Human CCR7 Antibody

Clone 150503 was used by HLDA to establish CD designation.
(68 citations)
(1 Review)
  
  • Species Reactivity
    Human
  • Specificity
    Detects human CCR7.
  • Source
    Monoclonal Mouse IgG2A Clone # 150503
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    Human CCR7 transfectants
    Met1-Pro378
    Accession # AAA58615
  • Formulation
    Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
  • Endotoxin Level
    <0.10 EU per 1 μg of the antibody by the LAL method.
  • Label
    Unconjugated
Applications
  •  
    Recommended
    Concentration
    Sample
  • Flow Cytometry
    0.25 µg/106 cells
    See below
  • CyTOF-reported
    Mei, H.E. et al. (2015) J. Immunol. 194: 2022. Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
  • Immunocytochemistry
    8-25 µg/mL
    See below
  • Neutralization
    Measured by its ability to neutralize CCL19/MIP‑3 beta -induced chemotaxis in the BaF3 mouse pro‑B cell line transfected with human CCR7. The Neutralization Dose (ND50) is typically 1-5 µg/mL in the presence of 50 ng/mL Recombinant Human CCL19/MIP‑3 beta.
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Immunocytochemistry
CCR7 in Human PBMCs.

CCR7 was detected in immersion fixed human peripheral blood mononuclear cells (PBMCs) using 25 µg/mL Mouse Anti-Human CCR7 Monoclonal Antibody (Catalog # MAB197) for 3 hours at room temperature. Cells were stained (red) and counterstained (green). View our protocol for Fluorescent ICC Staining of Non-adherent Cells.

Detection of CCR7 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD4 PE‑conjugated Monoclonal Antibody (Catalog # FAB3791P) and either (A) Mouse Anti-Human CCR7 Monoclonal Antibody (Catalog # MAB197) or (B) Mouse IgG2A Isotype Control (Catalog # MAB003) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B). View our protocol for Staining Membrane-associated Proteins.
Chemotaxis Induced by CCL19/MIP‑3 beta and Neutral­ization by Human CCR7 Antibody. Recombinant Human CCL19/MIP‑3 beta (Catalog # 361‑MI) chemoattracts the BaF3 mouse pro‑B cell line transfected with human CCR7 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Human CCL19/MIP‑3 beta (50 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human CCR7 Monoclonal Antibody (Catalog # MAB197). The ND50 is typically 1-5 µg/mL.
Preparation and Storage
  • Reconstitution
    Reconstitute at 0.5 mg/mL in sterile PBS.
  • Shipping
    The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
  • Stability & Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    • 12 months from date of receipt, -20 to -70 °C as supplied.
    • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
    • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CCR7

CCR7 is a 7 transmembrane G protein coupled chemokine receptor. CCR7 is expressed on T cells and mature dendritic cells and transduces chemotactic signals in response to CCL19 and CCL21. Human CCR7 shares 87% amino acid sequence identity with mouse CCR7.

  • Entrez Gene IDs:
    1236 (Human); 12775 (Mouse); 287673 (Rat)
  • Alternate Names:
    BLR2C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR7; CCR-7; CD197 antigen; CD197; CDw197CC chemokine receptor 7; chemokine (C-C motif) receptor 7; CMKBR7chemokine (C-C) receptor 7; EBI1EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus induced G-protein coupled receptor; Epstein-Barr virus-induced G-protein coupled receptor 1; EVI1; lymphocyte-specific G protein-coupled peptide receptor; MIP-3 beta receptor
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

68 Citations: Showing 1 - 10
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Species
Applications
Sample Type
  1. pERK-dependent defective TCR-mediated activation of CD4(+) T cells in end-stage renal disease patients
    Authors: L Huang, NHR Litjens, NM Kannegiete, M Klepper, CC Baan, MGH Betjes
    Immun Ageing, 2017;14(0):14.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  2. Inducible activation of MyD88 and CD40 in CAR T-cells results in controllable and potent antitumor activity in preclinical solid tumor models
    Authors: M Mata, C Gerken, P Nguyen, G Krenciute, DM Spencer, S Gottschalk
    Cancer Discov, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  3. Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver
    Authors: S Pichyangku, MD Spring, K Yongvanitc, U Kum-Arb, A Limsalakpe, R Im-Erbsin, R Ubalee, P Vanachayan, EJ Remarque, E Angov, PL Smith, DL Saunders
    PLoS ONE, 2017;12(2):e0171826.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Flow
  4. Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use
    Authors: JMJ Van den Be, ELJM Smits, M Versteven, H De Reu, ZN Berneman, VFI Van Tendel, E Lion
    J Immunol Res, 2017;2017(0):1975902.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  5. Interferon-?-inducible Dendritic Cells Matured with OK-432 Exhibit TRAIL and Fas Ligand Pathway-mediated Killer Activity
    Authors: T Koya, R Yanagisawa, Y Higuchi, K Sano, S Shimodaira
    Sci Rep, 2017;7(0):42145.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  6. Regulation of CCR7-dependent cell migration through�CCR7 homodimer formation
    Authors: D Kobayashi, M Endo, H Ochi, H Hojo, M Miyasaka, H Hayasaka
    Sci Rep, 2017;7(1):8536.
    Species: Human
    Sample Type: Whole Cells
    Application: ICC
  7. Jak3 is involved in CCR7-dependent migration and invasion in metastatic squamous cell carcinoma of the head and neck
    Authors: Z Zhang, F Liu, Z Li, D Wang, R Li, C Sun
    Oncol Lett, 2017;13(5):3191-3197.
    Species: Human
    Sample Type: Cell Lysates
    Application: Neut
  8. Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques
    Authors: SM Nguyen, KM Antony, DM Dudley, S Kohn, HA Simmons, B Wolfe, MS Salamat, LBC Teixeira, GJ Wiepz, TH Thoong, MT Aliota, AM Weiler, GL Barry, KL Weisgrau, LJ Vosler, MS Mohns, ME Breitbach, LM Stewart, MN Rasheed, CM Newman, ME Graham, OE Wieben, PA Turski, KM Johnson, J Post, JM Hayes, N Schultz-Da, ML Schotzko, JA Eudailey, SR Permar, EG Rakasz, EL Mohr, S Capuano, AF Tarantal, JE Osorio, SL O'Connor, TC Friedrich, DH O'Connor, TG Golos
    PLoS Pathog., 2017;13(5):e1006378.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Flow
  9. Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages
    Authors: F Bellora, A Dondero, MV Corrias, B Casu, S Regis, F Caliendo, A Moretta, M Cazzola, C Elena, L Vinti, F Locatelli, C Bottino, R Castriconi
    J. Immunol., 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  10. Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction
    Nat Commun, 2016;7(0):13895.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  11. Dengue virus infection induces interferon-lambda1 to facilitate cell migration
    Sci Rep, 2016;6(0):24530.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  12. Compartmentalization of Total and Virus-Specific Tissue-Resident Memory CD8+ T Cells in Human Lymphoid Organs
    PLoS Pathog, 2016;12(8):e1005799.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  13. Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  14. IL-21 promotes the expansion of CD27+ CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells.
    Authors: Santegoets S, Turksma A, Suhoski M, Stam A, Albelda S, Hooijberg E, Scheper R, van den Eertwegh A, Gerritsen W, Powell D, June C, de Gruijl T
    J Transl Med, 2015;11(0):37.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  15. Enhanced Chemokine Receptor Recycling and Impaired S1P1 Expression Promote Leukemic Cell Infiltration of Lymph Nodes in Chronic Lymphocytic Leukemia.
    Authors: Patrussi L, Capitani N, Martini V, Pizzi M, Trimarco V, Frezzato F, Marino F, Semenzato G, Trentin L, Baldari C
    Cancer Res, 2015;75(19):4153-63.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  16. Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques.
    Authors: Okoye A, Rohankhedkar M, Konfe A, Abana C, Reyes M, Clock J, Duell D, Sylwester A, Sammader P, Legasse A, Park B, Axthelm M, Nikolich-Zugich J, Picker L
    J Immunol, 2015;195(9):4292-305.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Flow
  17. Tissue Distribution of Memory T and B Cells in Rhesus Monkeys following Influenza A Infection.
    Authors: Pichyangkul S, Yongvanitchit K, Limsalakpetch A, Kum-Arb U, Im-Erbsin R, Boonnak K, Thitithayanont A, Jongkaewwattana A, Wiboon-ut S, Mongkolsirichaikul D, Mahanonda R, Spring M, Chuang I, Mason C, Saunders D
    J Immunol, 2015;195(9):4378-86.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Flow
  18. Trypsin, Tryptase, and Thrombin Polarize Macrophages towards a Pro-Fibrotic M2a Phenotype.
    Authors: White M, Gomer R
    PLoS ONE, 2015;10(9):e0138748.
    Species: Human
    Sample Type: Whole Cells
    Application: IHC Not Specified
  19. Barcoding of live human peripheral blood mononuclear cells for multiplexed mass cytometry.
    Authors: Mei H, Leipold M, Schulz A, Chester C, Maecker H
    J Immunol, 2015;194(4):2022-31.
    Species: Human
    Sample Type: Whole Cells
    Application: CyTof
  20. Prognostic markers for patient outcome following vaccination with multiple MHC Class I/II-restricted WT1 peptide-pulsed dendritic cells plus chemotherapy for pancreatic cancer.
    Authors: Takakura K, Koido S, Kan S, Yoshida K, Mori M, Hirano Y, Ito Z, Kobayashi H, Takami S, Matsumoto Y, Kajihara M, Misawa T, Okamoto M, Sugiyama H, Homma S, Ohkusa T, Tajiri H
    Anticancer Res, 2015;35(1):555-62.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  21. CD20+ B cell depletion alters T cell homing.
    Authors: Kap, Yolanda, van Driel, Nikki, Laman, Jon D, Tak, Paul P, 't Hart, Bert A
    J Immunol, 2014;192(9):4242-53.
    Species: Marmoset
    Sample Type: Whole Cells
    Application: Flow
  22. Proteome-wide analysis of HIV-specific naive and memory CD4(+) T cells in unexposed blood donors.
    Authors: Campion S, Brodie T, Fischer W, Korber B, Rossetti A, Goonetilleke N, McMichael A, Sallusto F
    J Exp Med, 2014;211(7):1273-80.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  23. CD56(bright)perforin(low) noncytotoxic human NK cells are abundant in both healthy and neoplastic solid tissues and recirculate to secondary lymphoid organs via afferent lymph.
    Authors: Carrega, Paolo, Bonaccorsi, Irene, Di Carlo, Emma, Morandi, Barbara, Paul, Petra, Rizzello, Valeria, Cipollone, Giuseppe, Navarra, Giuseppe, Mingari, Maria Cr, Moretta, Lorenzo, Ferlazzo, Guido
    J Immunol, 2014;192(8):3805-15.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  24. Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15.
    Authors: Xu Y, Zhang M, Ramos C, Durett A, Liu E, Dakhova O, Liu H, Creighton C, Gee A, Heslop H, Rooney C, Savoldo B, Dotti G
    Blood, 2014;123(24):3750-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  25. Priming by chemokines restricts lateral mobility of the adhesion receptor LFA-1 and restores adhesion to ICAM-1 nano-aggregates on human mature dendritic cells.
    Authors: Borgman K, van Zanten T, Manzo C, Cabezon R, Cambi A, Benitez-Ribas D, Garcia-Parajo M
    PLoS ONE, 2014;9(6):e99589.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  26. Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation.
    Authors: Pinto S, Martinez-Romero A, O'Connor J, Gil-Benso R, San-Miguel T, Terradez L, Monteagudo C, Callaghan R
    BMC Cancer, 2014;14(0):118.
    Species: Human
    Sample Type: Whole Cells
    Application: ICC Fresh
  27. Adoptive transfer of EBV specific CD8+ T cell clones can transiently control EBV infection in humanized mice.
    Authors: Antsiferova O, Muller A, Ramer P, Chijioke O, Chatterjee B, Raykova A, Planas R, Sospedra M, Shumilov A, Tsai M, Delecluse H, Munz C
    PLoS Pathog, 2014;10(8):e1004333.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  28. The MEC1 and MEC2 lines represent two CLL subclones in different stages of progression towards prolymphocytic leukemia.
    Authors: Rasul E, Salamon D, Nagy N, Leveau B, Banati F, Szenthe K, Koroknai A, Minarovits J, Klein G, Klein E
    PLoS ONE, 2014;9(8):e106008.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  29. Phase I clinical trial of fibronectin CH296-stimulated T cell therapy in patients with advanced cancer.
    Authors: Ishikawa, Takeshi, Kokura, Satoshi, Enoki, Tatsuji, Sakamoto, Naoyuki, Okayama, Tetsuya, Ideno, Mitsuko, Mineno, Junichi, Uno, Kazuko, Yoshida, Naohisa, Kamada, Kazuhiro, Katada, Kazuhiro, Uchiyama, Kazuhiko, Handa, Osamu, Takagi, Tomohisa, Konishi, Hideyuki, Yagi, Nobuaki, Naito, Yuji, Itoh, Yoshito, Yoshikawa, Toshikaz
    PLoS ONE, 2014;9(1):e83786.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  30. Oxygen regulates human cytotrophoblast migration by controlling chemokine and receptor expression.
    Authors: Schanz A, Red-Horse K, Hess A, Baston-Bust D, Heiss C, Krussel J
    Placenta, 2014;35(12):1089-94.
    Species: Human
    Sample Type: Cell Lysates
    Application: WB
  31. Development and function of human innate immune cells in a humanized mouse model.
    Authors: Rongvaux, Anthony, Willinger, Tim, Martinek, Jan, Strowig, Till, Gearty, Sofia V, Teichmann, Lino L, Saito, Yasuyuki, Marches, Florenti, Halene, Stephani, Palucka, A Karoli, Manz, Markus G, Flavell, Richard
    Nat Biotechnol, 2014;32(4):364-72.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow
  32. Cytokine production and antigen recognition by human mucosal homing conjunctival effector memory CD8+ T cells.
    Authors: Williams G, Pachnio A, Long H, Rauz S, Curnow S
    Invest Ophthalmol Vis Sci, 2014;55(12):8523-30.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  33. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis.
    Authors: Lee E, Fertig E, Jin K, Sukumar S, Pandey N, Popel A
    Nat Commun, 2014;5(0):4715.
    Species: Human
    Sample Type: Whole Cells
    Application: Blocking
  34. Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma.
    Authors: Somovilla-Crespo B, Alfonso-Perez M, Cuesta-Mateos C, Carballo-de Dios C, Beltran A, Terron F, Perez-Villar J, Gamallo-Amat C, Perez-Chacon G, Fernandez-Ruiz E, Zapata J, Munoz-Calleja C
    J Hematol Oncol, 2013;6(0):89.
    Species: Human
    Sample Type: Whole Cells
    Application: Neut
  35. Neuroblastoma-derived TGF-beta1 modulates the chemokine receptor repertoire of human resting NK cells.
    Authors: Castriconi R, Dondero A, Bellora F, Moretta L, Castellano A, Locatelli F, Corrias M, Moretta A, Bottino C
    J Immunol, 2013;190(10):5321-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  36. TCR-driven transendothelial migration of human effector memory CD4 T cells involves Vav, Rac, and myosin IIA.
    Authors: Manes, Thomas D, Pober, Jordan S
    J Immunol, 2013;190(7):3079-88.
    Species: Human
    Sample Type: Whole Cells
    Application: Functional Assay
  37. Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency.
    Authors: Mazerolles F, Picard C, Kracker S, Fischer A, Durandy A
    J Allergy Clin Immunol, 2013;131(4):1146-56, 1156.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  38. Functional diversity of human vaginal APC subsets in directing T-cell responses.
    Authors: Duluc, D, Gannevat, J, Anguiano, E, Zurawski, S, Carley, M, Boreham, M, Stecher, J, Dullaers, M, Banchereau, J, Oh, S
    Mucosal Immunol, 2013;6(3):626-38.
    Species: Human
    Sample Type: Tissue Homogenates
    Application: Flow
  39. NK cells from malignant pleural effusions are not anergic but produce cytokines and display strong antitumor activity on short-term IL-2 activation.
    Authors: Vacca P, Martini S, Garelli V, Passalacqua G, Moretta L, Mingari M
    Eur J Immunol, 2013;43(2):550-61.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  40. Accelerated heterologous adenovirus prime-boost SIV vaccine in neonatal rhesus monkeys.
    Oncogene, 2012;86(15):7829-35.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Flow
  41. Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta.
    Authors: Zielinski CE, Mele F, Aschenbrenner D, Jarrossay D, Ronchi F, Gattorno M, Monticelli S, Lanzavecchia A, Sallusto F
    Nature, 2012;484(7395):514-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  42. Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells.
    Authors: Islam SA, Chang DS, Colvin RA
    Nat. Immunol., 2011;12(2):167-77.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  43. Early Induction of Polyfunctional Simian Immunodeficiency Virus (SIV)-Specific T Lymphocytes and Rapid Disappearance of SIV from Lymph Nodes of Sooty Mangabeys during Primary Infection.
    Authors: Meythaler M, Wang Z, Martinot A, Pryputniewicz S, Kasheta M, McClure HM, O'Neil SP, Kaur A
    J. Immunol., 2011;186(9):5151-61.
    Species: Primate - Cercocebus torquatus (Sooty Mangabey)
    Sample Type: Whole Cells
    Application: Flow
  44. Identification of human NK17/NK1 cells.
    Authors: Pandya AD, Al-Jaderi Z, Hoglund RA, Holmoy T, Harbo HF, Norgauer J, Maghazachi AA
    PLoS ONE, 2011;6(10):e26780.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  45. Blocking of alpha4beta7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques.
    Authors: Ansari AA, Reimann KA, Mayne AE, Takahashi Y, Stephenson ST, Wang R, Wang X, Li J, Price AA, Little DM, Zaidi M, Lyles R, Villinger F
    J. Immunol., 2011;186(2):1044-59.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Flow
  46. CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets.
    Authors: Yu J, Mao HC, Wei M, Hughes T, Zhang J, Park IK, Liu S, McClory S, Marcucci G, Trotta R, Caligiuri MA
    Blood, 2010;115(2):274-81.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  47. Expression of podoplanin and other lymphatic markers in the human anterior eye segment.
    Authors: Birke K, Lutjen-Drecoll E, Kerjaschki D, Birke MT
    Invest. Ophthalmol. Vis. Sci., 2010;51(1):344-54.
    Species: Human
    Sample Type: Whole Tissue
    Application: IHC
  48. Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones during acute and chronic infection of rhesus macaques.
    Authors: Bolton DL, Minang JT, Trivett MT, Song K, Tuscher JJ, Li Y, Piatak M, O'Connor D, Lifson JD, Roederer M, Ohlen C
    J. Immunol., 2010;184(1):303-14.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Flow
  49. Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones in rhesus macaques during acute infection.
    Authors: Minang JT, Trivett MT, Bolton DL, Trubey CM, Estes JD, Li Y, Smedley J, Pung R, Rosati M, Jalah R, Pavlakis GN, Felber BK, Piatak M, Roederer M, Lifson JD, Ott DE, Ohlen C
    J. Immunol., 2010;184(1):315-26.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Flow
  50. CCL21 overexpressed on lymphatic vessels drives thymic hyperplasia in myasthenia.
    Authors: Berrih-Aknin S, Ruhlmann N, Bismuth J, Cizeron-Clairac G, Zelman E, Shachar I, Dartevelle P, de Rosbo NK, Le Panse R
    Ann. Neurol., 2009;66(4):521-31.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  51. RNA-loaded CD40-activated B cells stimulate antigen-specific T-cell responses in dogs with spontaneous lymphoma.
    Authors: Mason NJ, Coughlin CM, Overley B, Cohen JN, Mitchell EL, Colligon TA, Clifford CA, Zurbriggen A, Sorenmo KU, Vonderheide RH
    Gene Ther., 2008;15(13):955-65.
    Species: Canine
    Sample Type: Whole Cells
    Application: Flow
  52. Post-apoptotic tumors are more palatable to dendritic cells and enhance their antigen cross-presentation activity.
    Authors: Brusa D, Garetto S, Chiorino G, Scatolini M, Migliore E, Camussi G, Matera L
    Vaccine, 2008;26(50):6422-32.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  53. Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling.
    Authors: Shields JD, Fleury ME, Yong C, Tomei AA, Randolph GJ, Swartz MA
    Cancer Cell, 2007;11(6):526-38.
    Species: Human
    Sample Type: Cell Lysates
    Application: WB
  54. Prolonged (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate-driven antimicrobial and cytotoxic responses of pulmonary and systemic Vgamma2Vdelta2 T cells in macaques.
    Authors: Ali Z, Shao L, Halliday L, Reichenberg A, Hintz M, Jomaa H, Chen ZW
    J. Immunol., 2007;179(12):8287-96.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Type: Whole Cells
    Application: Flow
  55. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells.
    Authors: Kang SG, Lim HW, Andrisani OM, Broxmeyer HE, Kim CH
    J. Immunol., 2007;179(6):3724-33.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  56. Idiopathic pulmonary fibrosis fibroblasts migrate and proliferate to CC chemokine ligand 21.
    Authors: Pierce EM, Carpenter K, Jakubzick C, Kunkel SL, Evanoff H, Flaherty KR, Martinez FJ, Toews GB, Hogaboam CM
    Eur. Respir. J., 2007;29(6):1082-93.
    Species: Human
    Sample Type: Cell Lysates
    Application: WB
  57. Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection.
    Authors: Okoye A, Meier-Schellersheim M, Brenchley JM, Hagen SI, Walker JM, Rohankhedkar M, Lum R, Edgar JB, Planer SL, Legasse A, Sylwester AW, Piatak M, Lifson JD, Maino VC, Sodora DL, Douek DC, Axthelm MK, Grossman Z, Picker LJ
    J. Exp. Med., 2007;204(9):2171-85.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Flow
  58. Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.
    Authors: Pierce EM, Carpenter K, Jakubzick C, Kunkel SL, Flaherty KR, Martinez FJ, Hogaboam CM
    Am. J. Pathol., 2007;170(4):1152-64.
    Species: Complex
    Sample Type: Complex Sample Type
    Application: Neut
  59. Transduction with human telomerase reverse transcriptase immortalizes a rhesus macaque CD8+ T cell clone with maintenance of surface marker phenotype and function.
    Authors: Andersen H, Barsov EV, Trivett MT, Trubey CM, Giavedoni LD, Lifson JD, Ott DE, Ohlen C
    AIDS Res. Hum. Retroviruses, 2007;23(3):456-65.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Flow
  60. Vitamins A and D are potent inhibitors of cutaneous lymphocyte-associated antigen expression.
    Authors: Yamanaka K, Dimitroff CJ, Fuhlbrigge RC, Kakeda M, Kurokawa I, Mizutani H, Kupper TS
    J. Allergy Clin. Immunol., 2007;121(1):148-157.e3.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  61. Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
    Authors: Muller A, Sonkoly E, Eulert C, Gerber PA, Kubitza R, Schirlau K, Franken-Kunkel P, Poremba C, Snyderman C, Klotz LO, Ruzicka T, Bier H, Zlotnik A, Whiteside TL, Homey B, Hoffmann TK
    Int. J. Cancer, 2006;118(9):2147-57.
    Species: Human
    Sample Type: Whole Tissue
    Application: IHC Paraffin-embedded
  62. The monoclonal antibody CHO-131 identifies a subset of cutaneous lymphocyte-associated antigen T cells enriched in P-selectin-binding cells.
    Authors: Ni Z, Campbell JJ, Niehans G, Walcheck B
    J. Immunol., 2006;177(7):4742-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  63. The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors.
    Authors: Hirahara K, Liu L, Clark RA, Yamanaka K, Fuhlbrigge RC, Kupper TS
    J. Immunol., 2006;177(7):4488-94.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  64. Trafficking pathways and characterization of CD4 and CD8 cells recruited to the skin of humans experimentally infected with Haemophilus ducreyi.
    Authors: Humphreys TL, Baldridge LA, Billings SD, Campbell JJ, Spinola SM
    Infect. Immun., 2005;73(7):3896-902.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  65. Classification of distinct subtypes of peripheral T-cell lymphoma unspecified, identified by chemokine and chemokine receptor expression: Analysis of prognosis.
    Authors: Ohshima K, Karube K, Kawano R, Tsuchiya T, Suefuji H, Yamaguchi T, Suzumiya J, Kikuchii M
    Int. J. Oncol., 2004;25(3):605-13.
    Species: Human
    Sample Type: Whole Cells
    Application: ICC
  66. Developing neonatal rabbit appendix, a primary lymphoid organ, is seeded by immature blood-borne B cells: evidence for roles for CD62L/PNAd, CCR7/CCL21, alpha4beta1 and LFA-1.
    Authors: Sinha RK, Mage RG
    Dev. Comp. Immunol., 2004;28(7):829-41.
    Species: Rabbit
    Sample Type: Whole Cells
    Application: Flow
  67. Suppressive properties of human CD4+CD25+ regulatory T cells are dependent on CTLA-4 expression.
    Authors: Birebent B, Lorho R, Lechartier H, de Guibert S, Alizadeh M, Vu N, Beauplet A, Robillard N, Semana G
    Eur. J. Immunol., 2004;34(12):3485-96.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  68. Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma.
    Authors: Doubrovina ES, Doubrovin MM, Vider E, Sisson RB, O&amp;amp;apos;Reilly RJ, Dupont B, Vyas YM
    J. Immunol., 2003;171(12):6891-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
Expand to show all 68 Citations
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ApplicationFlow Cytometry
Sample TestedHuman T cells from Cord and Maternal Blood
SpeciesHuman

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