Compounds for ESC/iPSC Cell Differentiation: Products

DMSO, sterile filtered, wide ranging applications in cell culture, cryopreservation and organic chemistry. Solvent for polar and nonpolar compounds

Potent AMPK inhibitor; also BMP type I receptor inhibitor

Endogenous retinoic acid receptor agonist

CK1 inhibitor

Highly potent PORCN inhibitor

XAV 939 synthesized to cGMP guidelines

Potent inhibitor of Wnt/β-catenin signaling

Endogenous agonist for the transcription factor aryl hydrocarbon receptor

Histone deacetylase inhibitor

Induces definitive endoderm formation in mouse and human ESCs

Adenosine deaminase inhibitor

Selective covalent PPARγ antagonist

Synthetic retinoid; induces differentiation of stem cells

Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation

Selective inhibitor of TGF-β signaling; induces cardiomyocyte differentiation in ESCs

Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation

T3 synthesized to Ancillary Material Grade

Epithelial KCa channel activator

DNA methyltransferase and cytidine deaminase inhibitor

Potent SCD-1 inhibitor

SCD-1 inhibitor

Rho/SRF pathway inhibitor; induces intermediate mesoderm differentiation from ESCs

Enhances iPSC-derived hepatocyte differentiation and maturation

Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes

Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells

Intracellular cryoprotective agent

A 83-01 synthesized to Ancillary Material Grade

ISX 9 synthesized to Ancillary Material Grade

WIKI4 synthesized to Ancillary Material Grade

Estrogen-related receptor γ agonist; promotes maturation of hiPSC-derived cardiomyocytes

Glutathione (GSH) precursor; maintains stem cell function in culture.