KJ Ahmed, VS Subramania, SK Ojha, S Attoub, TE Adrian, SB Subramanya
Nutrients, 2021;13(4):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction
Authors: R Peruzzo, S Corrà, R Costa, M Brischigli, T Varanita, L Biasutto, C Rampazzo, D Ghezzi, L Leanza, M Zoratti, M Zeviani, C De Pittà, C Viscomi, R Costa, I Szabò
Nature Communications, 2021;12(1):2103.
Species: Mouse
Sample Types: Plasma
-
Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients
Authors: V Farré-Alin, A Palomino-A, P Narros-Fer, AB Lopez-Rodr, C Decouty-Pe, A Muñoz-Mont, J Zamorano-F, B Mansilla-F, J Giner-Garc, P García-Fei, M Sáez-Alegr, AJ Palpán-Flo, JM Roda-Frade, CS Carabias, JM Rosa, B Civantos-M, S Yus-Teruel, L Gandía, A Lagares, BJ Hernández-, J Egea
Biomedicines, 2021;9(6):.
Species: Mouse
Sample Types: Cell Cultue Supernates
-
Water-soluble polysaccharides from Pleurotus eryngii fruiting bodies, their activity and affinity for Toll-like receptor 2 and dectin-1
Authors: CF Ellefsen, CW Wold, AL Wilkins, F Rise, ABC Samuelsen
Carbohydrate polymers, 2021;264(0):117991.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo
Authors: S Estfanous, K Krause, MNK Anne, M Eltobgy, K Caution, A Abu Khweek, K Hamilton, A Badr, K Daily, C Carafice, D Baetzhold, X Zhang, T Li, H Wen, MA Gavrilin, H Haffez, S Soror, AO Amer
Scientific Reports, 2021;11(1):855.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gene expression patterns associated with Leishmania panamensis infection in macrophages from BALB/c and C57BL/6 mice
Authors: CM Restrepo, A Llanes, L Herrera, E Ellis, R Lleonart, PL Fernández
PloS Neglected Tropical Diseases, 2021;15(2):e0009225.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling
Authors: J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li
Cell Reports, 2021;36(12):109726.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cardiolipin-mediated PPAR&gamma S112 phosphorylation impairs IL-10 production and inflammation resolution during bacterial pneumonia
Authors: M Garg, S Johri, S Sagar, A Mundhada, A Agrawal, P Ray, K Chakrabort
Cell Reports, 2021;34(6):108736.
Species: Mouse
Sample Types: Tissue Homogenates
-
Intense Acute Swimming Induces Delayed-Onset Muscle Soreness Dependent on Spinal Cord Neuroinflammation
Authors: SM Borghi, SKD Bussulo, FA Pinho-Ribe, V Fattori, TT Carvalho, FS Rasquel-Ol, TH Zaninelli, CR Ferraz, AMB Casella, FQ Cunha, TM Cunha, R Casagrande, WA Verri
Frontiers in Pharmacology, 2021;12(0):734091.
Species: Mouse
Sample Types: Tissue Homogenates
-
PDE9 Inhibitor PF-04447943 Attenuates DSS-Induced Colitis by Suppressing Oxidative Stress, Inflammation, and Regulating T-Cell Polarization
Authors: MN Rana, J Lu, E Xue, J Ruan, Y Liu, L Zhang, R Dhar, Y Li, Z Hu, J Zhou, W Ma, H Tang
Frontiers in Pharmacology, 2021;12(0):643215.
Species: Mouse
Sample Types: Tissue Homogenates
-
Oxidized carbon black nanoparticles induce endothelial damage through C-X-C chemokine receptor 3-mediated pathway
Authors: N Majumder, M Velayutham, D Bitounis, VK Kodali, MH Hasan Mazu, J Amedro, VV Khramtsov, A Erdely, T Nurkiewicz, P Demokritou, EE Kelley, S Hussain
Redox Biology, 2021;47(0):102161.
Species: Mouse
Sample Types: BALF
-
Pertactin contributes to shedding and transmission of Bordetella bronchiseptica
Authors: L Ma, KK Dewan, DL Taylor-Mul, SM Wagner, B Linz, I Rivera, Y Su, AD Caulfield, U Blas-Macha, ET Harvill
PloS Pathogens, 2021;17(8):e1009735.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NLRP3 Triggers Attenuate Lipocalin-2 Expression Independent with Inflammasome Activation
Authors: H Ahn, G Lee, J Kim, J Park, SG Kang, SI Yoon, E Lee, GS Lee
Cells, 2021;10(7):.
Species: Mouse
Sample Types: Cell Lysates
-
Endangered Lymphocytes: The Effects of Alloxan and Streptozotocin on Immune Cells in Type 1 Induced Diabetes
Authors: LAD Queiroz, JB Assis, JPT Guimarães, ESA Sousa, AC Milhomem, KKS Sunahara, A Sá-Nunes, JO Martins
Mediators of Inflammation, 2021;2021(0):9940009.
Species: Mouse
Sample Types: Tissue Homogenates
-
Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life
Authors: MG Granja, LP Alves, M Leardini-T, ME Saul, LC Bortoni, FM de Moraes, EC Ferreira, BPT de Moraes, VZ da Silva, AFR Dos Santos, AR Silva, CF Gonçalves-, V Bambini-Ju, AS Weyrich, MT Rondina, GA Zimmerman, HC de Castro-
Journal of Neuroinflammation, 2021;18(1):60.
Species: Mouse
Sample Types: Tissue Homogenates
-
Activation of Cph1 causes �(1,3)-glucan unmasking in Candida albicans and attenuates virulence in mice in a neutrophil-dependent manner
Authors: AS Wagner, TJ Hancock, SW Lumsdaine, SJ Kauffman, MM Mangrum, EK Phillips, TE Sparer, TB Reynolds
PloS Pathogens, 2021;17(8):e1009839.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Geographic differences in gut microbiota composition impact susceptibility to enteric infection
Authors: AM Porras, Q Shi, H Zhou, R Callahan, G Montenegro, N Solomons, IL Brito
Cell Reports, 2021;36(4):109457.
Species: Mouse
Sample Types: Tissue Supernates
-
Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation
Authors: H Shokirova, T Inomata, T Saitoh, J Zhu, K Fujio, Y Okumura, A Yanagawa, K Fujimoto, J Sung, A Eguchi, M Miura, K Nagino, K Hirosawa, M Kuwahara, Y Akasaki, H Nagase, A Murakami
Scientific Reports, 2021;11(1):8647.
Species: Mouse
Sample Types: Tissue Homogenates
-
Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway
Authors: YK Wu, ZN Ren, SL Zhu, YZ Wu, G Wang, H Zhang, W Chen, Z He, XL Ye, QX Zhai
Acta pharmacologica Sinica, 2021;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Limited role of the spleen in a mouse model of trained immunity: Impact on neutrophilia
Authors: AV Ferreira, RF Uijen, O Bulut, MI de Jonge, J Domínguez-, MG Netea
Journal of leukocyte biology, 2021;0(0):.
Species: Mouse
Sample Types: Serum
-
Bifidobacterium breve Exopolysaccharide Blocks Dendritic Cell Maturation and Activation of CD4+ T Cells
Authors: A Hickey, P Stamou, S Udayan, A Ramón-Vázq, M Esteban-To, F Bottacini, JA Woznicki, O Hughes, S Melgar, M Ventura, D Van Sinder, V Rossini, K Nally
Frontiers in Microbiology, 2021;12(0):653587.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Synergistic inhibitory effects of the oxyresveratrol and dacarbazine combination against melanoma cells
Authors: SG Lee, DG Lee, YH Joo, N Chung
Oncology Letters, 2021;22(3):667.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gymnema inodorum (Lour.) Decne. Extract Alleviates Oxidative Stress and Inflammatory Mediators Produced by RAW264.7 Macrophages
Authors: B Dunkhuntho, C Talabnin, M Murphy, K Thumanu, P Sittisart, G Eumkeb
Oxidative Medicine and Cellular Longevity, 2021;2021(0):8658314.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Remote effects and biodistribution of pulmonary instilled silver nanoparticles in mice
Authors: Z Ferdous, S Al-Salam, P Yuvaraju, BH Ali, A Nemmar
NanoImpact, 2021;22(0):100310.
Species: Mouse
Sample Types: Tissue Homogenates
-
Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI)
Authors: CK Lin, TH Huang, CT Yang, CS Shi
PLoS ONE, 2021;16(3):e0248959.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Central and peripheral effects of environmental enrichment in a mouse model of arthritis
Authors: M Estrázulas, RDS Freitas, ET Käfer, APA Dagnino, MM Campos
International immunopharmacology, 2021;0(0):108386.
Species: Mouse
Sample Types: Serum
-
PI3K/ NF-kappaB-dependent TNF-alpha and HDAC activities facilitate LPS-induced RGS10 suppression in pulmonary macrophages
Authors: F Almutairi, SL Tucker, D Sarr, B Rada
Cellular Signalling, 2021;86(0):110099.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Expression of IL-20 Receptor Subunit beta Is Linked to EAE Neuropathology and CNS Neuroinflammation
Authors: JR Dayton, Y Yuan, LP Pacumio, BG Dorflinger, SC Yoo, MJ Olson, SI Hernández-, MM McMahon, L Cruz-Oreng
Frontiers in Cellular Neuroscience, 2021;15(0):683687.
Species: Mouse
Sample Types: Tissue Homogenates
-
CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet-Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling
Authors: KC Ngamsri, RA Putri, C Jans, K Schindler, A Fuhr, Y Zhang, J Gamper-Tsi, S Ehnert, FM Konrad
International Journal of Molecular Sciences, 2021;22(24):.
Species: Mouse
Sample Types: Plasma
-
Therapeutic Effects of Fenofibrate Nano-Emulsion Eye Drops on Retinal Vascular Leakage and Neovascularization
Authors: L Huang, W Liang, K Zhou, RA Wassel, ZD Ridge, JX Ma, B Wang
Biology, 2021;10(12):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis
Authors: BY Lee, EKJ Hogg, CR Below, A Kononov, A Blanco-Gom, F Heider, J Xu, C Hutton, X Zhang, T Scheidt, K Beattie, A Lamarca, M McNamara, JW Valle, C Jørgensen
Nature Communications, 2021;12(1):7336.
Species: Mouse
Sample Types: Tissue Homogenates
-
Restraint of Fumarate Accrual by HIF-1alpha Preserves miR-27a-Mediated Limitation of Interleukin 10 during Infection of Macrophages by Histoplasma capsulatum
Authors: HM Evans, DF Schultz, AJ Boiman, MC McKell, JE Qualls, GS Deepe
MBio, 2021;0(0):e0271021.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Signalling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1alpha in lipopolysaccharide-activated macrophages
Authors: NC Williams, DG Ryan, ASH Costa, EL Mills, MP Jedrychows, SM Cloonan, C Frezza, LA O'Neill
The Journal of Biological Chemistry, 2021;0(0):101501.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells
Authors: MC Kiritsy, K McCann, D Mott, SM Holland, SM Behar, CM Sassetti, AJ Olive
Elife, 2021;10(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-gamma production by CD25+Foxp3- T cells
Authors: J Tomala, P Weberova, B Tomalova, Z Jiraskova, L Sivak, J Kovarova, M Kovar
Elife, 2021;10(0):.
Species: Mouse
Sample Types: Serum
-
Ephedrine ameliorates chronic obstructive pulmonary disease (COPD) through restraining endoplasmic reticulum (ER) stress in vitro and in vivo
Authors: HL Wang, FQ Chen, LJ Wu
International immunopharmacology, 2021;103(0):107842.
Species: Mouse
Sample Types: BALF
-
The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages
Authors: KKL Wu, K Long, H Lin, PMF Siu, RLC Hoo, D Ye, A Xu, KKY Cheng
Nature Communications, 2021;12(1):6637.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cooling and Sterile Inflammation in an Oxygen-Glucose-Deprivation/Reperfusion Injury Model in BV-2 Microglia
Authors: J Lücht, N Rolfs, SJ Wowro, F Berger, KRL Schmitt, G Tong
Mediators of Inflammation, 2021;2021(0):8906561.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Secretory autophagy machinery and vesicular trafficking are involved in HMGB1 secretion
Authors: YH Kim, MS Kwak, B Lee, JM Shin, S Aum, IH Park, MG Lee, JS Shin
Autophagy, 2020;0(0):1-18.
Species: Mouse
Sample Types: Cell Culture Supernates
-
STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1&beta expression
Authors: JJ Balic, H Albargy, K Luu, FJ Kirby, WSN Jayasekara, F Mansell, DJ Garama, D De Nardo, N Baschuk, C Louis, F Humphries, K Fitzgerald, E Latz, DJ Gough, A Mansell
Nat Commun, 2020;11(1):3816.
Species: Mouse
Sample Types: Cell Lysates
-
The role of uncoupling protein 2 in macrophages and its impact on obesity-induced adipose tissue inflammation and insulin resistance
Authors: XAMH van Dieren, T Sancerni, MC Alves-Guer, R Stienstra
J Biol Chem, 2020;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Exopolysaccharide of Lactobacillus fermentum UCO-979C Is Partially Involved in Its Immunomodulatory Effect and Its Ability to Improve the Resistance against Helicobacter pylori Infection
Authors: V Garcia-Cas, G Marcial, L Albarracín, M Tomokiyo, P Clua, H Takahashi, H Kitazawa, A Garcia-Can, J Villena
Microorganisms, 2020;8(4):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cystatin C Plays a Sex-Dependent Detrimental Role in Experimental Autoimmune Encephalomyelitis
Authors: V Hoghooghi, AL Palmer, A Frederick, Y Jiang, JE Merkens, A Balakrishn, TM Finlay, A Grubb, E Levy, P Gordon, FR Jirik, MD Nguyen, C Schuurmans, F Visser, SE Dunn, SS Ousman
Cell Rep, 2020;33(1):108236.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Herbal Combinational Medication of Glycyrrhiza glabra, Agastache rugosa Containing Glycyrrhizic Acid, Tilianin Inhibits Neutrophilic Lung Inflammation by Affecting CXCL2, Interleukin-17/STAT3 Signal Pathways in a Murine Model of COPD
Authors: SH Kim, JH Hong, WK Yang, JH Geum, HR Kim, SY Choi, YM Kang, HJ An, YC Lee
Nutrients, 2020;12(4):.
Species: Mouse
Sample Types: BALF
-
Glycogen Metabolism Supports Early Glycolytic Reprogramming and Activation in Dendritic Cells in Response to Both TLR and Syk-Dependent CLR Agonists
Authors: KD Curtis, PR Smith, HW Despres, JP Snyder, TC Hogan, PD Rodriguez, E Amiel
Cells, 2020;9(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Abrogation of type-I interferon signalling alters the microglial response to A&beta1-42
Authors: Z Moore, F Mobilio, FR Walker, JM Taylor, PJ Crack
Scientific Reports, 2020;10(1):3153.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Recombinant Myxoma Virus-Derived Immune Modulator M-T7 Accelerates Cutaneous Wound Healing and Improves Tissue Remodeling
Authors: JR Yaron, L Zhang, Q Guo, EA Awo, M Burgin, LN Schutz, N Zhang, J Kilbourne, J Daggett-Vo, KM Lowe, AR Lucas
Pharmaceutics, 2020;12(11):.
-
Nucleic Acid-Sensing Toll-Like Receptors Play a Dominant Role in Innate Immune Recognition of Pneumococci
Authors: A Famà, A Midiri, G Mancuso, C Biondo, G Lentini, R Galbo, MM Giardina, GV De Gaetano, L Romeo, G Teti, C Beninati
MBio, 2020;11(2):.
Species: Mouse
Sample Types: Tissue Lysates
-
Peptidorhamnomannan from Lomentospora prolificans modulates the inflammatory response in macrophages infected with Candida albicans
Authors: MIDDS Xisto, SS Santos, L Rossato, FSY Yoshikawa, RMT Haido, SR de Almeida, E Barreto-Be
BMC Microbiol., 2020;20(1):245.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response
Authors: S Lee, S Kim, HY Kang, HR Lim, Y Kwon, M Jo, YM Jeon, SR Kim, K Kim, CM Ha, S Lee, HJ Kim
J Neuroinflammation, 2020;17(1):299.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis
Authors: JC DuBois, AK Ray, P Davies, B Shafit-Zag
J Neuroinflammation, 2020;17(1):324.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Olive Leaf Extract, from Olea europaea L., Reduces Palmitate-Induced Inflammation via Regulation of Murine Macrophages Polarization
Authors: P De Cicco, M Maisto, GC Tenore, A Ianaro
Nutrients, 2020;12(12):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dapagliflozin Does Not Modulate Atherosclerosis in Mice with Insulin Resistance
Authors: A Taberner-C, Á Vinué, A Herrero-Ce, M Aguilar-Ba, JT Real, DJ Burks, S Martínez-H, H González-N
International Journal of Molecular Sciences, 2020;21(23):.
Species: Mouse
Sample Types: Plasma
-
Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice
Authors: J Wang, C Ortiz, L Fontenot, R Mukhopadhy, Y Xie, IKM Law, DQ Shih, SA Mattai, Z Li, HW Koon
Sci Rep, 2020;10(1):12785.
Species: Mouse
Sample Types: Whole Cells
-
Increased Uptake of Silica Nanoparticles in Inflamed Macrophages but Not upon Co-Exposure to Micron-Sized Particles
Authors: E Susnik, P Taladriz-B, B Drasler, S Balog, A Petri-Fink, B Rothen-Rut
Cells, 2020;9(9):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer's Disease Transgenic Mouse Model
Authors: M Sohrabi, AM Floden, GD Manocha, MG Klug, CK Combs
Front Cell Neurosci, 2020;14(0):200.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages
Authors: K Maruyama, H Kidoya, N Takemura, E Sugisawa, O Takeuchi, T Kondo, MMA Eid, H Tanaka, MM Martino, N Takakura, Y Takayama, S Akira, A Vandenbon, Y Kumagai
Cell Rep, 2020;32(2):107906.
Species: Mouse
Sample Types: Cell Lysates
-
Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Candida Species
Authors: PE Negoro, S Xu, Z Dagher, A Hopke, JL Reedy, MB Feldman, NS Khan, AL Viens, NJ Alexander, NJ Atallah, AK Scherer, RA Dutko, J Jeffery, JF Kernien, JS Fites, JE Nett, BS Klein, JM Vyas, D Irimia, DB Sykes, MK Mansour
MBio, 2020;11(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Role of MKP-5 in Adipocyte-Macrophage Interactions during Obesity
Authors: Y Lu, J Ma, J Zhao, Z Song, C Zhou, X Liu, W Teng, W Wang, Q Zhang, W Yan, P Jiao
Obes Facts, 2020;0(0):1-16.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Abnormal Cannabidiol Affects Production of Pro-Inflammatory Mediators and Astrocyte Wound Closure in Primary Astrocytic-Microglial Cocultures
Authors: J Cardinal v, T Hohmann, F Dehghani
Molecules, 2020;25(3):.
Species: Mouse
Sample Types: Cell Culture Super
-
Neutrophils do not impact viral load or the peak of disease severity during RSV infection
Authors: F Kirsebom, C Michalaki, M Agueda-Oya, C Johansson
Sci Rep, 2020;10(1):1110.
Species: Mouse
Sample Types: Tissue Homogenates
-
Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation
Authors: HI Muendlein, J Sarhan, BC Liu, WM Connolly, SA Schworer, I Smirnova, AY Tang, V Ilyukha, J Pietruska, S Tahmasebi, N Sonenberg, A Degterev, A Poltorak
Cell Rep, 2020;30(3):699-713.e4.
Species: Mouse
Sample Types: Cell Culture Media
-
Distinct iron homeostasis in C57BL/6 and Balb/c mouse strains
Authors: P Saha, X Xiao, Y Li, RM Golonka, AA Abokor, BS Yeoh, M Vijay-Kuma
Physiol Rep, 2020;8(9):e14441.
Species: Mouse
Sample Types: Serum
-
Neosaxitoxin Inhibits the Expression of Inflammation Markers of the M1 Phenotype in Macrophages
Authors: MC Montero, M Del Campo, M Bono, MV Simon, J Guerrero, N Lagos
Mar Drugs, 2020;18(6):.
-
TNF-&alpha Pretreatment Improves the Survival and Function of Transplanted Human Neural Progenitor Cells Following Hypoxic-Ischemic Brain Injury
Authors: M Kim, K Jung, Y Ko, IS Kim, K Hwang, JH Jang, JE Shin, KI Park
Cells, 2020;9(5):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis
Authors: E Zechendorf, CE O'Riordan, L Stiehler, N Wischmeyer, F Chiazza, D Collotta, B Denecke, S Ernst, G Müller-New, SM Coldewey, B Wissuwa, M Collino, TP Simon, T Schuerholz, C Stoppe, G Marx, C Thiemerman, L Martin
JCI Insight, 2020;5(8):.
Species: Mouse
Sample Types: Serum
-
M1 Polarization but Anti-LPS-Induced Inflammation and Anti-MCF-7 Breast Cancer Cell Growth Effects of Five Selected Polysaccharides
Authors: HC Lin, JY Lin
Evid Based Complement Alternat Med, 2020;2020(0):9450246.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis
Authors: H Liu, X Yang, K Tang, T Ye, C Duan, P Lv, L Yan, X Wu, Z Chen, J Liu, Y Deng, G Zeng, J Xing, Z Ye, H Xu
Theranostics, 2020;10(16):7319-7334.
Species: Mouse
Sample Types: Cell Culture Supernates
-
RANKL-independent osteoclastogenesis in the SH3BP2 cherubism mice
Authors: M Kittaka, T Yoshimoto, H Hoffman, ME Levitan, Y Ueki
Bone Rep, 2020;12(0):100258.
Species: Mouse
Sample Types: Serum
-
The Role of ST2 Receptor in the Regulation of Brucella abortus Oral Infection
Authors: R Santos, PC Campos, M Rungue, V Rocha, D Santos, V Mendes, FV Marinho, F Martins, MF Ricci, DCD Reis, GD Cassali, JC Alves-Filh, AT Vieira, SC Oliveira
Pathogens, 2020;9(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Calcitriol Prevents Neuroinflammation and Reduces Blood-Brain Barrier Disruption and Local Macrophage/Microglia Activation
Authors: LRC de Oliveir, LAN Mimura, TFC Fraga-Silv, LLW Ishikawa, AAH Fernandes, SFG Zorzella-P, A Sartori
Front Pharmacol, 2020;11(0):161.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model
Authors: AP Bonfanti, N Barreto, J Munhoz, M Caballero, G Cordeiro, T Rocha-E-Si, R Sutti, F Moura, S Brunetto, CD Ramos, R Thomé, L Verinaud, C Rapôso
Sci Rep, 2020;10(1):5876.
Species: Mouse
Sample Types: Cell Cultue Supernates
-
Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response
Authors: KA Sun, Y Li, AY Meliton, PS Woods, LM Kimmig, R Cetin-Atal, RB Hamanaka, GM Mutlu
Elife, 2020;9(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Fish oil reverses metabolic syndrome, adipocyte dysfunction, and altered adipokines secretion triggered by high-fat diet-induced obesity
Authors: RDC da Cunha d, MM Cruz, TM de Farias, VS da Silva, J de Jesus S, MM Telles, MIC Alonso-Val
Physiol Rep, 2020;8(4):e14380.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Disrupting Bordetella Immunosuppression Reveals a Role for Eosinophils in Coordinating the Adaptive Immune Response in the Respiratory Tract
Authors: MC Gestal, U Blas-Macha, HM Johnson, LN Rubin, KK Dewan, C Bryant, M Tiemeyer, ET Harvill
Microorganisms, 2020;8(11):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Tofacitinib treatment aggravates Staphylococcus aureus septic arthritis, but attenuates sepsis and enterotoxin induced shock in mice
Authors: A Jarneborn, M Mohammad, C Engdahl, Z Hu, M Na, A Ali, T Jin
Sci Rep, 2020;10(1):10891.
Species: Mouse
Sample Types: Serum
-
TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis
Authors: P Mandal, AL McCormick, ES Mocarski
Viruses, 2020;12(11):.
Species: Mouse
Sample Types: Tissue Homogenates
-
(E)-2-Cyano-3-(1H-Indol-3-yl)-N-Phenylacrylamide, a Hybrid Compound Derived from Indomethacin and Paracetamol: Design, Synthesis and Evaluation of the Anti-Inflammatory Potential
Authors: P Silva, M de Almeida, J Silva, S Albino, R Espírito-S, M Lima, C Villarreal, R Moura, V Santos
Int J Mol Sci, 2020;21(7):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Simvastatin Posttreatment Controls Inflammation and Improves Bacterial Clearance in Experimental Sepsis
Authors: FM de Jesus O, CF Gonçalves-, IMM de Moraes, PA Reis, VN Rocha, PT Bozza, AR Silva, HC de Castro
Mediators Inflamm, 2020;2020(0):1839762.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Skeletal muscle antagonizes antiviral CD8+ T cell exhaustion
Authors: J Wu, N Weisshaar, A Hotz-Wagen, A Madi, S Ma, A Mieg, M Hering, K Mohr, T Schlimbach, H Borgers, G Cui
Sci Adv, 2020;6(24):eaba3458.
Species: Mouse
Sample Types: Serum
-
Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners
Authors: X Li, M Zhang, X Huang, W Liang, G Li, X Lu, Y Li, H Pan, L Shi, H Zhu, L Qian, B Shan, J Yuan
Nature Communications, 2020;11(1):6364.
Species: Mouse
Sample Types: Serum
-
IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M
Authors: F Botelho, A Dubey, EA Ayaub, R Park, A Yip, A Humbles, R Kolbeck, CD Richards
Mediators of Inflammation, 2020;2020(0):4087315.
Species: Mouse
Sample Types: BALF
-
Active food ingredients production from cold pressed processing residues of Camellia oleifera and Camellia sinensis seeds for regulation of blood pressure and vascular function
Authors: SS Chiang, LS Chen, CY Chu
Chemosphere, 2020;267(0):129267.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Unique maternal immune and functional microbial profiles during prenatal stress
Authors: AM Antonson, MV Evans, JD Galley, HJ Chen, TA Rajasekera, SM Lammers, VL Hale, MT Bailey, TL Gur
Sci Rep, 2020;10(1):20288.
Species: Mouse
Sample Types: Tissue Homogenates
-
Waterpipe Tobacco Smoke Inhalation Triggers Thrombogenicity, Cardiac Inflammation and Oxidative Stress in Mice: Effects of Flavouring
Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, NE Zaaba, J Yasin, BH Ali
Int J Mol Sci, 2020;21(4):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Comparative Study on Pulmonary Toxicity in Mice Induced by Exposure to Unflavoured and Apple- and Strawberry-Flavoured Tobacco Waterpipe Smoke
Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, BH Ali
Oxid Med Cell Longev, 2020;2020(0):6450450.
Species: Mouse
Sample Types: Tissue Homogenates
-
High-Throughput CRISPR Screening Identifies Genes Involved in Macrophage Viability and Inflammatory Pathways
Authors: S Covarrubia, AC Vollmers, A Capili, M Boettcher, A Shulkin, MR Correa, H Halasz, EK Robinson, L O'Briain, C Vollmers, J Blau, S Katzman, MT McManus, S Carpenter
Cell Reports, 2020;33(13):108541.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Staphylococcus aureus-Derived &alpha-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution
Authors: PM Jordan, J Gerstmeier, S Pace, R Bilancia, Z Rao, F Börner, L Miek, Ó Gutiérrez-, V Arakandy, A Rossi, A Ialenti, C González-E, B Löffler, L Tuchscherr, CN Serhan, O Werz
Cell Rep, 2020;33(2):108247.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Electrostimulation of the carotid sinus nerve in mice attenuates inflammation via glucocorticoid receptor on myeloid immune cells
Authors: A Falvey, F Duprat, T Simon, S Hugues-Asc, SV Conde, N Glaichenha, P Blancou
Journal of Neuroinflammation, 2020;17(1):368.
Species: Mouse
Sample Types: Serum
-
HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation
Authors: XAMH van Dieren, MA de la Rosa, A Georgiadi, F Mattijssen, W Dijk, M van Weeghe, R Singh, JW Borst, R Stienstra, S Kersten
Cell Rep, 2020;30(6):1811-1822.e6.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes
Authors: T Sakaguchi, R Okumura, C Ono, D Okuzaki, T Kawai, Y Okochi, N Tanimura, M Murakami, H Kayama, E Umemoto, H Kioka, T Ohtani, Y Sakata, K Miyake, Y Okamura, Y Baba, K Takeda
Cell Rep, 2020;31(10):107755.
Species: Mouse
Sample Types: Serum
-
Intracellular ROS Scavenging and Anti-Inflammatory Activities of Oroxylum indicum Kurz (L.) Extract in LPS plus IFN-gamma-Activated RAW264.7 Macrophages
Authors: B Dunkhuntho, C Talabnin, M Murphy, K Thumanu, P Sittisart, T Hengpratom, G Eumkeb
Evid Based Complement Alternat Med, 2020;2020(0):7436920.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Severity of Experimental Autoimmune Uveitis Is Reduced by Pretreatment with Live Probiotic Escherichia coli Nissle 1917
Authors: O Dusek, A Fajstova, A Klimova, P Svozilkova, T Hrncir, M Kverka, S Coufal, J Slemin, H Tlaskalova, JV Forrester, J Heissigero
Cells, 2020;10(1):.
Species: Mouse
Sample Types: Tissue Culture Supernates
-
Inducing regulated necrosis and shifting macrophage polarization with anti-EMMPRIN antibody (161-pAb) and complement factors
Authors: N Hijaze, M Ledersnaid, E Simanovich, S Kassem, MA Rahat
J Leukoc Biol, 2020;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Acorus gramineusand and Euodia ruticarpa Steam Distilled Essential Oils Exert Anti-Inflammatory Effects Through Decreasing Th1/Th2 and Pro-/Anti-Inflammatory Cytokine Secretion Ratios In Vitro
Authors: TH Yeh, JY Lin
Biomolecules, 2020;10(2):.
Species: Mouse
Sample Types: Cell Lysates
-
Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation
Authors: H Ma, J Wang, X Zhao, T Wu, Z Huang, D Chen, Y Liu, G Ouyang
Cell Rep, 2020;30(3):793-806.e6.
Species: Mouse
Sample Types: Tissue Homogenates
-
Immunomodulatory Effect of a Salvia plebeia R. Aqueous Extract in Forced Swimming Exercise-induced Mice
Authors: J Shin, OK Kim, S Kim, D Bae, J Lee, J Park, W Jun
Nutrients, 2020;12(8):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lactococcus lactis subsp. Cremoris C60 restores T Cell Population in Small Intestinal Lamina Propria in Aged Interleukin-18 Deficient Mice
Authors: S Saito, N Kakizaki, A Okuno, T Maekawa, NM Tsuji
Nutrients, 2020;12(11):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The protective role of proton-sensing TDAG8 in the brain injury in a mouse ischemia reperfusion model
Authors: K Sato, A Tobo, C Mogi, M Tobo, N Yamane, M Tosaka, H Tomura, DS Im, F Okajima
Sci Rep, 2020;10(1):17193.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice
Authors: J Wang, C Ortiz, L Fontenot, R Mukhopadhy, Y Xie, IKM Law, DQ Shih, SA Mattai, Z Li, HW Koon
Sci Rep, 2020;10(1):12785.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling
Authors: A Fajstova, N Galanova, S Coufal, J Malkova, M Kostovcik, M Cermakova, H Pelantova, M Kuzma, B Sediva, T Hudcovic, T Hrncir, H Tlaskalova, M Kverka, K Kostovciko
Cells, 2020;9(12):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TXNIP Regulates Natural Killer Cell-Mediated Innate Immunity by Inhibiting IFN-&gamma Production during Bacterial Infection
Authors: DO Kim, JE Byun, WS Kim, MJ Kim, JH Choi, H Kim, E Choi, TD Kim, SR Yoon, JY Noh, YJ Park, J Lee, HJ Cho, HG Lee, SH Min, I Choi, H Jung
International Journal of Molecular Sciences, 2020;21(24):.
Species: Mouse
Sample Types: Serum
-
Neuroinflammaging underlies emotional disturbances and circadian rhythm disruption in young male senescence-accelerated mouse prone 8 mice
Authors: N Ito, H Takemoto, A Hasegawa, C Sugiyama, K Honma, T Nagai, Y Kobayashi, H Odaguchi
Exp Gerontol, 2020;0(0):111109.
Species: Mouse
Sample Types: Serum
-
Low Molecular Weight and Polymeric Modifiers as Toughening Agents in Poly(3-Hydroxybutyrate) Films
Authors: AN Frone, CA Nicolae, MC Eremia, V Tofan, M Ghiurea, I Chiulan, E Radu, CM Damian, DM Panaitescu
Polymers (Basel), 2020;12(11):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease
Authors: DM de Graaf, RJA Maas, SP Smeekens, E Eisenmesse, JS Redzic, MM Helsen, NE Powers, S Li, V Kalabokis, MS Gresnigt, LAB Joosten, CA Dinarello, FL van de Vee
Cytokine, 2020;137(0):155334.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Pseudomonas aeruginosa protease LasB directly activates IL-1&beta
Authors: J Sun, DL LaRock, EA Skowronski, JM Kimmey, J Olson, Z Jiang, AJ O'Donoghue, V Nizet, CN LaRock
EBioMedicine, 2020;60(0):102984.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation
Authors: P Deo, SH Chow, ML Han, M Speir, C Huang, RB Schittenhe, S Dhital, J Emery, J Li, BT Kile, JE Vince, KE Lawlor, T Naderer
Nat Microbiol, 2020;0(0):.
Species: Mouse
Sample Types: Serum
-
Phoenixin 14 Inhibits High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Experimental Mice
Authors: F Yang, P Huang, L Shi, F Liu, A Tang, S Xu
Drug Des Devel Ther, 2020;14(0):3865-3874.
Species: Mouse
Sample Types: Tissue Homogenates
-
RACK1 Mediates NLRP3 Inflammasome Activation by Promoting NLRP3 Active Conformation and Inflammasome Assembly
Authors: Y Duan, L Zhang, D Angosto-Ba, P Pelegrín, G Núñez, Y He
Cell Rep, 2020;33(7):108405.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Maternal Obesity Does Not Exacerbate the Effects of LPS Injection on Pregnancy Outcomes in Mice
Authors: N Virginkar, JK Christians
Biology, 2020;9(9):.
Species: Mouse
Sample Types: Serum
-
Peptidorhamnomannan from Lomentospora prolificans modulates the inflammatory response in macrophages infected with Candida albicans
Authors: MIDDS Xisto, SS Santos, L Rossato, FSY Yoshikawa, RMT Haido, SR de Almeida, E Barreto-Be
BMC Microbiol., 2020;20(1):245.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Humanized COVID-19 decoy antibody effectively blocks viral entry and prevents SARS-CoV-2 infection
Authors: KY Huang, MS Lin, TC Kuo, CL Chen, CC Lin, YC Chou, TL Chao, YH Pang, HC Kao, RS Huang, S Lin, SY Chang, PC Yang
EMBO Mol Med, 2020;0(0):e12828.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus
Authors: L Whitesell, N Robbins, DS Huang, CA McLellan, T Shekhar-Gu, EV LeBlanc, CS Nation, R Hui, A Hutchinson, C Collins, S Chatterjee, R Trilles, JL Xie, DJ Krysan, S Lindquist, JA Porco, U Tatu, LE Brown, J Pizarro, LE Cowen
Nat Commun, 2019;10(1):402.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin
Authors: AML Scantleber, M Uil, LM Butter, R Poelman, N Claessen, SE Girardin, S Florquin, JJTH Roelofs, JC Leemans
PLoS ONE, 2019;14(3):e0214437.
Species: Mouse
Sample Types: Tissue Homogenates
-
A Live Salmonella Vaccine Delivering PcrV through the Type III Secretion System Protects against Pseudomonas aeruginosa
Authors: J Aguilera-H, M García-Qui, R Romero-Flo, MJ McConnell, F Ramos-Mora
mSphere, 2019;4(2):.
Species: Mouse
Sample Types: Serum
-
Immunomodulatory effects of cyanobacterial toxin cylindrospermopsin on innate immune cells
Authors: Z Moosova, M Pekarova, LS Sindlerova, O Vasicek, L Kubala, L Blaha, O Adamovsky
Chemosphere, 2019;226(0):439-446.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Elevated circulating TGF?1 during acute liver failure activates TGF?R2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice
Authors: M McMillin, S Grant, G Frampton, AD Petrescu, E Williams, B Jefferson, A Thomas, A Brahmarout, S DeMorrow
J Neuroinflammation, 2019;16(1):69.
Species: Mouse
Sample Types: Tissue Homogenates
-
Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism
Authors: JL Fachi, JS Felipe, LP Pral, BK da Silva, RO Corrêa, MCP de Andrade, DM da Fonseca, PJ Basso, NOS Câmara, ÉL de Sales E, F Dos Santos, SES Guima, AM Thomas, JC Setubal, YT Magalhães, FL Forti, T Candreva, HG Rodrigues, MB de Jesus, SR Consonni, ADS Farias, P Varga-Weis, MAR Vinolo
Cell Rep, 2019;27(3):750-761.e7.
Species: Mouse
Sample Types: Tissue Homogenates
-
Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist
Authors: S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett
Stem Cells, 2019;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice
Authors: VB Lê, J Dubois, C Couture, MH Cavanagh, O Uyar, A Pizzorno, M Rosa-Calat, MÈ Hamelin, G Boivin
PLoS Pathog., 2019;15(4):e1007689.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice
Authors: Z Gong, J Huang, B Xu, Z Ou, L Zhang, X Lin, X Ye, X Kong, D Long, X Sun, X He, L Xu, Q Li, A Xuan
J Neuroinflammation, 2019;16(1):62.
Species: Mouse
Sample Types: Tissue Homogenates
-
Obesity Expands a Distinct Population of T Cells in Adipose Tissue and Increases Vulnerability to Infection
Authors: I Misumi, J Starmer, T Uchimura, MA Beck, T Magnuson, JK Whitmire
Cell Rep, 2019;27(2):514-524.e5.
Species: Mouse
Sample Types: Whole Blood
-
In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy
Authors: VN Camargos, G Foureaux, DC Medeiros, VT da Silveir, CM Queiroz-Ju, ALB Matosinhos, AFA Figueiredo, CDF Sousa, TP Moreira, VF Queiroz, ACF Dias, KTO Santana, I Passos, ALCV Real, LC Silva, FAG Mourão, NT Wnuk, MAP Oliveira, S Macari, T Silva, GP Garlet, JA Jackman, FM Soriani, MFD Moraes, EMAM Mendes, FM Ribeiro, GMJ Costa, AL Teixeira, NJ Cho, ACP Oliveira, MM Teixeira, VV Costa, DG Souza
EBioMedicine, 2019;0(0):.
Species: Mouse
Sample Types: Plasma
-
Context-specific switch from anti- to pro-epileptogenic function of the P2Y1 receptor in experimental epilepsy
Authors: M Alves, L De Diego G, G Conte, EM Jimenez-Ma, B D'Orsi, A Sanz-Rodri, JH Prehn, DC Henshall, T Engel
J. Neurosci., 2019;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Glycolysis Is an Intrinsic Factor for Optimal Replication of a Norovirus
Authors: KD Passalacqu, J Lu, I Goodfellow, AO Kolawole, JR Arche, RJ Maddox, KE Carnahan, MXD O'Riordan, CE Wobus
MBio, 2019;10(2):.
Species: Mouse
Sample Types: Cell Lysates
-
Cathelicidins PMAP-36, LL-37 and CATH-2 are similar peptides with different modes of action
Authors: MR Scheenstra, M van den Be, JLM Tjeerdsma-, VAF Schneider, SR Ordonez, A van Dijk, EJA Veldhuizen, HP Haagsman
Sci Rep, 2019;9(1):4780.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1?-dependent manner in macrophages
Authors: OM Finucane, J Sugrue, A Rubio-Arai, MV Guillot-Se, MA Lynch
Sci Rep, 2019;9(1):4034.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury
Authors: G Thomi, D Surbek, V Haesler, M Joerger-Me, A Schoeberle
Stem Cell Res Ther, 2019;10(1):105.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gum Arabic Ameliorates Impaired Coagulation and Cardiotoxicity Induced by Water-Pipe Smoke Exposure in Mice
Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, BH Ali
Front Physiol, 2019;10(0):53.
Species: Mouse
Sample Types: Tissue Homogenates
-
Long noncoding RNA Malat1 regulates differential activation of macrophage and response to lung injury
Authors: H Cui, S Banerjee, S Guo, N Xie, J Ge, D Jiang, M Zörnig, VJ Thannickal, G Liu
JCI Insight, 2019;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Exercise-induced AMPK activation and IL-6 muscle production are disturbed in adiponectin knockout mice
Authors: TA Diniz, JCJ Aquino Jún, FC Mosele, C Cabral-San, EA Lima Junio, AAS Teixeira, FS Lira, JC Rosa Neto
Cytokine, 2019;119(0):71-80.
Species: Mouse
Sample Types: Tissue Homogenates
-
Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice
Authors: AC Luissint, HC Williams, W Kim, S Flemming, V Azcutia, RS Hilgarth, MNO Leary, TL Denning, A Nusrat, CA Parkos
Mucosal Immunol, 2019;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Murine astrocytes produce IL-24 and are susceptible to the immunosuppressive effects of this cytokine
Authors: AR Burmeister, MB Johnson, JJ Yaemmongko, I Marriott
J Neuroinflammation, 2019;16(1):55.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intravascular heavy chain-modification of hyaluronan during endotoxic shock
Authors: K Ni, A Gill, D Cao, K Koike, KS Schweitzer, S Garantziot, I Petrache
Biochem Biophys Rep, 2019;17(0):114-121.
Species: Mouse
Sample Types: Plasma
-
Rapid synthesis and immunogenicity of mycobacterial (1?5)-?-d-arabinofuranan
Authors: H Leelayuwap, S Ruchirawat, S Boonyaratt
Carbohydr Polym, 2019;206(0):262-272.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Modifying internal organization and surface morphology of siRNA lipoplexes by sodium alginate addition for efficient siRNA delivery
Authors: DC Arruda, IJ Gonzalez, S Finet, L Cordova, V Trichet, GF Andrade, C Hoffmann, P Bigey, WA de Almeida, A Da Silva C, A Malachias, V Escriou
J Colloid Interface Sci, 2019;540(0):342-353.
Species: Mouse
Sample Types: Serum
-
In�Vitro Macrophage Assay Predicts the In�Vivo Anti-inflammatory Potential of Exosomes from Human Mesenchymal Stromal Cells
Authors: N Pacienza, RH Lee, EH Bae, DK Kim, Q Liu, DJ Prockop, G Yannarelli
Mol Ther Methods Clin Dev, 2019;13(0):67-76.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Water Extract of Acori Graminei Rhizoma Attenuates Features of Rheumatoid Arthritis in DBA/1 Mice
Authors: JH Nho, AH Kim, HK Jung, MJ Lee, JH Jang, BD Yang, HJ Lee, KH Lee, KW Woo, HW Cho
Evid Based Complement Alternat Med, 2019;2019(0):3637453.
Species: Mouse
Sample Types: Serum
-
EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke
Authors: AS Ernst, LI Böhler, AM Hagenston, A Hoffmann, S Heiland, C Sticht, M Bendszus, M Hecker, H Bading, HH Marti, T Korff, R Kunze
Acta Neuropathol Commun, 2019;7(1):15.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Effect of Saururus chinensis leaves extract on type II collagen-induced arthritis mouse model
Authors: JH Nho, HJ Lee, HK Jung, JH Jang, KH Lee, AH Kim, TK Sung, HW Cho
BMC Complement Altern Med, 2019;19(1):2.
Species: Mouse
Sample Types: Serum
-
Neurological Enhancement Effects of Melatonin against Brain Injury-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration via AMPK/CREB Signaling
Authors: SU Rehman, M Ikram, N Ullah, SI Alam, HY Park, H Badshah, K Choe, MO Kim
Cells, 2019;8(7):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression
Authors: S De, DR Whiten, FS Ruggeri, C Hughes, M Rodrigues, DI Sideris, CG Taylor, FA Aprile, S Muylderman, TPJ Knowles, M Vendruscol, C Bryant, K Blennow, I Skoog, S Kern, H Zetterberg, D Klenerman
Acta Neuropathol Commun, 2019;7(1):120.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Comprehensive characterization of silica-modified silicon rubbers
Authors: I Chiulan, DM Panaitescu, ER Radu, AN Frone, RA Gabor, CA Nicolae, G Jinescu, V Tofan, G Chinga-Car
J Mech Behav Biomed Mater, 2019;101(0):103427.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The dynamic uptake and release of SOD3 from intracellular stores in macrophages modulates the inflammatory response
Authors: L Hu, ED Zachariae, UG Larsen, F Vilhardt, SV Petersen
Redox Biol, 2019;26(0):101268.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Strongyloides venezuelensis-infection alters the profile of cytokines and liver inflammation in mice co-infected with Schistosoma mansoni
Authors: MC de Rezende, JMP Moreira, LLM Fernandes, VF Rodrigues, D Negrão-Cor
Cytokine, 2019;127(0):154931.
Species: Mouse
Sample Types: Tissue Homogenates
-
Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation
Authors: MM Hughes, A Hooftman, S Angiari, P Tummala, Z Zaslona, MC Runtsch, AF McGettrick, CE Sutton, C Diskin, M Rooke, S Takahashi, S Sundararaj, MG Casarotto, JE Dahlstrom, EM Palsson-Mc, SC Corr, KHG Mills, RJS Preston, N Neamati, Y Xie, JB Baell, PG Board, LAJ O'Neill
Cell Rep, 2019;29(1):151-161.e5.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy
Authors: M Torvell, DW Hampton, P Connick, AMJ MacLullich, C Cunningham, S Chandran
Alzheimers Dement (N Y), 2019;5(0):579-591.
Species: Mouse
Sample Types: Serum
-
Exposure to lipopolysaccharide (LPS) reduces contractile response of small airways from GSTCD-/- mice
Authors: B Liu, AP Henry, S Azimi, S Miller, FK Lee, JC Lee, K Probert, MI Kotlikoff, I Sayers, IP Hall
PLoS ONE, 2019;14(9):e0221899.
Species: Mouse
Sample Types: Tissue Culture Supernates
-
Maternal Obesity in Mice Exacerbates the Allergic Inflammatory Response in the Airways of Male Offspring
Authors: RR E-Lacerda, CJ Teixeira, S Bordin, E Antunes, GF Anhê
Nutrients, 2019;11(12):.
Species: Mouse
Sample Types: BALF
-
SOCS2 modulates adipose tissue inflammation and expansion in mice
Authors: CH Val, MC de Oliveir, DR Lacerda, A Barroso, NV Batista, Z Menezes-Ga, DRR de Assis, AT Cramer, F Brant, MM Teixeira, D Glória Sou, AM Ferreira, FS Machado
J. Nutr. Biochem., 2019;76(0):108304.
Species: Mouse
Sample Types: Tissue Homogenates
-
Mucoadhesive dexamethasone-glycol chitosan nanoparticles for ophthalmic drug delivery
Authors: A Yu, H Shi, H Liu, Z Bao, M Dai, D Lin, D Lin, X Xu, X Li, Y Wang
Int J Pharm, 2019;575(0):118943.
Species: Mouse
Sample Types: Cell Culture Supernates
-
DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells
Authors: A Suhail, ZA Rizvi, P Mujagond, SA Ali, P Gaur, M Singh, V Ahuja, A Awasthi, CV Srikanth
Cell Rep, 2019;29(11):3522-3538.e7.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A novel mouse model for septic arthritis induced by Pseudomonas aeruginosa
Authors: T Jin, M Mohammad, Z Hu, Y Fei, ERB Moore, R Pullerits, A Ali
Sci Rep, 2019;9(1):16868.
Species: Mouse
Sample Types: Serum
-
miR-124 ameliorates depressive-like behavior by targeting STAT3 to regulate microglial activation
Authors: D Lou, J Wang, X Wang
Mol. Cell. Probes, 2019;0(0):101470.
Species: Mouse
Sample Types: Tissue Homogenates
-
The effects of oxygen concentration on cell death, anti-oxidant transcription, acute inflammation, and cell proliferation in precision-cut lung slices
Authors: MJR Ruigrok, J Tomar, HW Frijlink, BN Melgert, WLJ Hinrichs, P Olinga
Sci Rep, 2019;9(1):16239.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2
Authors: PS Sung, TF Huang, SL Hsieh
Nat Commun, 2019;10(1):2402.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The YIN and YANG of lipoproteins in developing and preventing infectious arthritis by Staphylococcus aureus
Authors: M Mohammad, MT Nguyen, C Engdahl, M Na, A Jarneborn, Z Hu, A Karlsson, R Pullerits, A Ali, F Götz, T Jin
PLoS Pathog., 2019;15(6):e1007877.
Species: Mouse
Sample Types: Tissue Homogenates
-
Regulation of macrophage activity by surface receptors contained within Borrelia burgdorferi-enriched phagosomal fractions
Authors: A Carreras-G, D Barriales, A Palacios, M Montesinos, N Navasa, M Azkargorta, A Peña-Cearr, J Tomás-Cort, I Escobes, MA Pascual-It, J Hradiská, J Kopecký, D Gil-Carton, R Prados-Ros, L Abecia, E Atondo, I Martín, A Pellón, F Elortza, H Rodríguez, J Anguita
PLoS Pathog., 2019;15(11):e1008163.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Frontline Science: Acyl-CoA synthetase 1 exacerbates lipotoxic inflammasome activation in primary macrophages
Authors: G Kalugotla, L He, KJ Weber, S Daemen, A Reller, B Razani, JD Schilling
J. Leukoc. Biol., 2019;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Oral administration of EPA-rich oil impairs collagen reorganization due to elevated production of IL-10 during skin wound healing in mice
Authors: B Burger, CMC Kühl, T Candreva, RDS Cardoso, JR Silva, BG Castelucci, SR Consonni, HL Fisk, PC Calder, MAR Vinolo, HG Rodrigues
Sci Rep, 2019;9(1):9119.
Species: Mouse
Sample Types: Tissue Homogenates
-
Waterpipe Smoke Exposure Triggers Lung Injury and Functional Decline in Mice: Protective Effect of Gum Arabic
Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, BH Ali
Oxid Med Cell Longev, 2019;2019(0):8526083.
Species: Mouse
Sample Types: Tissue Homogenates
-
Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation
Authors: JD Bailey, M Diotallevi, T Nicol, E McNeill, A Shaw, S Chuaiphich, A Hale, A Starr, M Nandi, E Stylianou, H McShane, S Davis, R Fischer, BM Kessler, J McCullagh, KM Channon, MJ Crabtree
Cell Rep, 2019;28(1):218-230.e7.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Enzyme Treatment Alters the Anti-Inflammatory Activity of the Water Extract of Wheat Germ In Vitro and In Vivo
Authors: Y Song, HY Jeong, JK Lee, YS Choi, DO Kim, D Jang, CS Park, S Maeng, H Kang
Nutrients, 2019;11(10):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunomodulatory effect of Syphacia obvelata in treatment of experimental DSS-induced colitis in mouse model
Authors: N Taghipour, N Mosaffa, HA Aghdaei, M Rostami-Ne, JV Weinstock, S Shahnavaz, MR Zali
Sci Rep, 2019;9(1):19127.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of adipose tissue inflammation in fat pad loss induced by fasting in lean and mildly obese mice
Authors: DR Lacerda, KA Costa, ALM Silveira, DF Rodrigues, AN Silva, JL Sabino, V Pinho, GB Menezes, DD Soares, MM Teixeira, AVM Ferreira
J. Nutr. Biochem., 2019;72(0):108208.
Species: Mouse
Sample Types: Tissue Homogenates
-
PTP1B negatively regulates nitric oxide-mediated Pseudomonas aeruginosa killing by neutrophils
Authors: L Yue, M Yan, ML Tremblay, TJ Lin, H Li, T Yang, X Song, T Xie, Z Xie
PLoS ONE, 2019;14(9):e0222753.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis
Authors: Y Lin, B Li, X Yang, T Liu, T Shi, B Deng, Y Zhang, L Jia, Z Jiang, R He
Mucosal Immunol, 2019;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae
Authors: J Periselner, G Ercoli, T Pollard, S Chimalapat, E Camberlein, G Szylar, C Hyams, G Tomlinson, FC Petersen, RA Floto, M Noursadegh, JS Brown
MBio, 2019;10(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Syk-dependent glycolytic reprogramming in dendritic cells regulates IL-1 β production to β-glucan ligands in a TLR-independent manner
Authors: PM Thwe, DI Fritz, JP Snyder, PR Smith, KD Curtis, A O'Donnell, NA Galasso, LA Sepaniac, BJ Adamik, LR Hoyt, PD Rodriguez, TC Hogan, AF Schmidt, ME Poynter, E Amiel
J. Leukoc. Biol., 2019;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism
Authors: GI Lancaster, KG Langley, NA Berglund, HL Kammoun, S Reibe, E Estevez, J Weir, NA Mellett, G Pernes, JRW Conway, MKS Lee, P Timpson, AJ Murphy, SL Masters, S Gerondakis, N Bartonicek, DC Kaczorowsk, ME Dinger, PJ Meikle, PJ Bond, MA Febbraio
Cell Metab., 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Protective Effects of Anti-IL17 on Acute Lung Injury Induced by LPS in Mice
Authors: RF Righetti, TM Dos Santos, LDN Camargo, LRCRB Aristótele, S Fukuzaki, FCR de Souza, FPR Santana, MVR de Agrela, MM Cruz, MIC Alonso-Val, IS Genaro, BM Saraiva-Ro, EA Leick, MA Martins, CM Prado, IFLC Tibério
Front Pharmacol, 2018;9(0):1021.
Species: Mouse
Sample Types: Tissue Homogenates
-
Genetic Polymorphism at CCL5 Is Associated With Protection in Chagas' Heart Disease: Antagonistic Participation of CCR1+ and CCR5+ Cells in Chronic Chagasic Cardiomyopathy.
Authors: Angelica Martins Batista, Lucia Elena Alvarado-, Silvia Marinho Alves, Gloria Melo, Isabela Resende Pereira, Leonardo Alexandre de Sou Ruivo, Andrea Alice Da Silva, Daniel Gibaldi, Thayse Do E S Protásio Da Silva, Virginia Maria Barros De Lorena, Adriene Siqueira De Melo, Ana Karine De Araújo, Michelle Da Silva Barros, Vláudia Maria Assis Costa, Cynthia C Cardoso, Antonio G Pacheco, Cristina Carrazzon, Wilson Oliveira, Milton Ozório Moraes, Joseli Lannes-Vi
Frontiers in Immunology, 2018;0(0):1664-3224.
Species: Mouse
Sample Types: Tissue Homogenates
-
Targeting SHIP-1 in Myeloid Cells Enhances Trained Immunity and Boosts Response to Infection
Authors: P Saz-Leal, C Del Fresno, P Brandi, S Martínez-C, OM Dungan, JD Chisholm, WG Kerr, D Sancho
Cell Rep, 2018;25(5):1118-1126.
Species: Mouse
Sample Types: Serum
-
Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice
Authors: CW Hui, X Song, F Ma, X Shen, K Herrup
J Neuroinflammation, 2018;15(1):308.
Species: Mouse
Sample Types: Tissue Homogenates
-
Nicotine promotes neuron survival and partially protects from Parkinson's disease by suppressing SIRT6
Authors: JW Nicholatos, AB Francisco, CA Bender, T Yeh, FJ Lugay, JE Salazar, C Glorioso, S Libert
Acta Neuropathol Commun, 2018;6(1):120.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection
Authors: V Ciancarell, L Lembo-Fazi, I Paciello, AK Bruno, S Jaillon, S Berardi, M Barbagallo, S Meron-Suda, D Cohen, A Molinaro, G Rossi, C Garlanda, ML Bernardini
PLoS Pathog., 2018;14(12):e1007469.
Species: Mouse
Sample Types: Tissue Homogenates
-
IGF-1-Overexpressing Mesenchymal Stem/Stromal Cells Promote Immunomodulatory and Proregenerative Effects in Chronic Experimental Chagas Disease
Authors: DN Silva, BSF Souza, CM Azevedo, JF Vasconcelo, PG de Jesus, MS Feitoza, CS Meira, GB Carvalho, BR Cavalcante, R Ribeiro-Do, MBP Soares
Stem Cells Int, 2018;2018(0):9108681.
Species: Mouse
Sample Types: Serum
-
Omega-9 Oleic Acid, the Main Compound of Olive Oil, Mitigates Inflammation during Experimental Sepsis
Authors: IM Medeiros-d, CF Gonçalves-, ARM Kurz, FMJ Oliveira, VHP de Abreu, RC Torres, VF Carvalho, V Estato, PT Bozza, M Sperandio, HC de Castro-, AR Silva
Oxid Med Cell Longev, 2018;2018(0):6053492.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Bovine milk-derived extracellular vesicles enhance inflammation and promote M1 polarization following agricultural dust exposure in mice
Authors: TM Nordgren, AJ Heires, J Zempleni, BJ Swanson, C Wichman, DJ Romberger
J. Nutr. Biochem., 2018;64(0):110-120.
Species: Mouse
Sample Types: BALF
-
EGF receptor plays a role in the mechanism of glutamine-mediated prevention of alcohol-induced gut barrier dysfunction and liver injury
Authors: AS Meena, PK Shukla, P Sheth, R Rao
J. Nutr. Biochem., 2018;64(0):128-143.
Species: Mouse
Sample Types: Plasma
-
Enzymatic Activity Is Not Required for Phospholipase D Mediated TNF-? Regulation and Myocardial Healing
Authors: M Klier, S Gorressen, MA Urbahn, D Barbosa, M Ouwens, JW Fischer, M Elvers
Front Physiol, 2018;9(0):1698.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The novel immunoglobulin super family receptor SLAMF9 identified in TAM of murine and human melanoma influences pro-inflammatory cytokine secretion and migration
Authors: C Dollt, J Michel, L Kloss, S Melchers, K Schledzews, K Becker, A Sauer, A Krewer, F Koll, A Schmieder
Cell Death Dis, 2018;9(10):939.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Electrophilic properties of itaconate and derivatives regulate the�I?B?-ATF3 inflammatory axis
Authors: M Bambouskov, L Gorvel, V Lampropoul, A Sergushich, E Loginichev, K Johnson, D Korenfeld, ME Mathyer, H Kim, LH Huang, D Duncan, H Bregman, A Keskin, A Santeford, RS Apte, R Sehgal, B Johnson, GK Amarasingh, MP Soares, T Satoh, S Akira, T Hai, C de Guzman, K Auclair, TP Roddy, SA Biller, M Jovanovic, E Klechevsky, KM Stewart, GJ Randolph, MN Artyomov
Nature, 2018;556(7702):501-504.
Species: Mouse
Sample Types: Cell Cultue Supernates
-
Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha
Authors: A Kia, K McAvoy, K Krishnamur, D Trotti, P Pasinelli
Glia, 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunomodulatory effects of polysaccharide fraction isolated from Fagopyrum esculentum on innate immune system
Authors: MJ Oh, HD Choi, SK Ha, I Choi, HY Park
Biochem. Biophys. Res. Commun., 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Genetically Engineered Resveratrol-Enriched Rice Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia Via Downregulating Mitogen-Activated Protein Kinase-Nuclear Factor Kappa B Signaling Pathway
Authors: L Subedi, SH Baek, SY Kim
Oxid Med Cell Longev, 2018;2018(0):8092713.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses
Authors: L Boutens, GJ Hooiveld, S Dhingra, RA Cramer, MG Netea, R Stienstra
Diabetologia, 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Second-generation SYK inhibitor entospletinib ameliorates fully established inflammation and bone destruction in the cherubism mouse model
Authors: T Yoshimoto, T Hayashi, T Kondo, M Kittaka, EJ Reichenber, Y Ueki
J. Bone Miner. Res., 2018;0(0):.
Species: Mouse
Sample Types: Serum
-
Magnolol protects against ischemic-reperfusion brain damage following oxygen-glucose deprivation and transient focal cerebral ischemia
Authors: SY Huang, SH Tai, CC Chang, YF Tu, CH Chang, EJ Lee
Int. J. Mol. Med., 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence
Authors: C Wang, KA Bauckman, ASB Ross, JW Symington, MM Ligon, G Scholtes, A Kumar, HW Chang, J Twentyman, BE Fashemi, RJ Xavier, IU Mysorekar
Autophagy, 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop
Authors: F Mouton-Lig, T Rosazza, J Sepulveda-, A Ieang, SM Hassoun, E Claire, G Mangone, A Brice, PP Michel, JC Corvol, O Corti
Glia, 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TLR4 (toll-like receptor 4) activation suppresses autophagy through inhibition of FOXO3 and impairs phagocytic capacity of microglia
Authors: JW Lee, H Nam, LE Kim, Y Jeon, H Min, S Ha, Y Lee, SY Kim, SJ Lee, EK Kim, SW Yu
Autophagy, 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Candesartan ameliorates brain inflammation associated with Alzheimer's disease
Authors: N Torika, K Asraf, RN Apte, S Fleisher-B
CNS Neurosci Ther, 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
In Vivo Protective Effects of Nootkatone against Particles-Induced Lung Injury Caused by Diesel Exhaust Is Mediated via the NF-?B Pathway
Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, N Hamadi, BH Ali
Nutrients, 2018;10(3):.
Species: Mouse
Sample Types: Tissue Homogenates
-
EBI2 regulates pro-inflammatory signalling and cytokine release in astrocytes
Authors: A Rutkowska, DR Shimshek, AW Sailer, KK Dev
Neuropharmacology, 2018;133(0):121-128.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Murine neutrophils treated with alphaB-crystallin reduce IL-12p40 production by dendritic cells
Authors: TM Finlay, AL Palmer, SS Ousman
Immunology, 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A multi-omic analysis reveals the regulatory role of CD180 during the response of macrophages to Borrelia burgdorferi
Authors: A Carreras-G, N Navasa, I Martín-Rui, JL Lavín, M Azkargorta, E Atondo, D Barriales, N Macías-Cám, MA Pascual-It, L Sampedro, J Tomás-Cort, A Peña-Cearr, A Pellón, R Prados-Ros, L Abecia, F Elortza, AM Aransay, H Rodríguez, J Anguita
Emerg Microbes Infect, 2018;7(1):19.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair
Authors: D Gr?evi?, M Sironi, S Valentino, L Deban, H Cvija, A Inforzato, N Kova?i?, V Katavi?, T Kelava, I Kalajzi?, A Mantovani, B Bottazzi
Front Immunol, 2018;9(0):417.
Species: Mouse
Sample Types: Serum
-
Probiotic treatment during neonatal age provides optimal protection against experimental asthma through the modulation of microbiota and T cells: Neonatal exposure to probiotics prevents asthma
Authors: CFCG Nunes, JS Nogueira, FB Canto, PHO Vianna, BT Ciambarell, PMRE Silva, KR Miranda, LA Lobo, RMCP Domingues, M Busch, GC Atella, AM Vale, M Bellio, A Nóbrega, R Fucs
Int. Immunol., 2018;0(0):.
Species: Mouse
Sample Types: BALF
Applications: ELISA Capture -
SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages
Authors: M Yurchenko, A Skjesol, L Ryan, GM Richard, RK Kandasamy, N Wang, C Terhorst, H Husebye, T Espevik
J. Cell Biol., 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture S
-
Activation of hypoxia-inducible factor�1 attenuates periapical inflammation and bone loss
Authors: K Hirai, H Furusho, K Hirota, H Sasaki
Int J Oral Sci, 2018;10(2):12.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism
Authors: N Eissa, P Jayaprakas, S Azimullah, SK Ojha, M Al-Houqani, FY Jalal, D ?a?ewska, K Kie?-Konon, B Sadek
Sci Rep, 2018;8(1):13077.
Species: Mouse
Sample Types: Tissue Homogenates
-
Analysis of the Trichuris suis excretory/secretory proteins as a function of life cycle stage and their immunomodulatory properties
Authors: LP Leroux, M Nasr, R Valanparam, M Tam, BA Rosa, E Siciliani, DE Hill, DS Zarlenga, M Jaramillo, JV Weinstock, TG Geary, MM Stevenson, JF Urban, M Mitreva, A Jardim
Sci Rep, 2018;8(1):15921.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis
Authors: F Fattahi, MW Russell, EA Malan, M Parlett, E Abe, FS Zetoune, PA Ward
Biomed Res Int, 2018;2018(0):4302726.
Species: Mouse
Sample Types: Plasma
-
Activation of M1 macrophages play a critical role in the initiation of acute lung injury
Authors: HL Lu, XY Huang, YF Luo, WP Tan, PF Chen, YB Guo
Biosci. Rep., 2018;0(0):.
Species: Mouse
Sample Types: Serum
-
Induction of endoplasmic reticulum stress under endotoxin tolerance increases inflammatory responses and decreases Pseudomonas aeruginosa pneumonia
Authors: S Kim, Y Joe, SU Park, SO Jeong, JK Kim, SH Park, HO Pae, YJ Surh, J Shin, HT Chung
J. Leukoc. Biol., 2018;0(0):.
Species: Mouse
Sample Types: BALF
-
Canonical PI3K? signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis
Authors: MC Silva, M Davoli-Fer, TS Medina, R Sesti-Cost, GK Silva, CD Lopes, LE Cardozo, FN Gava, K Lyroni, FC Dias, AF Frade, M Baron, HI Nakaya, F Figueiredo, JC Alves-Filh, FQ Cunha, C Tsatsanis, C Chevillard, E Cunha-Neto, E Hirsch, JS Silva, TM Cunha
Nat Commun, 2018;9(1):1513.
Species: Mouse
Sample Types: Serum
-
Interleukin-10 produced by myeloid-derived suppressor cells is critical for the induction of Tregs and attenuation of rheumatoid inflammation in mice
Authors: MJ Park, SH Lee, EK Kim, EJ Lee, JA Baek, SH Park, SK Kwok, ML Cho
Sci Rep, 2018;8(1):3753.
Species: Mouse
Sample Types: Cell Culture Supernates
-
An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation
Authors: RG Carroll, Z Zas?ona, S Galván-Peñ, EL Koppe, DC Sévin, S Angiari, M Triantafil, K Triantafil, LK Modis, LA O'Neill
J. Biol. Chem., 2018;293(15):5509-5521.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Microsomal prostaglandin E synthase-1 gene deletion impairs neuro-immune circuitry of the cholinergic anti-inflammatory pathway in endotoxaemic mouse spleen
Authors: P Revathikum, J Estelius, U Karmakar, E Le Maître, M Korotkova, PJ Jakobsson, J Lampa
PLoS ONE, 2018;13(2):e0193210.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intravesicular Acidification Regulates Lipopolysaccharide Inflammation and Tolerance through TLR4 Trafficking
Authors: M Murase, T Kawasaki, R Hakozaki, T Sueyoshi, DDP Putri, Y Kitai, S Sato, M Ikawa, T Kawai
J. Immunol., 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross mice
Authors: J Zhang, D Malo, R Mott, JJ Panthier, X Montagutel, J Jaubert
BMC Genomics, 2018;19(1):303.
Species: Mouse
Sample Types: Serum
-
Characteristics of fucose-containing polysaccharides from submerged fermentation of�Agaricus blazei Murill
Authors: HT Wang, LC Yang, HC Yu, ML Chen, HJ Wang, TJ Lu
J Food Drug Anal, 2018;26(2):678-687.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB
Authors: Y Hayama, T Kimura, Y Takeda, S Nada, S Koyama, H Takamatsu, S Kang, D Ito, Y Maeda, M Nishide, S Nojima, H Sarashina-, T Hosokawa, Y Kinehara, Y Kato, T Nakatani, Y Nakanishi, T Tsuda, T Koba, M Okada, A Kumanogoh
J. Immunol., 2018;0(0):.
Species: Mouse
Sample Types: BALF
-
NADPH oxidases as potential pharmacological targets against increased seizure susceptibility after systemic inflammation
Authors: WY Huang, S Lin, HY Chen, YP Chen, TY Chen, KS Hsu, HM Wu
J Neuroinflammation, 2018;15(1):140.
Species: Mouse
Sample Types: Plasma
-
Viral FGARAT ORF75A promotes early events in lytic infection and gammaherpesvirus pathogenesis in mice
Authors: ND Van Skike, NK Minkah, CH Hogan, G Wu, PT Benziger, DG Oldenburg, M Kara, DM Kim-Holzap, DW White, SA Tibbetts, JB French, LT Krug
PLoS Pathog., 2018;14(2):e1006843.
Species: Mouse
Sample Types: Cell Culture Supernates
-
T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells
Authors: HR Kim, Y Mun, KS Lee, YJ Park, JS Park, JH Park, BN Jeon, CH Kim, Y Jun, YM Hyun, M Kim, SM Lee, CS Park, SH Im, CD Jun
Nat Commun, 2018;9(1):3630.
Species: Mouse
Sample Types: Cell Lysates
-
CD71+ Erythroid Suppressor Cells Promote Fetomaternal Tolerance through Arginase-2 and PDL-1
Authors: C Delyea, N Bozorgmehr, P Koleva, G Dunsmore, S Shahbaz, V Huang, S Elahi
J. Immunol., 2018;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Choline transport links macrophage phospholipid metabolism and inflammation
Authors: SA Snider, KD Margison, P Ghorbani, ND LeBlond, C O'Dwyer, JR Nunes, T Nguyen, H Xu, SA Bennett, MD Fullerton
J. Biol. Chem., 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Complement C5a Receptor 1 Exacerbates the Pathophysiology of N.�meningitidis Sepsis and Is a Potential Target for Disease Treatment
Authors: JB Herrmann, M Muensterma, L Strobel, A Schubert-U, TM Woodruff, SD Gray-Owen, A Klos, KO Johswich
MBio, 2018;9(1):.
Species: Mouse
Sample Types: Whole Blood
-
Activation of macrophage mediated host defense againstSalmonella typhimuriumbyMorus albaL
Authors: B Chang, B Koo, H Lee, JS Oh, S Kim
Food Nutr Res, 2018;62(0):.
Species: Mouse
Sample Types: Serum
-
CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma
Authors: X Ye, X Wang, R Lu, J Zhang, X Chen, G Zhou
Oncol Lett, 2018;15(6):9075-9080.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes
Authors: NC Howard, ND Marin, M Ahmed, BA Rosa, J Martin, M Bambouskov, A Sergushich, E Loginichev, N Kurepina, J Rangel-Mor, L Chen, BN Kreiswirth, RS Klein, JM Balada-Lla, JB Torrelles, GK Amarasingh, M Mitreva, MN Artyomov, FF Hsu, B Mathema, SA Khader
Nat Microbiol, 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI)
Authors: S Cicko, TC Köhler, CK Ayata, T Müller, N Ehrat, A Meyer, M Hossfeld, A Zech, F Di Virgili, M Idzko
Oncotarget, 2018;9(55):30635-30648.
Species: Mouse
Sample Types: BALF
-
Apigenin Retards Atherogenesis by Promoting ABCA1-Mediated Cholesterol Efflux and Suppressing Inflammation
Authors: K Ren, T Jiang, HF Zhou, Y Liang, GJ Zhao
Cell. Physiol. Biochem., 2018;47(5):2170-2184.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice
Authors: V Lamontain, T Schmid, D Weber-Stef, D Zeller, Z Jenei-Lanz, H Wajant, RH Straub, DN Männel
Cell. Mol. Immunol., 2018;0(0):.
Species: Mouse
Sample Types: Serum
-
Helminths-based bi-functional molecule, tuftsin-phosphorylcholine (TPC), ameliorates an established murine arthritis
Authors: M Blank, T Bashi, J Lachnish, D Ben-Ami-Sh, O Shovman, M Fridkin, M Eisenstein, A Volkov, I Barshack, Y Shoenfeld
PLoS ONE, 2018;13(8):e0200615.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Fraxinellone Attenuates Rheumatoid Inflammation in Mice
Authors: SM Jung, J Lee, SY Baek, J Lee, SG Jang, SM Hong, JS Park, ML Cho, SH Park, SK Kwok
Int J Mol Sci, 2018;19(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Kyungheechunggan-Tang-01, a New Herbal Medication, Suppresses LPS-Induced Inflammatory Responses through JAK/STAT Signaling Pathway in RAW 264.7 Macrophages
Authors: HS Han, E Jang, JS Shin, KS Inn, JH Lee, G Park, YP Jang, KT Lee
Evid Based Complement Alternat Med, 2017;2017(0):7383104.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Interspecies cathelicidin comparison reveals divergence in antimicrobial activity, TLR modulation, chemokine induction and regulation of phagocytosis
Authors: M Coorens, MR Scheenstra, EJ Veldhuizen, HP Haagsman
Sci Rep, 2017;7(0):40874.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome
Authors: V Neudecker, M Haneklaus, O Jensen, L Khailova, JC Masterson, H Tye, K Biette, P Jedlicka, KS Brodsky, ME Gerich, M Mack, AAB Robertson, MA Cooper, GT Furuta, CA Dinarello, LA O'Neill, HK Eltzschig, SL Masters, EN McNamee
J. Exp. Med., 2017;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression
Authors: MS Gresnigt, M Jaeger, RK Subbarao M, O Rasid, G Jouvion, C Fitting, WJG Melchers, TD Kanneganti, A Carvalho, O Ibrahim-Gr, FL van de Vee
Front Immunol, 2017;8(0):1777.
Species: Mouse
Sample Types: BALF
-
Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia
Authors: S Paetau, T Rolova, L Ning, CG Gahmberg
Front Mol Neurosci, 2017;10(0):431.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Effects of gold nanoparticle-based vaccine size on lymph node delivery and cytotoxic T-lymphocyte responses
Authors: S Kang, S Ahn, J Lee, JY Kim, M Choi, V Gujrati, H Kim, J Kim, EC Shin, S Jon
J Control Release, 2017;256(0):56-67.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia mediated neurodegeneration
Authors: L Shmuel-Gal, Y Klug, Z Porat, M Charni, B Zarmi, Y Shai
J. Biol. Chem., 2017;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The GLP-1 analogue lixisenatide decreases atherosclerosis in insulin-resistant mice by modulating macrophage phenotype
Authors: Á Vinué, J Navarro, A Herrero-Ce, M García-Cub, I Andrés-Bla, S Martínez-H, JT Real, JF Ascaso, H González-N
Diabetologia, 2017;0(0):.
Species: Mouse
Sample Types: Plasma
-
Proteome and secretome analysis reveals differential post-transcriptional regulation of Toll-like receptor responses
Authors: M Koppenol-R, VH Sjoelund, NP Manes, RA Gottschalk, B Dutta, ZL Benet, ID Fraser, A Nita-Lazar
Mol. Cell Proteomics, 2017;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Post-translational Activation of Glutamate Cysteine Ligase with Dimercaprol: A Novel Mechanism of Inhibiting Neuroinflammation in vitro
Authors: PB McElroy, A Sri Hari, BJ Day, M Patel
J. Biol. Chem, 2017;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunoregulatory Activity of the Natural Product Laminarin Varies Widely as a Result of Its Physical Properties
Authors: AJ Smith, B Graves, R Child, PJ Rice, Z Ma, DW Lowman, HE Ensley, KT Ryter, JT Evans, DL Williams
J. Immunol., 2017;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Paradoxical role of tumor necrosis factor on metabolic dysfunction and adipose tissue expansion in mice
Authors: LB Martins, MC Oliveira, Z Menezes-Ga, DF Rodrigues, JP Lana, LQ Vieira, MM Teixeira, AVM Ferreira
Nutrition, 2017;50(0):1-7.
Species: Mouse
Sample Types: Tissue Homogenates
-
The dataset describes: HIF-1 ? expression and LPS mediated cytokine production in MKP-1 deficient bone marrow derived murine macrophages
Authors: H Talwar, C Bauerfeld, Y Liu, L Samavati
Data Brief, 2017;14(0):56-61.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Contributions of CD8 T cells to the pathogenesis of mouse adenovirus type 1 respiratory infection
Authors: CT Molloy, JS Andonian, HM Seltzer, MC Procario, ME Watson, JB Weinberg
Virology, 2017;507(0):64-74.
Species: Mouse
Sample Types: BALF
-
NADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4
Authors: A Singh, B Koduru, C Carlisle, H Akhter, RM Liu, K Schroder, RP Brandes, DM Ojcius
Sci Rep, 2017;7(1):14346.
Species: Mouse
Sample Types: Plasma
-
Cathelicidins Inhibit Escherichia coli-Induced TLR2 and TLR4 Activation in a Viability-Dependent Manner
Authors: M Coorens, VAF Schneider, AM de Groot, A van Dijk, M Meijerink, JM Wells, MR Scheenstra, EJA Veldhuizen, HP Haagsman
J. Immunol., 2017;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Combination of a high-fat diet with sweetened condensed milk exacerbates inflammation and insulin resistance induced by each separately in mice
Authors: LN Masi, AR Martins, AR Crisma, CL do Amaral, MR Davanso, TDA Serdan, RDC da Cunha d, MM Cruz, MIC Alonso-Val, RP Torres, J Mancini-Fi, JNB Pereira, MM da Silva R, EA Liberti, SM Hirabara, R Curi
Sci Rep, 2017;7(1):3937.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Fetuin-A aggravates lipotoxicity in podocytes via interleukin-1 signaling
Authors: JM Orellana, K Kampe, F Schulze, J Sieber, AW Jehle
Physiol Rep, 2017;5(10):.
Species: Mouse
Sample Types: Serum
-
The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches
Authors: RF Espírito-S, CS Meira, RDS Costa, OP Souza Filh, AF Evangelist, GHG Trossini, GM Ferreira, EDS Velozo, CF Villarreal, MB Pereira So
PLoS ONE, 2017;12(6):e0179174.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection
Authors: M Ivin, A Dumigan, FN de Vasconc, F Ebner, M Borroni, A Kavirayani, KN Przybyszew, RJ Ingram, S Lienenklau, U Kalinke, D Stoiber, JA Bengoechea, P Kovarik
PLoS Pathog., 2017;13(11):e1006696.
Species: Mouse
Sample Types: Tissue Homogenates
-
Apolipoprotein E mimetic peptide, CN-105, improves outcomes in ischemic stroke
Authors: TM Tu, BJ Kolls, EJ Soderblom, V Cantillana, PD Ferrell, MA Moseley, H Wang, HN Dawson, DT Laskowitz
Ann Clin Transl Neurol, 2017;4(4):246-265.
Species: Mouse
Sample Types: Cell Culture Supernates
-
p-Coumaroyl Anthocyanin Mixture Isolated from Tuber Epidermis of Solanum tuberosum Attenuates Reactive Oxygen Species and Pro-inflammatory Mediators by Suppressing NF-?B and STAT1/3 Signaling in LPS-Induced RAW264.7 Macrophages
Authors: HH Lee, SG Lee, JS Shin, HY Lee, K Yoon, YW Ji, DS Jang, KT Lee
Biol. Pharm. Bull., 2017;40(11):1894-1902.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Rosmarinic acid suppresses adipogenesis, lipolysis in 3T3-L1 adipocytes, lipopolysaccharide-stimulated tumor necrosis factor-? secretion in macrophages, and inflammatory mediators in 3T3-L1 adipocytes
Authors: Y Rui, L Tong, J Cheng, G Wang, L Qin, Z Wan
Food Nutr Res, 2017;61(1):1330096.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response
Authors: M Lynch, TA Walsh, I Marszalows, AE Webb, M MacAogain, TR Rogers, H Windle, D Kelleher, MJ O'Connell, CE Loscher
BMC Evol. Biol, 2017;17(1):90.
Species: Mouse
Sample Types: Cell Culture Supernates
-
2-Phenylnaphthalene Derivatives Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Mediators by Downregulating of MAPK/NF-?B Pathways in RAW 264.7 Macrophage Cells
Authors: CF Chang, KC Liao, CH Chen
PLoS ONE, 2017;12(1):e0168945.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cerium Oxide Nanoparticles in Lung Acutely Induce Oxidative Stress, Inflammation, and DNA Damage in Various Organs of Mice
Authors: A Nemmar, P Yuvaraju, S Beegam, MA Fahim, BH Ali
Oxid Med Cell Longev, 2017;2017(0):9639035.
Species: Mouse
Sample Types: Tissue Homogenates
-
Chronic Toxoplasma gondii Infection Exacerbates Secondary Polymicrobial Sepsis
Authors: MC Souza, DM Fonseca, A Kanashiro, L Benevides, TS Medina, MS Dias, WA Andrade, G Bonfá, MAB Silva, A Gozzi, MC Borges, RT Gazzinelli, JC Alves-Filh, FQ Cunha, JS Silva
Front Cell Infect Microbiol, 2017;7(0):116.
Species: Mouse
Sample Types: Serum
-
Water-soluble chitosan inhibits nerve growth factor and attenuates allergic inflammation in mite allergen-induced allergic rhinitis
Authors: PC Chen, MH Hsieh, P Wen-ShuoKu, HF Kao, CL Hsu, JY Wang
J. Allergy Clin. Immunol., 2017;0(0):.
Species: Mouse
Sample Types: NLF
-
Erythroid Suppressor Cells Compromise Neonatal Immune Response against Bordetella pertussis
Authors: G Dunsmore, N Bozorgmehr, C Delyea, P Koleva, A Namdar, S Elahi
J. Immunol., 2017;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Inducing maternal inflammation promotes leptin production in offspring but does not improve allergic symptoms in a mouse model of allergic rhinitis
Authors: A Imai, K Satoi, E Fujimoto, K Sato
Heliyon, 2017;3(6):e00327.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The acute pulmonary and thrombotic effects of cerium oxide nanoparticles after intratracheal instillation in mice
Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, BH Ali
Int J Nanomedicine, 2017;12(0):2913-2922.
Species: Mouse
Sample Types: BALF
-
Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the Heart of Trypanosoma cruzi-Infected Mice
Authors: FN Penas, D Carta, G Dmytrenko, GA Mirkin, CP Modenutti, ÁC Cevey, MJ Rada, MG Ferlin, ME Sales, NB Goren
Front Immunol, 2017;8(0):1738.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury
Authors: JP Barrett, RJ Henry, S Villapol, BA Stoica, A Kumar, MP Burns, AI Faden, DJ Loane
J Neuroinflammation, 2017;14(1):65.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Water-Pipe Smoke Exposure-Induced Circulatory Disturbances in Mice, and the Influence of Betaine Supplementation Thereon
Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, A Oulhaj, BH Ali
Cell. Physiol. Biochem, 2017;41(3):1098-1112.
Species: Mouse
Sample Types: Plasma
-
Obesity-induced diet leads to weight gain, systemic metabolic alterations, adipose tissue inflammation, hepatic steatosis, and oxidative stress in gerbils (Meriones unguiculatus)
Authors: LL Ventura, NC Fortes, HC Santiago, MV Caliari, MA Gomes, DR Oliveira
PeerJ, 2017;5(0):e2967.
Species: Gerbil
Sample Types: Tissue Homogenates
-
Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype
MBio, 2016;7(5):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Hemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages
J Immunol, 2016;196(11):4650-62.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Polarization of macrophages towards M2 phenotype is favored by reduction in iPLA2?
J Biol Chem, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines
EBioMedicine, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunogenic Dendritic Cell Generation from Pluripotent Stem Cells by Ectopic Expression of Runx3
Authors: Istvan Szatmari
J. Immunol., 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Jucara pulp supplementation improves glucose tolerance in mice.
Authors: Oyama L, Silva F, Carnier J, de Miranda D, Santamarina A, Ribeiro E, Oller do Nascimento C, de Rosso V
Diabetol Metab Syndr, 2016;8(0):8.
Species: Mouse
Sample Types: Tissue Homogenates
-
C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils
J Immunol, 2016;196(5):2319-26.
Species: Mouse
Sample Types: BALF
-
Microbiota-inducible Innate Immune, Siderophore Binding Protein Lipocalin 2 is Critical for Intestinal Homeostasis
Cell Mol Gastroenterol Hepatol, 2016;2(4):482-498.e6.
Species: Mouse
Sample Types: Tissue Homogenates
-
Brazilian red propolis improves cutaneous wound healing suppressing inflammation-associated transcription factor NF?B
Authors: Flavia Regina Sobreira Corrêa
Biomed. Pharmacother, 2016;86(0):162-171.
Species: Mouse
Sample Types: Plasma
-
Chrysin promotes attenuation of depressive-like behavior and hippocampal dysfunction resulting from olfactory bulbectomy in mice
Authors: Silvana Peterini Boeira
Chem. Biol. Interact., 2016;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells.
Authors: Saulep-Easton D, Vincent F, Quah P, Wei A, Ting S, Croce C, Tam C, Mackay F
Leukemia, 2016;30(1):163-72.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toll-Like Receptor 2 recognizes Orientia tsutsugamushi and increases susceptibility to murine experimental scrub typhus
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Sublethal doses of Dinophysistoxin-1 and Okadaic acid stimulate secretion of inflammatory factors on innate immune cells: Negative health consequences
Authors: Miguel Del Campo
Toxicon, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization
Sci Rep, 2016;6(0):26955.
Species: Mouse
Sample Types: Tissue Homogenates
-
Immune Cell-Conditioned Media Suppress Prostate Cancer PC-3 Cell Growth Correlating With Decreased Proinflammatory/Anti-inflammatory Cytokine Ratios in the Media Using 5 Selected Crude Polysaccharides
Integr Cancer Ther, 2016;15(4):NP13-NP25.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cannabinoid receptor 2 modulates susceptibility to experimental cerebral malaria through a CCL17-dependent mechanism
J Biol Chem, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mucosal immunization confers long-term protection against intragastrically established Neospora caninum infection
Authors: Manuel Vilanova
Vaccine, 2016;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
LRP1 modulates the microglial immune response via regulation of JNK and NF-?B signaling pathways
J Neuroinflammation, 2016;13(1):304.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Repeated Activation of Lung Invariant NKT Cells Results in Chronic Obstructive Pulmonary Disease-Like Symptoms.
Authors: Tsao C, Tsao P, Chen Y, Chuang Y
PLoS ONE, 2016;11(1):e0147710.
Species: Mouse
Sample Types: BALF
-
Involvement of IL-17A-producing TCR ?? T cells in late protective immunity against pulmonary Mycobacterium tuberculosis infection
Authors: Masayuki Umemura
Immun Inflamm Dis, 2016;4(4):401-412.
Species: Mouse
Sample Types: Tissue Homogenates
-
Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis
PLoS ONE, 2016;11(5):e0154630.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CARD9 negatively regulates NLRP3-induced IL-1? production on Salmonella infection of macrophages
Nat Commun, 2016;7(0):12874.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Traditional medicine, Sobokchukeo?Tang, modulates the inflammatory response in adipocytes and macrophages
Mol Med Rep, 2016;0(0):.
Species: Mouse
Sample Types: Whole Cells
-
Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts
Authors: Arne Yndestad
Biochim. Biophys. Acta, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differential humoral and cellular immunity induced by vaccination using plasmid DNA and protein recombinant expressing the NS3 protein of dengue virus type 3
J. Biomed. Sci, 2016;23(1):85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Contribution of the Ade Resistance-Nodulation-Cell Division-Type Efflux Pumps to Fitness and Pathogenesis of Acinetobacter baumannii
Authors: Eun-Jeong Yoon
MBio, 2016;7(3):.
Species: Mouse
Sample Types: BALF
-
Proinflammatory M1 macrophages inhibit RANKL-induced osteoclastogenesis
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Caspase-2 deficiency accelerates chemically induced liver cancer in mice
Cell Death Differ, 2016;0(0):.
Species: Mouse
Sample Types: Serum
-
Indoor secondary organic aerosols formation from ozonolysis of monoterpene: An example of d-limonene with ammonia and potential impacts on pulmonary inflammations
Authors: Rujin Huang
Sci. Total Environ., 2016;0(0):.
Species: Mouse
Sample Types: BALF
-
The circadian clock regulates inflammatory arthritis
FASEB J, 2016;0(0):.
Species: Mouse
Sample Types: Serum
-
Carvacrol reduces irinotecan-induced intestinal mucositis through inhibition of inflammation and oxidative damage via TRPA1 receptor activation
Authors: Jand Venes R Medeiros
Chem. Biol. Interact., 2016;260(0):129-140.
Species: Mouse
Sample Types: Tissue Homogenates
-
NLRP12 negatively regulates proinflammatory cytokine production and host defense against Brucella abortus
Eur. J. Immunol., 2016;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge
Authors: A Savers, O Rasid, M Parlato, M Brock, G Jouvion, B Ryffel, JM Cavaillon, G Eberl, O Ibrahim-Gr
PLoS ONE, 2016;11(4):e0153829.
Species: Mouse
Sample Types: Tissue Homogenates
-
Poly-N-acetyl glucosamine production by Staphylococcus epidermidis cells increases their in vivo pro-inflammatory effect
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Types: Tissue Secretion
-
Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition
PLoS Pathog, 2016;12(5):e1005644.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.
Authors: Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, Birrell M, Saijo S, Mostowy S, Shaunak S, Armstrong-James D
EMBO Mol Med, 2015;7(3):240-58.
Species: Mouse
Sample Types: Cell Culture Supernates
-
De novo-induced self-antigen-specific Foxp3+ regulatory T cells impair the accumulation of inflammatory dendritic cells in draining lymph nodes.
Authors: Alissafi T, Hatzioannou A, Ioannou M, Sparwasser T, Grun J, Grutzkau A, Verginis P
J Immunol, 2015;194(12):5812-24.
-
Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens.
Authors: Kortman G, Mulder M, Richters T, Shanmugam N, Trebicka E, Boekhorst J, Timmerman H, Roelofs R, Wiegerinck E, Laarakkers C, Swinkels D, Bolhuis A, Cherayil B, Tjalsma H
Eur J Immunol, 2015;45(9):2553-67.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Anti-Inflammatory Effects of beta2-Receptor Agonists Salbutamol and Terbutaline Are Mediated by MKP-1.
Authors: Keranen T, Hommo T, Hamalainen M, Moilanen E, Korhonen R
PLoS ONE, 2015;11(2):e0148144.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Human beta-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid.
Authors: Semple F, MacPherson H, Webb S, Kilanowski F, Lettice L, McGlasson S, Wheeler A, Chen V, Millhauser G, Melrose L, Davidson D, Dorin J
PLoS Genet, 2015;11(12):e1005673.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model.
Authors: Gillgrass A, Chew M, Krneta T, Ashkar A
BMC Cancer, 2015;15(0):293.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from Endophytic Bacteria.
Authors: Todd D, Gulledge T, Britton E, Oberhofer M, Leyte-Lugo M, Moody A, Shymanovich T, Grubbs L, Juzumaite M, Graf T, Oberlies N, Faeth S, Laster S, Cech N
PLoS ONE, 2015;10(5):e0124276.
Species: Mouse
Sample Types: Cell Culture Supernates
-
DCIR maintains bone homeostasis by regulating IFN-gamma production in T cells.
Authors: Maruhashi T, Kaifu T, Yabe R, Seno A, Chung S, Fujikado N, Iwakura Y
J Immunol, 2015;194(12):5681-91.
Species: Mouse
Sample Types: Tissue Homogenates
-
KIM-1-mediated phagocytosis reduces acute injury to the kidney.
Authors: Yang L, Brooks C, Xiao S, Sabbisetti V, Yeung M, Hsiao L, Ichimura T, Kuchroo V, Bonventre J
J Clin Invest, 2015;125(4):1620-36.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Obesity increases airway hyperresponsiveness via the TNF-alpha pathway and treating obesity induces recovery.
Authors: Kim J, Sohn J, Lee J, Park J
PLoS ONE, 2015;10(2):e0116540.
Species: Mouse
Sample Types: Tissue Homogenates
-
C1q Deficiency Promotes Pulmonary Vascular Inflammation and Enhances the Susceptibility of the Lung Endothelium to Injury.
Authors: Shah D, Romero F, Zhu Y, Duong M, Sun J, Walsh K, Summer R
J Biol Chem, 2015;290(49):29642-51.
Species: Mouse
Sample Types: BALF
-
Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolism.
Authors: Tan Z, Xie N, Cui H, Moellering D, Abraham E, Thannickal V, Liu G
J Immunol, 2015;194(12):6082-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice.
Authors: Li Y, Chen H, Bannick N, Henry M, Holm A, Metwali A, Urban J, Rothman P, Weiner G, Blazar B, Elliott D, Ince M
J Immunol, 2015;194(3):1011-20.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Authors: Coll R, Robertson A, Chae J, Higgins S, Munoz-Planillo R, Inserra M, Vetter I, Dungan L, Monks B, Stutz A, Croker D, Butler M, Haneklaus M, Sutton C, Nunez G, Latz E, Kastner D, Mills K, Masters S, Schroder K, Cooper M, O'Neill L
Nat Med, 2015;21(3):248-55.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action.
Authors: Wang H, Sethi G, Loke W, Sim M
PLoS ONE, 2015;10(9):e0138009.
Species: Mouse
Sample Types: Plasma
-
Adaptor Protein-3-Mediated Trafficking of TLR2 Ligands Controls Specificity of Inflammatory Responses but Not Adaptor Complex Assembly.
Authors: Petnicki-Ocwieja T, Kern A, Killpack T, Bunnell S, Hu L
J Immunol, 2015;195(9):4331-40.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection.
Authors: Zhao Y, Olonisakin T, Xiong Z, Hulver M, Sayeed S, Yu M, Gregory A, Kochman E, Chen B, Mallampalli R, Sun M, Silverstein R, Stolz D, Shapiro S, Ray A, Ray P, Lee J
Mucosal Immunol, 2015;8(4):896-905.
Species: Mouse
Sample Types: Tissue Homogenates
-
Endoplasmic reticulum stress-induced IRE1alpha activation mediates cross-talk of GSK-3beta and XBP-1 to regulate inflammatory cytokine production.
Authors: Kim S, Joe Y, Kim H, Kim Y, Jeong S, Pae H, Ryter S, Surh Y, Chung H
J Immunol, 2015;194(9):4498-506.
Species: Mouse
Sample Types: Serum
-
The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory.
Authors: Yoshida K, Maekawa T, Zhu Y, Renard-Guillet C, Chatton B, Inoue K, Uchiyama T, Ishibashi K, Yamada T, Ohno N, Shirahige K, Okada-Hatakeyama M, Ishii S
Nat Immunol, 2015;16(10):1034-43.
Species: Mouse
Sample Types: Serum
-
A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis.
Authors: Bernard N, Finlay C, Tannahill G, Cassidy J, O'Neill L, Mills K
Mucosal Immunol, 2015;8(5):982-92.
Species: Mouse
Sample Types: Tissue Homogenates
-
Consistent inhibition of cyclooxygenase drives macrophages towards the inflammatory phenotype.
Authors: Na Y, Yoon Y, Son D, Jung D, Gu G, Seok S
PLoS ONE, 2015;10(2):e0118203.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling.
Authors: Wu Y, Wu Y, Mo S, Hsiao H, He Y, Lai M
J Immunol, 2015;195(6):2612-23.
-
Effects of High-Intensity Swimming on Lung Inflammation and Oxidative Stress in a Murine Model of DEP-Induced Injury.
Authors: Avila L, Bruggemann T, Bobinski F, da Silva M, Oliveira R, Martins D, Mazzardo-Martins L, Duarte M, de Souza L, Dafre A, Vieira R, Santos A, Bonorino K, Hizume Kunzler D
PLoS ONE, 2015;10(9):e0137273.
Species: Mouse
Sample Types: Tissue Homogenates
-
Liver X receptor-dependent inhibition of microglial nitric oxide synthase 2.
Authors: Secor McVoy J, Oughli H, Oh U
J Neuroinflammation, 2015;12(0):27.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.
Authors: Brown A, Murphy A, Lalor S, Leech J, O'Keeffe K, Mac Aogain M, O'Halloran D, Lacey K, Tavakol M, Hearnden C, Fitzgerald-Hughes D, Humphreys H, Fennell J, van Wamel W, Foster T, Geoghegan J, Lavelle E, Rogers T, McLoughlin R
PLoS Pathog, 2015;11(11):e1005226.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice.
Authors: Douglas T, Champagne C, Morizot A, Lapointe J, Saleh M
J Immunol, 2015;195(5):2365-73.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Protection against Streptococcus pneumoniae lung infection after nasopharyngeal colonization requires both humoral and cellular immune responses.
Authors: Wilson R, Cohen J, Jose R, de Vogel C, Baxendale H, Brown J
Mucosal Immunol, 2015;8(3):627-39.
Species: Mouse
Sample Types: Tissue Homogenates
-
Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat Feeding.
Authors: Jovicic N, Jeftic I, Jovanovic I, Radosavljevic G, Arsenijevic N, Lukic M, Pejnovic N
PLoS ONE, 2015;10(7):e0134089.
Species: Mouse
Sample Types: Tissue Homogenates
-
Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2.
Authors: Fieber C, Janos M, Koestler T, Gratz N, Li X, Castiglia V, Aberle M, Sauert M, Wegner M, Alexopoulou L, Kirschning C, Chen Z, von Haeseler A, Kovarik P
PLoS ONE, 2015;10(3):e0119727.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Sm10.3, a member of the micro-exon gene 4 (MEG-4) family, induces erythrocyte agglutination in vitro and partially protects vaccinated mice against Schistosoma mansoni infection.
Authors: Martins V, Morais S, Pinheiro C, Assis N, Figueiredo B, Ricci N, Alves-Silva J, Caliari M, Oliveira S
PLoS Negl Trop Dis, 2014;8(3):e2750.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lack of platelet-activating factor receptor protects mice against diet-induced adipose inflammation and insulin-resistance despite fat pad expansion.
Authors: Menezes-Garcia Z, Oliveira M, Lima R, Soriani F, Cisalpino D, Botion L, Teixeira M, Souza D, Ferreira A
Obesity (Silver Spring), 2014;22(3):663-72.
Species: Mouse
Sample Types: Tissue Homogenates
-
No Impairment in host defense against Streptococcus pneumoniae in obese CPEfat/fat mice.
Authors: Mancuso P, O Brien E, Prano J, Goel D, Aronoff D
PLoS ONE, 2014;9(9):e106420.
Species: Mouse
Sample Types: BALF
-
Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia.
Authors: Lei B, Mace B, Dawson H, Warner D, Laskowitz D, James M
PLoS ONE, 2014;9(7):e103969.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells.
Authors: Gleeson E, O'Donnell J, Hams E, Ni Ainle F, Kenny B, Fallon P, Preston R
Haematologica, 2014;99(1):185-93.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Leukotriene B4 enhances the generation of proinflammatory microRNAs to promote MyD88-dependent macrophage activation.
Authors: Wang Z, Filgueiras L, Wang S, Serezani A, Peters-Golden M, Jancar S, Serezani C
J Immunol, 2014;192(5):2349-56.
Species: Mouse
Sample Types: Cell Culture Supernates
-
miR-27a regulates inflammatory response of macrophages by targeting IL-10.
Authors: Xie N, Cui H, Banerjee S, Tan Z, Salomao R, Fu M, Abraham E, Thannickal V, Liu G
J Immunol, 2014;193(1):327-34.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Sustained Na+/H+ exchanger activation promotes gliotransmitter release from reactive hippocampal astrocytes following oxygen-glucose deprivation.
Authors: Cengiz P, Kintner D, Chanana V, Yuan H, Akture E, Kendigelen P, Begum G, Fidan E, Uluc K, Ferrazzano P, Sun D
PLoS ONE, 2014;9(1):e84294.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The small GTPase Arf6 is essential for the Tram/Trif pathway in TLR4 signaling.
Authors: Van Acker T, Eyckerman S, Vande Walle L, Gerlo S, Goethals M, Lamkanfi M, Bovijn C, Tavernier J, Peelman F
J Biol Chem, 2014;289(3):1364-76.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toll-like receptor 9 deficiency protects mice against Pseudomonas aeruginosa lung infection.
Authors: Benmohamed F, Medina M, Wu Y, Maschalidi S, Jouvion G, Guillemot L, Chignard M, Manoury B, Touqui L
PLoS ONE, 2014;9(3):e90466.
Species: Mouse
Sample Types: BALF
-
An iron-acquisition-deficient mutant of Corynebacterium pseudotuberculosis efficiently protects mice against challenge.
Authors: Ribeiro D, Rocha F, Leite K, Soares S, Silva A, Portela R, Meyer R, Miyoshi A, Oliveira S, Azevedo V, Dorella F
Vet Res, 2014;45(0):28.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice.
Authors: Takaoka, Yuki, Goto, Shigeru, Nakano, Toshiaki, Tseng, Hui-Peng, Yang, Shih-Min, Kawamoto, Seiji, Ono, Kazuhisa, Chen, Chao-Lon
Sci Rep, 2014;4(0):5204.
Species: Mouse
Sample Types: Serum
-
Artesunate reduces serum lipopolysaccharide in cecal ligation/puncture mice via enhanced LPS internalization by macrophages through increased mRNA expression of scavenger receptors.
Authors: Li, Bin, Yu, Mengchen, Pan, Xichun, Ren, Chuanlia, Peng, Wei, Li, Xiaoli, Jiang, Weiwei, Zheng, Jiang, Zhou, Hong
Int J Mol Sci, 2014;15(1):1143-61.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lipopolysaccharide induces inflammatory hyperalgesia triggering a TLR4/MyD88-dependent cytokine cascade in the mice paw.
Authors: Calil I, Zarpelon A, Guerrero A, Alves-Filho J, Ferreira S, Cunha F, Cunha T, Verri W
PLoS ONE, 2014;9(3):e90013.
Species: Mouse
Sample Types: Tissue Homogenates
-
MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity.
Authors: Salama A, Fichou N, Allard M, Dubreil L, De Beaurepaire L, Viel A, Jegou D, Bosch S, Bach J
PLoS ONE, 2014;9(9):e106153.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.
Authors: Hams, Emily, Armstrong, Michelle, Barlow, Jillian, Saunders, Sean P, Schwartz, Christia, Cooke, Gordon, Fahy, Ruairi J, Crotty, Thomas B, Hirani, Nikhil, Flynn, Robin J, Voehringer, David, McKenzie, Andrew N, Donnelly, Seamas C, Fallon, Padraic
Proc Natl Acad Sci U S A, 2014;111(1):367-72.
Species: Mouse
Sample Types: Tissue Homogenates
-
Metabolic profile response to administration of epigallocatechin-3-gallate in high-fat-fed mice.
Authors: Moreno M, De Laquila R, Okuda M, Lira F, de Souza G, de Souza C, Telles M, Ribeiro E, do Nascimento C, Oyama L
Diabetol Metab Syndr, 2014;6(1):84.
Species: Mouse
Sample Types: Tissue Homogenates
-
S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model.
Authors: Kim H, Chang K, Ha T, Kim J, Ha S, Shin K, Moon C, Nacken W, Kim H, Suh Y
PLoS ONE, 2014;9(2):e88924.
Species: Mouse
Sample Types: Tissue Homogenates
-
Pulmonary immune responses to 2009 pandemic influenza A (H1N1) virus in mice.
Authors: Lv J, Wang D, Hua Y, Pei S, Wang J, Hu W, Wang X, Jia N, Jiang Q
BMC Infect Dis, 2014;14(0):197.
Species: Mouse
Sample Types: Tissue Homogenates
-
Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection.
PLoS ONE, 2014;9(12):e114884.
Species: Mouse
Sample Types: Tissue Homogenates
-
The innate immune response elicited by Group A Streptococcus is highly variable among clinical isolates and correlates with the emm type.
Authors: Dinis M, Plainvert C, Kovarik P, Longo M, Fouet A, Poyart C
PLoS ONE, 2014;9(7):e101464.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.
Authors: Dowling J, Becker C, Bourke N, Corr S, Connolly D, Quinn S, Pandolfi P, Mansell A, O'Neill L
J Biol Chem, 2014;289(10):6429-37.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The glycosylated Rv1860 protein of mycobacterium tuberculosis inhibits dendritic cell mediated TH1 and TH17 polarization of T cells and abrogates protective immunity conferred by BCG.
Authors: Satchidanandam V, Kumar N, Jumani R, Challu V, Elangovan S, Khan N
PLoS Pathog, 2014;10(6):e1004176.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toll-like receptor 9 mediated responses in cardiac fibroblasts.
Authors: Ohm I, Alfsnes K, Belland Olsen M, Ranheim T, Sandanger O, Dahl T, Aukrust P, Finsen A, Yndestad A, Vinge L
PLoS ONE, 2014;9(8):e104398.
-
Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM.
Authors: Assi H, Espinosa J, Suprise S, Sofroniew M, Doherty R, Zamler D, Lowenstein P, Castro M
PLoS ONE, 2014;9(5):e96318.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Developmental onset of bilirubin-induced neurotoxicity involves Toll-like receptor 2-dependent signaling in humanized UDP-glucuronosyltransferase1 mice.
Authors: Yueh M, Chen S, Nguyen N, Tukey R
J Biol Chem, 2014;289(8):4699-709.
Species: Mouse
Sample Types: Serum
-
Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
Authors: Dreymueller D, Martin C, Schumacher J, Groth E, Boehm J, Reiss L, Uhlig S, Ludwig A
J Immunol, 2014;192(2):722-31.
Species: Mouse
Sample Types: BALF
-
A2B adenosine receptors prevent insulin resistance by inhibiting adipose tissue inflammation via maintaining alternative macrophage activation.
Authors: Csoka B, Koscso B, Toro G, Kokai E, Virag L, Nemeth Z, Pacher P, Bai P, Hasko G
Diabetes, 2014;63(3):850-66.
Species: Mouse
Sample Types: Plasma
-
Protective or deleterious role of scavenger receptors SR-A and CD36 on host resistance to Staphylococcus aureus depends on the site of infection.
Authors: Blanchet C, Jouvion G, Fitting C, Cavaillon J, Adib-Conquy M
PLoS ONE, 2014;9(1):e87927.
Species: Mouse
Sample Types: BALF
-
Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis.
Authors: Larson-Casey J, Murthy S, Ryan A, Carter A
J Biol Chem, 2014;289(52):36204-19.
Species: Mouse
Sample Types: BALF
-
Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity.
Authors: Barra, Nicole G, Palanivel, Rengasam, Denou, Emmanuel, Chew, Marianne, Gillgrass, Amy, Walker, Tina D, Kong, Josh, Richards, Carl D, Jordana, Manel, Collins, Stephen, Trigatti, Bernardo, Holloway, Alison C, Raha, Sandeep, Steinberg, Gregory, Ashkar, Ali A
PLoS ONE, 2014;9(12):e114799.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Endogenous oils derived from human adipocytes are potent adjuvants that promote IL-1?-dependent inflammation.
Authors: Tynan, Graham A, Hearnden, Claire H, Oleszycka, Ewa, Lyons, Claire L, Coutts, Graham, O'Connell, Jean, Corrigan, Michelle, Lynch, Lydia, Campbell, Matthew, Callanan, John J, Mok, Kenneth, Geoghegan, Justin, O'Farrelly, Cliona, Allan, Stuart M, Roche, Helen M, O'Shea, Donal B, Lavelle, Ed C
Diabetes, 2014;63(6):2037-50.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Vitamin d deficiency reduces the immune response, phagocytosis rate, and intracellular killing rate of microglial cells.
Authors: Djukic M, Onken M, Schutze S, Redlich S, Gotz A, Hanisch U, Bertsch T, Ribes S, Hanenberg A, Schneider S, Bollheimer C, Sieber C, Nau R
Infect Immun, 2014;82(6):2585-94.
Species: Mouse
Sample Types: Cell Culture Supernates
-
RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.
Authors: Rigby R, Webb L, Mackenzie K, Li Y, Leitch A, Reijns M, Lundie R, Revuelta A, Davidson D, Diebold S, Modis Y, MacDonald A, Jackson A
EMBO J, 2014;33(6):542-58.
Species: Mouse
Sample Types: Cell Culture Supernates
-
FcgammaRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis.
Authors: Clatworthy M, Harford S, Mathews R, Smith K
Proc Natl Acad Sci U S A, 2014;111(50):17971-6.
-
ARF6 inhibition stabilizes the vasculature and enhances survival during endotoxic shock.
Authors: Davis C, Zhu W, Gibson C, Bowman-Kirigin J, Sorensen L, Ling J, Sun H, Navankasattusas S, Li D
J Immunol, 2014;192(12):6045-52.
Species: Mouse
Sample Types: Plasma
-
Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 by macrophages and increases the resistance of mice against infections.
Authors: Redlich S, Ribes S, Schutze S, Nau R
J Neuroinflammation, 2014;11(0):108.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease.
Authors: Noelker C, Morel L, Osterloh A, Alvarez-Fischer D, Lescot T, Breloer M, Gold M, Oertel W, Henze C, Michel P, Dodel R, Lu L, Hirsch E, Hunot S, Hartmann A
J Neuroinflammation, 2014;11(0):86.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Murine lung injury caused by Leptospira interrogans glycolipoprotein, a specific Na/K-ATPase inhibitor.
Authors: Goncalves-de-Albuquerque C, Burth P, Silva A, de Moraes I, Oliveira F, Santelli R, Freire A, de Lima G, da Silva E, da Silva C, Morandi V, Bozza P, Younes-Ibrahim M, de Castro Faria Neto H, de Castro Faria M
Respir Res, 2014;15(0):93.
Species: Mouse
Sample Types: BALF
-
Anti-inflammatory effects of Perilla frutescens leaf extract on lipopolysaccharide-stimulated RAW264.7 cells.
Authors: Huang B, Lin C, Chen Y, Kao S
Mol Med Rep, 2014;10(2):1077-83.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Role of OGR1 in myeloid-derived cells in prostate cancer.
Authors: Yan, L, Singh, L S, Zhang, L, Xu, Y
Oncogene, 2014;33(2):157-64.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection.
Authors: Teijaro J, Walsh K, Rice S, Rosen H, Oldstone M
Proc Natl Acad Sci U S A, 2014;111(10):3799-804.
Species: Mouse
Sample Types: BALF
-
Lysosomes integrate metabolic-inflammatory cross-talk in primary macrophage inflammasome activation.
Authors: Weber K, Schilling J
J Biol Chem, 2014;289(13):9158-71.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Etanercept administration to neonatal SH3BP2 knock-in cherubism mice prevents TNF-alpha-induced inflammation and bone loss.
Authors: Yoshitaka T, Ishida S, Mukai T, Kittaka M, Reichenberger E, Ueki Y
J Bone Miner Res, 2014;29(5):1170-82.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Acerola (Malpighia emarginata DC.) juice intake protects against alterations to proteins involved in inflammatory and lipolysis pathways in the adipose tissue of obese mice fed a cafeteria diet.
Authors: Dias F, Leffa D, Daumann F, Marques S, Luciano T, Possato J, de Santana A, Neves R, Rosa J, Oyama L, Rodrigues B, de Andrade V, de Souza C, de Lira F
Lipids Health Dis, 2014;13(0):24.
Species: Mouse
Sample Types: Tissue Homogenates
-
Tristetraprolin mediates anti-inflammatory effect of carbon monoxide against DSS-induced colitis.
Authors: Joe Y, Uddin M, Zheng M, Kim H, Chen Y, Yoon N, Cho G, Park J, Chung H
PLoS ONE, 2014;9(2):e88776.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Gene and protein expression in response to different growth temperatures and oxygen availability in Burkholderia thailandensis.
Authors: Peano C, Chiaramonte F, Motta S, Pietrelli A, Jaillon S, Rossi E, Consolandi C, Champion O, Michell S, Freddi L, Falciola L, Basilico F, Garlanda C, Mauri P, De Bellis G, Landini P
PLoS ONE, 2014;9(3):e93009.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy.
Authors: Walsh K, Teijaro J, Brock L, Fremgen D, Collins P, Rosen H, Oldstone M
J Virol, 2014;88(11):6281-93.
Species: Mouse
Sample Types: BALF
-
LPS from bovine serum albumin drives TNF-alpha release during ex-vivo placenta perfusion experiments, contaminates the perfusion system but can be effectively removed by oxidative cleaning.
Authors: Vasanthan T, Rochow N, Mian F, Codini T, DeFrance B, Fusch G, Samiee-Zafarghandy S, Fusch C
Placenta, 2014;35(12):1095-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Development and characterization of a long-term murine model of Streptococcus pneumoniae infection of the lower airways.
Authors: Haste L, Hulland K, Bolton S, Yesilkaya H, McKechnie K, Andrew P
Infect Immun, 2014;82(8):3289-98.
Species: Mouse
Sample Types: BALF
-
Peripheral inflammation is associated with remote global gene expression changes in the brain.
Authors: Thomson, Carolyn, McColl, Alison, Cavanagh, Jonathan, Graham, Gerard J
J Neuroinflammation, 2014;11(0):73.
Species: Mouse
Sample Types: Plasma
-
MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity.
Authors: Benasciutti E, Mariani E, Oliva L, Scolari M, Perilli E, Barras E, Milan E, Orfanelli U, Fazzalari N, Campana L, Capobianco A, Otten L, Particelli F, Acha-Orbea H, Baruffaldi F, Faccio R, Sitia R, Reith W, Cenci S
J Bone Miner Res, 2014;29(2):290-303.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
Authors: Ataide M, Andrade W, Zamboni D, Wang D, Souza M, Franklin B, Elian S, Martins F, Pereira D, Reed G, Fitzgerald K, Golenbock D, Gazzinelli R
PLoS Pathog, 2014;10(1):e1003885.
Species: Mouse
Sample Types: Whole Blood
-
Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection.
Authors: Brant F, Miranda A, Esper L, Rodrigues D, Kangussu L, Bonaventura D, Soriani F, Pinho V, Souza D, Rachid M, Weiss L, Tanowitz H, Teixeira M, Teixeira A, Machado F
Infect Immun, 2014;82(8):3127-40.
Species: Mouse
Sample Types: Tissue Homogenates
-
PPAR-gamma/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis.
Authors: Ferreira A, Sisti F, Sonego F, Wang S, Filgueiras L, Brandt S, Serezani A, Du H, Cunha F, Alves-Filho J, Serezani C
J Immunol, 2014;192(5):2357-65.
Species: Mouse
Sample Types: Serum
-
Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infection.
Authors: Crotty Alexander, Laura E, Marsh, Brenda J, Timmer, Anjuli M, Lin, Ann E, Zainabadi, Kayvan, Czopik, Agnieszk, Guarente, Leonard, Nizet, Victor
PLoS ONE, 2013;8(12):e84481.
Species: Mouse
Sample Types: Plasma
-
The chemotherapeutic agent DMXAA as a unique IRF3-dependent type-2 vaccine adjuvant.
Authors: Tang, Choon Ki, Aoshi, Taiki, Jounai, Nao, Ito, Junichi, Ohata, Keiichi, Kobiyama, Kouji, Dessailly, Benoit H, Kuroda, Etsushi, Akira, Shizuo, Mizuguchi, Kenji, Coban, Cevayir, Ishii, Ken J
PLoS ONE, 2013;8(3):e60038.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Milano summer particulate matter (PM10) triggers lung inflammation and extra pulmonary adverse events in mice.
Authors: Farina F, Sancini G, Battaglia C, Tinaglia V, Mantecca P, Camatini M, Palestini P
PLoS ONE, 2013;8(2):e56636.
Species: Mouse
Sample Types: BALF
-
CD3(-)NK1.1(+) cells aid in the early induction of a Th1 response to an attaching and effacing enteric pathogen.
Authors: Reid-Yu S, Small C, Coombes B
Eur J Immunol, 2013;43(10):2638-49.
Species: Mouse
Sample Types: Tissue Homogenates
-
The lung inflammation and skeletal muscle wasting induced by subchronic cigarette smoke exposure are not altered by a high-fat diet in mice.
Authors: Hansen, Michelle, Chen, Hui, Jones, Jessica, Langenbach, Shenna Y, Vlahos, Ross, Gualano, Rosa C, Morris, Margaret, Anderson, Gary P
PLoS ONE, 2013;8(11):e80471.
Species: Mouse
Sample Types: Tissue Homogenates
-
Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones.
Authors: Beynon A, Brown M, Wright R, Rees M, Sheldon I, Davies J
J Neuroinflammation, 2013;10(0):40.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Syntaxin binding protein 1 is not required for allergic inflammation via IgE-mediated mast cell activation.
Authors: Wu Z, MacNeil A, Berman J, Lin T
PLoS ONE, 2013;8(3):e58560.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NLRP3 inflammasome activation by Paracoccidioides brasiliensis.
Authors: Tavares A, Magalhaes K, Almeida R, Correa R, Burgel P, Bocca A
PLoS Negl Trop Dis, 2013;7(12):e2595.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunization with a MOMP-based vaccine protects mice against a pulmonary Chlamydia challenge and identifies a disconnection between infection and pathology.
Authors: O'Meara C, Armitage C, Harvie M, Timms P, Lycke N, Beagley K
PLoS ONE, 2013;8(4):e61962.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice.
Authors: Waddell A, Ahrens R, Tsai Y, Sherrill J, Denson L, Steinbrecher K, Hogan S
J Immunol, 2013;190(9):4773-85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mesenchymal stem cells inhibit cutaneous radiation-induced fibrosis by suppressing chronic inflammation.
Authors: Horton J, Hudak K, Chung E, White A, Scroggins B, Burkeen J, Citrin D
Stem Cells, 2013;31(10):2231-41.
Species: Mouse
Sample Types: Tissue Homogenates
-
Toll-like receptor 6 senses Mycobacterium avium and is required for efficient control of mycobacterial infection.
Authors: Marinho F, de Paula R, Mendes A, de Almeida L, Gomes M, Carvalho N, Oliveira F, Caliari M, Oliveira S
Eur J Immunol, 2013;43(9):2373-85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Sulfatide attenuates experimental Staphylococcus aureus sepsis through a CD1d-dependent pathway.
Authors: Kwiecinski J, Rhost S, Lofbom L, Blomqvist M, Mansson J, Cardell S, Jin T
Infect Immun, 2013;81(4):1114-20.
Species: Mouse
Sample Types: Plasma
-
Genetic deletion of the HIF-1alpha isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model.
Authors: Georgiev P, Belikoff B, Hatfield S, Ohta A, Sitkovsky M, Lukashev D
Eur J Immunol, 2013;43(3):655-66.
Species: Mouse
Sample Types: Serum
-
Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model.
Authors: Everitt, Aaron R, Clare, Simon, McDonald, Jacqueli, Kane, Leanne, Harcourt, Katherin, Ahras, Malika, Lall, Amar, Hale, Christin, Rodgers, Angela, Young, Douglas, Haque, Ashraful, Billker, Oliver, Tregoning, John S, Dougan, Gordon, Kellam, Paul
PLoS ONE, 2013;8(11):e80723.
Species: Mouse
Sample Types: BALF
-
Adenosine augments IL-10-induced STAT3 signaling in M2c macrophages.
Authors: Koscso B, Csoka B, Kokai E, Nemeth Z, Pacher P, Virag L, Leibovich S, Hasko G
J Leukoc Biol, 2013;94(6):1309-15.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toll-like receptor 6 plays an important role in host innate resistance to Brucella abortus infection in mice.
Authors: de Almeida L, Macedo G, Marinho F, Gomes M, Corsetti P, Silva A, Cassataro J, Giambartolomei G, Oliveira S
Infect Immun, 2013;81(5):1654-62.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NF-kappaB-targeted anti-inflammatory activity of Prunella vulgaris var. lilacina in macrophages RAW 264.7.
Authors: Hwang Y, Lee E, Kim H, Hwang K
Int J Mol Sci, 2013;14(11):21489-503.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Bee venom and its component apamin as neuroprotective agents in a Parkinson disease mouse model.
Authors: Alvarez-Fischer D, Noelker C, Vulinovic F, Grunewald A, Chevarin C, Klein C, Oertel W, Hirsch E, Michel P, Hartmann A
PLoS ONE, 2013;8(4):e61700.
Species: Mouse
Sample Types: Tissue Homogenates
-
Continuous and discontinuous cigarette smoke exposure differentially affects protective Th1 immunity against pulmonary tuberculosis.
Authors: Shaler C, Horvath C, McCormick S, Jeyanathan M, Khera A, Zganiacz A, Kasinska J, Stampfli M, Xing Z
PLoS ONE, 2013;8(3):e59185.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IRAK-M mediates Toll-like receptor/IL-1R-induced NFkappaB activation and cytokine production.
Authors: Zhou H, Yu M, Fukuda K, Im J, Yao P, Cui W, Bulek K, Zepp J, Wan Y, Kim T, Yin W, Ma V, Thomas J, Gu J, Wang J, DiCorleto P, Fox P, Qin J, Li X
EMBO J, 2013;32(4):583-96.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis.
Authors: Park Y, Yoon S, Suh H, Kim D, Park J, Jung H, Kim T, Yoon S, Min J, Na H, Lee S, Lee H, Lee Y, Lee H, Choi I
PLoS Pathog, 2013;9(10):e1003646.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Calcineurin-Rcan1 interaction contributes to stem cell factor-mediated mast cell activation.
Authors: Wu Z, Li Y, MacNeil A, Junkins R, Berman J, Lin T
J Immunol, 2013;191(12):5885-94.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mannose receptor 1 mediates cellular uptake and endosomal delivery of CpG-motif containing oligodeoxynucleotides.
Authors: Moseman, Annie Pa, Moseman, E Ashley, Schworer, Stephen, Smirnova, Irina, Volkova, Tatyana, von Andrian, Ulrich, Poltorak, Alexande
J Immunol, 2013;191(11):5615-24.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages.
Authors: Gonzalez Y, Doens D, Santamaria R, Ramos M, Restrepo C, Barros de Arruda L, Lleonart R, Gutierrez M, Fernandez P
PLoS ONE, 2013;8(12):e84107.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Altered regulation of Toll-like receptor responses impairs antibacterial immunity in the allergic lung.
Authors: Habibzay, M, Saldana, J I, Goulding, J, Lloyd, C M, Hussell, T
Mucosal Immunol, 2012;5(5):524-34.
Species: Mouse
Sample Types: BALF
-
Macrophage Dectin-1 Expression Is Controlled by Leukotriene B4 via a GM-CSF/PU.1 Axis.
Authors: Serezani CH, Kane S, Collins L
J. Immunol., 2012;189(2):906-15.
Species: Mouse
Sample Types: BALF
-
Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury.
Authors: Sato A, Ohtaki H, Tsumuraya T, Song D, Ohara K, Asano M, Iwakura Y, Atsumi T, Shioda S
J Neuroinflammation, 2012;9(0):65.
Species: Mouse
Sample Types: Tissue Homogenates
-
TLR9 and MyD88 are crucial for the development of protective immunity to malaria.
Authors: Gowda NM, Wu X, Gowda DC
J. Immunol., 2012;188(10):5073-85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dok2 mediates the CD200Fc attenuation of Abeta-induced changes in glia.
Authors: Lyons A, Downer E, Costello D, Murphy N, Lynch M
J Neuroinflammation, 2012;9(0):107.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Alveolar Macrophages Play a Key Role in Cockroach-Induced Allergic Inflammation via TNF-alpha Pathway.
Authors: Kim J, Sohn J, Choi J, Lee J, Hong C, Lee J, Park J
PLoS ONE, 2012;7(10):e47971.
Species: Mouse
Sample Types: Tissue Homogenates
-
The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems.
Authors: Chuquimia OD, Petursdottir DH, Rahman MJ, Hartl K, Singh M, Fernandez C
PLoS ONE, 2012;7(2):e32125.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands.
Authors: Munich S, Sobo-Vujanovic A, Buchser W, Beer-Stolz D, Vujanovic N
Oncoimmunology, 2012;1(7):1074-1083.
Species: Mouse
Sample Types: Cell Lysates
-
IL-10 mediated regulation of liver inflammation during acute murine cytomegalovirus infection.
Authors: Gaddi, Pamela J, Crane, Meredith, Kamanaka, Masahito, Flavell, Richard, Yap, George S, Salazar-Mather, Thais P
PLoS ONE, 2012;7(8):e42850.
Species: Mouse
Sample Types: Serum
-
Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
Infect. Immun., 2012;80(1):100-9.
Species: Mouse
Sample Types: Serum
-
Immune Modulation Mediated by Cryptococcal Laccase Promotes Pulmonary Growth and Brain Dissemination of Virulent Cryptococcus neoformans in Mice.
Authors: Qiu Y, Davis M, Dayrit J, Hadd Z, Meister D, Osterholzer J, Williamson P, Olszewski M
PLoS ONE, 2012;7(10):e47853.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Influence of hypoxia-inducible factor 1-alpha on dendritic cell differentiation and migration.
Authors: Kohler T, Reizis B, Johnson RS, Weighardt H, Forster I
Eur. J. Immunol., 2012;42(5):1226-36.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.
J. Immunol., 2012;189(4):1911-9.
Species: Mouse
Sample Types: Serum
-
Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via alphavbeta1 integrin.
Authors: Kang S, Okuno T, Takegahara N, Takamatsu H, Nojima S, Kimura T, Yoshida Y, Ito D, Ohmae S, You DJ, Toyofuku T, Jang MH, Kumanogoh A
J. Immunol., 2011;188(3):1108-16.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue.
Authors: Nicholls HT, Kowalski G, Kennedy DJ
Diabetes, 2011;60(4):1100-10.
Species: Mouse
Sample Types: Plasma
-
Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia.
Authors: Steinwede K, Tempelhof O, Bolte K, Maus R, Bohling J, Ueberberg B, Langer F, Christman JW, Paton JC, Ask K, Maharaj S, Kolb M, Gauldie J, Welte T, Maus UA
J. Immunol., 2011;187(10):5346-56.
Species: Mouse
Sample Types: BALF
-
Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection.
Authors: Teijaro JR, Walsh KB, Cahalan S, Fremgen DM, Roberts E, Scott F, Martinborough E, Peach R, Oldstone MB, Rosen H
Cell, 2011;146(6):980-91.
Species: Mouse
Sample Types: BALF
-
CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition.
Authors: Barber DL, Mayer-Barber KD, Feng CG
J. Immunol., 2011;186(3):1598-607.
Species: Mouse
Sample Types: BALF
-
Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis.
Authors: Machado GB, de Oliveira AV, Saliba AM, de Lima CD, Suassuna JH, Plotkowski MC
Respir. Res., 2011;12(0):104.
Species: Mouse
Sample Types: BALF
-
Leukocyte ADAM17 Regulates Acute Pulmonary Inflammation.
Authors: Arndt PG, Strahan B, Wang Y, Long C, Horiuchi K, Walcheck B
PLoS ONE, 2011;6(5):e19938.
Species: Mouse
Sample Types: BALF
-
Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.
Authors: Le Goffic R, Leymarie O, Chevalier C, Rebours E, Da Costa B, Vidic J, Descamps D, Sallenave JM, Rauch M, Samson M, Delmas B
PLoS Pathog., 2011;7(8):e1002202.
Species: Mouse
Sample Types: BALF
-
Lung-targeted overexpression of the NF-kappaB member RelB inhibits cigarette smoke-induced inflammation.
Authors: McMillan DH, Baglole CJ, Thatcher TH, Maggirwar S, Sime PJ, Phipps RP
Am. J. Pathol., 2011;179(1):125-33.
Species: Mouse
Sample Types: BALF
-
Tyrosine kinase 2 controls IL-1beta production at the translational level.
Authors: Radwan M, Stiefvater R, Grunert T, Sharif O, Miller I, Marchetti-Deschmann M, Allmaier G, Gemeiner M, Knapp S, Kovarik P, Muller M, Strobl B
J. Immunol., 2010;185(6):3544-53.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Mucosal delivery of human papillomavirus pseudovirus-encapsidated plasmids improves the potency of DNA vaccination.
Authors: Graham BS, Kines RC, Corbett KS, Nicewonger J, Roberts JN, Schiller JT, Buck CB
Mucosal Immunol, 2010;3(5):475-86.
Species: Mouse
Sample Types: BALF
-
Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity.
Authors: Sellge G, Magalhaes JG, Konradt C, Fritz JH, Salgado-Pabon W, Eberl G, Bandeira A, Di Santo JP, Sansonetti PJ, Phalipon A
J. Immunol., 2010;184(4):2076-85.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Interleukin-15 contributes to the regulation of murine adipose tissue and human adipocytes.
Authors: Barra NG, Reid S, MacKenzie R
Obesity (Silver Spring), 2010;18(8):1601-7.
Species: Mouse
Sample Types: Serum
-
A novel mechanism of cytokine release in phagocytes induced by aggretin, a snake venom C-type lectin protein, through CLEC-2 ligation.
Authors: Chang CH, Chung CH, Hsu CC, Huang TY, Huang TF
J. Thromb. Haemost., 2010;8(11):2563-70.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling.
Authors: Graham BB, Mentink-Kane MM, El-Haddad H
Am. J. Pathol., 2010;177(3):1549-61.
Species: Mouse
Sample Types: Tissue Homogenates
-
Toll-like receptor 4 mediates the response of epithelial and stromal cells to lipopolysaccharide in the endometrium.
Authors: Sheldon IM, Roberts MH,
PLoS ONE, 2010;5(9):e12906.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis.
Authors: Matsuda N, Yamamoto S, Yokoo H, Tobe K, Hattori Y
Crit. Care Med., 2009;37(10):2791-9.
Species: Mouse
Sample Types: Serum
-
Age-associated aggravation of clinical disease after primary metapneumovirus infection of BALB/c mice.
Authors: Darniot M, Pitoiset C, Petrella T, Aho S, Pothier P, Manoha C
J. Virol., 2009;83(7):3323-32.
Species: Mouse
Sample Types: BALF
-
TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia.
Authors: Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S
J. Immunol., 2009;183(3):2027-36.
Species: Mouse
Sample Types: Tissue Homogenates
-
Oxidized alpha1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema.
Authors: Li Z, Alam S, Wang J, Sandstrom CS, Janciauskiene S, Mahadeva R
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(2):L388-400.
Species: Mouse
Sample Types: BALF
-
Modulation of macrophage infiltration and inflammatory activity by the phosphatase SHP-1 in virus-induced demyelinating disease.
Authors: Christophi GP, Hudson CA, Panos M, Gruber RC, Massa PT
J. Virol., 2009;83(2):522-39.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema.
Authors: Couillin I, Vasseur V, Charron S, Gasse P, Tavernier M, Guillet J, Lagente V, Fick L, Jacobs M, Coelho FR, Moser R, Ryffel B
J. Immunol., 2009;183(12):8195-202.
Species: Mouse
Sample Types: BALF
-
Mesenchymal stem cells produce Wnt isoforms and TGF-beta1 that mediate proliferation and procollagen expression by lung fibroblasts.
Authors: Salazar KD, Lankford SM, Brody AR
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(5):L1002-11.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Regulation of HSP70 on activating macrophages using PDT-induced apoptotic cells.
Authors: Zhou F, Xing D, Chen WR
Int. J. Cancer, 2009;125(6):1380-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.
Authors: Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P
J. Immunol., 2009;183(4):2642-9.
Species: Mouse
Sample Types: BALF
-
Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse.
Authors: Wang S, Wu D, Matthan NR, Lamon-Fava S, Lecker JL, Lichtenstein AH
Atherosclerosis, 2009;204(1):147-55.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.
Authors: Jaffre F, Bonnin P, Callebert J, Debbabi H, Setola V, Doly S, Monassier L, Mettauer B, Blaxall BC, Launay JM, Maroteaux L
Circ. Res., 2009;104(1):113-23.
Species: Mouse
Sample Types: Plasma
-
The long pentraxin PTX3 is crucial for tissue inflammation after intestinal ischemia and reperfusion in mice.
Authors: Souza DG, Amaral FA, Fagundes CT, Coelho FM, Arantes RM, Sousa LP, Matzuk MM, Garlanda C, Mantovani A, Dias AA, Teixeira MM
Am. J. Pathol., 2009;174(4):1309-18.
Species: Mouse
Sample Types: Serum
-
Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent.
Authors: Doz E, Noulin N, Boichot E, Guenon I, Fick L, Le Bert M, Lagente V, Ryffel B, Schnyder B, Quesniaux VF, Couillin I
J. Immunol., 2008;180(2):1169-78.
Species: Mouse
Sample Types: BALF
-
VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways.
Authors: Tiwari N, Wang CC, Brochetta C, Ke G, Vita F, Qi Z, Rivera J, Soranzo MR, Zabucchi G, Hong W, Blank U
Blood, 2008;111(7):3665-74.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Amelioration of delayed-type hypersensitivity responses by IL-27 administration.
Authors: Miyazaki Y, Shimanoe Y, Wang S, Yoshida H
Biochem. Biophys. Res. Commun., 2008;373(3):397-402.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Decreased pathology and prolonged survival of human DC-SIGN transgenic mice during mycobacterial infection.
Authors: Schaefer M, Reiling N, Fessler C, Stephani J, Taniuchi I, Hatam F, Yildirim AO, Fehrenbach H, Walter K, Ruland J, Wagner H, Ehlers S, Sparwasser T
J. Immunol., 2008;180(10):6836-45.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Direct B cell stimulation by dendritic cells in a mouse model of lupus.
Authors: Wan S, Zhou Z, Duan B, Morel L
Arthritis Rheum., 2008;8(0):1741-50.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Surfactant protein D alters allergic lung responses in mice and human subjects.
Authors: Brandt EB, Mingler MK, Stevenson MD, Wang N, Khurana Hershey GK, Whitsett JA, Rothenberg ME
J. Allergy Clin. Immunol., 2008;121(5):1140-1147.e2.
Species: Mouse
Sample Types: BALF
-
IFN-gamma synergizes with LPS to induce nitric oxide biosynthesis through glycogen synthase kinase-3-inhibited IL-10.
Authors: Lin CF, Tsai CC, Huang WC, Wang CY, Tseng HC, Wang Y, Kai JI, Wang SW, Cheng YL
J. Cell. Biochem., 2008;105(3):746-55.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection.
Authors: Macedo GC, Magnani DM, Carvalho NB, Bruna-Romero O, Gazzinelli RT, Oliveira SC
J. Immunol., 2008;180(2):1080-7.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia.
Authors: Lembo A, Pelletier M, Iyer R, Timko M, Dudda JC, West TE, Wilson CB, Hajjar AM, Skerrett SJ
J. Immunol., 2008;180(11):7574-81.
Species: Mouse
Sample Types: Tissue Homogenates
-
Amelioration of experimental autoimmune encephalomyelitis in IL-4Ralpha-/- mice implicates compensatory up-regulation of Th2-type cytokines.
Authors: Gaupp S, Cannella B, Raine CS
Am. J. Pathol., 2008;173(1):119-29.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis.
Authors: Kaya Z, Goser S, Buss SJ, Leuschner F, Ottl R, Li J, Volkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA
Circulation, 2008;118(20):2063-72.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Divergent effects of hypoxia on dendritic cell functions.
Authors: Mancino A, Schioppa T, Larghi P, Pasqualini F, Nebuloni M, Chen IH, Sozzani S, Austyn JM, Mantovani A, Sica A
Blood, 2008;112(9):3723-34.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature.
Authors: Coelho FM, Pinho V, Amaral FA, Sachs D, Costa VV, Rodrigues DH, Vieira AT, Silva TA, Souza DG, Bertini R, Teixeira AL, Teixeira MM
Arthritis Rheum., 2008;58(8):2329-37.
Species: Mouse
Sample Types: Tissue Homogenates
-
Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia.
Authors: Schell JB, Crane CA, Smith MF, Roberts MR
J. Neuroimmunol., 2007;189(1):75-87.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Involvement of vitronectin in lipopolysaccaride-induced acute lung injury.
Authors: Tsuruta Y, Park YJ, Siegal GP, Liu G, Abraham E
J. Immunol., 2007;179(10):7079-86.
Species: Mouse
Sample Types: Tissue Homogenates
-
Dectin-1 interaction with Mycobacterium tuberculosis leads to enhanced IL-12p40 production by splenic dendritic cells.
Authors: Rothfuchs AG, Bafica A, Feng CG, Egen JG, Williams DL, Brown GD, Sher A
J. Immunol., 2007;179(6):3463-71.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation.
Authors: Obregon D, Hou H, Bai Y, Nikolic WV, Mori T, Luo D, Zeng J, Ehrhart J, Fernandez F, Morgan D, Giunta B, Town T, Tan J
Neurobiol. Dis., 2007;29(2):336-53.
Species: Mouse
Sample Types: Plasma
-
The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion.
Authors: Kim N, Saudemont A, Webb L, Camps M, Ruckle T, Hirsch E, Turner M, Colucci F
Blood, 2007;110(9):3202-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Dietary fish oil increases the number of splenic macrophages secreting TNF-alpha and IL-10 but decreases the secretion of these cytokines by splenic T cells from mice.
Authors: Petursdottir DH, Hardardottir I
J. Nutr., 2007;137(3):665-70.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells.
Authors: Vanhoutte F, Paget C, Breuilh L, Fontaine J, Vendeville C, Goriely S, Ryffel B, Faveeuw C, Trottein F
Immunol. Lett., 2007;116(1):86-94.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Lung dendritic cells elicited by Fms-like tyrosine 3-kinase ligand amplify the lung inflammatory response to lipopolysaccharide.
Authors: von Wulffen W, Steinmueller M, Herold S, Marsh LM, Bulau P, Seeger W, Welte T, Lohmeyer J, Maus UA
Am. J. Respir. Crit. Care Med., 2007;176(9):892-901.
Species: Mouse
Sample Types: BALF
-
Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis.
Authors: Hwang SA, Wilk KM, Budnicka M, Olsen M, Bangale YA, Hunter RL, Kruzel ML, Actor JK
Vaccine, 2007;25(37):6730-43.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells.
Authors: Sugiyama K, Shirai R, Mukae H, Ishimoto H, Nagata T, Sakamoto N, Ishii H, Nakayama S, Yanagihara K, Mizuta Y, Kohno S
Clin. Exp. Immunol., 2007;147(3):540-6.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
Immunity, 2007;26(4):445-59.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis.
Authors: Hegde A, Zhang H, Moochhala SM, Bhatia M
J. Leukoc. Biol., 2007;82(3):678-85.
Species: Mouse
Sample Types: Plasma
-
Deletion of TLR5 results in spontaneous colitis in mice.
Authors: Vijay-Kumar M, Sanders CJ, Taylor RT, Kumar A, Aitken JD, Sitaraman SV, Neish AS, Uematsu S, Akira S, Williams IR, Gewirtz AT
J. Clin. Invest., 2007;117(12):3909-21.
Species: Mouse
Sample Types: Serum
-
Dendritic cell expression of OX40 ligand acts as a costimulatory, not polarizing, signal for optimal Th2 priming and memory induction in vivo.
Authors: Jenkins SJ, Perona-Wright G, Worsley AG, Ishii N, MacDonald AS
J. Immunol., 2007;179(6):3515-23.
Species: Mouse
Sample Types: Cell Culture Supernates
-
A synthetic analog of alpha-galactosylceramide induces macrophage activation via the TLR4-signaling pathways.
Authors: Hung LC, Lin CC, Hung SK, Wu BC, Jan MD, Liou SH, Fu SL
Biochem. Pharmacol., 2007;73(12):1957-70.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The differential effect of Eriobotrya japonica hydrophilic leaf extract on cytokines production and modulation.
Authors: Matalka KZ, Ali D, Khawad AE, Qa'dan F
Cytokine, 2007;40(3):235-40.
Species: Mouse
Sample Types: Serum
-
ABCC transporter inhibition reduces zymosan-induced peritonitis.
Authors: Leite DF, Echevarria-Lima J, Ferreira SC, Calixto JB, Rumjanek VM
J. Leukoc. Biol., 2007;82(3):630-7.
Species: Mouse
Sample Types: Tissue Secretion
-
The EGF receptor is required for efficient liver regeneration.
Authors: Natarajan A, Wagner B, Sibilia M
Proc. Natl. Acad. Sci. U.S.A., 2007;104(43):17081-6.
Species: Mouse
Sample Types: Serum
-
Glucose-6-phosphate dehydrogenase deficiency and the inflammatory response to endotoxin and polymicrobial sepsis.
Authors: Wilmanski J, Villanueva E, Deitch EA, Spolarics Z
Crit. Care Med., 2007;35(2):510-8.
Species: Mouse
Sample Types: Plasma
-
Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection.
Authors: Cheng W, Shivshankar P, Li Z, Chen L, Yeh IT, Zhong G
Infect. Immun., 2007;76(2):515-22.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The acylation state of mycobacterial lipomannans modulates innate immunity response through toll-like receptor 2.
Authors: Gilleron M, Nigou J, Nicolle D, Quesniaux V, Puzo G
Chem. Biol., 2006;13(1):39-47.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Exogenous IL-12 suppresses experimental autoimmune encephalomyelitis (EAE) by tuning IL-10 and IL-5 levels in an IFN-gamma-dependent way.
Authors: Berghmans N, Dillen C, Heremans H
J. Neuroimmunol., 2006;176(1):63-75.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Immunity induced with a Salmonella enterica serovar Enteritidis live vaccine is regulated by Th1-cell-dependent cellular and humoral effector mechanisms in susceptible BALB/c mice.
Authors: Lehmann J, Springer S, Werner CE, Lindner T, Bellmann S, Straubinger RK, Selbitz HJ, Alber G
Vaccine, 2006;24(22):4779-93.
Species: Mouse
Sample Types: Serum
-
TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
Authors: Higgins SC, Jarnicki AG, Lavelle EC, Mills KH
J. Immunol., 2006;177(11):7980-9.
Species: Mouse
Sample Types: Cell Culture Supernates
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Effects of dexamethazone on LPS-induced activationand migration of mouse dendritic cells revealed by a genome-wide transcriptional analysis.
Authors: Vizzardelli C, Pavelka N, Luchini A, Zanoni I, Bendickson L, Pelizzola M, Beretta O, Foti M, Granucci F, Nilsen-Hamilton M, Ricciardi-Castagnoli P
Eur. J. Immunol., 2006;36(6):1504-15.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Muscle wasting and impaired muscle regeneration in a murine model of chronic pulmonary inflammation.
Authors: Langen RC, Schols AM, Kelders MC, van der Velden JL, Wouters EF, Janssen-Heininger YM
Am. J. Respir. Cell Mol. Biol., 2006;35(6):689-96.
Species: Mouse
Sample Types: BALF
-
The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production.
Authors: Powell JM, Sonnenfeld G
J. Interferon Cytokine Res., 2006;26(1):34-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differential involvement of TLR2 and TLR4 in host survival during pulmonary infection with Chlamydia pneumoniae.
Authors: Rodriguez N, Wantia N, Fend F, Durr S, Wagner H, Miethke T
Eur. J. Immunol., 2006;36(5):1145-55.
Species: Mouse
Sample Types: Tissue Homogenates
-
Effects of dexamethasone on macrophage migration inhibitory factor production in sepsis.
Authors: Bruhn A, Verdant C, Vercruysse V, Su F, Vray B, Vincent JL
Shock, 2006;26(2):169-73.
Species: Mouse
Sample Types: Plasma
-
Tissue inhibitor of metalloproteinase-1 deficiency amplifies acute lung injury in bleomycin-exposed mice.
Authors: Kim KH, Burkhart K, Chen P, Frevert CW, Randolph-Habecker J, Hackman RC, Soloway PD, Madtes DK
Am. J. Respir. Cell Mol. Biol., 2005;33(3):271-9.
Species: Mouse
Sample Types: BALF
-
Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis.
Authors: Carpenter KJ, Hogaboam CM
Infect. Immun., 2005;73(11):7198-207.
Species: Mouse
Sample Types: Tissue Homogenates
-
An essential role for non-bone marrow-derived cells in control of Pseudomonas aeruginosa pneumonia.
Authors: Hajjar AM, Harowicz H, Liggitt HD, Fink PJ, Wilson CB, Skerrett SJ
Am. J. Respir. Cell Mol. Biol., 2005;33(5):470-5.
Species: Mouse
Sample Types: Tissue Homogenates
-
Both hemopoietic and resident cells are required for MyD88-dependent pulmonary inflammatory response to inhaled endotoxin.
Authors: Noulin N, Quesniaux VF, Schnyder-Candrian S, Schnyder B, Maillet I, Robert T, Vargaftig BB, Ryffel B, Couillin I
J. Immunol., 2005;175(10):6861-9.
Species: Mouse
Sample Types: BALF
-
MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo.
Authors: Delale T, Paquin A, Asselin-Paturel C, Dalod M, Brizard G, Bates EE, Kastner P, Chan S, Akira S, Vicari A, Biron CA, Trinchieri G, Briere F
J. Immunol., 2005;175(10):6723-32.
Species: Mouse
Sample Types: Serum
-
Impaired inflammatory angiogenesis, but not leukocyte influx, in mice lacking TNFR1.
Authors: Barcelos LS, Talvani A, Teixeira AS, Vieira LQ, Cassali GD, Andrade SP, Teixeira MM
J. Leukoc. Biol., 2005;78(2):352-8.
Species: Mouse
Sample Types: Complex Sample Type
-
Long-term control of Mycobacterium bovis BCG infection in the absence of Toll-like receptors (TLRs): investigation of TLR2-, TLR6-, or TLR2-TLR4-deficient mice.
Authors: Nicolle D, Fremond C, Pichon X, Bouchot A, Maillet I, Ryffel B, Quesniaux VJ
Infect. Immun., 2004;72(12):6994-7004.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of spaceflight conditions.
Authors: Aviles H, Belay T, Vance M, Sun B, Sonnenfeld G
J. Appl. Physiol., 2004;97(4):1437-44.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Severe pancreatitis with exocrine destruction and increased islet neogenesis in mice with suppressor of cytokine signaling-1 deficiency.
Authors: Chong MM, Thomas HE, Kay TW
Am. J. Pathol., 2004;165(3):913-21.
Species: Mouse
Sample Types: Serum
-
Specific engagement of TLR4 or TLR3 does not lead to IFN-beta-mediated innate signal amplification and STAT1 phosphorylation in resident murine alveolar macrophages.
Authors: Punturieri A, Alviani RS, Polak T, Copper P, Sonstein J, Curtis JL
J. Immunol., 2004;173(2):1033-42.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection.
Authors: Zamboni DS, Campos MA, Torrecilhas AC, Kiss K, Samuel JE, Golenbock DT, Lauw FN, Roy CR, Almeida IC, Gazzinelli RT
J. Biol. Chem., 2004;279(52):54405-15.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88.
Authors: Fremond CM, Yeremeev V, Nicolle DM, Jacobs M, Quesniaux VF, Ryffel B
J. Clin. Invest., 2004;114(12):1790-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Toll-like receptor 2 is required for optimal control of Listeria monocytogenes infection.
Authors: Torres D, Barrier M, Bihl F, Quesniaux VJ, Maillet I, Akira S, Ryffel B, Erard F
Infect. Immun., 2004;72(4):2131-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Acylation state of the phosphatidylinositol hexamannosides from Mycobacterium bovis bacillus Calmette Guerin and mycobacterium tuberculosis H37Rv and its implication in Toll-like receptor response.
Authors: Gilleron M, Quesniaux VF, Puzo G
J. Biol. Chem., 2003;278(32):29880-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Adenoviral infection decreases mortality from lipopolysaccharide-induced liver failure via induction of TNF-alpha tolerance.
Authors: Yarovinsky TO, Powers LS, Butler NS, Bradford MA, Monick MM, Hunninghake GW
J. Immunol., 2003;171(5):2453-60.
Species: Mouse
Sample Types: Serum
-
Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody.
Authors: O'Garra A
J. Exp. Med., 2002;196(4):541-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CpG-DNA aided cross-presentation of soluble antigens by dendritic cells.
Authors: O'Keeffe M
Eur. J. Immunol., 2002;32(8):2356-64.
Species: Mouse
Sample Types: Serum
-
A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization.
Authors: van der Kleij D, Latz E, Brouwers JF, Kruize YC, Schmitz M, Kurt-Jones EA, Espevik T, de Jong EC, Kapsenberg ML, Golenbock DT, Tielens AG, Yazdanbakhsh M
J. Biol. Chem., 2002;277(50):48122-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.
Authors: Alexopoulou, L, Holt, A C, Medzhitov, R, Flavell, R A
Nature, 2001;413(6857):732-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease.
Authors: Evans C, Miners J, Piva G, Willis C, Heard D, Kidd E, Good M, Kehoe P
Acta Neuropathol, 0;139(3):485-502.
Species: Mouse
Sample Types: Tissue Homogenates
-
TLR2 deletion promotes arthritis through reduction of IL-10.
Authors: Huang Q, Koessler R, Birkett R, Perlman H, Xing L, Pope R
J Leukoc Biol, 0;93(5):751-9.
Species: Mouse
Sample Types: Cell Culture Supernates
FAQs
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Does the Mouse TNF-alpha DuoSet ELISA recognize the monomer and/or trimer form of TNF-alpha?
TNF-alpha self-dissociates to monomers in the picomolar range. The assay standard curve concentration is from approximately 2 - 118 femtomolar, the range in which self-dissociation is expected to occur. This supports that the assay detects monomeric TNF-alpha.
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Kit perfectly detected TNF-a in polarised M1 like macrophages
RAW cells stimulated with 10ng/mL LPS for 24 hours
The evaluation was conducted in seric samples from adult C57BL/6J mice after 12-weeks treatment with a high-fat diet (60 % calories from fat). Results were accurate and showed a potent TNF-a levels in the serum samples.
We tested TNFa production in culture supernatant of mouse macrophages induced by Staphylococcus aureus (SA) lipoprotein after 4 h treatment. As expected, SA lipoprotein induces significant production of TNFa.
Mouse BAL fluid diluted 1:50 and incubated overnight at 4 degrees C.
Briefly, 96‐well microplates were incubated with the capture antibody overnight, at room temperature. Following coating, plates were blocked with 1% BSA in PBS and then washed with 0.05% Tween 20 in PBS. Samples and standards were then added and allowed to incubate for 2 hr while shaking at room temperature. Plates were then washed and allowed to incubate with the biotinylated goat anti‐mouse TNFα detection antibody for 2 hr while shaking at room temperature, then washed again. Finally, we incubated the plates with Streptavidin‐HRP and a substrate solution for 30‐min each. A stop solution of 1N H2SO4 was added just prior to plate reading. The optical‐density of each well was determined using a microplate reader, set to 450 nm.