Osteogenic Stem Cells
Osteogenic stem cells, also termed osteoprogenitor cells, are derived from mesenchymal stem cells (MSCs) and can differentiate into specialized cells including osteoblasts and chondroblasts. Osteoblasts generate bone matrix proteins which promote bone development and remodeling, while chondroblasts generate the cartilage matrix and maintain the extracellular matrix (ECM). Osteogenic stem cells are primarily responsible for bone repair and growth, and errors in these cells contribute to bone-related diseases such as osteoarthritis, dwarfism, and osteoporosis. Osteogenic stem cells therefore have potential for clinical applications such as bone grafting.
R&D Systems and its partner brands offer a variety of tools and targets for stem cell research.
Related Products
| Catalog Number | Product Name | Function |
|---|---|---|
| 2840 | AICAR | AMPK activator; promotes osteogenic differentiation of bone marrow-derived MSCs. |
| 4504 | Chaetocin | Promotes osteogenic differentiation in MSCs. |
| 5495 | CW 008 | PKA signaling activator; promotes osteogenesis from human MSCs. |
| 4551 | Purmorphamine | Smo receptor agonist; induces differentiation of mesenchymal progenitor cells into osteoblasts. |