Human mGluR5 (NP_000833) VersaClone cDNA

    
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Preparation and Storage
  • Stability & Storage
    Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: mGluR5
Human metabotropic glutamate receptor 5 (mGluR5; also mGluR5b) is a 150 kDa, 7-transmembrane glycoprotein that belongs to group I of the C-family of G-protein coupled receptors. mGluR5 is constitutively expressed and regulates neuronal ion channel activity. Human mGluR5 is 1212 amino acids (aa) in length and contains an extracellular domain (ECD) of 558 amino acids. Through its ECD, mGluR5 either homodimerizes or heterodimerizes with the Ca2+-sensor receptor. There is one alternate splice form (mGluR5a) that shows a 32 aa deletion between aa 877 - 908 in the cytoplasmic tail. Over aa 19 - 509, human mGluR5 is 98% aa identical to mouse, rat, and canine mGluR5.
  • Long Name:
    Metabotropic Glutamate Receptor 5
  • Entrez Gene IDs:
    2915 (Human); 108071 (Mouse); 24418 (Rat)
  • Alternate Names:
    glutamate receptor, metabotropic 5; GPRC1E; GPRC1EMGLUR5metabotropic glutamate receptor 5; GRM5; mGlu5; mGluR5
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Tocris Small Molecules
Description Application Cat# Citations Images  

Kynurenic acid

0223 13  
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CHPG Sodium salt

3695  
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MTEP hydrochloride

2921 10  
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L-Glutamic acid

0218 7  
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L-Quisqualic acid

0188 8  
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(S)-MCPG

0337 24  
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CHPG

1049 17  
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VU 0360172 hydrochloride

4323  
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AIDA

0904 9  
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PHCCC

1027 8  
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ADX 10059 hydrochloride

4416  
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γDGG

0112 3  
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Theanine

3847  
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VU 29

4458 1  
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VU 0285683

4381  
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D-AP4

0102 3  
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NPEC-caged-(1S,3R)-ACPD

3331  
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ACPT-II

1112 2  
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VU 0357121

4437  
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(S)-3-Hydroxyphenylglycine

0326  
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S-Sulfo-L-cysteine sodium salt

0162  
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L-Cysteinesulfinic acid

0216  
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D-Glutamic acid

0217  
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(RS)-MCPG

0336 12  
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LSN 2463359

5275  
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(RS)-3-Hydroxyphenylglycine

0324  
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Ro 67-4853

4347  
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CDPPB

3235 4  
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CPPHA

4787  
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MFZ 10-7

4438  
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VU 1545

3325  
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DMeOB

1953  
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ACDPP hydrochloride

2254  
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(S)-3-Carboxy-4-hydroxyphenylglycine

0329  
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VU 0360223

4394  
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VU 0409551

5693  
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NPS 2390

4134 1  
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ABP 688

5229  
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SIB 1757

1215 2  
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AZD 2066

5614  
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DFB

1625 1  
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(S)-4-Carboxy-3-hydroxyphenylglycine

0320 1  
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DCB

1952  
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Fenobam

2386 1  
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VersaClone cDNA Plasmids
Description Application Cat# Citations Images  

Rat CXCR5 (NP_445755) VersaClone cDNA

RDC0037
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Mouse CXCR5 (CAA50673) VersaClone cDNA

RDC0036
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