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Highly selective GSK-3 inhibitor
Potent inhibitor of MEK1/2
Histone deacetylase inhibitor
Enhances the generation of iPSCs; increases reprogramming efficiency
Ca2+ channel activator (L-type)
Improves the efficiency of fibroblast reprogramming and induction of iPSCs
Potent histone deacetylase inhibitor
γ-secretase inhibitor; inhibits Notch pathway
Retinoic acid analog; RAR agonist
Potent and selective inhibitor of TGF-βRI
Irreversible inhibitor of LSD1; also inhibits MAO
DNA methyltransferase inhibitor
EZH2 histone methyltransferase inhibitor
Potent cyclin-dependent kinase inhibitor. Also inhibits GSK-3
Inhibitor of p53-mitochondrial binding
Non-nucleoside DNA methyltransferase inhibitor
Oct4 activator; enhances iPSC reprogramming efficiency
SB 431542 synthesized to cGMP guidelines
DAPT synthesized to cGMP guidelines
