687 results for "CD117/c-kit" in Products

CD117/c-kit Products

CD117, also known as c-kit and SCF R, is the cellular receptor for Stem Cell Factor (SCF), also named c-kit ligand, mast cell growth factor, and steel factor. This receptor-ligand system plays essential roles in germ cell development, melanogenesis, hematopoiesis, and oncogenesis. CD117 is expressed on lymphoid, myeloid,  erythroid, and megakaryocyte progenitors, NK cells, germ cells, melanocytes, glial cells, vascular smooth muscle cells, placenta, and epithelial cells. Altered levels and mutations in CD117 are associated with several types of cancer including lung, breast, gastrointestinal stromal, and germ cell tumors.

Reactivity: Human
Human Luminex Discovery Assay

Build your own Luminex Assay with our Luminex Assay Customization Tool

Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies

Reactivity: Human
Detection of Human Receptor Tyrosine Kinase Phosphorylation in KATO-III Cell Line.
(2)
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Reactivity: Human, Mouse
Details: Rat IgG2b Kappa Monoclonal Clone #2B8
Applications: IHC, Flow, ICC/IF, IP
Flow Cytometry: CD117/c-kit Antibody (2B8) - BSA Free [NB100-77477]
(4)
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Reactivity: Human, Mouse, Guinea Pig
Details: Rat IgG2b Kappa Monoclonal Clone #ACK2
Applications: IHC, WB, Flow, ICC/IF, IP
Immunohistochemistry Whole-Mount: CD117/c-kit Antibody (ACK2) - BSA Free [NBP1-43359]
(3)
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Reactivity: Mouse
Details: Rat IgG2A Monoclonal Clone #180627
Applications: IHC, WB, Flow, CyTOF-ready
CD117/c-kit antibody in Mouse Brain by Immunohistochemistry (IHC-Fr).
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Reactivity: Human
Source: Sf 21 (baculovirus)
Accession #: P10721
Applications: Bioactivity
R&D Systems Recombinant Proteins and Enzymes
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VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3

Alternate Names: Semaxinib
Chemical Name: 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
Purity: ≥98%
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
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Reactivity: Human, Mouse
Details: Rat IgG2b Kappa Monoclonal Clone #2B8
Applications: IHC, Flow, ICC/IF, IP, CyTOF-ready
Flow Cytometry: CD117/c-kit Antibody (2B8) - Azide and BSA Free [NBP2-80624]
(3)
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, Simple Western
Detection of Human CD117/c-kit antibody by Western Blot.
(2)
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, Simple Western
Detection of Human Phospho-CD117/ c-kit (Y730) antibody by Western Blot.
(2)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #CL1657
Applications: IHC, WB
Western Blot: CD117/c-kit Antibody (CL1657) [NBP2-52975]
(6)
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Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #OTI2B12
Applications: IHC, WB
Western Blot: CD117/c-kit Antibody (OTI2B12) [NBP2-45508]
(13)
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Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #OTI2B12
Applications: IHC, WB
Western Blot: CD117/c-kit Antibody (OTI2B12)Azide and BSA Free [NBP2-71076]
(13)
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Reactivity: Human
Details: Mouse IgG2A Monoclonal Clone #CL1667
Applications: IHC, WB
Western Blot: CD117/c-kit Antibody (CL1667) [NBP2-34487]
(6)
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Reactivity: Human
Assay Range: 31.2-2000 pg/mL
Applications: ELISA
Human CD117 / c-kit ELISA Standard Curve
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Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit

Alternate Names: Gleevec,CGP 57148B
Chemical Name: 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate
Purity: ≥98%
Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC
Immunohistochemistry-Paraffin: CD117/c-kit Antibody [NBP1-85593]
(4)
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Reactivity: Human
Details: Mouse IgG2A Monoclonal Clone #CL1667
Applications: IHC, WB
CD117/c-kit Antibody (CL1667) - Azide and BSA Free Western Blot: CD117/c-kit Antibody [NBP3-44073]
(6)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #CL1657
Applications: IHC, WB
CD117/c-kit Antibody (CL1657) - Azide and BSA Free Immunohistochemistry-Paraffin: CD117/c-kit Antibody [NBP3-44075]
(6)
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c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation

Chemical Name: N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]urea
Purity: ≥97%
c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation
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Reactivity: Human
Applications: ELISA
R&D Systems DuoSet ELISAs
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