22 results for "P2X Receptor Antagonists" in Products

P2X Receptor Antagonists

P2X Purinergic Receptor Subunits

Each functional P2X receptor is formed from either three identical subunits (homomeric) or a combination of two or three different subunits (heteromeric). Except for P2X6, all subunits can form homomeric receptors, however, P2X7 subunits only form homomeric receptors. Functional receptors are named for their constituent subunits, for example a homomeric receptor composed of P2X7 subunits is called a P2X7 receptor, while a heteromeric receptor composed of P2X2 ...

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Competitive P2X7 antagonist

Chemical Name: 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride
Purity: ≥98%
Competitive P2X7 antagonist
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Highly selective P2X1 antagonist

Chemical Name: 4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid, octasodium salt
Purity: ≥90%
Highly selective P2X1 antagonist
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Potent and selective P2X7 antagonist

Chemical Name: N-[1-[[(Cyanoamino)(5-quinolinylamino)methylene]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide
Purity: ≥97%
Potent and selective P2X7 antagonist
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Non-competitive P2X7 antagonist

Chemical Name: 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl] phenyl isoquinolinesulfonic acid ester
Purity: ≥98%
Non-competitive P2X7 antagonist
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Potent and selective P2X4 antagonist

Chemical Name: 5-(3-Bromophenyl)-1,3-dihydro-2H-benzofuro[3,2-e]-1,4-diazepin-2-one
Purity: ≥98%
Potent and selective P2X4 antagonist
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Potent and selective P2X antagonist

Chemical Name: 2',3'-O-(2,4,6-Trinitrophenyl)adenosine-5'-triphosphate tetra(triethylammonium) salt
Purity: ≥95%
Potent and selective P2X antagonist
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Potent and selective human P2X7 antagonist

Chemical Name: 3-[1-[[(3'-Nitro[1,1'-biphenyl]-4-yl)oxy]methyl]-3-(4-pyridinyl)propyl]-2,4-thiazolidinedione
Purity: ≥98%
Potent and selective human P2X7 antagonist
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Potent P2X7 antagonist

Chemical Name: N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide dihydrochloride
Purity: ≥98%
Potent P2X7 antagonist
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Non-selective P2 antagonist

Chemical Name: 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
Purity: ≥98%
Non-selective P2 antagonist
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Non-selective P2 antagonist

Chemical Name: Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid tetrasodium salt
Non-selective P2 antagonist
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Selective P2Y11 and P2X1 antagonist

Chemical Name: 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-fluoro-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
Purity: ≥90%
Selective P2Y11 and P2X1 antagonist
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Potent and selective P2X7 antagonist

Chemical Name: N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine
Purity: ≥98%
Potent and selective P2X7 antagonist
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Non-selective P2X antagonist

Chemical Name: Pyridoxalphosphate-6-azophenyl-2',5'-disulfonic acid tetrasodium salt
Non-selective P2X antagonist
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Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist

Chemical Name: 6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)bis[4-amino- 5-hydroxy-1,3-naphthalenedisulphonic acid] tetrasodium salt
Purity: ≥90%
Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist
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Potent and selective P2X1 antagonist

Chemical Name: 8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
Purity: ≥95%
Potent and selective P2X1 antagonist
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Selective and competitive P2X1 antagonist

Chemical Name: 8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid, hexasodium salt
Selective and competitive P2X1 antagonist
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Potent and selective P2X7 antagonist; brain penetrant

Chemical Name: 2-(Phenylthio)-N-[[tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-yl]methyl-3-pyridinecarboxamide
Purity: ≥98%
Potent and selective P2X7 antagonist; brain penetrant
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Selective P2X4 allosteric antagonist

Chemical Name: N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea
Purity: ≥98%
Selective P2X4 allosteric antagonist
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Potent P2X3 antagonist

Chemical Name: 4,4',4'',4'''-[Carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakisbenzenesulfonic acid tetrasodium salt
Purity: ≥90%
Potent P2X3 antagonist
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Selective P2X3 and P2X2/3 antagonist

Chemical Name: 5-[[4,5-Dimethoxy-2-(methylethyl)phenyl]methyl]-2,4-pyrimidinediamine
Purity: ≥98%
Selective P2X3 and P2X2/3 antagonist
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Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive

Chemical Name: 5-[[[(3-Phenoxyphenyl)methyl][(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]carbonyl]-1,2,4-benzenetricarboxylic acid disodium salt
Purity: ≥98%
Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive
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Selective P2X4 antagonist

Chemical Name: N-[3-(Aminosulfonyl)-4-(3-chlorophenoxy)phenyl]benzeneacetamide
Purity: ≥98%
Selective P2X4 antagonist
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