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Highly selective GSK-3 inhibitor
Potent inhibitor of MEK1/2
Enhances the generation of iPSCs; increases reprogramming efficiency
Histone deacetylase inhibitor
EZH2 histone methyltransferase inhibitor
Potent and selective inhibitor of TGF-βRI
Potent histone deacetylase inhibitor
Improves the efficiency of fibroblast reprogramming and induction of iPSCs
γ-secretase inhibitor; inhibits Notch pathway
Retinoic acid analog; RAR agonist
DNA methyltransferase inhibitor
Irreversible inhibitor of LSD1; also inhibits MAO
GSK-3β inhibitor; also inhibits cdks
Inhibitor of p53-mitochondrial binding
Non-nucleoside DNA methyltransferase inhibitor
Oct4 activator; enhances iPSC reprogramming efficiency
SB 431542 synthesized to cGMP guidelines
DAPT synthesized to cGMP guidelines
