Human/Mouse Adropin Antibody

Adropin (from the gene energy homeostasis-associated protein, ENHO) is a 76 amino acid peptide hormone encoded by the gene ENHO. Adropin levels are regulated by nutrition; a high fat diet in lean C57BL/6J mice produced rapid increase in ENHO expression. It is preferentially expressed in brain and has cardiovascular and metabolic roles in the periphery. Adropin plays a role in metabolic homeostasis, fatty acids metabolism control, insulin resistance prevention, Dyslipidemia and impaired glucose tolerance.  Adropin level is thought to be a factor in obesity because it plays a role in regulating carbohydrate, lipid and protein metabolisms by moderating glucose-mediated insulin release. High plasma levels of Adropin are associated with heart failure and body mass index. Adropin has also been shown to preserve the blood brain barrier and improve neuronal function after intracerebral hemorrhage in mice.