Products for Angiogenesis Research

  1. Saharinen, P. et al. (2008) Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. Nat. Cell Biol. 10:527.

    Recombinant Human Angiopoietin-1 (Catalog # 923-AN)

    Recombinant Human Angiopoietin-2 (Catalog # 623-AN)

    Sample: Mouse b-END3 brain-derived microvascular endothelial cells, human umbilical vein, and human EA.hy926 endothelial cells
    Application: Bioassay- signaling

    Recombinant Human Tie-2/Fc Chimera (Catalog # 313-TI)

    Sample: Human umbilical vein endothelial cells
    Application: Pull-down and Cell adhesion assays

    Recombinant Human VEGF R3/Flt-4/Fc Chimera (Catalog # 349-F4)

    Recombinant Human Tie-1/Fc Chimera (Catalog # 619-TI)

    Sample: Human umbilical vein endothelial cells
    Application: Pull-down and Bead aggregation assays

    Phospho-Tie-2 (Y992) Polyclonal Antibody (Catalog # AF2720)

    Human Tie-2 Polyclonal Antibody (Catalog # AF313)

    Sample: Human umbilical vein, human pulmonary microvascular, and human EA.hy926 endothelial cells
    Applications: Western Blot, Immunohistochemistry
  2. Shim, W. et al. (2008) Structural stability of neoangiogenic intramyocardial microvessels supports functional recovery in chronic ischemic myocardium.
    J. Mol. Cell. Cardiol. 45:70.

    Human Angiopoietin-1 Quantikine® ELISA Kit (Catalog # DANG10)

    Human Angiopoietin-2 Quantikine ELISA Kit (Catalog # DANG20)

    Human VEGF Quantikine ELISA Kit (Catalog # DVE00)

    Sample: Porcine myocardium homogenate
    Application: ELISA
  3. Bae, Y. et al. (2009) Upregulation of fibroblast growth factor-2 by visfatin that promotes endothelial angiogenesis. Biochem. Biophys. Res. Commun. 379:206.

    Human FGF basic Quantikine ELISA Kit (Catalog # DFB50)

    Sample: Human microvascular endothelial cell supernates
    Application: ELISA

    Human FGF basic Polyclonal Antibody (Catalog # AF-233-NA)

    Sample: Rat aortic ring explant
    Application: Neutralization

    Recombinant Human FGF basic (Catalog # 233-FB)

    Sample: Rat aortic ring explant
    Application: Bioassay- microvessel outgrowth
  4. Crawford, Y. et al. (2009) PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell 15:21.

    Recombinant Human PDGF-DD (Catalog # 1159-SB)

    Recombinant Mouse VEGF 164 (Catalog # 493-MV)

    Recombinant Human PDGF-CC (Catalog # 1687-CC)

    Application: Western blot specificity control

    Recombinant Human/Rhesus Macaque/Feline CXCL12/SDF-1 alpha (Catalog # 350-NS)

    Sample: Mouse normal skin and tumor-associated fibroblasts
    Applications: In vivo Matrigel® plug assay, Western blot specificity control

    Recombinant Mouse PDGF-CC (Catalog # 1447-PC)

    Sample: Mouse normal skin and tumor-associated fibroblasts and endothelial cells
    Applications: In vivo Matrigel plug assay, Bioassay- migration, Western blot positive control

    Mouse PDGF-C Polyclonal Antibody (Catalog # AF1447)

    Sample: Mouse normal skin and tumor-associated fibroblasts; Recombinant mouse PDGF-CC
    Applications: Neutralization of In vivo Matrigel plug assay, Western blot

    Mouse VEGF Quantikine ELISA Kit (Catalog # MMV00)

    Sample: Mouse normal skin and tumor-associated fibroblast tumor supernates
    Application: ELISA
  5. Zacchigna, S. et al. (2008) Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice. J. Clin. Invest. 118:2062.

    Rat Neuropilin-1 Polyclonal Antibody (Catalog # AF566)

    Rat Neuropilin-2 Polyclonal Antibody (Catalog # AF567)

    Sample: Mouse muscle
    Application: Immunohistochemistry

    Recombinant Human VEGF 165 (Catalog # 293-VE)

    Recombinant Human VEGF (aa 207-318) (Catalog # 298-VS)

    Recombinant Human Semaphorin 3A/Fc Chimera (Catalog # 1250-S3)

    Sample: Human smooth muscle and endothelial cells
    Application: Bioassay- migration
  6. Tammela, T. et al. (2008) Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 454:656.

    Mouse VEGF R3/Flt-4 Polyclonal Antibody (Catalog # AF743)

    Mouse VEGF R2/Flk-1 Polyclonal Antibody (Catalog # AF644)

    Mouse DLL4 Polyclonal Antibody (Catalog # AF1389)

    Sample: Mouse retina and skin
    Application: Immunohistochemistry
  7. Zhang, Z. et al. (2008) a2b1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner. Blood 111:1980.

    Recombinant Mouse VEGF 164 (Catalog # 493-MV)

    Recombinant Human PlGF (Catalog # 264-PG)

    Sample: Mouse and mouse thoracic aortal explant
    Application: In vivo Matrigel plug assay, Bioassay- aortic ring assay

    Recombinant Human VEGF-C (Catalog # 2179-VC)

    Sample: Mouse
    Application: In vivo Matrigel plug assay

    Mouse VEGF R2/Flk-1 Monoclonal Antibody (Catalog # MAB4431)

    Mouse VEGF R1/Flt-1 Polyclonal Antibody (Catalog # AF471)

    Sample: Tumor, pulmonary endothelial cells, and lysates
    Application: Immunohistochemistry, Neutralization, Western blot

    Mouse PlGF-2 Quantikine ELISA Kit (Catalog # MP200)

    Mouse VEGF Quantikine ELISA Kit (Catalog # MMV00)

    Sample: Mouse Lewis lung carcinoma and B16-F10 melanoma cell line supernates
    Application: ELISA
  8. Devy, L et al. (2009) Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis. Cancer Res. 69:1517.

    Recombinant Human MMP-14 (Catalog # 918-MP)

    Sample: Human Fab displaying phage library
    Application: Library screening and selection

    Human VEGF Monoclonal Antibody (Catalog # MAB293)

    Sample: Human umbilical vein endothelial cells
    Application: Neutralization

    Human MMP-14 Monoclonal Antibody (Catalog # MAB9181)

    Sample: Human umbilical vein endothelial, HT-1080 fibrosarcoma, MDA-MB-231, and MCF-7 breast cancer cell lysates
    Application: Western Blot

Matrigel is a registereds trademark of Becton, Dickinson and Company.
Quantikine is a registered trademark of R&D Systems, Inc.