Dehydrogenases

Dehydrogenases are oxidoreductase enzymes. They catalyze the oxidation of a substrate through the transfer of hydrogen (hydride) to an acceptor (or co-enzyme). Dehydrogenases are classified according to the donor group, e.g. alcohol or aldehyde, and the acceptor. Acceptors include nicotinamide adenine dinucleotide (NAD+ or NADH), nicotinamide adenine dinucleotide phosphate (NADP+ or NADPH), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and cytochromes. Dehydrogenase enzymes are important in multiple physiological processes, including normal cellular metabolism as part of the TCA (Krebs) cycle, or in cancer metabolism in the glycolysis pathway.

Dehydrogenase Products

11β-Hydroxysteroid Dehydrogenase

Isocitrate Dehydrogenase 1 (IDH1)

Aldehyde Dehydrogenases (View All)

Lactate Dehydrogenase A

Dihydroorotate Dehydrogenase

Other Dehydrogenases

Dehydrogenase Gene Data

GeneSpeciesGene SymbolGene Accession No.Protein Accession No.
11-HSDHumanHSD11B1NM_005525P28845
MouseHsd11b1NM_008288P50172
RatHsd11b1NM_017080Q6TUH9
DHODHHumanDHODHNM_001361Q02127
MouseDhodhNM_020046O35435
RatDhodhNM_001008553Q63707
IMP1HumanIMPDH1NM_000883P20839
MouseImpdh1NM_011829P50096
RatImpdh1NM_001108619XP_342651
IMP2HumanIMPDH2NM_000884P12268
MouseImpdh2NM_011830P24547
RatImpdh2NM_199099Q6P9U9
PDHα1HumanPDHA1NM_000284P08559
MousePdha1NM_008810P35486
RatPdha1NM_001004072P26284
PDHα2HumanPDHA2NM_005390P29803
MousePdha2NM_008811P35487
RatPdha2NM_053994Q06437
PDHβHumanPDHBNM_000925P11177
MousePdhbNM_024221Q9D051
RatPdhbNM_001007620P49432