Proteins for Coronavirus Research

Proteins for Coronavirus Research

The pace of COVID-19 research and drug development speeds along at an unprecedented pace as the scientific community searches for a cure. At R&D Systems, we understand the importance of quality recombinant proteins and enzymes with documented bioactivity and consistent performance for studying SARS-CoV-2 and other coronaviruses. You can trust R&D Systems proteins for your coronavirus research.

Coronavirus Proteins

Protein Species Source Tag Catalog # Bioactivity
SARS-CoV-2 S Protein RBD SARS-CoV-2 HEK293 Fc 10499-CV Binds ACE-2 (Catalog # 933-ZN)
SARS-CoV-2 Nucleocapsid Protein SARS-CoV-2 Sf21 His 10474-CV N/A
SARS-CoV-2 Papain-like Protease SARS-CoV-2 E. coli No tag E-611 Cleaves Ubiquitin-Rhodamine 110 (Catalog # U-555)
SARS-CoV-2 3CL Protease SARS-CoV-2 E. coli No tag Please inquire In Development

Coronavirus Proteins

Receptor recognition

Coronavirus binding to a cell surface receptor is a key mechanism of infection and a major focus of therapeutic research. Using proteins that are bioactive and have the correct conformation is critical for binding and drug development studies. Every protein listed below is QC tested for bioactivity and lot-to-lot consistency.

ACE-2 Receptor Recognition

Protein Species Source Tag Catalog # Bioactivity
ACE-2 Human NS0 His 933-ZN Cleaves the fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH (Catalog # ES007)
Mouse CHO His 3437-ZN
Rat NS0 His 4516-ZN
DPPIV Human NS0 His 9168-SE Cleaves the fluorogenic peptide substrate, Gly-Pro-7-amido-4-methylcoumarin (GP-AMC)
Mouse NS0 His 954-SE
Cyno HEK293 His 9637-SE
Aminopeptidase N/CD13 Human NS0 His 3815-ZN Cleaves the fluorogenic peptide substrate, Ala-7-amido-4-methylcoumarin (Ala-AMC)
Mouse NS0 His 2335-ZN
CEACAM-1 Human NS0 His 2244-CM Inhibits IL-2 secretion by T cells
LY6E Human HEK293 Fc 9970-L6 Inhibits IFN-gamma and IL-2 secretion by T cells
EMMPRIN/CD147 Human NS0 Fc, His 972-EMN Induces active MMP-1 secretion by NHLF human normal lung fibroblasts
Mouse NS0 His 772-EM

Proteases

Host cell proteases are involved in coronavirus protein processing and activation. All enzymes listed are bioactive and QC tested to ensure consistency and activity.

Protein Species Source Tag Catalog # Bioactivity
Cathepsin B Human NS0 His 953-CY Cleaves the fluorogenic peptide substrate Z-LR-AMC (Catalog # ES008)
Mouse NS0 His 965-CY
Cathepsin L Human NS0 His 952-CY Cleaves the fluorogenic peptide substrate Z-LR-AMC (Catalog # ES008)
Mouse NS0 His 1515-CY
Furin Human NS0 His 1503-SE Cleaves the fluorogenic peptide substrate pERTKR-AMC (Catalog # ES013)
Mouse CHO His 6450-SE
Elastase/ELA2 Human CHO His 9167-SE Cleaves the fluorogenic peptide substrate, MeOSuc-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin (MeOSuc-AAPV-AMC
Mouse NS0 His 4517-SE

Find More Tools for Coronavirus Research

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