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SB 431542 synthesized to cGMP guidelines
Highly selective GSK-3 inhibitor; acts as Wnt activator
EZH2 histone methyltransferase inhibitor
Enhances the generation of iPSCs; increases reprogramming efficiency
Potent and selective inhibitor of TGF-βRI
Potent inhibitor of MEK1/2
Histone deacetylase inhibitor
ROCK inhibitor ; improves the efficiency of fibroblast reprogramming and induction of iPSCs
Retinoic acid analog; RAR agonist
3-Deazaneplanocin A hydrochloride synthesized to Ancillary Material Grade
Potent histone deacetylase inhibitor
γ-secretase inhibitor; inhibits Notch pathway
GSK-3β inhibitor; also inhibits cdks
DNA methyltransferase inhibitor
Irreversible inhibitor of LSD1; also inhibits MAO
Inhibitor of p53-mitochondrial binding
Non-nucleoside DNA methyltransferase inhibitor
DBZ synthesized to Ancillary Material Grade