Retinal Stem Cells
Retinal stem cells (RSCs) differentiate into the various complex retinal cells formed in the optic vesicle of the eye during embryonic development. These stem cells play a key role in vision by generating the neurons and Müller glia of the mature retina, and a small group of RSCs remain at the edge of the retina throughout the lifespan. RSCs have therapeutic potential as a clinical application for the treatment of retinal degenerative diseases, such as macular degeneration, which contribute to vision loss and blindness.
Discover the variety of products and tools offered by R&D Systems and its partner brands for the robust research of RSCs.
Related Products
| Catalog Number | Product Name | Function |
|---|---|---|
| 5329 | CKI 7 dihydrochloride | CK1 inhibitor; induces retinal cell differentiation from human ESCs and iPSCs. |
| 2634 | DAPT | Preferentially induces cone photoreceptor subtype in retinal cell differentiation. |
| 4011 | EC 23 | Synthetic retinoid; induces neural differentiation of hESCs. |
| 4093 | Hydrocortisone | Promotes maturation of RPE cells differentiated from hPSCs. |
| 3532 | endo-IWR 1 | Can be used in the generation of RPE cells from hPSCs; Wnt/β-catenin singaling inhibitor. |
| 0695 | Retinoic acid | Promotes maturation of retinal organoids; retinoic acid receptor agonist. |
| 6666 | T3 | Specifies cone cell subtype in retinal cell differentiation. |