51 results for "Coronavirus Antiviral Compounds" in Products

Coronavirus Antiviral Compounds

Coronaviruses are spherical viruses with a large genome (approximately 27 to 32 kb) enclosed in a lipid bilayer with surface glycoprotein projections that give the virus the appearance of having a crown, hence the name coronavirus. There are four types of coronavirus: Alphacoronaviruses and Betacoronaviruses infect only mammals, while Gammacoronavirus and Deltacoronavirus infect birds. In humans coronaviruses cause respiratory tract infections with symptoms ranging from mild, similar to the ...

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Potent inhibitor of SERCA ATPase

Chemical Name: (3S,3aR,4S,6S,6AR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl octanoate
Purity: ≥97%
Potent inhibitor of SERCA ATPase
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mTOR inhibitor; immunosuppressant

Chemical Name: (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
Purity: ≥98%
mTOR inhibitor; immunosuppressant
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Calcineurin inhibitor

Alternate Names: Ciclosporin A
Purity: ≥98%
Calcineurin inhibitor
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Na+/K+ ATPase inhibitor

Chemical Name: 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11α,14,19-pentahydoxycard-20(22)-enolide
Purity: ≥95%
Na+/K+ ATPase inhibitor
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Inhibitor of protein synthesis

Chemical Name: 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione
Purity: ≥97%
Inhibitor of protein synthesis
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Histone deacetylase inhibitor

Alternate Names: VPA,Sodium Valproate
Chemical Name: Sodium 2-propylpentanoate
Histone deacetylase inhibitor
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Non-selective PI 3-kinase inhibitor

Chemical Name: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
Purity: ≥98%
Non-selective PI 3-kinase inhibitor
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Potent calcineurin inhibitor; immunosuppressant

Alternate Names: Tacrolimus,Fujimycin
Chemical Name: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)tetrone
Purity: ≥98%
Potent calcineurin inhibitor; immunosuppressant
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Potent and selective BET bromodomain inhibitor; cell permeable

Chemical Name: (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester
Purity: ≥98%
Potent and selective BET bromodomain inhibitor; cell permeable
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MRP and OAT3 inhibitor

Chemical Name: 4-(Dipropylsulfamoyl)benzoic acid
Purity: ≥98%
MRP and OAT3 inhibitor
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Highly potent pan-Src/Bcr-Abl inhibitor

Alternate Names: BMS-354825
Chemical Name: N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide
Purity: ≥98%
Highly potent pan-Src/Bcr-Abl inhibitor
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Cyclooxygenase inhibitor (COX-1 > COX-2)

Chemical Name: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole
Purity: ≥98%
Cyclooxygenase inhibitor (COX-1 > COX-2)
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DNA synthesis inhibitor

Chemical Name: (+)-2'-Deoxy-2',2'-difluorocytidine hydrochloride
Purity: ≥98%
DNA synthesis inhibitor
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STAT3 inhibitor; also inhibits mTORC1 signaling

Chemical Name: 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
Purity: ≥98%
STAT3 inhibitor; also inhibits mTORC1 signaling
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Cathepsin inhibitor; interferes with autolysosomal digestion

Chemical Name: (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic acid ethyl ester
Purity: ≥98%
Cathepsin inhibitor; interferes with autolysosomal digestion
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Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit

Alternate Names: Gleevec,CGP 57148B
Chemical Name: 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate
Purity: ≥98%
Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit
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Potent and selective JAK1/JAK2 inhibitor; orally bioavailable

Alternate Names: INCB018424
Chemical Name: (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile
Purity: ≥98%
Potent and selective JAK1/JAK2 inhibitor; orally bioavailable
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DNA topoisomerase II inhibitor

Alternate Names: Daunomycin
Chemical Name: (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyransoyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride
Purity: ≥98%
DNA topoisomerase II inhibitor
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Orally active protease inhibitor; inhibits entry of SARS-Cov-2 into lung cells

Chemical Name: 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate
Purity: ≥98%
Orally active protease inhibitor; inhibits entry of SARS-Cov-2 into lung cells
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Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug

Alternate Names: GS-5734
Chemical Name: 2-Ethylbutyl (2S)-2-[[(S)-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy]phenoxyphosphoryl]amino]propanoate
Purity: ≥98%
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug
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Inhibitor of protein synthesis; antileukemic agent

Chemical Name: Cephalotaxine 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate
Purity: ≥98%
Inhibitor of protein synthesis; antileukemic agent
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Serine protease inhibitor; inhibits tryptase

Chemical Name: 4-[(Aminoiminomethyl)amino]benzoic acid 6-(aminoiminomethyl)-2-naphthalenyl ester dimethanesulfonate
Purity: ≥98%
Serine protease inhibitor; inhibits tryptase
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Na+/K+ ATPase inhibitor

Chemical Name: 4-[(3S,5R,8R,9S,10S,12R,13S,14S)-3-[(2S,4S,5R,6R)-5-[(2S,4S,5R,6R)-5-[(2S,4S,5R,6R)-4,5-Dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyl-oxan-2-yl]oxy-4-hydroxy-6-methyl-oxan-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5H-furan-2-one
Purity: ≥98%
Na+/K+ ATPase inhibitor
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Autophagy inhibitor; also TLR9 inhibitor

Chemical Name: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate
Purity: ≥98%
Autophagy inhibitor; also TLR9 inhibitor
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HIV-1 and HIV-2 protease inhibitor

Alternate Names: ABT-538,A-84538,Abbot 84538
Chemical Name: 5-Thiazolylmethyl (3S,4S,6S,9S)-4-hydroxy-12-methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoate
Purity: ≥98%
HIV-1 and HIV-2 protease inhibitor
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