Recombinant Cynomolgus Monkey and Rhesus Macaque Proteins

Cynomolgus Monkey and Rhesus Macaque are widely used animal models. This covers a range of research areas and pathologies such as neurology, reproduction, Parkinson's disease, stroke, malaria, infectious disease, genetics, xenotransplantation, and drug abuse. Cynomolgus is currently a model of choice for immunotherapy researchers interested in the field of checkpoint immunology.

R&D Systems is expanding our line of Recombinant Cynomolgus Monkey proteins. We also offer Custom Services for development of your Cynomolgus protein of choice.

Representative Examples of Protein Activity

Recombinant human IL-18 protein bioactivity
Recombinant Cynomolgus Monkey TIM-3 (Catalog# 7914-TM) inhibits anti-CD3 antibody-induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 0.5-3 µg/mL.
  Recombinant human IL-18 protein bioactivity
Recombinant Rhesus Macaque IL-18 (Catalog # 2548-RM) induces IFN-gamma secretion by KG 1 human acute myelogenous leukemia cells in the presence of TNF-alpha. The ED50 for this effect is 1-4 ng/mL.
Proteins Catalog #
Cynomolgus 4-1BB/TNFRSF9 Fc Chimera 9324-4B
Cynomolgus B7-1/CD80 9244-B1
Cynomolgus B7-H1/PD-L1 Fc Chimera 9326-B7
Cynomolgus B7-H2 9327-B7
Cynomolgus B7-H2 Fc Chimera 9900-B7 New!
Cynomolgus B7-H6 Fc Chimera 8984-B7
Cynomolgus CD19 Fc Chimera 9958-CD New!
Cynomolgus CD200 Fc Chimera 9274-CD
Cynomolgus CD200 R1 Fc Chimera 9357-CD
Cynomolgus CD27/TNFRSF7 Fc  9904-CD New!
Cynomolgus CD38 9834-AC
Cynomolgus CD40/TNFRSF5 9660-CD
Cynomolgus CTLA-4 Fc Chimera 9336-CT
Cynomolgus DcR3/TNFRSF6B Fc Chimera 9297-DC
Cynomolgus DPPIV/CD26 9637-SE
Cynomolgus DNAM-1/CD226 Fc Chimera 9276-DN
Cynomolgus Fc gamma RI/CD64 9239-FC
Cynomolgus Fc gamma RIIA/CD32a  9240-CD
Cynomolgus Fc gamma RIIB  9246-CD
Cynomolgus Fc gamma RIII 9224-FC
Cynomolgus FCAR/CD89 9516-FA
Cynomolgus GITR/TNFRSF18 9428-GR
Cynomolgus HVEM/TNFRSF14 Fc Chimera 9197-HV
Cynomolgus ICOS Fc Chimera 9736-CS 
Cynomolgus IgG1 Fc 9315-HG
Cynomolgus LAG-3 His-tag 9992-L3 New!
Cynomolgus PD-1 His tag 8509-PD
Cynomolgus PD-1 Fc Chimera 8578-PD
Cynomolgus PD-L2/B7-DC Fc Chimera 9178-PL
Cynomolgus Siglec-2/CD22 9864-SL 
Cynomolgus SIRP alpha/CD172a 9519-SA
Cynomolgus TIGIT 9380-TG
Cynomolgus TIM-1/KIM-1/HAVCR Fc Chimera 9676-TM
Cynomolgus TIM-3 Fc Chimera 7914-TM
Cynomolgus TIM-4 Fc Chimera 9384-TM
Cynomolgus TNF RI/TNFRSF1A Fc 9884-TR New!
Cynomolgus VISTA/B7-H5 Fc Chimera      9408-B7
Rhesus Macaque  IFN gamma  961-RM
Rhesus Macaque  IL-12 His tag 3216-RL
Rhesus Macaque  IL-13  2674-RM
Rhesus Macaque  IL-18 2548-RM
Rhesus Macaque  IL-1beta  1318-RL
Rhesus Macaque  IL-4 1577-IL
Rhesus Macaque  IL-5 2707-RM
Rhesus Macaque  TNF-alpha  1070-RM