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SB 431542 synthesized to cGMP guidelines
Highly selective GSK-3 inhibitor; acts as Wnt activator
EZH2 histone methyltransferase inhibitor
Potent and selective inhibitor of TGF-βRI
Potent inhibitor of MEK1/2
Enhances the generation of iPSCs; increases reprogramming efficiency
ROCK inhibitor; improves the efficiency of fibroblast reprogramming and induction of iPSCs
Histone deacetylase inhibitor
γ-secretase inhibitor; inhibits Notch pathway
Retinoic acid analog; RAR agonist
Potent histone deacetylase inhibitor
3-Deazaneplanocin A hydrochloride synthesized to Ancillary Material Grade
Irreversible inhibitor of LSD1; also inhibits MAO
Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability
Non-nucleoside DNA methyltransferase inhibitor
DNA methyltransferase inhibitor
GSK-3β inhibitor; also inhibits cdks
Inhibitor of p53-mitochondrial binding
Sterile-filtered 10 mM solution of CHIR 99021 pre-dissolved in DMSO
L-Ascorbic acid synthesized to Ancillary Material Grade