Human mGluR5 (NP_000833) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC1064
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Human mGluR5 (NP_000833) VersaClone cDNA Summary

Product Datasheets

Preparation and Storage

Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: mGluR5

Human metabotropic glutamate receptor 5 (mGluR5; also mGluR5b) is a 150 kDa, 7-transmembrane glycoprotein that belongs to group I of the C-family of G-protein coupled receptors. mGluR5 is constitutively expressed and regulates neuronal ion channel activity. Human mGluR5 is 1212 amino acids (aa) in length and contains an extracellular domain (ECD) of 558 amino acids. Through its ECD, mGluR5 either homodimerizes or heterodimerizes with the Ca2+-sensor receptor. There is one alternate splice form (mGluR5a) that shows a 32 aa deletion between aa 877 - 908 in the cytoplasmic tail. Over aa 19 - 509, human mGluR5 is 98% aa identical to mouse, rat, and canine mGluR5.

Long Name
Metabotropic Glutamate Receptor 5
Entrez Gene IDs
2915 (Human); 108071 (Mouse); 24418 (Rat)
Alternate Names
glutamate receptor, metabotropic 5; GPRC1E; GPRC1EMGLUR5metabotropic glutamate receptor 5; GRM5; mGlu5; mGluR5

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Tocris Small Molecules

MFZ 10-7

LSN 2463359

DMeOB

VU 0357121

VU 0360223

D-Glutamic acid

Ro 67-4853

CPPHA

AZD 2066

ABP 688

Theanine

DCB

VU 0285683

VU 1545

VU 0409551

CHPG Sodium salt

VersaClone cDNA Plasmids

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